Regulation of Ferroptotic Cancer Cell Death by GPX4 von Yang, Wan Seok, SriRamaratnam, Rohitha, Welsch, Matthew E., Shimada, Kenichi, Skouta, Rachid, Viswanathan, Vasanthi S., Cheah, Jaime H., Clemons, Paul A., Shamji, Alykhan F., Clish, Clary B., Brown, Lewis M., Girotti, Albert W., Cornish, Virginia W., Schreiber, Stuart L., Stockwell, Brent R.

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Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives von Pompeo, Matthew M, Cheah, Jaime H, Movassaghi, Mohammad

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Correlating chemical sensitivity and basal gene expression reveals mechanism of action von Rees, Matthew G, Seashore-Ludlow, Brinton, Cheah, Jaime H, Adams, Drew J, Price, Edmund V, Gill, Shubhroz, Javaid, Sarah, Coletti, Matthew E, Jones, Victor L, Bodycombe, Nicole E, Soule, Christian K, Alexander, Benjamin, Li, Ava, Montgomery, Philip, Kotz, Joanne D, Hon, C Suk-Yee, Munoz, Benito, Liefeld, Ted, Dančík, Vlado, Haber, Daniel A, Clish, Clary B, Bittker, Joshua A, Palmer, Michelle, Wagner, Bridget K, Clemons, Paul A, Shamji, Alykhan F, Schreiber, Stuart L

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Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery von Boehnke, Natalie, Straehla, Joelle P, Safford, Hannah C, Kocak, Mustafa, Rees, Matthew G, Ronan, Melissa, Rosenberg, Danny, Adelmann, Charles H, Chivukula, Raghu R, Nabar, Namita, Berger, Adam G, Lamson, Nicholas G, Cheah, Jaime H, Li, Hojun, Roth, Jennifer A, Koehler, Angela N, Hammond, Paula T

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An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules von Basu, Amrita, Bodycombe, Nicole E., Cheah, Jaime H., Price, Edmund V., Liu, Ke, Schaefer, Giannina I., Ebright, Richard Y., Stewart, Michelle L., Ito, Daisuke, Wang, Stephanie, Bracha, Abigail L., Liefeld, Ted, Wawer, Mathias, Gilbert, Joshua C., Wilson, Andrew J., Stransky, Nicolas, Kryukov, Gregory V., Dancik, Vlado, Barretina, Jordi, Garraway, Levi A., Hon, C. Suk-Yee, Munoz, Benito, Bittker, Joshua A., Stockwell, Brent R., Khabele, Dineo, Stern, Andrew M., Clemons, Paul A., Shamji, Alykhan F., Schreiber, Stuart L.

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A genetic basis for the variation in the vulnerability of cancer to DNA damage von Yard, Brian D., Adams, Drew J., Chie, Eui Kyu, Tamayo, Pablo, Battaglia, Jessica S., Gopal, Priyanka, Rogacki, Kevin, Pearson, Bradley E., Phillips, James, Raymond, Daniel P., Pennell, Nathan A., Almeida, Francisco, Cheah, Jaime H., Clemons, Paul A., Shamji, Alykhan, Peacock, Craig D., Schreiber, Stuart L., Hammerman, Peter S., Abazeed, Mohamed E.

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Concise Total Synthesis of (+)-Luteoalbusins A and B von Adams, Timothy C, Payette, Joshua N, Cheah, Jaime H, Movassaghi, Mohammad

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NMDA Receptor-Nitric Oxide Transmission Mediates Neuronal Iron Homeostasis via the GTPase Dexras1 von Cheah, Jaime H., Kim, Sangwon F., Hester, Lynda D., Clancy, Kathleen W., Patterson, Stanley E., Papadopoulos, Vassilios, Snyder, Solomon H.

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A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production von Wong, Madeline Y, Doan, Ngoc Duc, DiChiara, Andrew S, Papa, Louis J, Cheah, Jaime H, Soule, Christian K, Watson, Nicki, Hulleman, John D, Shoulders, Matthew D

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Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity von Chen, Yong, Khan, Reas S, Cwanger, Alyssa, Song, Ying, Steenstra, Catherine, Bang, Sookhee, Cheah, Jaime H, Dunaief, Joshua, Shindler, Kenneth S, Snyder, Solomon H, Kim, Sangwon F

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NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes von Adams, Drew J, Ito, Daisuke, Rees, Matthew G, Seashore-Ludlow, Brinton, Puyang, Xiaoling, Ramos, Alex H, Cheah, Jaime H, Clemons, Paul A, Warmuth, Markus, Zhu, Ping, Shamji, Alykhan F, Schreiber, Stuart L

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Synthesis of Potent Cytotoxic Epidithiodiketopiperazines Designed for Derivatization von Olsson, Chase R, Payette, Joshua N, Cheah, Jaime H, Movassaghi, Mohammad

