Discovery of Red-Shifting Mutations in Firefly Luciferase Using High-Throughput Biochemistry von Colee, Clair M., Oberlag, Nicole M., Simon, Marcell, Chapman, Owen S., Flanagan, Lyndsey C., Reid-McLaughlin, Edison S., Gewing-Mullins, Jordan A., Maiche, Synaida, Patel, Devi F., Cavalcanti, Andre R. O., Leconte, Aaron M.

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3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma von Okonechnikov, Konstantin, Camgöz, Aylin, Chapman, Owen, Wani, Sameena, Park, Donglim Esther, Hübner, Jens-Martin, Chakraborty, Abhijit, Pagadala, Meghana, Bump, Rosalind, Chandran, Sahaana, Kraft, Katerina, Acuna-Hidalgo, Rocio, Reid, Derek, Sikkink, Kristin, Mauermann, Monika, Juarez, Edwin F., Jenseit, Anne, Robinson, James T., Pajtler, Kristian W., Milde, Till, Jäger, Natalie, Fiesel, Petra, Morgan, Ling, Sridhar, Sunita, Coufal, Nicole G., Levy, Michael, Malicki, Denise, Hobbs, Charlotte, Kingsmore, Stephen, Nahas, Shareef, Snuderl, Matija, Crawford, John, Wechsler-Reya, Robert J., Davidson, Tom Belle, Cotter, Jennifer, Michaiel, George, Fleischhack, Gudrun, Mundlos, Stefan, Schmitt, Anthony, Carter, Hannah, Michealraj, Kulandaimanuvel Antony, Kumar, Sachin A., Taylor, Michael D., Rich, Jeremy, Buchholz, Frank, Mesirov, Jill P., Pfister, Stefan M., Ay, Ferhat, Dixon, Jesse R., Kool, Marcel, Chavez, Lukas

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Research-Creation: Intervention, Analysis and “Family Resemblances” von Chapman, Owen

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METB-01. EXTRACHROMOSOMAL DNA IS ASSOCIATED WITH ONCOGENE AMPLIFICATION AND POOR SURVIVAL ACROSS MULTIPLE PEDIATRIC CANCER TYPES von Sridhar, Sunita, Chapman, Owen, Dutta, Aditi, Wang, Shanqing, Chavez, Lukas

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PATH-31. ECDNA PROMOTES TUMORIGENICITY AND INTRATUMORAL HETEROGENEITY IN MEDULLOBLASTOMA von Chapman, Owen, Sridhar, Sunita, Wang, Shanqing, Mesirov, Jill, Chavez, Lukas

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EPCO-45. EXTRACHROMOSOMAL DNA PROMOTES ONCOGENE AMPLIFICATION ACROSS MULTIPLE PEDIATRIC CANCER TYPES von Sridhar, Sunita, Chapman, Owen, Dutta, Aditi, Wang, Shanqing, Chavez, Lukas

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Sounding Riddims: King Tubby’s dub in the context of soundscape composition von Yoganathan, Nimalan, Chapman, Owen

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MEDB-33. The landscape of ecDNA in medulloblastoma von Chapman, Owen, Sridhar, Sunita, Wang, Shanqing, Larson, Jon, Wechsler-Reya, Robert, Mesirov, Jill, Chavez, Lukas

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MEDB-66. Investigating intra-tumoral heterogeneity of extrachromosomal DNA in SHH medulloblastoma von Chapman, Owen, Sridhar, Sunita, Wechsler-Reya, Robert J, Chavez, Lukas, Mesirov, Jill P

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Creation-as-Research: Critical Making in Complex Environments von Chapman, Owen, Sawchuk, Kim

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Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression von Banerjee, Sourav, Wei, Tiantian, Wang, Jue, Lee, Jenna J., Gutierrez, Haydee L., Chapma, Owen, Wiley, Sandra E., Mayfield, Joshua E., Tandon, Vasudha, Juarez, Edwin F., Chavez, Lukas, Liang, Ruqi, Sah, Robert L., Costello, Caitlin, Mesirov, Jill P., de la Vega, Laureano, Cooper, Kimberly L., Dixon, Jack E., Xiao, Junyu, Lei, Xiaoguang

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MEDB-15. Dynamic chromatin alteration induces oncogenic hijacking by essential transcriptional factors during SHH medulloblastoma tumorigenesis von Shiraishi, Ryo, Cancila, Gabriele, Kumegawa, Kohei, da Silva, Patricia, Chapman, Owen, Wanchen, Wang, Jami, Maki, Hoshino, Mikio, Pfister, Stefan, Chavez, Lukas, Maruyama, Reo, Ayrault, Olivier, Kawauchi, Daisuke

