First-in-human study to evaluate safety, tolerability, and immunogenicity of heterologous regimens using the multivalent filovirus vaccines Ad26.Filo and MVA-BN-Filo administered i... von Bockstal, Viki, Shukarev, Georgi, McLean, Chelsea, Goldstein, Neil, Bart, Stephan, Gaddah, Auguste, Anumenden, Dickson, Stoop, Jeroen N, Marit de Groot, Anne, Pau, Maria G, Hendriks, Jenny, De Rosa, Stephen C, Cohen, Kristen W, McElrath, M. Juliana, Callendret, Benoit, Luhn, Kerstin, Douoguih, Macaya, Robinson, Cynthia

Volltext

Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours von Fernandes Neto, João M., Nadal, Ernest, Bosdriesz, Evert, Ooft, Salo N., Farre, Lourdes, McLean, Chelsea, Klarenbeek, Sjoerd, Jurgens, Anouk, Hagen, Hannes, Wang, Liqin, Felip, Enriqueta, Martinez-Marti, Alex, Vidal, August, Voest, Emile, Wessels, Lodewyk F. A., van Tellingen, Olaf, Villanueva, Alberto, Bernards, René

Volltext

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma von Vlaming, Hanneke, McLean, Chelsea M, Korthout, Tessy, Alemdehy, Mir Farshid, Hendriks, Sjoerd, Lancini, Cesare, Palit, Sander, Klarenbeek, Sjoerd, Kwesi-Maliepaard, Eliza Mari, Molenaar, Thom M, Hoekman, Liesbeth, Schmidlin, Thierry T, Altelaar, Af Maarten, van Welsem, Tibor, Dannenberg, Jan-Hermen, Jacobs, Heinz, van Leeuwen, Fred

Volltext

BTK inhibitors synergise with 5‐FU to treat drug‐resistant TP53‐null colon cancers von Lavitrano, Marialuisa, Ianzano, Leonarda, Bonomo, Sara, Cialdella, Annamaria, Cerrito, Maria Grazia, Pisano, Fabio, Missaglia, Carola, Giovannoni, Roberto, Romano, Gabriele, McLean, Chelsea M, Voest, Emile E, D'Amato, Filomena, Noli, Barbara, Ferri, Gian Luca, Agostini, Marco, Pucciarelli, Salvatore, Helin, Kristian, Leone, Biagio E, Canzonieri, Vincenzo, Grassilli, Emanuela

Volltext

Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26.ZEBOV/MVA-BN-Filo von Blengio, Fabiola, Hocini, Hakim, Richert, Laura, Lefebvre, Cécile, Durand, Mélany, Hejblum, Boris, Tisserand, Pascaline, McLean, Chelsea, Luhn, Kerstin, Thiebaut, Rodolphe, Levy, Yves

Volltext

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma von Vlaming, Hanneke, McLean, Chelsea M, Korthout, Tessy, Alemdehy, Mir Farshid, Hendriks, Sjoerd, Lancini, Cesare, Palit, Sander, Klarenbeek, Sjoerd, Kwesi‐Maliepaard, Eliza Mari, Molenaar, Thom M, Hoekman, Liesbeth, Schmidlin, Thierry T, Altelaar, AF Maarten, van Welsem, Tibor, Dannenberg, Jan‐Hermen, Jacobs, Heinz, van Leeuwen, Fred

Volltext

Fatty acid 16:4(n‐3) stimulates a GPR120‐induced signaling cascade in splenic macrophages to promote chemotherapy resistance von Houthuijzen, Julia M., Oosterom, Ilse, Hudson, Brian D., Hirasawa, Akira, Daenen, Laura G. M., McLean, Chelsea M., Hansen, Steffen V. F., Jaarsveld, Marijn T. M., Peeper, Daniel S., Sadatmand, Sahar Jafari, Roodhart, Jeanine M. L., Lest, Chris H. A., Ulven, Trond, Ishihara, Kenji, Milligan, Graeme, Voest, Emile E.

Volltext

Lot-to-lot consistency, immunogenicity, and safety of the Ad26.ZEBOV, MVA-BN-Filo Ebola virus vaccine regimen: A phase 3, randomized, double-blind, placebo-controlled trial von Goldstein, Neil, McLean, Chelsea, Gaddah, Auguste, Doua, Joachim, Keshinro, Babajide, Bus-Jacobs, Linda, Hendriks, Jenny, Luhn, Kerstin, Robinson, Cynthia, Douoguih, Macaya

Volltext

HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis von Zimberlin, Cheryl D., Lancini, Cesare, Sno, Rachel, Rosekrans, Sanne L., McLean, Chelsea M., Vlaming, Hanneke, Brink, Gijs R., Bots, Michael, Medema, Jan Paul, Dannenberg, Jan‐Hermen

