GABC: A comprehensive resource and Genome Atlas for Breast Cancer von Zhang, Yunpeng, Wang, Peng, Li, Xin, Ning, Shangwei, Li, Xia, Cao, Yan, Chen, Steven Xi

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Interpreting pathways to discover cancer driver genes with Moonlight von Colaprico, Antonio, Olsen, Catharina, Bailey, Matthew H., Odom, Gabriel J., Terkelsen, Thilde, Silva, Tiago C., Olsen, André V., Cantini, Laura, Zinovyev, Andrei, Barillot, Emmanuel, Noushmehr, Houtan, Bertoli, Gloria, Castiglioni, Isabella, Cava, Claudia, Bontempi, Gianluca, Chen, Xi Steven, Papaleo, Elena

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Activation of STAT3 signaling is mediated by TFF1 silencing in gastric neoplasia von Soutto, Mohammed, Chen, Zheng, Bhat, Ajaz A., Wang, Lihong, Zhu, Shoumin, Gomaa, Ahmed, Bates, Andreia, Bhat, Nadeem S., Peng, Dunfa, Belkhiri, Abbes, Piazuelo, M. Blanca, Washington, M. Kay, Steven, Xi Chen, Peek, Richard, El-Rifai, Wael

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Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer von Samaranayake, Govindi J., Troccoli, Clara I., Huynh, Mai, Lyles, Rolando D. Z., Kage, Karen, Win, Andrew, Lakshmanan, Vishalakshi, Kwon, Deukwoo, Ban, Yuguang, Chen, Steven Xi, Zarco, Enrique Rodriguez, Jorda, Merce, Burnstein, Kerry L., Rai, Priyamvada

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Fibroblast growth factor receptor-4 mediates activation of Nuclear Factor Erythroid 2-Related Factor-2 in gastric tumorigenesis von Soutto, Mohammed, Zhang, Xing, Bhat, Nadeem, Chen, Zheng, Zhu, Shoumin, Maacha, Selma, Genoula, Melanie, El-Gazzaz, Omar, Peng, Dunfa, Lu, Heng, McDonald, Oliver G., Chen, Xi Steven, Cao, Longlong, Xu, Zekuan, El-Rifai, Wael

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Comprehensive Characterization of Somatic Mutations Impacting lncRNA Expression for Pan-Cancer von Gao, Yue, Li, Xin, Zhi, Hui, Zhang, Yunpeng, Wang, Peng, Wang, Yanxia, Shang, Shipeng, Fang, Ying, Shen, Weitao, Ning, Shangwei, Chen, Steven Xi, Li, Xia

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Obstacles to successful treatment of hepatitis C in uninsured patients from a minority population von DeBose-Scarlett, Alexandra, Balise, Raymond, Kwon, Deukwoo, Vadaparampil, Susan, Chen, Steven Xi, Schiff, Eugene R, Ayala, Gladys Patricia, Thomas, Emmanuel

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Mutant IDH1 Depletion Downregulates Integrins and Impairs Chondrosarcoma Growth von Li, Luyuan, Hu, Xiaoyu, Eid, Josiane E., Rosenberg, Andrew E., Wilky, Breelyn A., Ban, Yuguang, Sun, Xiaodian, Galoian, Karina, DeSalvo, Joanna, Yue, Jinbo, Chen, Xi Steven, Blonska, Marzenna, Trent, Jonathan C.

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Systemically Identifying Triple-Negative Breast Cancer Subtype-Specific Prognosis Signatures, Based on Single-Cell RNA-Seq Data von Xing, Kaiyuan, Zhang, Bo, Wang, Zixuan, Zhang, Yanru, Chai, Tengyue, Geng, Jingkai, Qin, Xuexue, Chen, Xi Steven, Zhang, Xinxin, Xu, Chaohan

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A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients von Gowrikumar, Saiprasad, Primeaux, Mark, Pravoverov, Kristina, Wu, Chao, Szeglin, Bryan C., Sauve, Charles-Etienne Gabriel, Thapa, Ishwor, Bastola, Dhundy, Chen, Xi Steven, Smith, J. Joshua, Singh, Amar B., Dhawan, Punita

