The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance von Beltran, Himisha, Hruszkewycz, Andrew, Scher, Howard I, Hildesheim, Jeffrey, Isaacs, Jennifer, Yu, Evan Y, Kelly, Kathleen, Lin, Daniel, Dicker, Adam, Arnold, Julia, Hecht, Toby, Wicha, Max, Sears, Rosalie, Rowley, David, White, Richard, Gulley, James L, Lee, John, Diaz Meco, Maria, Small, Eric J, Shen, Michael, Knudsen, Karen, Goodrich, David W, Lotan, Tamara, Zoubeidi, Amina, Sawyers, Charles L, Rudin, Charles M, Loda, Massimo, Thompson, Timothy, Rubin, Mark A, Tawab-Amiri, Abdul, Dahut, William, Nelson, Peter S

Volltext

Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters von Tolstorukov, Michael Y., Sansam, Courtney G., Lu, Ping, Koellhoffer, Edward C., Helming, Katherine C., Alver, Burak H., Tillman, Erik J., Evans, Julia A., Wilson, Boris G., Park, Peter J., Roberts, Charles W. M.

Volltext

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment von Winter, Georg E., Mayer, Andreas, Buckley, Dennis L., Erb, Michael A., Roderick, Justine E., Vittori, Sarah, Reyes, Jaime M., di Iulio, Julia, Souza, Amanda, Ott, Christopher J., Roberts, Justin M., Zeid, Rhamy, Scott, Thomas G., Paulk, Joshiawa, Lachance, Kate, Olson, Calla M., Dastjerdi, Shiva, Bauer, Sophie, Lin, Charles Y., Gray, Nathanael S., Kelliher, Michelle A., Churchman, L. Stirling, Bradner, James E.

Volltext

The B.1.427/1.429 (epsilon) SARS-CoV-2 variants are more virulent than ancestral B.1 (614G) in Syrian hamsters von Carroll, Timothy, Fox, Douglas, van Doremalen, Neeltje, Ball, Erin, Morris, Mary Kate, Sotomayor-Gonzalez, Alicia, Servellita, Venice, Rustagi, Arjun, Yinda, Claude Kwe, Fritts, Linda, Port, Julia Rebecca, Ma, Zhong-Min, Holbrook, Myndi G, Schulz, Jonathan, Blish, Catherine A, Hanson, Carl, Chiu, Charles Y, Munster, Vincent, Stanley, Sarah, Miller, Christopher J

Volltext

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease von Eftekharzadeh, Bahareh, Daigle, J. Gavin, Kapinos, Larisa E., Coyne, Alyssa, Schiantarelli, Julia, Carlomagno, Yari, Cook, Casey, Miller, Sean J., Dujardin, Simon, Amaral, Ana S., Grima, Jonathan C., Bennett, Rachel E., Tepper, Katharina, DeTure, Michael, Vanderburg, Charles R., Corjuc, Bianca T., DeVos, Sarah L., Gonzalez, Jose Antonio, Chew, Jeannie, Vidensky, Svetlana, Gage, Fred H., Mertens, Jerome, Troncoso, Juan, Mandelkow, Eckhard, Salvatella, Xavier, Lim, Roderick Y.H., Petrucelli, Leonard, Wegmann, Susanne, Rothstein, Jeffrey D., Hyman, Bradley T.

Volltext

Large-scale features and evaluation of the PMIP4-CMIP6 midHolocene simulations von Brierley, Chris M., Zhao, Anni, Harrison, Sandy P., Braconnot, Pascale, Williams, Charles J. R., Thornalley, David J. R., Shi, Xiaoxu, Peterschmitt, Jean-Yves, Ohgaito, Rumi, Kaufman, Darrell S., Kageyama, Masa, Hargreaves, Julia C., Erb, Michael P., Emile-Geay, Julien, Agostino, Roberta D, Chandan, Deepak, Carré, Matthieu, Bartlein, Partrick J., Zheng, Weipeng, Zhang, Zhongshi, Zhang, Qiong, Yang, Hu, Volodin, Evgeny M., Tomas, Robert A., Routson, Cody, Peltier, W. Richard, Otto-Bliesner, Bette, Morozova, Polina A., McKay, Nicholas P., Lohmann, Gerrit, Legrande, Allegra N., Guo, Chuncheng, Cao, Jian, Brady, Esther, Annan, James D., Abe-Ouchi7, Ayako