Volltext

Persistence of immunological memory as a potential correlate of long-term, vaccine-induced protection against Ebola virus disease in humans von McLean, Chelsea, Dijkman, Karin, Gaddah, Auguste, Keshinro, Babajide, Katwere, Michael, Douoguih, Macaya, Robinson, Cynthia, Solforosi, Laura, Czapska-Casey, Dominika, Dekking, Liesbeth, Wollmann, Yvonne, Volkmann, Ariane, Pau, Maria Grazia, Callendret, Benoit, Sadoff, Jerry, Schuitemaker, Hanneke, Zahn, Roland, Luhn, Kerstin, Hendriks, Jenny, Roozendaal, Ramon

Volltext

Some reflections on well designed 'natural' systems and a circular economy von McLean, Chelsea

Volltext

Education enabling a circular economy von McLean, Chelsea

Volltext

Prediction of long-term humoral response induced by the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo vaccine against Ebola von Alexandre, Marie, Prague, Mélanie, McLean, Chelsea, Bockstal, Viki, Douoguih, Macaya, Thiébaut, Rodolphe

Volltext

Immunogenicity of an Extended Dose Interval for the Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccine Regimen in Adults and Children in the Democratic Republic of the Congo von Choi, Edward Man-Lik, Kasonia, Kambale, Kavunga-Membo, Hugo, Mukadi-Bamuleka, Daniel, Soumah, Aboubacar, Mossoko, Zephyrin, Edwards, Tansy, Tetsa-Tata, Darius, Makarimi, Rockyath, Toure, Oumar, Mambula, Grace, Brindle, Hannah, Camacho, Anton, Connor, Nicholas E, Mukadi, Pierre, McLean, Chelsea, Keshinro, Babajide, Gaddah, Auguste, Robinson, Cynthia, Luhn, Kerstin, Foster, Julie, Roberts, Chrissy H, Johnson, John Emery, Imbault, Nathalie, Bausch, Daniel G, Grais, Rebecca F, Watson-Jones, Deborah, Muyembe-Tamfum, Jean Jacques

Volltext

Zero waste: Less food to landfill for a more sustainable future von Chelsea McLean

Volltext

Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus von Lindroth, Anders M, Park, Yoon Jung, McLean, Chelsea M, Dokshin, Gregoriy A, Persson, Jenna M, Herman, Herry, Pasini, Diego, Miró, Xavier, Donohoe, Mary E, Lee, Jeannie T, Helin, Kristian, Soloway, Paul D

Volltext

Imprinted DNA methylation reconstituted at a non-imprinted locus von Taylor, David H, McLean, Chelsea M, Wu, Warren L, Wang, Alex B, Soloway, Paul D

Volltext

Randomized Trial of Vaccines for Zaire Ebola Virus Disease von Kieh, Mark, Richert, Laura, Beavogui, Abdoul H, Grund, Birgit, Leigh, Bailah, D'Ortenzio, Eric, Doumbia, Seydou, Lhomme, Edouard, Sow, Samba, Vatrinet, Renaud, Roy, Céline, Kennedy, Stephen B, Faye, Sylvain, Lees, Shelley, Millimouno, Niouma P, Camara, Alseny M, Samai, Mohamed, Deen, Gibrilla F, Doumbia, Moussa, Espérou, Hélène, Pierson, Jerome, Watson-Jones, Deborah, Diallo, Alpha, Wentworth, Deborah, McLean, Chelsea, Simon, Jakub, Wiedemann, Aurélie, Dighero-Kemp, Bonnie, Hensley, Lisa, Lane, H Clifford, Levy, Yves, Piot, Peter, Greenwood, Brian, Chêne, Geneviève, Neaton, James, Yazdanpanah, Yazdan

Volltext

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8⁺ T cells von Kwesi-Maliepaard, Eliza Mari, Aslam, Muhammad Assad, Alemdehy, Mir Farshid, van den Brand, Teun, McLean, Chelsea, Vlaming, Hanneke, van Welsem, Tibor, Korthout, Tessy, Lancini, Cesare, Hendriks, Sjoerd, Ahrends, Tomasz, van Dinther, Dieke, den Haan, Joke M. M., Borst, Jannie, de Wit, Elzo, van Leeuwen, Fred, Jacobs, Heinz

Volltext

Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccine regimen plus Ad26.ZEBOV booster at 1 year versus 2 years in health-care and front-line workers in the Democratic Republic of the... von Larivière, Ynke, Matuvanga, Trésor Zola, Osang'ir, Bernard Isekah, Milolo, Solange, Meta, Rachel, Kimbulu, Primo, Robinson, Cynthia, Katwere, Michael, McLean, Chelsea, Lemey, Gwen, Matangila, Junior, Maketa, Vivi, Mitashi, Patrick, Van geertruyden, Jean-Pierre, Van Damme, Pierre, Muhindo-Mavoko, Hypolite

Volltext