H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis von Harutyunyan, Ashot S., Krug, Brian, Chen, Haifen, Papillon-Cavanagh, Simon, Zeinieh, Michele, De Jay, Nicolas, Deshmukh, Shriya, Chen, Carol C. L., Belle, Jad, Mikael, Leonie G., Marchione, Dylan M., Li, Rui, Nikbakht, Hamid, Hu, Bo, Cagnone, Gael, Cheung, Warren A., Mohammadnia, Abdulshakour, Bechet, Denise, Faury, Damien, McConechy, Melissa K, Pathania, Manav, Jain, Siddhant U., Ellezam, Benjamin, Weil, Alexander G., Montpetit, Alexandre, Salomoni, Paolo, Pastinen, Tomi, Lu, Chao, Lewis, Peter W., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Majewski, Jacek

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Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness von Boileau, Meaghan, Shirinian, Margret, Gayden, Tenzin, Harutyunyan, Ashot S., Chen, Carol C. L., Mikael, Leonie G., Duncan, Heather M., Neumann, Andrea L., Arreba-Tutusaus, Patricia, De Jay, Nicolas, Zeinieh, Michele, Rossokhata, Katya, Zhang, Yelu, Nikbakht, Hamid, Mouawad, Carine, Massoud, Radwan, Frey, Felice, Nasr, Rihab, El Cheikh, Jean, El Sabban, Marwan, Kleinman, Claudia L., Mahfouz, Rami, Minden, Mark D., Jabado, Nada, Bazarbachi, Ali, Eppert, Kolja

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H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2 von Chen, Carol C L, Goyal, Preeti, Karimi, Mohammad M, Abildgaard, Marie H, Kimura, Hiroshi, Lorincz, Matthew C

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SMARCA4 vulnerability in H3K27M midline glioma: A silver bullet for a lethal disease von Chen, Carol C.L., Andrade, Augusto Faria, Jabado, Nada

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Oncohistones in brain tumors: the soil and seed von Andrade, Augusto Faria, Chen, Carol C L, Jabado, Nada

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Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas von Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, Sima, Koncar, Robert F., Agnihotri, Sameer, Faury, Damien, Ellezam, Benjamin, Weil, Alexander G., Ursini-Siegel, Josie, De Carvalho, Daniel D., Dirks, Peter B., Lewis, Peter W., Salomoni, Paolo, Lupien, Mathieu, Arrowsmith, Cheryl, Lasko, Paul F., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Mack, Stephen C.

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Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration von Khazaei, Sima, Chen, Carol C.L., Andrade, Augusto Faria, Kabir, Nisha, Azarafshar, Pariya, Morcos, Shahir M., França, Josiane Alves, Lopes, Mariana, Lund, Peder J., Danieau, Geoffroy, Worme, Samantha, Adnani, Lata, Nzirorera, Nadine, Chen, Xiao, Yogarajah, Gayathri, Russo, Caterina, Zeinieh, Michele, Wong, Cassandra J., Bryant, Laura, Hébert, Steven, Tong, Bethany, Sihota, Tianna S., Faury, Damien, Puligandla, Evan, Jawhar, Wajih, Sandy, Veronica, Cowan, Mitra, Nakada, Emily M., Jerome-Majewska, Loydie A., Ellezam, Benjamin, Gomes, Carolina Cavalieri, Denecke, Jonas, Lessel, Davor, McDonald, Marie T., Pizoli, Carolyn E., Taylor, Kathryn, Cocanougher, Benjamin T., Bhoj, Elizabeth J., Gingras, Anne-Claude, Garcia, Benjamin A., Lu, Chao, Campos, Eric I., Kleinman, Claudia L., Garzia, Livia, Jabado, Nada

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Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks von Chaouch, Amel, Berlandi, Johannes, Chen, Carol C.L., Frey, Felice, Badini, Shireen, Harutyunyan, Ashot S., Chen, Xiao, Krug, Brian, Hébert, Steven, Jeibmann, Astrid, Lu, Chao, Kleinman, Claudia L., Hasselblatt, Martin, Lasko, Paul, Shirinian, Margret, Jabado, Nada

