Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity von Lai, Junyun, Mardiana, Sherly, House, Imran G., Sek, Kevin, Henderson, Melissa A., Giuffrida, Lauren, Chen, Amanda X. Y., Todd, Kirsten L., Petley, Emma V., Chan, Jack D., Carrington, Emma M., Lew, Andrew M., Solomon, Benjamin J., Trapani, Joseph A., Kedzierska, Katherine, Evrard, Maximilien, Vervoort, Stephin J., Waithman, Jason, Darcy, Phillip K., Beavis, Paul A.

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CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy von Giuffrida, Lauren, Sek, Kevin, Henderson, Melissa A., Lai, Junyun, Chen, Amanda X. Y., Meyran, Deborah, Todd, Kirsten L., Petley, Emma V., Mardiana, Sherly, Mølck, Christina, Stewart, Gregory D., Solomon, Benjamin J., Parish, Ian A., Neeson, Paul J., Harrison, Simon J., Kats, Lev M., House, Imran G., Darcy, Phillip K., Beavis, Paul A.

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MAIT cells regulate NK cell-mediated tumor immunity von Petley, Emma V., Koay, Hui-Fern, Henderson, Melissa A., Sek, Kevin, Todd, Kirsten L., Keam, Simon P., Lai, Junyun, House, Imran G., Li, Jasmine, Zethoven, Magnus, Chen, Amanda X. Y., Oliver, Amanda J., Michie, Jessica, Freeman, Andrew J., Giuffrida, Lauren, Chan, Jack D., Pizzolla, Angela, Mak, Jeffrey Y. W., McCulloch, Timothy R., Souza-Fonseca-Guimaraes, Fernando, Kearney, Conor J., Millen, Rosemary, Ramsay, Robert G., Huntington, Nicholas D., McCluskey, James, Oliaro, Jane, Fairlie, David P., Neeson, Paul J., Godfrey, Dale I., Beavis, Paul A., Darcy, Phillip K.

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A2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses von Todd, Kirsten L., Lai, Junyun, Sek, Kevin, Huang, Yu-Kuan, Newman, Dane M., Derrick, Emily B., Koay, Hui-Fern, Nguyen, Dat, Hoang, Thang X., Petley, Emma V., Chan, Cheok Weng, Munoz, Isabelle, House, Imran G., Lee, Joel N., Kim, Joelle S., Li, Jasmine, Tong, Junming, N. de Menezes, Maria, Scheffler, Christina M., Yap, Kah Min, Chen, Amanda X. Y., Dunbar, Phoebe A., Haugen, Brandon, Parish, Ian A., Johnstone, Ricky W., Darcy, Phillip K., Beavis, Paul A.

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Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade von House, Imran G, Savas, Peter, Lai, Junyun, Chen, Amanda X Y, Oliver, Amanda J, Teo, Zhi L, Todd, Kirsten L, Henderson, Melissa A, Giuffrida, Lauren, Petley, Emma V, Sek, Kevin, Mardiana, Sherly, Gide, Tuba N, Quek, Camelia, Scolyer, Richard A, Long, Georgina V, Wilmott, James S, Loi, Sherene, Darcy, Phillip K, Beavis, Paul A

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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy von Chan, Jack D., Scheffler, Christina M., Munoz, Isabelle, Sek, Kevin, Lee, Joel N., Huang, Yu-Kuan, Yap, Kah Min, Saw, Nicole Y. L., Li, Jasmine, Chen, Amanda X. Y., Chan, Cheok Weng, Derrick, Emily B., Todd, Kirsten L., Tong, Junming, Dunbar, Phoebe A., Li, Jiawen, Hoang, Thang X., de Menezes, Maria N., Petley, Emma V., Kim, Joelle S., Nguyen, Dat, Leung, Patrick S. K., So, Joan, Deguit, Christian, Zhu, Joe, House, Imran G., Kats, Lev M., Scott, Andrew M., Solomon, Benjamin J., Harrison, Simon J., Oliaro, Jane, Parish, Ian A., Quinn, Kylie M., Neeson, Paul J., Slaney, Clare Y., Lai, Junyun, Beavis, Paul A., Darcy, Phillip K.

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Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies von Nüssing, Simone, House, Imran G, Kearney, Conor J, Chen, Amanda X Y, Vervoort, Stephin J, Beavis, Paul A, Oliaro, Jane, Johnstone, Ricky W, Trapani, Joseph A, Parish, Ian A

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IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors von Giuffrida, Lauren, Sek, Kevin, Henderson, Melissa A., House, Imran G., Lai, Junyun, Chen, Amanda X.Y., Todd, Kirsten L., Petley, Emma V., Mardiana, Sherly, Todorovski, Izabela, Gruber, Emily, Kelly, Madison J., Solomon, Benjamin J., Vervoort, Stephin J., Johnstone, Ricky W., Parish, Ian A., Neeson, Paul J., Kats, Lev M., Darcy, Phillip K., Beavis, Paul A.

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A New Safety Approach Allowing Reversible Control of CAR T Cell Responses von Chen, Amanda X.Y., House, Imran G., Beavis, Paul A., Darcy, Phillip K.

