cGAS in action: Expanding roles in immunity and inflammation von Ablasser, Andrea, Chen, Zhijian J

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The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer von Li, Tuo, Chen, Zhijian J

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DNA-induced liquid phase condensation of cGAS activates innate immune signaling von Du, Mingjian, Chen, Zhijian J

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Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING von Zhang, Xu, Shi, Heping, Wu, Jiaxi, Zhang, Xuewu, Sun, Lijun, Chen, Chuo, Chen, Zhijian J.

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Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing von Chen, Qi, Sun, Lijun, Chen, Zhijian J

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Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids von Wu, Jiaxi, Chen, Zhijian J

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Ubiquitination in signaling to and activation of IKK von Chen, Zhijian J.

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The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling von Cai, Xin, Chiu, Yu-Hsin, Chen, Zhijian J.

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Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway von Zhang, Xuewu, Bai, Xiao-chen, Chen, Zhijian J.

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MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response von Hou, Fajian, Sun, Lijun, Zheng, Hui, Skaug, Brian, Jiang, Qiu-Xing, Chen, Zhijian J.

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cGAS is essential for cellular senescence von Yang, Hui, Wang, Hanze, Ren, Junyao, Chen, Qi, Chen, Zhijian J.

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Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids von Tan, Xiaojun, Sun, Lijun, Chen, Jueqi, Chen, Zhijian J

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Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation von Cai, Xin, Chen, Jueqi, Xu, Hui, Liu, Siqi, Jiang, Qiu-Xing, Halfmann, Randal, Chen, Zhijian J.

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Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP von Shang, Guijun, Zhang, Conggang, Chen, Zhijian J., Bai, Xiao-chen, Zhang, Xuewu

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Old dogs, new trick: classic cancer therapies activate cGAS von Yum, Seoyun, Li, Minghao, Chen, Zhijian J.

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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway von Gui, Xiang, Yang, Hui, Li, Tuo, Tan, Xiaojun, Shi, Peiqing, Li, Minghao, Du, Fenghe, Chen, Zhijian J.

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STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway von Tanaka, Yasuo, Chen, Zhijian J

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cGAS is essential for the antitumor effect of immune checkpoint blockade von Wang, Hua, Hu, Shuiqing, Chen, Xiang, Shi, Heping, Chen, Chuo, Sun, Lijun, Chen, Zhijian J.

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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors von Deng, Liufu, Liang, Hua, Xu, Meng, Yang, Xuanming, Burnette, Byron, Arina, Ainhoa, Li, Xiao-Dong, Mauceri, Helena, Beckett, Michael, Darga, Thomas, Huang, Xiaona, Gajewski, Thomas F., Chen, Zhijian J., Fu, Yang-Xin, Weichselbaum, Ralph R.

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Direct, Noncatalytic Mechanism of IKK Inhibition by A20 von Skaug, Brian, Chen, Jueqi, Du, Fenghe, He, Jin, Ma, Averil, Chen, Zhijian J.

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