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TULIPs decorate the three-dimensional genome of PFA ependymoma von Johnston, Michael J., Lee, John J.Y., Hu, Bo, Nikolic, Ana, Hasheminasabgorji, Elham, Baguette, Audrey, Paik, Seungil, Chen, Haifen, Kumar, Sachin, Chen, Carol C.L., Jessa, Selin, Balin, Polina, Fong, Vernon, Zwaig, Melissa, Michealraj, Kulandaimanuvel Antony, Chen, Xun, Zhang, Yanlin, Varadharajan, Srinidhi, Billon, Pierre, Juretic, Nikoleta, Daniels, Craig, Rao, Amulya Nageswara, Giannini, Caterina, Thompson, Eric M., Garami, Miklos, Hauser, Peter, Pocza, Timea, Ra, Young Shin, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Lee, Ji Yeoun, Grajkowska, Wieslawa, Perek-Polnik, Marta, Agnihotri, Sameer, Mack, Stephen, Ellezam, Benjamin, Weil, Alex, Rich, Jeremy, Bourque, Guillaume, Chan, Jennifer A., Yong, V. Wee, Lupien, Mathieu, Ragoussis, Jiannis, Kleinman, Claudia, Majewski, Jacek, Blanchette, Mathieu, Jabado, Nada, Taylor, Michael D., Gallo, Marco

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Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas von Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, Sima, Koncar, Robert F., Agnihotri, Sameer, Faury, Damien, Ellezam, Benjamin, Weil, Alexander G., Ursini-Siegel, Josie, De Carvalho, Daniel D., Dirks, Peter B., Lewis, Peter W., Salomoni, Paolo, Lupien, Mathieu, Arrowsmith, Cheryl, Lasko, Paul F., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Mack, Stephen C.

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Meet the authors: Amel Chaouch, Carol CL Chen, and Margret Shirinian von Chaouch, Amel, Chen, Carol C. L., Shirinian, Margret

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Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis von Chen, Carol C.L., Deshmukh, Shriya, Jessa, Selin, Hadjadj, Djihad, Lisi, Véronique, Andrade, Augusto Faria, Faury, Damien, Jawhar, Wajih, Dali, Rola, Suzuki, Hiromichi, Pathania, Manav, A, Deli, Dubois, Frank, Woodward, Eleanor, Hébert, Steven, Coutelier, Marie, Karamchandani, Jason, Albrecht, Steffen, Brandner, Sebastian, De Jay, Nicolas, Gayden, Tenzin, Bajic, Andrea, Harutyunyan, Ashot S., Marchione, Dylan M., Mikael, Leonie G., Juretic, Nikoleta, Zeinieh, Michele, Russo, Caterina, Maestro, Nicola, Bassenden, Angelia V., Hauser, Peter, Virga, József, Bognar, Laszlo, Klekner, Almos, Zapotocky, Michal, Vicha, Ales, Krskova, Lenka, Vanova, Katerina, Zamecnik, Josef, Sumerauer, David, Ekert, Paul G., Ziegler, David S., Ellezam, Benjamin, Filbin, Mariella G., Blanchette, Mathieu, Hansford, Jordan R., Khuong-Quang, Dong-Anh, Berghuis, Albert M., Weil, Alexander G., Garcia, Benjamin A., Garzia, Livia, Mack, Stephen C., Beroukhim, Rameen, Ligon, Keith L., Taylor, Michael D., Bandopadhayay, Pratiti, Kramm, Christoph, Pfister, Stefan M., Korshunov, Andrey, Sturm, Dominik, Jones, David T.W., Salomoni, Paolo, Kleinman, Claudia L., Jabado, Nada

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Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of chromatin marks von Chaouch, Amel, Berlandi, Johannes, Chen, Carol C. L., Frey, Felice, Badini, Shireen, Harutyunyan, Ashot S., Chen, Xiao, Krug, Brian, Hebert, Steven, Jeibmann, Astrid, Lu, Chao, Kleinman, Claudia L., Hasselblatt, Martin, Lasko, Paul, Shirinian, Margret, Jabado, Nada

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H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone von Khazaei, Sima, De Jay, Nicolas, Deshmukh, Shriya, Hendrikse, Liam D., Jawhar, Wajih, Chen, Carol C. L., Mikael, Leonie G., Faury, Damien, Marchione, Dylan M., Lanoix, Joel, Bonneil, Eric, Ishii, Takeaki, Jain, Siddhant U., Rossokhata, Kateryna, Sihota, Tianna S., Eveleigh, Robert, Lisi, Veronique, Harutyunyan, Ashot S., Jung, Sungmi, Karamchandani, Jason, Dickson, Brendan C., Turcotte, Robert, Wunder, Jay S., Thibault, Pierre, Lewis, Peter W., Garcia, Benjamin A., Mack, Stephen C., Taylor, Michael D., Garzia, Livia, Kleinman, Claudia L., Jabado, Nada

