RBPJ-dependent Notch signaling initiates the T cell program in a subset of thymus-seeding progenitors von Chen, Edward L. Y., Thompson, Patrycja K., Zúñiga-Pflücker, Juan Carlos

Volltext

NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development von Li, Jie, Gordon, Julie, Chen, Edward L. Y., Xiao, Shiyun, Wu, Luying, Zuniga-Pflucker, Juan Carlos, Manley, Nancy R.

Volltext

In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer von Dervovic, Dzana, Malik, Ahmad A., Chen, Edward L. Y., Narimatsu, Masahiro, Adler, Nina, Afiuni-Zadeh, Somaieh, Krenbek, Dagmar, Martinez, Sebastien, Tsai, Ricky, Boucher, Jonathan, Berman, Jacob M., Teng, Katie, Ayyaz, Arshad, Lü, YiQing, Mbamalu, Geraldine, Loganathan, Sampath K., Lee, Jongbok, Zhang, Li, Guidos, Cynthia, Wrana, Jeffrey, Valipour, Arschang, Roux, Philippe P., Reimand, Jüri, Jackson, Hartland W., Schramek, Daniel

Volltext

HEB is required for the specification of fetal IL-17-producing γδ T cells von In, Tracy S. H., Trotman-Grant, Ashton, Fahl, Shawn, Chen, Edward L. Y., Zarin, Payam, Moore, Amanda J., Wiest, David L., Zúñiga-Pflücker, Juan Carlos, Anderson, Michele K.

Volltext

Realization of the T Lineage Program Involves GATA-3 Induction of Bcl11b and Repression of Cdkn2b Expression von Thompson, Patrycja K, Chen, Edward L Y, de Pooter, Renée F, Frelin, Catherine, Vogel, Walter K, Lee, Christina R, Venables, Thomas, Shah, Divya K, Iscove, Norman N, Leid, Mark, Anderson, Michele K, Zúñiga-Pflücker, Juan Carlos

Volltext

Realization of the T-lineage program involves GATA-3 induction of Bcl11b and repression of Cdkn2b expression1 von Thompson, Patrycja K., Chen, Edward L.Y., de Pooter, Renée F., Frelin, Catherine, Vogel, Walter K., Lee, Christina R., Venables, Thomas, Shah, Divya K., Iscove, Norman N., Leid, Mark, Anderson, Michele K., Zúñiga-Pflücker, Juan Carlos

Volltext

Single-cell atlas of the human brain vasculature across development, adulthood and disease von Waelchli, Thomas, Ghobrial, Moheb, Schwab, Marc, Takada, Shigeki, Zhong, Hang, Suntharalingham, Samuel, Vetiska, Sandra, Gonzalez, Dayme Rodrigues, Wu, Ruilin, Rehrauer, Hubert, Dinesh, Anuroopa, Yu, Kai, Chen, Edward L.Y, Bisschop, Jeroen, Farnhammer, Fiona, Mansur, Ann, Kalucka, Joanna, Tirosh, Itay, Regli, Luca, Schaller, Karl, Frei, Karl, Ketela, Troy, Bernstein, Mark, Kongkham, Paul, Carmeliet, Peter, Valiante, Taufik, Dirks, Peter B, Suva, Mario L, Zadeh, Gelareh, Tabar, Viviane, Schlapbach, Ralph, Jackson, Hartland W, De Bock, Katrien, Fish, Jason E, Monnier, Philippe P, Bader, Gary D, Radovanovic, Ivan

Volltext

Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo von Chen, Edward L.Y., Lee, Christina R., Thompson, Patrycja K., Wiest, David L., Anderson, Michele K., Zúñiga-Pflücker, Juan Carlos

Volltext

Peroxisome Proliferator-Activated Receptor-δ Supports the Metabolic Requirements of Cell Growth in TCRβ-Selected Thymocytes and Peripheral CD4 + T Cells von Zhao, Fei Linda, Ahn, Jeeyoon Jennifer, Chen, Edward L Y, Yi, Tae Joon, Stickle, Natalie H, Spaner, David, Zúñiga-Pflücker, Juan Carlos, Dunn, Shannon E

Volltext

Integration of T‐cell receptor, Notch and cytokine signals programs mouse γδ T‐cell effector differentiation von Zarin, Payam, In, Tracy SH, Chen, Edward LY, Singh, Jastaranpreet, Wong, Gladys W, Mohtashami, Mahmood, Wiest, David L, Anderson, Michele K, Zúñiga‐Pflücker, Juan Carlos

Volltext

Gamma delta T-cell differentiation and effector function programming, TCR signal strength, when and how much? von Zarin, Payam, Chen, Edward L.Y., In, Tracy S.H., Anderson, Michele K., Zúñiga-Pflücker, Juan Carlos

Volltext

Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of HBeAg-positive chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferio... von Chan, Henry L Y, Fung, Scott, Seto, Wai Kay, Chuang, Wan-Long, Chen, Chi-Yi, Kim, Hyung Joon, Hui, Aric Josun, Janssen, Harry L A, Chowdhury, Abhijit, Tsang, Tak Yin Owen, Mehta, Rajiv, Gane, Edward, Flaherty, John F, Massetto, Benedetta, Gaggar, Anuj, Kitrinos, Kathryn M, Lin, Lanjia, Subramanian, G Mani, McHutchison, John G, Lim, Young-Suk, Acharya, Subrat K, Agarwal, Kosh

Volltext

Switching from tenofovir disoproxil fumarate to tenofovir alafenamide in virologically suppressed patients with chronic hepatitis B: a randomised, double-blind, phase 3, multicentr... von Lampertico, Pietro, Buti, Maria, Fung, Scott, Ahn, Sang Hoon, Chuang, Wan-Long, Tak, Won Young, Ramji, Alnoor, Chen, Chi-Yi, Tam, Edward, Bae, Ho, Ma, Xiaoli, Flaherty, John F, Gaggar, Anuj, Lau, Audrey, Liu, Yang, Wu, George, Suri, Vithika, Tan, Susanna K, Subramanian, G Mani, Trinh, Huy, Yoon, Seung-Kew, Agarwal, Kosh, Lim, Young-Suk, Chan, Henry L Y

Volltext