Revealing molecular determinants governing mambalgin-3 pharmacology at acid-sensing ion channel 1 variants von Cristofori-Armstrong, Ben, Budusan, Elena, Smith, Jennifer J., Reynaud, Steve, Voll, Kerstin, Chassagnon, Irène R., Durek, Thomas, Rash, Lachlan D.

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The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: Importance of interactions at the channel subunit interface and potential for engineer... von Cristofori-Armstrong, Ben, Saez, Natalie J., Chassagnon, Irène R., King, Glenn F., Rash, Lachlan D.

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PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a von McCarthy, Claudia A., Rash, Lachlan D., Chassagnon, Irène R., King, Glenn F., Widdop, Robert E.

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A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a von Saez, Natalie J, Mobli, Mehdi, Bieri, Michael, Chassagnon, Irène R, Malde, Alpeshkumar K, Gamsjaeger, Roland, Mark, Alan E, Gooley, Paul R, Rash, Lachlan D, King, Glenn F

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Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid‐sensing ion channel 1a von Saez, Natalie J, Deplazes, Evelyne, Cristofori‐Armstrong, Ben, Chassagnon, Irène R, Lin, Xiaozhen, Mobli, Mehdi, Mark, Alan E, Rash, Lachlan D, King, Glenn F

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Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a von Chassagnon, Irène R., McCarthy, Claudia A., Chin, Yanni K.-Y., Pineda, Sandy S., Keramidas, Angelo, Mobli, Mehdi, Pham, Vi, De Silva, T. Michael, Lynch, Joseph W., Widdop, Robert E., Rash, Lachlan D., King, Glenn F.

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Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin von Piper, Sarah J, Brillault, Lou, Rothnagel, Rosalba, Croll, Tristan I, Box, Joseph K, Chassagnon, Irene, Scherer, Sebastian, Goldie, Kenneth N, Jones, Sandra A, Schepers, Femke, Hartley-Tassell, Lauren, Ve, Thomas, Busby, Jason N, Dalziel, Julie E, Lott, J Shaun, Hankamer, Ben, Stahlberg, Henning, Hurst, Mark R H, Landsberg, Michael J

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The ABC toxin complex from Yersinia entomophaga can package three different cytotoxic components expressed from distinct genetic loci in an unfolded state: the structures of both s... von Busby, Jason N, Trevelyan, Sarah, Pegg, Cassandra L, Kerr, Edward D, Schulz, Benjamin L, Chassagnon, Irene, Landsberg, Michael J, Weston, Mitchell K, Hurst, Mark R H, Lott, J Shaun

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Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin von Piper, Sarah J, Brillault, Lou, Rothnagel, Rosalba, Croll, Tristan I, Box, Joseph K, Chassagnon, Irene, Scherer, Sebastian, Goldie, Kenneth N, Jones, Sandra A, Schepers, Femke, Hartley-Tassell, Lauren, Ve, Thomas, Busby, Jason N, Dalziel, Julie E, Lott, J. Shaun, Hankamer, Ben, Stahlberg, Henning, Hurst, Mark R. H, Landsberg, Michael J

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