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ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation von Stone, Erica L, Pepper, Marion, Katayama, Carol D, Kerdiles, Yann M, Lai, Chen-Yen, Emslie, Elizabeth, Lin, Yin C, Yang, Edward, Goldrath, Ananda W, Li, Ming O, Cantrell, Doreen A, Hedrick, Stephen M

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The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controll... von Baigent, Colin, Prof, Landray, Martin J, FRCP, Reith, Christina, MRCP, Emberson, Jonathan, PhD, Wheeler, David C, FRCP, Tomson, Charles, DM, Wanner, Christoph, Prof, Krane, Vera, MD, Cass, Alan, Prof, Craig, Jonathan, Prof, Neal, Bruce, Prof, Jiang, Lixin, MD, Hooi, Lai Seong, FRCP, Levin, Adeera, Prof, Agodoa, Lawrence, Prof, Gaziano, Mike, Prof, Kasiske, Bertram, Prof, Walker, Robert, Prof, Massy, Ziad A, Prof, Feldt-Rasmussen, Bo, Prof, Krairittichai, Udom, MD, Ophascharoensuk, Vuddidhej, MD, Fellström, Bengt, Prof, Holdaas, Hallvard, MD, Tesar, Vladimir, Prof, Wiecek, Andrzej, Prof, Grobbee, Diederick, Prof, de Zeeuw, Dick, Prof, Grönhagen-Riska, Carola, Prof, Dasgupta, Tanaji, MRCP, Lewis, David, MRCP, Herrington, William, MRCP, Mafham, Marion, MD, Majoni, William, FRACP, Wallendszus, Karl, MSc, Grimm, Richard, Prof, Pedersen, Terje, Prof, Tobert, Jonathan, PhD, Armitage, Jane, Prof, Baxter, Alex, BA, Bray, Christopher, PhD, Chen, Yiping, DPhil, Chen, Zhengming, Prof, Hill, Michael, DPhil, Knott, Carol, MSc, Parish, Sarah, DPhil, Simpson, David, Sleight, Peter, Prof, Young, Alan, DPhil, Collins, Rory, Prof

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Sustained release of endothelial progenitor cell-derived extracellular vesicles from shear-thinning hydrogels improves angiogenesis and promotes function after myocardial infarctio... von Chen, Carol W, Wang, Leo L, Zaman, Samir, Gordon, Jon, Arisi, Maria F, Venkataraman, Chantel M, Chung, Jennifer J, Hung, George, Gaffey, Ann C, Spruce, Lynn A, Fazelinia, Hossein, Gorman, Robert C, Seeholzer, Steven H, Burdick, Jason A, Atluri, Pavan

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High prevalence of myopia in children and their parents in Hong Kong Chinese Population: the Hong Kong Children Eye Study von Yam, Jason C., Tang, Shu Min, Kam, Ka Wai, Chen, Li Jia, Yu, Marco, Law, Antony K., Yip, Benjamin H., Wang, Yu Meng, Cheung, Carol Y. L., Ng, Danny S.C., Young, Alvin L., Tham, Clement C., Pang, Chi Pui

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Brown Adipose Reporting Criteria in Imaging STudies (BARCIST 1.0): Recommendations for Standardized FDG-PET/CT Experiments in Humans von Chen, Kong Y., Cypess, Aaron M., Laughlin, Maren R., Haft, Carol R., Hu, Houchun Harry, Bredella, Miriam A., Enerbäck, Sven, Kinahan, Paul E., Lichtenbelt, Wouter van Marken, Lin, Frank I., Sunderland, John J., Virtanen, Kirsi A., Wahl, Richard L.

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Myocarditis in Patients Treated With Immune Checkpoint Inhibitors von Mahmood, Syed S., Fradley, Michael G., Cohen, Justine V., Nohria, Anju, Reynolds, Kerry L., Heinzerling, Lucie M., Sullivan, Ryan J., Damrongwatanasuk, Rongras, Chen, Carol L., Gupta, Dipti, Kirchberger, Michael C., Awadalla, Magid, Hassan, Malek Z.O., Moslehi, Javid J., Shah, Sachin P., Ganatra, Sarju, Thavendiranathan, Paaladinesh, Lawrence, Donald P., Groarke, John D., Neilan, Tomas G.

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