First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial von Janjigian, Yelena Y, Maron, Steven B, Chatila, Walid K, Millang, Brittanie, Chavan, Shweta S, Alterman, Carly, Chou, Joanne F, Segal, Michal F, Simmons, Marc Z, Momtaz, Parisa, Shcherba, Marina, Ku, Geoffrey Y, Zervoudakis, Alice, Won, Elizabeth S, Kelsen, David P, Ilson, David H, Nagy, Rebecca J, Lanman, Richard B, Ptashkin, Ryan N, Donoghue, Mark T A, Capanu, Marinela, Taylor, Barry S, Solit, David B, Schultz, Nikolaus, Hechtman, Jaclyn F

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Genomic Landscape of Uterine Sarcomas Defined Through Prospective Clinical Sequencing von Hensley, Martee L., Chavan, Shweta S., Solit, David B., Murali, Rajmohan, Soslow, Robert, Chiang, Sarah, Jungbluth, Achim A., Bandlamudi, Chaitanya, Srinivasan, Preethi, Tap, William D., Rosenbaum, Evan, Taylor, Barry S., Donoghue, Mark T. A., Hyman, David M.

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Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma von Weinhold, Niels, Ashby, Cody, Rasche, Leo, Chavan, Shweta S., Stein, Caleb, Stephens, Owen W., Tytarenko, Ruslana, Bauer, Michael A., Meissner, Tobias, Deshpande, Shayu, Patel, Purvi H., Buzder, Timea, Molnar, Gabor, Peterson, Erich A., van Rhee, Frits, Zangari, Maurizio, Thanendrarajan, Sharmilan, Schinke, Carolina, Tian, Erming, Epstein, Joshua, Barlogie, Bart, Davies, Faith E., Heuck, Christoph J., Walker, Brian A, Morgan, Gareth J.

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The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma von Pawlyn, Charlotte, Kaiser, Martin F, Heuck, Christoph, Melchor, Lorenzo, Wardell, Christopher P, Murison, Alex, Chavan, Shweta S, Johnson, David C, Begum, Dil B, Dahir, Nasrin M, Proszek, Paula Z, Cairns, David A, Boyle, Eileen M, Jones, John R, Cook, Gordon, Drayson, Mark T, Owen, Roger G, Gregory, Walter M, Jackson, Graham H, Barlogie, Bart, Davies, Faith E, Walker, Brian A, Morgan, Gareth J

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Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation von Quintanal-Villalonga, Alvaro, Taniguchi, Hirokazu, Zhan, Yingqian A., Hasan, Maysun M., Chavan, Shweta S., Meng, Fanli, Uddin, Fathema, Manoj, Parvathy, Donoghue, Mark T. A., Won, Helen H., Chan, Joseph M., Ciampricotti, Metamia, Chow, Andrew, Offin, Michael, Chang, Jason C., Ray-Kirton, Jordana, Tischfield, Sam E., Egger, Jacklynn, Bhanot, Umesh K., Linkov, Irina, Asher, Marina, Sinha, Sonali, Silber, Joachim, Iacobuzio-Donahue, Christine A., Roehrl, Michael H., Hollmann, Travis J., Yu, Helena A., Qiu, Juan, de Stanchina, Elisa, Baine, Marina K., Rekhtman, Natasha, Poirier, John T., Loomis, Brian, Koche, Richard P., Rudin, Charles M., Sen, Triparna

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Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas von Jonsson, Philip, Lin, Andrew L, Young, Robert J, DiStefano, Natalie M, Hyman, David M, Li, Bob T, Berger, Michael F, Zehir, Ahmet, Ladanyi, Marc, Solit, David B, Arnold, Angela G, Stadler, Zsofia K, Mandelker, Diana, Goldberg, Michael E, Chmielecki, Juliann, Pourmaleki, Maryam, Ogilvie, Shahiba Q, Chavan, Shweta S, McKeown, Andrew T, Manne, Malbora, Hyde, Allison, Beal, Kathryn, Yang, T Jonathan, Nolan, Craig P, Pentsova, Elena, Omuro, Antonio, Gavrilovic, Igor T, Kaley, Thomas J, Diamond, Eli L, Stone, Jacqueline B, Grommes, Christian, Boire, Adrienne, Daras, Mariza, Piotrowski, Anna F, Miller, Alexandra M, Gutin, Philip H, Chan, Timothy A, Tabar, Viviane S, Brennan, Cameron W, Rosenblum, Marc, DeAngelis, Lisa M, Mellinghoff, Ingo K, Taylor, Barry S