Volltext

Single-cell analysis of human skin identifies CD14(+) type 3 dendritic cells co-producing IL1B and IL23A in psoriasis von Nakamizo, Satoshi, Dutertre, Charles-Antoine, Khalilnezhad, Ahad, Zhang, Xiao Meng, Lim, Shawn, Lum, Josephine, Koh, Geraldine, Foong, Charlene, Yong, Pearly Jean Ai, Tan, Kahbing Jasmine, Sato, Reiko, Tomari, Kaori, Yvan-Charvet, Laurent, He, Helen, Guttman-Yassky, Emma, Malleret, Benoit, Shibuya, Rintaro, Iwata, Masashi, Janela, Baptiste, Goto, Tsuyoshi, Lucinda, Tan Siyun, Tang, Mark B. Y., Theng, Colin, Julia, Valerie, Hacini-Rachinel, Feriel, Kabashima, Kenji, Ginhoux, Florent

Volltext

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein von Tuttle, Marcus D, Comellas, Gemma, Nieuwkoop, Andrew J, Covell, Dustin J, Berthold, Deborah A, Kloepper, Kathryn D, Courtney, Joseph M, Kim, Jae K, Barclay, Alexander M, Kendall, Amy, Wan, William, Stubbs, Gerald, Schwieters, Charles D, Lee, Virginia M Y, George, Julia M, Rienstra, Chad M

Volltext

Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study von Scher, Howard I, Prof, Beer, Tomasz M, MD, Higano, Celestia S, MD, Anand, Aseem, MA, Taplin, Mary-Ellen, MD, Efstathiou, Eleni, MD, Rathkopf, Dana, MD, Shelkey, Julia, BS, Yu, Evan Y, MD, Alumkal, Joshi, MD, Hung, David, MD, Hirmand, Mohammad, MD, Seely, Lynn, MD, Morris, Michael J, MD, Danila, Daniel C, MD, Humm, John, PhD, Larson, Steve, MD, Fleisher, Martin, PhD, Sawyers, Charles L, MD

Volltext

IL-1 beta-driven osteoclastogenic Tregs accelerate bone erosion in arthritis von Levescot, Anais, Chang, Margaret H., Schnell, Julia, Nelson-Maney, Nathan, Yan, Jing, Martinez-Bonet, Marta, Grieshaber-Bouyer, Ricardo, Lee, Pui Y., Wei, Kevin, Blaustein, Rachel B., Morris, Allyn, Wactor, Alexandra, Iwakura, Yoichiro, Lederer, James A., Rao, Deepak A., Charles, Julia F., Nigrovic, Peter A.

Volltext

When Ends Meet: Circular DNA Stretches Differently in Elongational Flows von Li, Yanfei, Hsiao, Kai-Wen, Brockman, Christopher A, Yates, Daniel Y, Robertson-Anderson, Rae M, Kornfield, Julia A, San Francisco, Michael J, Schroeder, Charles M, McKenna, Gregory B

Volltext

Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism von Zhu, Yihui, Gomez, J Antonio, Laufer, Benjamin I, Mordaunt, Charles E, Mouat, Julia S, Soto, Daniela C, Dennis, Megan Y, Benke, Kelly S, Bakulski, Kelly M, Dou, John, Marathe, Ria, Jianu, Julia M, Williams, Logan A, Gutierrez Fugón, Orangel J, Walker, Cheryl K, Ozonoff, Sally, Daniels, Jason, Grosvenor, Luke P, Volk, Heather E, Feinberg, Jason I, Fallin, M Daniele, Hertz-Picciotto, Irva, Schmidt, Rebecca J, Yasui, Dag H, LaSalle, Janine M

