The Identification and Pharmacological Characterization of 6‑(tert-Butylsulfonyl)‑N‑(5-fluoro‑1H‑indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of... von Haile, Pamela A, Votta, Bartholomew J, Marquis, Robert W, Bury, Michael J, Mehlmann, John F, Singhaus, Robert, Charnley, Adam K, Lakdawala, Ami S, Convery, Máire A, Lipshutz, David B, Desai, Biva M, Swift, Barbara, Capriotti, Carol A, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Rivera, Elizabeth J, Sun, Helen H, Nagilla, Rakesh, Beal, Allison M, Finger, Joshua N, Cook, Michael N, King, Bryan W, Ouellette, Michael T, Totoritis, Rachel D, Pierdomenico, Maria, Negroni, Anna, Stronati, Laura, Cucchiara, Salvatore, Ziółkowski, Bartłomiej, Vossenkämper, Anna, MacDonald, Thomas T, Gough, Peter J, Bertin, John, Casillas, Linda N

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Diversity of locust gut bacteria protects against pathogen invasion von Dillon, R. J., Vennard, C. T., Buckling, A., Charnley, A. K.

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Introduction of automated breast ultrasound as an additional screening tool for dense breasts in the UK: a practical approach from the BRAID trial von Allajbeu, I., Morris, K., Nanaa, M., Payne, N., Charnley, K., Moyle, P.L., Taylor, K., Sharma, N., Lim, Y., Gilbert, F.J.

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Design of amidobenzimidazole STING receptor agonists with systemic activity von Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John

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note: Gut bacteria produce components of a locust cohesion pheromone von Dillon, R.J, Vennard, C.T, Charnley, A.K

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Pyrrolinone-Based Peptidomimetics.“Let the Enzyme or Receptor be the Judge” von Smith, Amos B, Charnley, Adam K, Hirschmann, Ralph

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Two-Dimensional Infrared Spectroscopy of Isotopomers of an Alanine Rich α-Helix von Fang, C, Wang, J, Kim, Y. S, Charnley, A. K, Barber-Armstrong, W, Smith, A. B, Decatur, S. M, Hochstrasser, R. M

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Composition of Acridid gut bacterial communities as revealed by 16S rRNA gene analysis von Dillon, R.J., Webster, G., Weightman, A.J., Dillon, V.M., Blanford, S., Charnley, A.K.

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The Role of Destruxins in the Pathogenicity of Metarhizium anisopliae for Three Species of Insect von Kershaw, M.J., Moorhouse, E.R., Bateman, R., Reynolds, S.E., Charnley, A.K.

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Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2‑((4-(Benzo[d]­thiazol-5-ylamino)-6‑(tert-butylsulfonyl)­quinazolin-7-yl)ox... von Haile, Pamela A, Casillas, Linda N, Votta, Bartholomew J, Wang, Gren Z, Charnley, Adam K, Dong, Xiaoyang, Bury, Michael J, Romano, Joseph J, Mehlmann, John F, King, Bryan W, Erhard, Karl F, Hanning, Charles R, Lipshutz, David B, Desai, Biva M, Capriotti, Carol A, Schaeffer, Michelle C, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Nagilla, Rakesh, Rivera, Elizabeth J, Sun, Helen H, Kenna, John K, Beal, Allison M, Ouellette, Michael T, Kelly, Mike, Stemp, Gillian, Convery, Máire A, Vossenkämper, Anna, MacDonald, Thomas T, Gough, Peter J, Bertin, John, Marquis, Robert W

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Two-dimensional infrared measurements of the coupling between amide modes of an α-helix von Fang, C., Wang, J., Charnley, A.K., Barber-Armstrong, W., Smith III, A.B., Decatur, S.M., Hochstrasser, R.M.

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The inhibitory effect of the fungal toxin, destruxin A, on behavioural fever in the desert locust von Hunt, V.L., Charnley, A.K.

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The immune response of the desert locust Schistocerca gregaria during mycosis of the entomopathogenic fungus, Metarhizium anisopliae var acridum von Gillespie, Jeremy P, Burnett, Claire, Charnley, A.Keith

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Design, Synthesis, and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors von Smith, Amos B, Cantin, Louis-David, Pasternak, Alexander, Guise-Zawacki, Lisa, Yao, Wenquin, Charnley, Adam K, Barbosa, Joseph, Sprengeler, Paul A, Hirschmann, Ralph, Munshi, Sanjeev, Olsen, David B, Schleif, William A, Kuo, Lawrence C

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Trehalose-hydrolysing enzymes of Metarhizium anisopliae and their role in pathogenesis of the tobacco hornworm, Manduca sexta von Xia, Y, Clarkson, J.M, Charnley, A.K

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Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity von Charnley, Adam K., Convery, Máire A., Lakdawala Shah, Ami, Jones, Emma, Hardwicke, Philip, Bridges, Angela, Ouellette, Michael, Totoritis, Rachel, Schwartz, Benjamin, King, Bryan W., Wisnoski, David D., Kang, James, Eidam, Patrick M., Votta, Bartholomew J., Gough, Peter J., Marquis, Robert W., Bertin, John, Casillas, Linda

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Effects of Lecanicillium longisporum infection on the behaviour of the green peach aphid Myzus persicae von Roditakis, Emmanouil, Couzin, Iain D., Franks, Nigel R., Charnley, Anthony K.

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Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors von Haffner, Curt D, Charnley, Adam K, Aquino, Christopher J, Casillas, Linda, Convery, Máire A, Cox, Julie A, Elban, Mark A, Goodwin, Nicole C, Gough, Peter J, Haile, Pamela A, Hughes, Terry V, Knapp-Reed, Beth, Kreatsoulas, Constantine, Lakdawala, Ami S, Li, Huijie, Lian, Yiqian, Lipshutz, David, Mehlmann, John F, Ouellette, Michael, Romano, Joseph, Shewchuk, Lisa, Shu, Arthur, Votta, Bartholomew J, Zhou, Huiqiang, Bertin, John, Marquis, Robert W

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Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity von Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John

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Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel von Haile, Pamela A, Casillas, Linda N, Bury, Michael J, Mehlmann, John F, Singhaus, Robert, Charnley, Adam K, Hughes, Terry V, DeMartino, Michael P, Wang, Gren Z, Romano, Joseph J, Dong, Xiaoyang, Plotnikov, Nikolay V, Lakdawala, Ami S, Convery, Maire A, Votta, Bartholomew J, Lipshutz, David B, Desai, Biva M, Swift, Barbara, Capriotti, Carol A, Berger, Scott B, Mahajan, Mukesh K, Reilly, Michael A, Rivera, Elizabeth J, Sun, Helen H, Nagilla, Rakesh, LePage, Carol, Ouellette, Michael T, Totoritis, Rachel D, Donovan, Brian T, Brown, Barry S, Chaudhary, Khuram W, Gough, Peter J, Bertin, John, Marquis, Robert W

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