APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology von Tran, Kristine M, Kwang, Nellie E, Butler, Claire A, Gomez-Arboledas, Angela, Kawauchi, Shimako, Mar, Cassandra, Chao, Donna, Barahona, Rocio A, Da Cunha, Celia, Tsourmas, Kate I, Shi, Zechuan, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai-Xuan, Alcantara, Joshua A, Neumann, Jonathan, Duong, Duc M, Seyfried, Nicholas T, Tenner, Andrea J, LaFerla, Frank M, Hohsfield, Lindsay A, Swarup, Vivek, MacGregor, Grant R, Green, Kim N

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Differential effects of Apoe Christchurch (R136S) mutation on amyloid plaque and tau pathology in transgenic mouse models von Tran, Kristine M, Kawauchi, Shimako, Kwang, Nellie, Mar, Cassandra, Chao, Donna, Da Cunha, Celia, Tenner, Andrea J, LaFerla, Frank M, MacGregor, Grant R, Green, Kim N.

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Basic Science and Pathogenesis von Tran, Kristine M, Kawauchi, Shimako, Kwang, Nellie, Mar, Cassandra, Chao, Donna, Da Cunha, Celia, Tenner, Andrea J, LaFerla, Frank M, MacGregor, Grant R, Green, Kim N

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Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumo... von Li, Yangbing, Yang, Jiuling, Aguilar, Angelo, McEachern, Donna, Przybranowski, Sally, Liu, Liu, Yang, Chao-Yie, Wang, Mi, Han, Xin, Wang, Shaomeng

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Transmission event of SARS-CoV-2 delta variant reveals multiple vaccine breakthrough infections von Farinholt, Timothy, Doddapaneni, Harsha, Qin, Xiang, Menon, Vipin, Meng, Qingchang, Metcalf, Ginger, Chao, Hsu, Gingras, Marie-Claude, Avadhanula, Vasanthi, Farinholt, Paige, Agrawal, Charu, Muzny, Donna M, Piedra, Pedro A, Gibbs, Richard A, Petrosino, Joseph

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ClinVar: improving access to variant interpretations and supporting evidence von Landrum, Melissa J, Lee, Jennifer M, Benson, Mark, Brown, Garth R, Chao, Chen, Chitipiralla, Shanmuga, Gu, Baoshan, Hart, Jennifer, Hoffman, Douglas, Jang, Wonhee, Karapetyan, Karen, Katz, Kenneth, Liu, Chunlei, Maddipatla, Zenith, Malheiro, Adriana, McDaniel, Kurt, Ovetsky, Michael, Riley, George, Zhou, George, Holmes, J Bradley, Kattman, Brandi L, Maglott, Donna R

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ClinVar: public archive of interpretations of clinically relevant variants von Landrum, Melissa J, Lee, Jennifer M, Benson, Mark, Brown, Garth, Chao, Chen, Chitipiralla, Shanmuga, Gu, Baoshan, Hart, Jennifer, Hoffman, Douglas, Hoover, Jeffrey, Jang, Wonhee, Katz, Kenneth, Ovetsky, Michael, Riley, George, Sethi, Amanjeev, Tully, Ray, Villamarin-Salomon, Ricardo, Rubinstein, Wendy, Maglott, Donna R

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Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity von Zhou, Haibin, Lu, Jianfeng, Chinnaswamy, Krishnapriya, Stuckey, Jeanne A., Liu, Liu, McEachern, Donna, Yang, Chao-Yie, Bernard, Denzil, Shen, Hong, Rui, Liangyou, Sun, Yi, Wang, Shaomeng

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Mixed linear model approach adapted for genome-wide association studies von Zhang, Zhiwu, Ersoz, Elhan, Lai, Chao-Qiang, Todhunter, Rory J, Tiwari, Hemant K, Gore, Michael A, Bradbury, Peter J, Yu, Jianming, Arnett, Donna K, Ordovas, Jose M, Buckler, Edward S