Volltext

Epidemiological and cohort study finds no association between COVID-19 and Guillain-Barré syndrome von Keddie, Stephen, Pakpoor, Julia, Mousele, Christina, Pipis, Menelaos, Machado, Pedro M, Foster, Mark, Record, Christopher J, Keh, Ryan Y S, Fehmi, Janev, Paterson, Ross W, Bharambe, Viraj, Clayton, Lisa M, Allen, Claire, Price, Olivia, Wall, Jasmine, Kiss-Csenki, Annamaria, Rathnasabapathi, Devi Priya, Geraldes, Ruth, Yermakova, Tatyana, King-Robson, Joshua, Zosmer, Maya, Rajakulendran, Sanjeev, Sumaria, Sheetal, Farmer, Simon F, Nortley, Ross, Marshall, Charles R, Newman, Edward J, Nirmalananthan, Niranjanan, Kumar, Guru, Pinto, Ashwin A, Holt, James, Lavin, Tim M, Brennan, Kathryn M, Zandi, Michael S, Jayaseelan, Dipa L, Pritchard, Jane, Hadden, Robert D M, Manji, Hadi, Willison, Hugh J, Rinaldi, Simon, Carr, Aisling S, Lunn, Michael P

Volltext

Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software von Sczyrba, Alexander, Hofmann, Peter, Belmann, Peter, Koslicki, David, Janssen, Stefan, Dröge, Johannes, Gregor, Ivan, Majda, Stephan, Fiedler, Jessika, Dahms, Eik, Bremges, Andreas, Fritz, Adrian, Garrido-Oter, Ruben, Jørgensen, Tue Sparholt, Shapiro, Nicole, Blood, Philip D, Gurevich, Alexey, Bai, Yang, Turaev, Dmitrij, DeMaere, Matthew Z, Chikhi, Rayan, Nagarajan, Niranjan, Quince, Christopher, Meyer, Fernando, Balvočiūtė, Monika, Hansen, Lars Hestbjerg, Sørensen, Søren J, Chia, Burton K H, Denis, Bertrand, Froula, Jeff L, Wang, Zhong, Egan, Robert, Don Kang, Dongwan, Cook, Jeffrey J, Deltel, Charles, Beckstette, Michael, Lemaitre, Claire, Peterlongo, Pierre, Rizk, Guillaume, Lavenier, Dominique, Wu, Yu-Wei, Singer, Steven W, Jain, Chirag, Strous, Marc, Klingenberg, Heiner, Meinicke, Peter, Barton, Michael D, Lingner, Thomas, Lin, Hsin-Hung, Liao, Yu-Chieh, Silva, Genivaldo Gueiros Z, Cuevas, Daniel A, Edwards, Robert A, Saha, Surya, Piro, Vitor C, Renard, Bernhard Y, Pop, Mihai, Klenk, Hans-Peter, Göker, Markus, Kyrpides, Nikos C, Woyke, Tanja, Vorholt, Julia A, Schulze-Lefert, Paul, Rubin, Edward M, Darling, Aaron E, Rattei, Thomas, McHardy, Alice C

Volltext

Cancer in People with and without Hepatitis C Virus Infection: Comparison of Risk Before and After Introduction of Direct-Acting Antivirals von Lam, Jennifer O., Hurley, Leo B., Lai, Jennifer B., Saxena, Varun, Seo, Suk, Chamberland, Scott, Quesenberry, Charles P., Champsi, Jamila H., Ready, Joanna, Chiao, Elizabeth Y., Marcus, Julia L., Silverberg, Michael J.

Volltext

mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome von Huang, Zhengping, You, Xiaomeng, Chen, Liang, Du, Yan, Brodeur, Kailey, Jee, Hyuk, Wang, Qiang, Linder, Grace, Darbousset, Roxane, Cunin, Pierre, Chang, Margaret H., Wactor, Alexandra, Wauford, Brian M., Todd, Marc J. C., Wei, Kevin, Li, Ying, Levescot, Anais, Iwakura, Yoichiro, Pascual, Virginia, Baldwin, Nicole E., Quartier, Pierre, Li, Tianwang, Gianatasio, Maria T., Hasserjian, Robert P., Henderson, Lauren A., Sykes, David B., Mellins, Elizabeth D., Canna, Scott W., Charles, Julia F., Nigrovic, Peter A., Lee, Pui Y.

