Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces von Lee, Myungjin, Changela, Anita, Gorman, Jason, Rawi, Reda, Bylund, Tatsiana, Chao, Cara W., Lin, Bob C., Louder, Mark K., Olia, Adam S., Zhang, Baoshan, Doria-Rose, Nicole A., Zolla-Pazner, Susan, Shapiro, Lawrence, Chuang, Gwo-Yu, Kwong, Peter D.

Volltext

Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV von Chao, Cara W., Sprouse, Kaitlin R., Miranda, Marcos C., Catanzaro, Nicholas J., Hubbard, Miranda L., Addetia, Amin, Stewart, Cameron, Brown, Jack T., Dosey, Annie, Valdez, Adian, Ravichandran, Rashmi, Hendricks, Grace G., Ahlrichs, Maggie, Dobbins, Craig, Hand, Alexis, McGowan, Jackson, Simmons, Boston, Treichel, Catherine, Willoughby, Isabelle, Walls, Alexandra C., McGuire, Andrew T., Leaf, Elizabeth M., Baric, Ralph S., Schäfer, Alexandra, Veesler, David, King, Neil P.

Volltext

Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life von Zhang, Baoshan, Gollapudi, Deepika, Gorman, Jason, O’Dell, Sijy, Damron, Leland F., McKee, Krisha, Asokan, Mangaiarkarasi, Yang, Eun Sung, Pegu, Amarendra, Lin, Bob C., Chao, Cara W., Chen, Xuejun, Gama, Lucio, Ivleva, Vera B., Law, William H., Liu, Cuiping, Louder, Mark K., Schmidt, Stephen D., Shen, Chen-Hsiang, Shi, Wei, Stein, Judith A., Seaman, Michael S., McDermott, Adrian B., Carlton, Kevin, Mascola, John R., Kwong, Peter D., Lei, Q. Paula, Doria-Rose, Nicole A.

Volltext

Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency von Zhang, Baoshan, Gorman, Jason, Kwon, Young D, Pegu, Amarendra, Chao, Cara W, Liu, Tracy, Asokan, Mangaiarkarasi, Bender, Michael F, Bylund, Tatsiana, Damron, Leland, Gollapudi, Deepika, Lei, Paula, Li, Yile, Liu, Cuiping, Louder, Mark K, McKee, Krisha, Olia, Adam S, Rawi, Reda, Schön, Arne, Wang, Shuishu, Yang, Eun Sung, Yang, Yongping, Carlton, Kevin, Doria-Rose, Nicole A, Shapiro, Lawrence, Seaman, Michael S, Mascola, John R, Kwong, Peter D

Volltext

A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spik... von Zhang, Baoshan, Chao, Cara W., Tsybovsky, Yaroslav, Abiona, Olubukola M., Hutchinson, Geoffrey B., Moliva, Juan I., Olia, Adam S., Pegu, Amarendra, Phung, Emily, Stewart-Jones, Guillaume B. E., Verardi, Raffaello, Wang, Lingshu, Wang, Shuishu, Werner, Anne, Yang, Eun Sung, Yap, Christina, Zhou, Tongqing, Mascola, John R., Sullivan, Nancy J., Graham, Barney S., Corbett, Kizzmekia S., Kwong, Peter D.

Volltext

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles von Li, Ze, Li, Wenwei, Lu, Maolin, Bess, Julian, Chao, Cara W., Gorman, Jason, Terry, Daniel S., Zhang, Baoshan, Zhou, Tongqing, Blanchard, Scott C., Kwong, Peter D., Lifson, Jeffrey D., Mothes, Walther, Liu, Jun

Volltext

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization von Kong, Rui, Duan, Hongying, Sheng, Zizhang, Xu, Kai, Acharya, Priyamvada, Chen, Xuejun, Cheng, Cheng, Dingens, Adam S., Gorman, Jason, Sastry, Mallika, Shen, Chen-Hsiang, Zhang, Baoshan, Zhou, Tongqing, Chuang, Gwo-Yu, Chao, Cara W., Gu, Ying, Jafari, Alexander J., Louder, Mark K., O’Dell, Sijy, Rowshan, Ariana P., Viox, Elise G., Wang, Yiran, Choi, Chang W., Corcoran, Martin M., Corrigan, Angela R., Dandey, Venkata P., Eng, Edward T., Geng, Hui, Foulds, Kathryn E., Guo, Yicheng, Kwon, Young D., Lin, Bob, Liu, Kevin, Mason, Rosemarie D., Nason, Martha C., Ohr, Tiffany Y., Ou, Li, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Todd, John P., Wang, Shuishu, Wei, Hui, Wu, Winston, Mullikin, James C., Bailer, Robert T., Doria-Rose, Nicole A., Karlsson Hedestam, Gunilla B., Scorpio, Diana G., Overbaugh, Julie, Bloom, Jesse D., Carragher, Bridget, Potter, Clinton S., Shapiro, Lawrence, Kwong, Peter D., Mascola, John R.

