Doubling down with CAR-T cell cancer immunotherapy: a two-step recognition circuit enables discrimination between target antigen high and low cancer cells von Charo, Jehad, Gomes, Bruno

Volltext

Prediction of the Optimal Dosing Regimen Using a Mathematical Model of Tumor Uptake for Immunocytokine-Based Cancer Immunotherapy von Ribba, Benjamin, Boetsch, Christophe, Nayak, Tapan, Grimm, Hans Peter, Charo, Jehad, Evers, Stefan, Klein, Christian, Tessier, Jean, Charoin, Jean Eric, Phipps, Alex, Pisa, Pavel, Teichgräber, Volker

Volltext

Predictive biomarkers for PD-1/PD-L1 checkpoint inhibitor response in NSCLC: an analysis of clinical trial and real-world data von So, WeiQing Venus, Dejardin, David, Rossmann, Eva, Charo, Jehad

Volltext

Editorial: Biomarkers in the era of cancer immunotherapy: zooming in from the periphery to the tumor microenvironment von Charo, Jehad, Gomes, Bruno, Pietras, Kristian, Östman, Arne

Volltext

Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy von Waldhauer, Inja, Gonzalez-Nicolini, Valeria, Freimoser-Grundschober, Anne, Nayak, Tapan K., Fahrni, Linda, Hosse, Ralf J., Gerrits, Danny, Geven, Edwin J. W., Sam, Johannes, Lang, Sabine, Bommer, Esther, Steinhart, Virginie, Husar, Elisabeth, Colombetti, Sara, Van Puijenbroek, Erwin, Neubauer, Markus, Cline, J. Mark, Garg, Pradeep K., Dugan, Gregory, Cavallo, Federica, Acuna, Gonzalo, Charo, Jehad, Teichgraeber, Volker, Evers, Stefan, Boerman, Otto C., Bacac, Marina, Moessner, Ekkehard, Umana, Pablo, Klein, Christian

Volltext

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas von Kruschinski, Anna, Moosmann, Andreas, Poschke, Isabel, Norell, Håkan, Chmielewski, Markus, Seliger, Barbara, Kiessling, Rolf, Blankenstein, Thomas, Abken, Hinrich, Charo, Jehad

Volltext

Investigating the complex interplay between fibroblast activation protein α-positive cancer associated fibroblasts and the tumor microenvironment in the context of cancer immunothe... von Kraxner, Anton, Braun, Franziska, Cheng, Wei-Yi, Yang, Tai-Hsien Ou, Pipaliya, Shweta, Canamero, Marta, Andersson, Emilia, Harring, Suzana Vega, Dziadek, Sebastian, Bröske, Ann-Marie E, Ceppi, Maurizio, Tanos, Tamara, Teichgräber, Volker, Charo, Jehad

Volltext

Comprehensive analysis of fibroblast activation protein expression across 23 tumor indications: insights for biomarker development in cancer immunotherapies von Dziadek, Sebastian, Kraxner, Anton, Cheng, Wei-Yi, Ou Yang, Tai-Hsien, Flores, Mike, Theiss, Noah, Tsao, Tsu-Shuen, Andersson, Emilia, Harring, Suzana Vega, Bröske, Ann-Marie E, Ceppi, Maurizio, Teichgräber, Volker, Charo, Jehad

Volltext

safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer von Kieback, Elisa, Charo, Jehad, Sommermeyer, Daniel, Blankenstein, Thomas, Uckert, Wolfgang

Volltext

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope von Textor, Ana, Schmidt, Karin, Kloetzel, Peter-M, Weißbrich, Bianca, Perez, Cynthia, Charo, Jehad, Anders, Kathleen, Sidney, John, Sette, Alessandro, Schumacher, Ton N M, Keller, Christin, Busch, Dirk H, Seifert, Ulrike, Blankenstein, Thomas

Volltext

Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial von Norell, Håkan, Poschke, Isabel, Charo, Jehad, Wei, Wei Z, Erskine, Courtney, Piechocki, Marie P, Knutson, Keith L, Bergh, Jonas, Lidbrink, Elisabet, Kiessling, Rolf

Volltext

Correction: Preventing tumor escape by targeting a post-proteasomal trimming independent epitope von Textor, Ana, Schmidt, Karin, Kloetzel, Peter-M, Weißbrich, Bianca, Perez, Cynthia, Charo, Jehad, Anders, Kathleen, Sidney, John, Sette, Alessandro, Schumacher, Ton N M, Keller, Christin, Busch, Dirk H, Seifert, Ulrike, Blankenstein, Thomas

Volltext

930 Fibroblast activation protein alpha expression in tumor stroma and its association with immuno-regulatory circuits across epithelial tumors von Kraxner, Anton, Braun, Franziska, Cheng, Wei-Yi, Canamero, Marta, Andersson, Emilia, Harring, Suzana Vega, Dziadek, Sebastian, Broeske, Ann-Marie, Ceppi, Maurizio, Teichgraeber, Volker, Charo, Jehad

Volltext

Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines von Choudhury, Aniruddha, Charo, Jehad, Parapuram, Sunil K., Hunt, Richard C., Hunt, D. Margaret, Seliger, Barbara, Kiessling, Rolf

Volltext

HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice von Vertuani, Simona, Triulzi, Chiara, Roos, Anna Karin, Charo, Jehad, Norell, Håkan, Lemonnier, François, Pisa, Pavel, Seliger, Barbara, Kiessling, Rolf

Volltext

Protective Efficacy of a DNA Influenza Virus Vaccine Is Markedly Increased by the Coadministration of a Schiff Base-Forming Drug von CHARO, Jehad, LINDENCRONA, Jan Alvar, CARLSON, Lena-Maria, HINKULA, Jorma, KIESSLING, Rolf

Volltext

Targeting of Human Dendritic Cells by Autologous NK Cells von Wilson, Julia L, Heffler, Lena C, Charo, Jehad, Scheynius, Annika, Bejarano, Maria-Teresa, Ljunggren, Hans-Gustaf

Volltext

Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine von Roos, Anna-Karin, Pavlenko, Maxim, Charo, Jehad, Egevad, Lars, Pisa, Pavel

Volltext

Biomarkers in the era of cancer immunotherapy: zooming in from the periphery to the tumor microenvironment von Charo, J, Gomes, B, Pietras, K, Ostman, A

Volltext

Biomarker Technologies to Support Early Clinical Immuno-oncology Development: Advances and Interpretation von Cannarile, Michael A., Gomes, Bruno, Canamero, Marta, Reis, Bernhard, Byrd, Allyson, Charo, Jehad, Yadav, Mahesh, Karanikas, Vaios

Volltext