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity von House, Imran G., Derrick, Emily B., Sek, Kevin, Chen, Amanda X.Y., Li, Jasmine, Lai, Junyun, Todd, Kirsten L., Munoz, Isabelle, Michie, Jessica, Chan, Cheok Weng, Huang, Yu-Kuan, Chan, Jack D., Petley, Emma V., Tong, Junming, Nguyen, DatMinh, Engel, Sven, Savas, Peter, Hogg, Simon J., Vervoort, Stephin J., Kearney, Conor J., Burr, Marian L., Lam, Enid Y.N., Gilan, Omer, Bedoui, Sammy, Johnstone, Ricky W., Dawson, Mark A., Loi, Sherene, Darcy, Phillip K., Beavis, Paul A.

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity von House, Imran G., Derrick, Emily B., Sek, Kevin, Chen, Amanda X.Y., Li, Jasmine, Lai, Junyun, Todd, Kirsten L., Munoz, Isabelle, Michie, Jessica, Chan, Cheok Weng, Huang, Yu-Kuan, Chan, Jack D., Petley, Emma V., Tong, Junming, Nguyen, DatMinh, Engel, Sven, Savas, Peter, Hogg, Simon J., Vervoort, Stephin J., Kearney, Conor J., Burr, Marian L., Lam, Enid Y.N., Gilan, Omer, Bedoui, Sammy, Johnstone, Ricky W., Dawson, Mark A., Loi, Sherene, Darcy, Phillip K., Beavis, Paul A.

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The Genome as an Evolutionary Timepiece von Ho, Simon Y W, Chen, Amanda X Y, Lins, Luana S F, Duchêne, David A, Lo, Nathan

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CD4+ chimeric antigen receptor T cells in for the long journey von Chen, Amanda XY, Derrick, Emily B, Beavis, Paul A, House, Imran G

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A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia von Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.

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Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma von Moore, Amanda R, Ceraudo, Emilie, Sher, Jessica J, Guan, Youxin, Shoushtari, Alexander N, Chang, Matthew T, Zhang, Jenny Q, Walczak, Edward G, Kazmi, Manija A, Taylor, Barry S, Huber, Thomas, Chi, Ping, Sakmar, Thomas P, Chen, Yu

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Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus von Bowman, Louise, Mafham, Marion, Wallendszus, Karl, Stevens, Will, Buck, Georgina, Barton, Jill, Murphy, Kevin, Aung, Theingi, Haynes, Richard, Cox, Jolyon, Murawska, Aleksandra, Young, Allen, Lay, Michael, Chen, Fang, Sammons, Emily, Waters, Emma, Adler, Amanda, Bodansky, Jonathan, Farmer, Andrew, McPherson, Roger, Neil, Andrew, Simpson, David, Peto, Richard, Baigent, Colin, Collins, Rory, Parish, Sarah, Armitage, Jane

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Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus von Bowman, Louise, Mafham, Marion, Wallendszus, Karl, Stevens, Will, Buck, Georgina, Barton, Jill, Murphy, Kevin, Aung, Theingi, Haynes, Richard, Cox, Jolyon, Murawska, Aleksandra, Young, Allen, Lay, Michael, Chen, Fang, Sammons, Emily, Waters, Emma, Adler, Amanda, Bodansky, Jonathan, Farmer, Andrew, McPherson, Roger, Neil, Andrew, Simpson, David, Peto, Richard, Baigent, Colin, Collins, Rory, Parish, Sarah, Armitage, Jane

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Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation von Chaudhuri, Swarnava, Li, Liping, Zimmerman, Matthew, Chen, Yuemeng, Chen, Yu-Xiang, Toosky, Melody N, Gardner, Michelle, Pan, Miaomiao, Li, Yang-Yang, Kawaji, Qingwen, Zhu, Jun-Hao, Su, Hong-Wei, Martinot, Amanda J, Rubin, Eric J, Dartois, Veronique Anne, Javid, Babak

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Role of MAIT cells in gastrointestinal tract bacterial infections in humans: More than a gut feeling von Zheng, Yichao, Han, Fei, Ho, Amanda, Xue, Yiting, Wu, Zhengyu, Chen, Xingchi, Sandberg, Johan K., Ma, Shaohua, Leeansyah, Edwin

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Novel insights into genetic susceptibility for colorectal cancer from transcriptome-wide association and functional investigation von Chen, Zhishan, Song, Wenqiang, Shu, Xiao-Ou, Wen, Wanqing, Devall, Matthew, Dampier, Christopher, Moratalla-Navarro, Ferran, Cai, Qiuyin, Long, Jirong, Van Kaer, Luc, Wu, Lan, Huyghe, Jeroen R, Thomas, Minta, Hsu, Li, Woods, Michael O, Albanes, Demetrius, Buchanan, Daniel D, Gsur, Andrea, Hoffmeister, Michael, Vodicka, Pavel, Wolk, Alicja, Marchand, Loic Le, Wu, Anna H, Phipps, Amanda I, Moreno, Victor, Ulrike, Peters, Zheng, Wei, Casey, Graham, Guo, Xingyi

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