Enhanced preservation of the human intestinal microbiota by ridinilazole, a novel Clostridium difficile-targeting antibacterial, compared to vancomycin von Thorpe, Cheleste M, Kane, Anne V, Chang, Justin, Tai, Albert, Vickers, Richard J, Snydman, David R

Volltext

AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP von Paton, Adrienne W., Beddoe, Travis, Thorpe, Cheleste M., Whisstock, James C., Wilce, Matthew C. J., Rossjohn, Jamie, Talbot, Ursula M., Paton, James C.

Volltext

Role of Lipid Rafts and Flagellin in Invasion of Colonic Epithelial Cells by Shiga-Toxigenic Escherichia coli O113:H21 von ROGERS, Trisha J, THORPE, Cheleste M, PATON, Adrienne W, PATON, James C

Volltext

Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin von Wong, John, Smith, Logan B., Magun, Eli A., Engstrom, Thomas, Kelley-Howard, Kirsten, Jandhyala, Dakshina M., Thorpe, Cheleste M., Magun, Bruce E., Wood, Lisa J.

Volltext

Critical Roles for stx2, eae, and tir in Enterohemorrhagic Escherichia coli-Induced Diarrhea and Intestinal Inflammation in Infant Rabbits von RITCHIE, Jennifer M, THORPE, Cheleste M, ROGERS, Arlin B, WALDOR, Matthew K

Volltext

A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response von Jandhyala, Dakshina M, Wong, John, Mantis, Nicholas J, Magun, Bruce E, Leong, John M, Thorpe, Cheleste M

Volltext

Ridinilazole, a narrow spectrum antibiotic for treatment of Clostridioides difficile infection, enhances preservation of microbiota-dependent bile acids von Qian, Xi, Yanagi, Karin, Kane, Anne V, Alden, Nicholas, Lei, Ming, Snydman, David R, Vickers, Richard J, Lee, Kyongbum, Thorpe, Cheleste M

Volltext

Citrobacter rodentium(ϕStx2dact), a murine infection model for enterohemorrhagic Escherichia coli von Thorpe, Cheleste M, Pulsifer, Amanda R, Osburne, Marcia S, Vanaja, Sivapriya Kailasan, Leong, John M

Volltext

Shiga Toxin 1 Triggers a Ribotoxic Stress Response Leading to p38 and JNK Activation and Induction of Apoptosis in Intestinal Epithelial Cells von SMITH, Wendy E, KANE, Anne V, CAMPBELL, Sausan T, ACHESON, David W. K, COCHRAN, Brent H, THORPE, Cheleste M

Volltext

Shiga Toxin 2 and Flagellin from Shiga-Toxigenic Escherichia coli Superinduce Interleukin-8 through Synergistic Effects on Host Stress-Activated Protein Kinase Activation von Jandhyala, Dakshina M, Rogers, Trisha J, Kane, Anne, Paton, Adrienne W, Paton, James C, Thorpe, Cheleste M

Volltext

Shiga Toxin Translocation across Intestinal Epithelial Cells Is Enhanced by Neutrophil Transmigration von HURLEY, Bryan P, THORPE, Cheleste M, ACHESON, David W. K

Volltext

Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus von Van, Nhi, Degefu, Yonatan N, Leus, Pathricia A, Larkins-Ford, Jonah, Klickstein, Jacob, Maurer, Florian P, Stone, David, Poonawala, Husain, Thorpe, Cheleste M, Smith, 2nd, Trever C, Aldridge, Bree B

Volltext

The Emerging Clinical Importance of Non-O157 Shiga Toxin—Producing Escherichia coli von Hughes, James M., Wilson, Mary E., Johnson, Kristine E., Thorpe, Cheleste M., Sears, Cynthia L.

Volltext

Shiga Toxins Induce, Superinduce, and Stabilize a Variety of C-X-C Chemokine mRNAs in Intestinal Epithelial Cells, Resulting in Increased Chemokine Expression von THORPE, Cheleste M, SMITH, Wendy E, HURLEY, Bryan P, ACHESON, David W. K

Volltext

Antimicrobial susceptibility and ribotypes of Clostridium difficile isolates from a Phase 2 clinical trial of ridinilazole (SMT19969) and vancomycin von Snydman, David R, McDermott, Laura A, Thorpe, Cheleste M, Chang, Justin, Wick, Jenna, Walk, Seth T, Vickers, Richard J

Volltext

ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression von Jandhyala, Dakshina M, Ahluwalia, Amrita, Obrig, Tom, Thorpe, Cheleste M

Volltext

Shiga Toxin—Producing Escherichia coli Infection von Thorpe, Cheleste M.

Volltext

Borrelia burgdorferi-Induced Expression of Matrix Metalloproteinases from Human Chondrocytes Requires Mitogen-Activated Protein Kinase and Janus Kinase/Signal Transducer and Activa... von BEHERA, Aruna K, THORPE, Cheleste M, KIDDER, J. Michael, SMITH, Wendy, HILDEBRAND, Ethan, HU, Linden T

Volltext

Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways von Wolfson, Jennifer J, May, Kerrie L, Thorpe, Cheleste M, Jandhyala, Dakshina M, Paton, James C, Paton, Adrienne W

Volltext

Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation von Jandhyala, Dakshina M, Ahluwalia, Amrita, Schimmel, Jennifer J, Rogers, Arlin B, Leong, John M, Thorpe, Cheleste M

Volltext