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Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression von Shiraishi, Ryo, Cancila, Gabriele, Kumegawa, Kohei, Torrejon, Jacob, Basili, Irene, Bernardi, Flavia, Silva, Patricia Benites Goncalves da, Wang, Wanchen, Chapman, Owen, Yang, Liying, Jami, Maki, Nishitani, Kayo, Arai, Yukimi, Xiao, Zhize, Yu, Hua, Lo Re, Valentina, Marsaud, Véronique, Talbot, Julie, Lombard, Bérangère, Loew, Damarys, Jingu, Maho, Okonechnikov, Konstantin, Sone, Masaki, Motohashi, Norio, Aoki, Yoshitsugu, Pfister, Stefan M., Chavez, Lukas, Hoshino, Mikio, Maruyama, Reo, Ayrault, Olivier, Kawauchi, Daisuke

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Abstract 95: The landscape of extrachromosomal circular DNA in medulloblastoma subgroups von Chapman, Owen S., Wang, Shanqing, Luebeck, Jens, Garancher, Alexandra, Larson, Jon D., Lange, Joshua, Crawford, John, Pomeroy, Scott L., Mischel, Paul, Fraenkel, Ernest, Wechsler-Reya, Robert J., Bafna, Vineet, Mesirov, Jill P., Chavez, Lukas

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Abstract 447: Integrated omics modeling of transcriptional regulation in medulloblastoma subtypes von Chapman, Owen S., Ehrenberger, Tobias, Archer, Tenley C., Gold, Maxwell P., Mundt, Filip, Adam, Miriam, Mah, Clarence K., Krug, Karsten, Chandran, Sahaana, Dixon, Jesse R., Pomeroy, Scot L., Fraenkel, Ernest, Mesirov, Jill P., Chavez, Lukas

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The Elusive Allure of “Aura”: Sample-based Music and Benjamin’s Practice of Quotation von Chapman, Owen

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Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma von Chapman, Owen S., Luebeck, Jens, Sridhar, Sunita, Wong, Ivy Tsz-Lo, Dixit, Deobrat, Wang, Shanqing, Prasad, Gino, Rajkumar, Utkrisht, Pagadala, Meghana S., Larson, Jon D., He, Britney Jiayu, Hung, King L., Lange, Joshua T., Dehkordi, Siavash R., Chandran, Sahaana, Adam, Miriam, Morgan, Ling, Wani, Sameena, Tiwari, Ashutosh, Guccione, Caitlin, Lin, Yingxi, Dutta, Aditi, Lo, Yan Yuen, Juarez, Edwin, Robinson, James T., Korshunov, Andrey, Michaels, John-Edward A., Cho, Yoon-Jae, Malicki, Denise M., Coufal, Nicole G., Levy, Michael L., Hobbs, Charlotte, Scheuermann, Richard H., Crawford, John R., Pomeroy, Scott L., Rich, Jeremy N., Zhang, Xinlian, Chang, Howard Y., Dixon, Jesse R., Bagchi, Anindya, Deshpande, Aniruddha J., Carter, Hannah, Fraenkel, Ernest, Mischel, Paul S., Wechsler-Reya, Robert J., Bafna, Vineet, Mesirov, Jill P., Chavez, Lukas

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Abstract 6214: Detecting and characterizing extrachromosomal DNA in medulloblastoma at single-cell resolution von Chapman, Owen, Sridhar, Sunita, Larson, Jon D., Wechsler-Reya, Robert J., Mesirov, Jill, Chavez, Lukas

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Abstract 3886: 3D genome conformation analysis in ST-EPN-ZFTA ependymoma identifies RCOR2 as a potential target von Camgöz, Aylin, Okonechnikov, Konstantin, Chapman, Owen, Maurmann, Monika, Buchholz, Frank, Pfister, Stefan, Chavez, Lukas, Kool, Marcel

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OMIC-01. THE LANDSCAPE OF EXTRACHROMOSOMAL CIRCULAR DNA IN MEDULLOBLASTOMA SUBGROUPS von Chapman, Owen, Luebeck, Jens, Wang, Shanqing, Garancher, Alexandra, Larson, Jon, Lange, Joshua, Wong, Ivy Tsz Lo, Crawford, John, Pomeroy, Scott, Mischel, Paul, Fraenkel, Ernest, Wechsler-Reya, Robert, Bafna, Vineet, Mesirov, Jill, Chavez, Lukas

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