Volltext

Freshwater salinization syndrome: from emerging global problem to managing risks von Kaushal, Sujay S., Likens, Gene E., Pace, Michael L., Reimer, Jenna E., Maas, Carly M., Galella, Joseph G., Utz, Ryan M., Duan, Shuiwang, Kryger, Julia R., Yaculak, Alexis M., Boger, Walter L., Bailey, Nathan W., Haq, Shahan, Wood, Kelsey L., Wessel, Barret M., Park, Cedric Evan, Collison, Daniel C., Aisin, Belie Y.’aaqob I., Gedeon, Taylor M., Chaudhary, Sona K., Widmer, Jacob, Blackwood, Charles R., Bolster, Claire M., Devilbiss, Matthew L., Garrison, Diego L., Halevi, Sharon, Kese, Gannon Q., Quach, Emily K., Rogelio, Christina M. P., Tan, Maggie L., Wald, Henry J. S., Woglo, Seyram A.

Volltext

Adeno-associated virus type 2 in US children with acute severe hepatitis von Servellita, Venice, Sotomayor Gonzalez, Alicia, Lamson, Daryl M., Foresythe, Abiodun, Huh, Hee Jae, Bazinet, Adam L., Bergman, Nicholas H., Bull, Robert L., Garcia, Karla Y., Goodrich, Jennifer S., Lovett, Sean P., Parker, Kisha, Radune, Diana, Hatada, April, Pan, Chao-Yang, Rizzo, Kyle, Bertumen, J. Bradford, Morales, Christina, Oluniyi, Paul E., Nguyen, Jenny, Tan, Jessica, Stryke, Doug, Jaber, Rayah, Leslie, Matthew T., Lyons, Zin, Hedman, Hayden D., Parashar, Umesh, Sullivan, Maureen, Wroblewski, Kelly, Oberste, M. Steven, Tate, Jacqueline E., Baker, Julia M., Sugerman, David, Potts, Caelin, Lu, Xiaoyan, Chhabra, Preeti, Ingram, L. Amanda, Shiau, Henry, Britt, William, Gutierrez Sanchez, Luz Helena, Ciric, Caroline, Rostad, Christina A., Vinjé, Jan, Kirking, Hannah L., Wadford, Debra A., Raborn, R. Taylor, St. George, Kirsten, Chiu, Charles Y.

Volltext

Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis von Leavitt, Tripp, Hu, Michael S., Borrelli, Mimi R., Januszyk, Michael, Garcia, Julia T., Ransom, Ryan C., Mascharak, Shamik, desJardins-Park, Heather E., Litzenburger, Ulrike M., Walmsley, Graham G., Marshall, Clement D., Moore, Alessandra L., Duoto, Bryan, Adem, Sandeep, Foster, Deshka S., Salhotra, Ankit, Shen, Abra H., Griffin, Michelle, Shen, Ethan Z., Barnes, Leandra A., Zielins, Elizabeth R., Maan, Zeshaan N., Wei, Yuning, Chan, Charles K.F., Wan, Derrick C., Lorenz, Hermann P., Chang, Howard Y., Gurtner, Geoffrey C., Longaker, Michael T.

Volltext

Effect of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy With Uterosacral Ligament Suspension on Treatment Failure in Women With Uterovaginal Prolapse: A Randomized Clinical Tria... von Nager, Charles W, Visco, Anthony G, Richter, Holly E, Rardin, Charles R, Rogers, Rebecca G, Harvie, Heidi S, Zyczynski, Halina M, Paraiso, Marie Fidela R, Mazloomdoost, Donna, Grey, Scott, Sridhar, Amaanti, Wallace, Dennis

Volltext