Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease von Torres, Vicente E, Chapman, Arlene B, Devuyst, Olivier, Gansevoort, Ron T, Perrone, Ronald D, Koch, Gary, Ouyang, John, McQuade, Robert D, Blais, Jaime D, Czerwiec, Frank S, Sergeyeva, Olga

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Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease von Porath, Binu, Gainullin, Vladimir G., Cornec-Le Gall, Emilie, Dillinger, Elizabeth K., Heyer, Christina M., Hopp, Katharina, Edwards, Marie E., Madsen, Charles D., Mauritz, Sarah R., Banks, Carly J., Baheti, Saurabh, Reddy, Bharathi, Herrero, José Ignacio, Bañales, Jesús M., Hogan, Marie C., Tasic, Velibor, Watnick, Terry J., Chapman, Arlene B., Vigneau, Cécile, Lavainne, Frédéric, Audrézet, Marie-Pierre, Ferec, Claude, Le Meur, Yannick, Torres, Vicente E., Harris, Peter C.

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Blood Pressure in Early Autosomal Dominant Polycystic Kidney Disease von Schrier, Robert W, Abebe, Kaleab Z, Perrone, Ronald D, Torres, Vicente E, Braun, William E, Steinman, Theodore I, Winklhofer, Franz T, Brosnahan, Godela, Czarnecki, Peter G, Hogan, Marie C, Miskulin, Dana C, Rahbari-Oskoui, Frederic F, Grantham, Jared J, Harris, Peter C, Flessner, Michael F, Bae, Kyongtae T, Moore, Charity G, Chapman, Arlene B

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Angiotensin Blockade in Late Autosomal Dominant Polycystic Kidney Disease von Torres, Vicente E, Abebe, Kaleab Z, Chapman, Arlene B, Schrier, Robert W, Braun, William E, Steinman, Theodore I, Winklhofer, Franz T, Brosnahan, Godela, Czarnecki, Peter G, Hogan, Marie C, Miskulin, Dana C, Rahbari-Oskoui, Frederic F, Grantham, Jared J, Harris, Peter C, Flessner, Michael F, Moore, Charity G, Perrone, Ronald D

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Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease von Nowak, Kristen L, You, Zhiying, Gitomer, Berenice, Brosnahan, Godela, Torres, Vicente E, Chapman, Arlene B, Perrone, Ronald D, Steinman, Theodore I, Abebe, Kaleab Z, Rahbari-Oskoui, Frederic F, Yu, Alan S L, Harris, Peter C, Bae, Kyongtae T, Hogan, Marie, Miskulin, Dana, Chonchol, Michel

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Approaches to Testing New Treatments in Autosomal Dominant Polycystic Kidney Disease: Insights from the CRISP and HALT-PKD Studies von Chapman, Arlene B

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Effect of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease by CKD Stage: Results from the TEMPO 3:4 Trial von Torres, Vicente E, Higashihara, Eiji, Devuyst, Olivier, Chapman, Arlene B, Gansevoort, Ronald T, Grantham, Jared J, Perrone, Ronald D, Ouyang, John, Blais, Jaime D, Czerwiec, Frank S

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Plasma copeptin levels predict disease progression and tolvaptan efficacy in autosomal dominant polycystic kidney disease von Gansevoort, Ron T., van Gastel, Maatje D.A., Chapman, Arlene B., Blais, Jaime D., Czerwiec, Frank S., Higashihara, Eiji, Lee, Jennifer, Ouyang, John, Perrone, Ronald D., Stade, Katrin, Torres, Vicente E., Devuyst, Olivier

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Urine Osmolality, Response to Tolvaptan, and Outcome in Autosomal Dominant Polycystic Kidney Disease: Results from the TEMPO 3:4 Trial von Devuyst, Olivier, Chapman, Arlene B, Gansevoort, Ron T, Higashihara, Eiji, Perrone, Ronald D, Torres, Vicente E, Blais, Jaime D, Zhou, Wen, Ouyang, John, Czerwiec, Frank S

