A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function von Liu, Yaobin, Huang, Xiangao, He, Xian, Zhou, Yanqing, Jiang, Xiaogang, Chen‐Kiang, Selina, Jaffrey, Samie R., Xu, Guoqiang

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Phase 2 trial of the histone deacetylase inhibitor romidepsin for the treatment of refractory multiple myeloma von Niesvizky, Ruben, Ely, Scott, Mark, Tomer, Aggarwal, Sangeeta, Gabrilove, Janice L, Wright, John J., Chen‐Kiang, Selina, Sparano, Joseph A

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Selenite Inhibits Notch Signaling in Cells and Mice von Powers, Michael, Liu, Liu, Deemer, Dane, Chen, Selina, Scholl, Aaron, Yoshinaga, Masafumi, Liu, Zijuan

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A phase 1 trial of ibrutinib plus palbociclib in previously treated mantle cell lymphoma von Martin, Peter, Bartlett, Nancy L., Blum, Kristie A., Park, Steven, Maddocks, Kami, Ruan, Jia, Ridling, LeAnn, Dittus, Christopher, Chen, Zhengming, Huang, Xiangao, Inghirami, Giorgio, DiLiberto, Maurizio, Chen-Kiang, Selina, Leonard, John P.

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Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation von Alinari, Lapo, Mahasenan, Kiran V., Yan, Fengting, Karkhanis, Vrajesh, Chung, Ji-Hyun, Smith, Emily M., Quinion, Carl, Smith, Porsha L., Kim, Lisa, Patton, John T., Lapalombella, Rosa, Yu, Bo, Wu, Yun, Roy, Satavisha, De Leo, Alessandra, Pileri, Stefano, Agostinelli, Claudio, Ayers, Leona, Bradner, James E., Chen-Kiang, Selina, Elemento, Olivier, Motiwala, Tasneem, Majumder, Sarmila, Byrd, John C., Jacob, Samson, Sif, Said, Li, Chenglong, Baiocchi, Robert A.

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Outcome of Deferred Initial Therapy in Mantle-Cell Lymphoma von MARTIN, Peter, CHADBURN, Amy, MELNICK, Ari, KNOWLES, Daniel M, CHEN-KIANG, Selina, COLEMAN, Morton, LEONARD, John P, CHRISTOS, Paul, WEIL, Karen, FURMAN, Richard R, JIA RUAN, ELSTROM, Rebecca, NIESVIZKY, Ruben, ELY, Scott, DILIBERTO, Maurizio

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A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas von Jang, Ja-Young, Hwang, Inah, Pan, Heng, Yao, Jun, Alinari, Lapo, Imada, Eddie, Zanettini, Claudio, Kluk, Michael J, Wang, Yizhe, Lee, Yunkyoung, Lin, Hua V, Huang, Xiangao, Di Liberto, Maurizio, Chen, Zhengming, Ballman, Karla V, Cantley, Lewis C, Marchionni, Luigi, Inghirami, Giorgio, Elemento, Olivier, Baiocchi, Robert A, Chen-Kiang, Selina, Belvedere, Sandro, Zheng, Hongwu, Paik, Jihye

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Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter’s transformation von Hing, Zachary A., Walker, Janek S., Whipp, Ethan C., Brinton, Lindsey, Cannon, Matthew, Zhang, Pu, Sher, Steven, Cempre, Casey B., Brown, Fiona, Smith, Porsha L., Agostinelli, Claudio, Pileri, Stefano A., Skinner, Jordan N., Williams, Katie, Phillips, Hannah, Shaffer, Jami, Beaver, Larry P., Pan, Alexander, Shin, Kyle, Gregory, Charles T., Ozer, Gulcin H., Yilmaz, Selen A., Harrington, Bonnie K., Lehman, Amy M., Yu, Lianbo, Coppola, Vincenzo, Yan, Pearlly, Scherle, Peggy, Wang, Min, Pitis, Philip, Xu, Chaoyi, Vaddi, Kris, Chen-Kiang, Selina, Woyach, Jennifer, Blachly, James S., Alinari, Lapo, Yang, Yiping, Byrd, John C., Baiocchi, Robert A., Blaser, Bradley W., Lapalombella, Rosa

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A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model von Menu, Eline, Garcia, Josefina, Huang, Xiangao, Di Liberto, Maurizio, Toogood, Peter L, Chen, Isan, Vanderkerken, Karin, Chen-Kiang, Selina

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Cell-cycle control of plasma cell differentiation and tumorigenesis von Chen-Kiang, Selina