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Tumour lineage shapes BRCA-mediated phenotypes von Jonsson, Philip, Bandlamudi, Chaitanya, Cheng, Michael L., Srinivasan, Preethi, Chavan, Shweta S., Friedman, Noah D., Rosen, Ezra Y., Richards, Allison L., Bouvier, Nancy, Selcuklu, S. Duygu, Bielski, Craig M., Abida, Wassim, Mandelker, Diana, Birsoy, Ozge, Zhang, Liying, Zehir, Ahmet, Donoghue, Mark T. A., Baselga, José, Offit, Kenneth, Scher, Howard I., O’Reilly, Eileen M., Stadler, Zsofia K., Schultz, Nikolaus, Socci, Nicholas D., Viale, Agnes, Ladanyi, Marc, Robson, Mark E., Hyman, David M., Berger, Michael F., Solit, David B., Taylor, Barry S.

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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC von Taniguchi, Hirokazu, Caeser, Rebecca, Chavan, Shweta S., Zhan, Yingqian A., Chow, Andrew, Manoj, Parvathy, Uddin, Fathema, Kitai, Hidenori, Qu, Rui, Hayatt, Omar, Shah, Nisargbhai S., Quintanal Villalonga, Álvaro, Allaj, Viola, Nguyen, Evelyn M., Chan, Joseph, Michel, Adam O., Mukae, Hiroshi, de Stanchina, Elisa, Rudin, Charles M., Sen, Triparna

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Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts von Caeser, Rebecca, Egger, Jacklynn V., Chavan, Shweta, Socci, Nicholas D., Jones, Caitlin Byrne, Kombak, Faruk Erdem, Asher, Marina, Roehrl, Michael H., Shah, Nisargbhai S., Allaj, Viola, Manoj, Parvathy, Tischfield, Sam E., Kulick, Amanda, Meneses, Maximiliano, Iacobuzio-Donahue, Christine A., Lai, W. Victoria, Bhanot, Umeshkumar, Baine, Marina K., Rekhtman, Natasha, Hollmann, Travis J., de Stanchina, Elisa, Poirier, John T., Rudin, Charles M., Sen, Triparna

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The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer von Chow, Andrew, Uddin, Fathema Z., Liu, Michael, Dobrin, Anton, Nabet, Barzin Y., Mangarin, Levi, Lavin, Yonit, Rizvi, Hira, Tischfield, Sam E., Quintanal-Villalonga, Alvaro, Chan, Joseph M., Shah, Nisargbhai, Allaj, Viola, Manoj, Parvathy, Mattar, Marissa, Meneses, Maximiliano, Landau, Rebecca, Ward, Mariana, Kulick, Amanda, Kwong, Charlene, Wierzbicki, Matthew, Yavner, Jessica, Egger, Jacklynn, Chavan, Shweta S., Farillas, Abigail, Holland, Aliya, Sridhar, Harsha, Ciampricotti, Metamia, Hirschhorn, Daniel, Guan, Xiangnan, Richards, Allison L., Heller, Glenn, Mansilla-Soto, Jorge, Sadelain, Michel, Klebanoff, Christopher A., Hellmann, Matthew D., Sen, Triparna, de Stanchina, Elisa, Wolchok, Jedd D., Merghoub, Taha, Rudin, Charles M.

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The context-specific role of germline pathogenicity in tumorigenesis von Srinivasan, Preethi, Bandlamudi, Chaitanya, Jonsson, Philip, Kemel, Yelena, Chavan, Shweta S., Richards, Allison L., Penson, Alexander V., Bielski, Craig M., Fong, Christopher, Syed, Aijazuddin, Jayakumaran, Gowtham, Prasad, Meera, Hwee, Jason, Sumer, Selcuk Onur, de Bruijn, Ino, Li, Xiang, Gao, JianJiong, Schultz, Nikolaus, Cambria, Roy, Galle, Jesse, Mukherjee, Semanti, Vijai, Joseph, Cadoo, Karen A., Carlo, Maria I., Walsh, Michael F., Mandelker, Diana, Ceyhan-Birsoy, Ozge, Shia, Jinru, Zehir, Ahmet, Ladanyi, Marc, Hyman, David M., Zhang, Liying, Offit, Kenneth, Robson, Mark E., Solit, David B., Stadler, Zsofia K., Berger, Michael F., Taylor, Barry S.