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Kidney Volume and Functional Outcomes in Autosomal Dominant Polycystic Kidney Disease von Chapman, Arlene B, Bost, James E, Torres, Vicente E, Guay-Woodford, Lisa, Bae, Kyongtae Ty, Landsittel, Douglas, Li, Jie, King, Bernard F, Martin, Diego, Wetzel, Louis H, Lockhart, Mark E, Harris, Peter C, Moxey-Mims, Marva, Flessner, Mike, Bennett, William M, Grantham, Jared J

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Development of the Autosomal Dominant Polycystic Kidney Disease Impact Scale: A New Health-Related Quality-of-Life Instrument von Oberdhan, Dorothee, Cole, Jason C., Krasa, Holly B., Cheng, Rebecca, Czerwiec, Frank S., Hays, Ron D., Chapman, Arlene B., Perrone, Ronald D.

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Polycystins, ADPKD, and Cardiovascular Disease von Kuo, Ivana Y., Chapman, Arlene B.

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Dietary salt restriction is beneficial to the management of autosomal dominant polycystic kidney disease von Torres, Vicente E., Abebe, Kaleab Z., Schrier, Robert W., Perrone, Ronald D., Chapman, Arlene B., Yu, Alan S., Braun, William E., Steinman, Theodore I., Brosnahan, Godela, Hogan, Marie C., Rahbari, Frederic F., Grantham, Jared J., Bae, Kyongtae T., Moore, Charity G., Flessner, Michael F.

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Rationale and Design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes) 3-4 Study von Torres, Vicente E., MD, PhD, Meijer, Esther, MD, Bae, Kyongtae T., MD, PhD, Chapman, Arlene B., MD, Devuyst, Olivier, MD, PhD, Gansevoort, Ron T., MD, PhD, Grantham, Jared J., MD, Higashihara, Eiji, MD, Perrone, Ronald D., MD, Krasa, Holly B., MS, Ouyang, John J., PhD, Czerwiec, Frank S., MD, PhD

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Pharmacokinetics and Pharmacodynamics of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: Phase 2 Trials for Dose Selection in the Pivotal Phase 3 Trial von Shoaf, Susan E., Chapman, Arlene B., Torres, Vicente E., Ouyang, John, Czerwiec, Frank S.

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Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: Three Years' Experience von Higashihara, Eiji, Torres, Vicente E, Chapman, Arlene B, Grantham, Jared J, Bae, Kyongtae, Watnick, Terry J, Horie, Shigeo, Nutahara, Kikuo, Ouyang, John, Krasa, Holly B, Czerwiec, Frank S

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Volume Progression in Autosomal Dominant Polycystic Kidney Disease: The Major Factor Determining Clinical Outcomes von Grantham, Jared J, Chapman, Arlene B, Torres, Vicente E

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A novel simple method for determining CYP2D6 gene copy number and identifying allele(s) with duplication/multiplication von Langaee, Taimour, Hamadeh, Issam, Chapman, Arlene B, Gums, John G, Johnson, Julie A

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Albuminuria and tolvaptan in autosomal-dominant polycystic kidney disease: results of the TEMPO 3:4 Trial von Gansevoort, Ron T, Meijer, Esther, Chapman, Arlene B, Czerwiec, Frank S, Devuyst, Olivier, Grantham, Jared J, Higashihara, Eiji, Krasa, Holly B, Ouyang, John, Perrone, Ronald D, Torres, Vicente E

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Can we further enrich autosomal dominant polycystic kidney disease clinical trials for rapidly progressive patients? Application of the PROPKD score in the TEMPO trial von Cornec-Le Gall, Emilie, Blais, Jaime D, Irazabal, Maria V, Devuyst, Olivier, Gansevoort, Ron T, Perrone, Ron D, Chapman, Arlene B, Czerwiec, Frank S, Ouyang, John, Heyer, Christina M, Senum, Sarah R, Le Meur, Yannick, Torres, Vicente E, Harris, Peter C

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