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Downregulation of SOCS1 increases interferon-induced ISGylation during differentiation of induced-pluripotent stem cells to hepatocytes von Edwards, Jasmine S, Delabat, Stephanie A, Badilla, Alejandro D, DiCaprio, Robert C, Hyun, Jinhee, Burgess, Robert A, Silva, Tiago, Dykxhoorn, Derek M, Chen, Steven Xi, Wang, Lily, Ishida, Yuji, Saito, Takeshi, Thomas, Emmanuel

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NFκB in Pancreatic Stellate Cells Reduces Infiltration of Tumors by Cytotoxic T Cells and Killing of Cancer Cells, via Up-regulation of CXCL12 von Garg, Bharti, Giri, Bhuwan, Modi, Shrey, Sethi, Vrishketan, Castro, Iris, Umland, Oliver, Ban, Yuguang, Lavania, Shweta, Dawra, Rajinder, Banerjee, Sulagna, Vickers, Selwyn, Merchant, Nipun B., Chen, Steven Xi, Gilboa, Eli, Ramakrishnan, Sundaram, Saluja, Ashok, Dudeja, Vikas

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1291 CHRONIC GASTROESOPHAGEAL REFLUX PROMOTES CHEMORESISTANCE IN ESOPHAGEAL ADENOCARCINOMA THROUGH APE1-REDOX-DEPENDENT PRDX2 ACTIVATION AND FERROPTOSIS INHIBITION von CHEN, LEI, Lu, Heng, Ballout, Farah, Peng, Dunfa, Chen, Zheng, Que, Jianwen, Giordano, Silvia, Chen, Steven Xi, McDonald, Oliver G., Zaika, Alexander, El-Rifai, Wael

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LnCeVar: a comprehensive database of genomic variations that disturb ceRNA network regulation von Wang, Peng, Li, Xin, Gao, Yue, Guo, Qiuyan, Ning, Shangwei, Zhang, Yunpeng, Shang, Shipeng, Wang, Junwei, Wang, Yanxia, Zhi, Hui, Fang, Ying, Shen, Weitao, Zhang, Guangmei, Chen, Steven Xi, Li, Xia

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A workflow to study mechanistic indicators for driver gene prediction with Moonlight von Nourbakhsh, Mona, Saksager, Astrid, Tom, Nikola, Chen, Xi Steven, Colaprico, Antonio, Olsen, Catharina, Tiberti, Matteo, Papaleo, Elena

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Deep functional immunophenotyping predicts risk of cytomegalovirus reactivation after hematopoietic cell transplantation von Camargo, Jose F., Wieder, Eric D., Kimble, Erik, Benjamin, Cara L., Kolonias, Despina S., Kwon, Deukwoo, Chen, Xi Steven, Komanduri, Krishna V.

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Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure von Patel, Rutulkumar, Zhang, Luchang, Desai, Amar, Hoenerhoff, Mark J., Kennedy, Lucy H., Radivoyevitch, Tomas, Ban, Yuguang, Chen, Xi Steven, Gerson, Stanton L., Welford, Scott M.

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Abstract B032: Inappropriate AR reactivation-induced redox stress as a novel therapeutic target in castration-resistant prostate cancer von Samaranayake, Govindi J., Troccoli, Clara I., Huynh, Mai Q., Lyles, Rolando D.Z., Kwon, Deukwoo, Ban, Yuguang, Chen, Steven Xi, Jorda, Merce, Burnstein, Kerry, Rai, Priyamvada

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Abstract 1342: Loss of claudin-3 expression induces IL6/gp130/Stat3 signaling to promote colon cancer malignancy von Ahmad, Rizwan, kumar, Balawant, Chen, Zhimin, Chen, Steven(Xi), Muller, Dominik, Lele, Subodh M., Washington, Mary Kay, Batra, Surinder K., Dhawan, Punita, Singh, Amar B.

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The mechanism of cancer drug addiction in ALK-positive T-Cell lymphoma von Rajan, Soumya S., Amin, Amit Dipak, Li, Lingxiao, Rolland, Delphine C., Li, Haiquan, Kwon, Deukwoo, Kweh, Mercedes F., Arumov, Artavazd, Roberts, Evan R., Yan, Aimin, Basrur, Venkatesha, Elenitoba-Johnson, Kojo S. J., Chen, Xi Steven, Puvvada, Soham D., Lussier, Yves A., Bilbao, Daniel, Lim, Megan S., Schatz, Jonathan H.

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