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Clarithromycin (Biaxin)‐lenalidomide‐low‐dose dexamethasone (BiRd) versus lenalidomide‐low‐dose dexamethasone (Rd) for newly diagnosed myeloma von Gay, Francesca, Rajkumar, S. Vincent, Coleman, Morton, Kumar, Shaji, Mark, Tomer, Dispenzieri, Angela, Pearse, Roger, Gertz, Morie A., Leonard, John, Lacy, Martha Q., Chen‐Kiang, Selina, Roy, Vivek, Jayabalan, David S., Lust, John A., Witzig, Thomas E., Fonseca, Rafael, Kyle, Robert A., Greipp, Philip R., Stewart, A. Keith, Niesvizky, Ruben

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Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma von Leonard, John P., LaCasce, Ann S., Smith, Mitchell R., Noy, Ariela, Chirieac, Lucian R., Rodig, Scott J., Yu, Jian Q., Vallabhajosula, Shankar, Schoder, Heiko, English, Patricia, Neuberg, Donna S., Martin, Peter, Millenson, Michael M., Ely, Scott A., Courtney, Rachel, Shaik, Naveed, Wilner, Keith D., Randolph, Sophia, Van den Abbeele, Annick D., Chen-Kiang, Selina Y., Yap, Jeffrey T., Shapiro, Geoffrey I.

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MAGE-A Inhibits Apoptosis in Proliferating Myeloma Cells through Repression of Bax and Maintenance of Survivin von NARDIELLO, Tricia, JUNGBLUTH, Achim A, PEARSE, Roger, COLEMAN, Morton, JAYABALAN, David S, BHARDWAJ, Nina, OLD, Lloyd J, CHEN-KIANG, Selina, HEARN JAY CHO, MEI, Anna, DILIBERTO, Maurizio, XIANGAO HUANG, DABROWSKI, Ania, ANDRADE, Valéria C. C, WASSERSTRUM, Rebecca, ELY, Scott, NIESVIZKY, Ruben

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A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6 von BAUGHN, Linda B, DI LIBERTO, Maurizio, CHEN-KIANG, Selina, KAIDA WU, TOOGOOD, Peter L, LOUIE, Tracey, GOTTSCHALK, Rachel, NIESVIZKY, Ruben, CHO, Hearn, ELY, Scott, MOORE, Malcolm A. S

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BiRD (Biaxin [clarithromycin]/Revlimid [lenalidomide]/dexamethasone) combination therapy results in high complete- and overall-response rates in treatment-naive symptomatic multipl... von Niesvizky, Ruben, Jayabalan, David S., Christos, Paul J., Furst, Jessica R., Naib, Tara, Ely, Scott, Jalbrzikowski, Jessica, Pearse, Roger N., Zafar, Faiza, Pekle, Karen, LaRow, April, Lent, Richard, Mark, Tomer, Cho, Hearn J., Shore, Tsiporah, Tepler, Jeffrey, Harpel, John, Schuster, Michael W., Mathew, Susan, Leonard, John P., Mazumdar, Madhu, Chen-Kiang, Selina, Coleman, Morton

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The presence of F cells with a fetal phenotype in adults with hemoglobinopathies limits the utility of flow cytometry for quantitation of fetomaternal hemorrhage von Othman, Jad, Orellana, Daniel, Chen, Lin Selina, Russell, Megan, Khoo, Teh‐Liane

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Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response von Do, R K, Hatada, E, Lee, H, Tourigny, M R, Hilbert, D, Chen-Kiang, S

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Deletions of CDKN2C in Multiple Myeloma: Biological and Clinical Implications von LEONE, Paola E, WALKER, Brian A, GONZALEZ, David, ROSS, Fiona M, CHEN-KIANG, Selina, DAVIES, Faith E, MORGAN, Gareth J, JENNER, Matthew W, CHIECCHIO, Laura, DAGRADA, Gianpaolo, PROTHEROE, Rebecca K. M, JOHNSON, David C, DICKENS, Nicholas J, BRITO, Jose Luis, ELSE, Monica

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A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells von Hanel, Walter, Lata, Pushpa, Youssef, Youssef, Tran, Ha, Tsyba, Liudmyla, Sehgal, Lalit, Blaser, Bradley W, Huszar, Dennis, Helmig-Mason, JoBeth, Zhang, Liwen, Schrock, Morgan S, Summers, Matthew K, Chan, Wing Keung, Prouty, Alexander, Mundy-Bosse, Bethany L, Chen-Kiang, Selina, Danilov, Alexey V, Maddocks, Kami, Baiocchi, Robert A, Alinari, Lapo

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Overcoming the response plateau in multiple myeloma: a novel bortezomib-based strategy for secondary induction and high-yield CD34+ stem cell mobilization von Niesvizky, Ruben, Mark, Tomer M, Ward, Maureen, Jayabalan, David S, Pearse, Roger N, Manco, Megan, Stern, Jessica, Christos, Paul J, Mathews, Lena, Shore, Tsiporah B, Zafar, Faiza, Pekle, Karen, Xiang, Zhaoying, Ely, Scott, Skerret, Donna, Chen-Kiang, Selina, Coleman, Morton, Lane, Maureen E

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