Anthrax Lethal Factor Inhibition von Shoop, W. L., Xiong, Y., Wiltsie, J., Woods, A., Guo, J., Pivnichny, J. V., Felcetto, T., Michael, B. F., Bansal, A., Cummings, R. T., Cunningham, B. R., Friedlander, A. M., Douglas, C. M., Patel, S. B., Wisniewski, D., Scapin, G., Salowe, S. P., Zaller, D. M., Chapman, K. T., Scolnick, E. M., Schmatz, D. M., Bartizal, K., MacCoss, M., Hermes, J. D., Campbell, William C.

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Directed reduction of .beta.-hydroxy ketones employing tetramethylammonium triacetoxyborohydride von Evans, D. A, Chapman, K. T, Carreira, E. M

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A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes von Thornberry, Nancy A, Bull, Herbert G, Calaycay, Jimmy R, Chapman, Kevin T, Howard, Andrew D, Kostura, Matthew J, Miller, Douglas K, Molineaux, Susan M, Weidner, Jeffrey R, Aunins, John, Elliston, Keith O, Ayala, Julia M, Casano, Francesca J, Chin, Jayne, Ding, Gloria J.-F, Egger, Linda A, Gaffney, Erin P, Limjuco, Guadalupe, Palyha, Oksana C, Raju, S. M, Rolando, Anna M, Salley, J. Paul, Yamin, Ting-Ting, Lee, Terry D, Shively, John E, MacCross, Malcolm, Mumford, Richard A, Schmidt, John A, Tocci, Michael J

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Inactivation of interleukin-1β converting enzyme by peptide (acyloxy)methyl ketones von THORNBERRY, N. A, PETERSON, E. P, ZHAO, J. J, HOWARD, A. D, GRIFFIN, P. R, CHAPMAN, K. T

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Asymmetric Diels-Alder cycloaddition reactions with chiral .alpha.,.beta.-unsaturated N-acyloxazolidinones von Evans, David A, Chapman, K. T, Bisaha, J

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Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry von Rohrer, Susan P., Birzin, Elizabeth T., Mosley, Ralph T., Berk, Scott C., Hutchins, Steven M., Shen, Dong-Ming, Xiong, Yusheng, Hayes, Edward C., Parmar, Rupa M., Foor, Forrest, Mitra, Sudha W., Degrado, Sylvia J., Shu, Min, Klopp, John M., Cai, Sheng-Jian, Blake, Allan, Wanda W. S. Chan, Pasternak, Alex, Yang, Lihu, Patchett, Arthur A., Smith, Roy G., Chapman, Kevin T., Schaeffer, James M.

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Dendrimer-Supported Combinatorial Chemistry von Kim, Ronald M., Manna, Mahua, Hutchins, Steven M., Griffin, Patrick R., Yates, Nathan A., Bernick, Amy M., Chapman, Kevin T.

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis von Thornberry, N A, Rano, T A, Peterson, E P, Rasper, D M, Timkey, T, Garcia-Calvo, M, Houtzager, V M, Nordstrom, P A, Roy, S, Vaillancourt, J P, Chapman, K T, Nicholson, D W

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New asymmetric Diels-Alder cycloaddition reactions. Chiral .alpha.,.beta.-unsaturated carboximides as practical chiral acrylate and crotonate dienophile synthons von Evans, D. A, Chapman, K. T, Bisaha, J

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Inhibition of matrix metalloproteinases by N-carboxyalkyl peptides von Chapman, Kevin T, Kopka, Ihor E, Durette, Philippe L, Esser, Craig K, Lanza, Thomas J, Izquierdo-Martin, Maria, Niedzwiecki, Lisa, Chang, Benedict, Harrison, Richard K

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Combinatorial diversification of indinavir: in vivo mixture dosing of an HIV protease inhibitor library von Rano, Thomas A, Cheng, Yuan, Huening, Tracy T, Zhang, Fengqi, Schleif, William A, Gabryelski, Lori, Olsen, David B, Kuo, Lawrence C, Lin, Jiunn H, Xu, Xin, Olah, Timothy V, McLoughlin, Debra A, King, Richard, Chapman, Kevin T, Tata, James R

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Versatile and Efficient Solid-Phase Syntheses of Pyrazoles and Isoxazoles von Shen, Dong-Ming, Shu, Min, Chapman, Kevin T

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Studies on the Kinetic and Chemical Mechanism of Inhibition of Stromelysin by an N-(Carboxyalkyl)dipeptide von Izquierdo-Martin, Maria, Chapman, K. T, Hagmann, W. K, Stein, Ross L

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[9] Determination of caspase specificities using a peptide combinatorial library von Thornberry, Nancy A., Chapman, Kevin T., Nicholson, Donald W.

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Combinatorial synthesis of CCR5 antagonists von Willoughby, Christopher A, Berk, Scott C, Rosauer, Keith G, Degrado, Silvia, Chapman, Kevin T, Gould, Sandra L, Springer, Martin S, Malkowitz, Lorraine, Schleif, William A, Hazuda, Daria, Miller, Michael, Kessler, Joseph, Danzeisen, Renee, Holmes, Karen, Lineberger, Janet, Carella, Anthony, Carver, Gwen, Emini, Emilio A

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Inhibition of Stromelysin-1 (MMP-3) by P1‘-Biphenylylethyl Carboxyalkyl Dipeptides von Esser, Craig K, Bugianesi, Robert L, Caldwell, Charles G, Chapman, Kevin T, Durette, Philippe L, Girotra, Narindar N, Kopka, Ihor E, Lanza, Thomas J, Levorse, Dorothy A, MacCoss, Malcolm, Owens, Karen A, Ponpipom, Mitree M, Simeone, Joseph P, Harrison, Richard K, Niedzwiecki, Lisa, Becker, Joseph W, Marcy, Alice I, Axel, Melinda G, Christen, Amy J, McDonnell, Joseph, Moore, Vernon L, Olszewski, Julie M, Saphos, Cheryl, Visco, Denise M, Shen, Frank, Colletti, Adria, Krieter, Philip A, Hagmann, William K

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A general method for the solid phase synthesis of ureas von Hutchins, Steven M., Chapman, Kevin T.

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Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial von Chapman, Kenneth R, Prof, Burdon, Jonathan G W, MD, Piitulainen, Eeva, MD, Sandhaus, Robert A, Prof, Seersholm, Niels, MD, Stocks, James M, MD, Stoel, Berend C, PhD, Huang, Liping, MD, Yao, Zhenling, MD, Edelman, Jonathan M, MD, McElvaney, Noel G, Prof

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The directed reduction of β-hydroxy ketones employing Me4NHB(OAc)3 von EVANS, D. A, CHAPMAN, K. T

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Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells von Miller, D.K., Ayala, J.M., Egger, L.A., Raju, S.M., Yamin, T.T., Ding, G.J., Gaffney, E.P., Howard, A.D., Palyha, O.C., Rolando, A.M.

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