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Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Induc... von Qin, Chong, Hu, Yang, Zhou, Bing, Fernandez-Salas, Ester, Yang, Chao-Yie, Liu, Liu, McEachern, Donna, Przybranowski, Sally, Wang, Mi, Stuckey, Jeanne, Meagher, Jennifer, Bai, Longchuan, Chen, Zhuo, Lin, Mei, Yang, Jiuling, Ziazadeh, Danya N, Xu, Fuming, Hu, Jiantao, Xiang, Weiguo, Huang, Liyue, Li, Siwei, Wen, Bo, Sun, Duxin, Wang, Shaomeng

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Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein von Zhou, Haibin, Bai, Longchuan, Xu, Renqi, Zhao, Yujun, Chen, Jianyong, McEachern, Donna, Chinnaswamy, Krishnapriya, Wen, Bo, Dai, Lipeng, Kumar, Praveen, Yang, Chao-Yie, Liu, Zhaomin, Wang, Mi, Liu, Liu, Meagher, Jennifer L, Yi, Han, Sun, Duxin, Stuckey, Jeanne A, Wang, Shaomeng

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ClinVar: improvements to accessing data von Landrum, Melissa J, Chitipiralla, Shanmuga, Brown, Garth R, Chen, Chao, Gu, Baoshan, Hart, Jennifer, Hoffman, Douglas, Jang, Wonhee, Kaur, Kuljeet, Liu, Chunlei, Lyoshin, Vitaly, Maddipatla, Zenith, Maiti, Rama, Mitchell, Joseph, O’Leary, Nuala, Riley, George R, Shi, Wenyao, Zhou, George, Schneider, Valerie, Maglott, Donna, Holmes, J Bradley, Kattman, Brandi L

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MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease von Satishchandran, Abhishek, Ambade, Aditya, Rao, Sitara, Hsueh, Ying-Chao, Iracheta-Vellve, Arvin, Tornai, David, Lowe, Patrick, Gyongyosi, Benedek, Li, Jia, Catalano, Donna, Zhong, Li, Kodys, Karen, Xie, Jun, Bala, Shashi, Gao, Guangping, Szabo, Gyongyi

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Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression von Zhou, Bing, Hu, Jiantao, Xu, Fuming, Chen, Zhuo, Bai, Longchuan, Fernandez-Salas, Ester, Lin, Mei, Liu, Liu, Yang, Chao-Yie, Zhao, Yujun, McEachern, Donna, Przybranowski, Sally, Wen, Bo, Sun, Duxin, Wang, Shaomeng

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A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo von Bai, Longchuan, Zhou, Haibin, Xu, Renqi, Zhao, Yujun, Chinnaswamy, Krishnapriya, McEachern, Donna, Chen, Jianyong, Yang, Chao-Yie, Liu, Zhaomin, Wang, Mi, Liu, Liu, Jiang, Hui, Wen, Bo, Kumar, Praveen, Meagher, Jennifer L., Sun, Duxin, Stuckey, Jeanne A., Wang, Shaomeng

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Estimating the natural indirect effect and the mediation proportion via the product method von Cheng, Chao, Spiegelman, Donna, Li, Fan

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Is the Product Method More Efficient Than the Difference Method for Assessing Mediation? von Cheng, Chao, Spiegelman, Donna, Li, Fan

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Mediation analysis in the presence of continuous exposure measurement error von Cheng, Chao, Spiegelman, Donna, Li, Fan

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Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer von Bai, Longchuan, Zhou, Bing, Yang, Chao-Yie, Ji, Jiao, McEachern, Donna, Przybranowski, Sally, Jiang, Hui, Hu, Jiantao, Xu, Fuming, Zhao, Yujun, Liu, Liu, Fernandez-Salas, Ester, Xu, Jing, Dou, Yali, Wen, Bo, Sun, Duxin, Meagher, Jennifer, Stuckey, Jeanne, Hayes, Daniel F, Li, Shunqiang, Ellis, Matthew J, Wang, Shaomeng

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Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication von Shinbrot, Eve, Henninger, Erin E, Weinhold, Nils, Covington, Kyle R, Göksenin, A Yasemin, Schultz, Nikolaus, Chao, Hsu, Doddapaneni, HarshaVardhan, Muzny, Donna M, Gibbs, Richard A, Sander, Chris, Pursell, Zachary F, Wheeler, David A

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