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Role of CD38 in anti-tumor immunity of small cell lung cancer von Taniguchi, Hirokazu, Chavan, Shweta S, Chow, Andrew, Chan, Joseph M, Mukae, Hiroshi, Rudin, Charles M, Sen, Triparna

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Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy von Quintanal-Villalonga, Alvaro, Taniguchi, Hirokazu, Hao, Yuan, Chow, Andrew, Zhan, Yingqian A, Chavan, Shweta S, Uddin, Fathema, Allaj, Viola, Manoj, Parvathy, Shah, Nisargbhai S, Chan, Joseph M, Offin, Michael, Ciampricotti, Metamia, Ray-Kirton, Jordana, Egger, Jacklynn, Bhanot, Umesh, Linkov, Irina, Asher, Marina, Roehrl, Michael H, Qiu, Juan, de Stanchina, Elisa, Hollmann, Travis J, Koche, Richard P, Sen, Triparna, Poirier, John T, Rudin, Charles M

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Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation von Quintanal-Villalonga, Alvaro, Taniguchi, Hirokazu, Zhan, Yingqian A., Hasan, Maysun M., Chavan, Shweta S., Meng, Fanli, Uddin, Fathema, Allaj, Viola, Manoj, Parvathy, Shah, Nisargbhai S., Chan, Joseph M., Ciampricotti, Metamia, Chow, Andrew, Offin, Michael, Ray-Kirton, Jordana, Egger, Jacklynn D., Bhanot, Umesh K., Linkov, Irina, Asher, Marina, Roehrl, Michael H., Ventura, Katia, Qiu, Juan, de Stanchina, Elisa, Chang, Jason C., Rekhtman, Natasha, Houck-Loomis, Brian, Koche, Richard P., Yu, Helena A., Sen, Triparna, Rudin, Charles M.

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Germ cell tumors and associated hematologic malignancies evolve from a common shared precursor von Taylor, Justin, Donoghue, Mark T. A., Ho, Caleb, Petrova-Drus, Kseniya, Al-Ahmadie, Hikmat A., Funt, Samuel A., Zhang, Yanming, Aypar, Umut, Rao, Pavitra, Chavan, Shweta S., Haddadin, Michael, Tamari, Roni, Giralt, Sergio, Tallman, Martin S., Rampal, Raajit K., Baez, Priscilla, Kappagantula, Rajya, Kosuri, Satyajit, Dogan, Ahmet, Tickoo, Satish K., Reuter, Victor E., Bosl, George J., Iacobuzio-Donahue, Christine A., Solit, David B., Taylor, Barry S., Feldman, Darren R., Abdel-Wahab, Omar

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Phosphoproteomic analyses reveal signaling pathways that facilitate lytic gammaherpesvirus replication von Stahl, James A, Chavan, Shweta S, Sifford, Jeffrey M, MacLeod, Veronica, Voth, Daniel E, Edmondson, Ricky D, Forrest, J Craig

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New hydroxyproline radiocarbon dates from Sungir, Russia, confirm early Mid Upper Palaeolithic burials in Eurasia von Nalawade-Chavan, Shweta, McCullagh, James, Hedges, Robert

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Revealing the inherent heterogeneity of human malignancies by variant consensus strategies coupled with cancer clonal analysis von Peterson, Erich A, Chavan, Shweta S, Bauer, Michael A, Heuck, Christoph J, Johann, Donald J

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Leveraging the new with the old: providing a framework for the integration of historic microarray studies with next generation sequencing von Bauer, Michael A, Chavan, Shweta S, Peterson, Erich A, Heuck, Christoph J, Johann, Donald J

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Towards the integration, annotation and association of historical microarray experiments with RNA-seq von Chavan, Shweta S, Bauer, Michael A, Peterson, Erich A, Heuck, Christoph J, Johann, Jr, Donald J

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