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Computationally guided high-throughput design of self-assembling drug nanoparticles von Reker, Daniel, Rybakova, Yulia, Kirtane, Ameya R., Cao, Ruonan, Yang, Jee Won, Navamajiti, Natsuda, Gardner, Apolonia, Zhang, Rosanna M., Esfandiary, Tina, L’Heureux, Johanna, von Erlach, Thomas, Smekalova, Elena M., Leboeuf, Dominique, Hess, Kaitlyn, Lopes, Aaron, Rogner, Jaimie, Collins, Joy, Tamang, Siddartha M., Ishida, Keiko, Chamberlain, Paul, Yun, DongSoo, Lytton-Jean, Abigail, Soule, Christian K., Cheah, Jaime H., Hayward, Alison M., Langer, Robert, Traverso, Giovanni

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Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure von Katsumura, Sakie, Siddiqui, Nadeem, Goldsmith, Michael Rock, Cheah, Jaime H, Fujikawa, Teppei, Minegishi, Genki, Yamagata, Atsushi, Yabuki, Yukako, Kobayashi, Kaoru, Shirouzu, Mikako, Inagaki, Takeshi, Huang, Tim H-M, Musi, Nicolas, Topisirovic, Ivan, Larsson, Ola, Morita, Masahiro

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Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset von Seashore-Ludlow, Brinton, Rees, Matthew G, Cheah, Jaime H, Cokol, Murat, Price, Edmund V, Coletti, Matthew E, Jones, Victor, Bodycombe, Nicole E, Soule, Christian K, Gould, Joshua, Alexander, Benjamin, Li, Ava, Montgomery, Philip, Wawer, Mathias J, Kuru, Nurdan, Kotz, Joanne D, Hon, C Suk-Yee, Munoz, Benito, Liefeld, Ted, Dančík, Vlado, Bittker, Joshua A, Palmer, Michelle, Bradner, James E, Shamji, Alykhan F, Clemons, Paul A, Schreiber, Stuart L

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Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics von Liu, Gary W., Pickett, Matthew J., Kuosmanen, Johannes L. P., Ishida, Keiko, Madani, Wiam A. M., White, Georgia N., Jenkins, Joshua, Park, Sanghyun, Feig, Vivian R., Jimenez, Miguel, Karavasili, Christina, Lal, Nikhil B., Murphy, Matt, Lopes, Aaron, Morimoto, Joshua, Fitzgerald, Nina, Cheah, Jaime H., Soule, Christian K., Fabian, Niora, Hayward, Alison, Langer, Robert, Traverso, Giovanni

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Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT Network von Halvorsen, Stefan C., Benita, Yair, Hopton, Megan, Hoppe, Brooke, Gunnlaugsson, Hilmar O., Korgaonkar, Parimal, Vanderburg, Charles R., Nielsen, G. Petur, Trepanowski, Nicole, Cheah, Jaime H., Frosch, Matthew P., Schwab, Joseph H., Rosenberg, Andrew E., Hornicek, Francis J., Sassi, Slim

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Scalable, compressed phenotypic screening using pooled perturbations von Liu, Nuo, Kattan, Walaa E, Mead, Benjamin E, Kummerlowe, Conner, Cheng, Thomas, Ingabire, Sarah, Cheah, Jaime H, Soule, Christian K, Vrcic, Anita, McIninch, Jane K, Triana, Sergio, Guzman, Manuel, Dao, Tyler T, Peters, Joshua M, Lowder, Kristen E, Crawford, Lorin, Amini, Ava P, Blainey, Paul C, Hahn, William C, Cleary, Brian, Bryson, Bryan, Winter, Peter S, Raghavan, Srivatsan, Shalek, Alex K

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S -nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding von Snyder, Solomon H, Sawa, Akira, Hara, Makoto R, Agrawal, Nishant, Kim, Sangwon F, Cascio, Matthew B, Fujimuro, Masahiro, Ozeki, Yuji, Takahashi, Masaaki, Cheah, Jaime H, Tankou, Stephanie K, Hester, Lynda D, Ferris, Christopher D, Hayward, S. Diane

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Screening in serum-derived medium reveals differential response to compounds targeting metabolism von Abbott, Keene L., Ali, Ahmed, Casalena, Dominick, Do, Brian T., Ferreira, Raphael, Cheah, Jaime H., Soule, Christian K., Deik, Amy, Kunchok, Tenzin, Schmidt, Daniel R., Renner, Steffen, Honeder, Sophie E., Wu, Michelle, Chan, Sze Ham, Tseyang, Tenzin, Stoltzfus, Andrew T., Michel, Sarah L.J., Greaves, Daniel, Hsu, Peggy P., Ng, Christopher W., Zhang, Chelsea J., Farsidjani, Ali, Kent, Johnathan R., Madariaga, Maria Lucia L., Gramatikov, Iva Monique T., Matheson, Nicholas J., Lewis, Caroline A., Clish, Clary B., Rees, Matthew G., Roth, Jennifer A., Griner, Lesley Mathews, Muir, Alexander, Auld, Douglas S., Vander Heiden, Matthew G.

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