Volltext

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth von Roark, Ryan S, Li, Hui, Williams, Wilton B, Chug, Hema, Mason, Rosemarie D, Gorman, Jason, Wang, Shuyi, Lee, Fang-Hua, Rando, Juliette, Bonsignori, Mattia, Hwang, Kwan-Ki, Saunders, Kevin O, Wiehe, Kevin, Moody, M Anthony, Hraber, Peter T, Wagh, Kshitij, Giorgi, Elena E, Russell, Ronnie M, Bibollet-Ruche, Frederic, Liu, Weimin, Connell, Jesse, Smith, Andrew G, DeVoto, Julia, Murphy, Alexander I, Smith, Jessica, Ding, Wenge, Zhao, Chengyan, Chohan, Neha, Okumura, Maho, Rosario, Christina, Ding, Yu, Lindemuth, Emily, Bauer, Anya M, Bar, Katharine J, Ambrozak, David, Chao, Cara W, Chuang, Gwo-Yu, Geng, Hui, Lin, Bob C, Louder, Mark K, Nguyen, Richard, Zhang, Baoshan, Lewis, Mark G, Raymond, Donald D, Doria-Rose, Nicole A, Schramm, Chaim A, Douek, Daniel C, Roederer, Mario, Kepler, Thomas B, Kelsoe, Garnett, Mascola, John R, Kwong, Peter D, Korber, Bette T, Harrison, Stephen C, Haynes, Barton F, Hahn, Beatrice H, Shaw, George M

Volltext

Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody von Madan, Bharat, Zhang, Baoshan, Xu, Kai, Chao, Cara W., O’Dell, Sijy, Wolfe, Jacy R., Chuang, Gwo-Yu, Fahad, Ahmed S., Geng, Hui, Kong, Rui, Louder, Mark K., Nguyen, Thuy Duong, Rawi, Reda, Schön, Arne, Sheng, Zizhang, Nimrania, Rajani, Wang, Yiran, Zhou, Tongqing, Lin, Bob C., Doria-Rose, Nicole A., Shapiro, Lawrence, Kwong, Peter D., DeKosky, Brandon J.

Volltext

Cholesterol reduction by immunization with a PCSK9 mimic von Zhang, Baoshan, Chuang, Gwo-Yu, Biju, Andrea, Biner, Daniel, Cheng, Jiaxuan, Wang, Yiran, Bao, Saran, Chao, Cara W., Lei, Haotian, Liu, Tracy, Nazzari, Alexandra F., Yang, Yongping, Zhou, Tongqing, Chen, Steven J., Chen, Xuejun, Kong, Wing-Pui, Ou, Li, Parchment, Danealle K., Sarfo, Edward K., SiMa, HaoMin, Todd, John-Paul, Wang, Shuishu, Woodward, Ruth A., Cheng, Cheng, Rawi, Reda, Mascola, John R., Kwong, Peter D.

Volltext

VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage von Shen, Chen-Hsiang, DeKosky, Brandon J., Guo, Yicheng, Xu, Kai, Gu, Ying, Kilam, Divya, Ko, Sung Hee, Kong, Rui, Liu, Kevin, Louder, Mark K., Ou, Li, Zhang, Baoshan, Chao, Cara W., Corcoran, Martin M., Feng, Eric, Huang, Jesse, Normandin, Erica, O’Dell, Sijy, Ransier, Amy, Rawi, Reda, Sastry, Mallika, Schmidt, Stephen D., Wang, Shuishu, Wang, Yiran, Chuang, Gwo-Yu, Doria-Rose, Nicole A., Lin, Bob, Zhou, Tongqing, Boritz, Eli A., Connors, Mark, Douek, Daniel C., Karlsson Hedestam, Gunilla B., Sheng, Zizhang, Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.

Volltext

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen von Ou, Li, Kong, Wing-Pui, Chuang, Gwo-Yu, Ghosh, Mridul, Gulla, Krishana, O’Dell, Sijy, Varriale, Joseph, Barefoot, Nathan, Changela, Anita, Chao, Cara W., Cheng, Cheng, Druz, Aliaksandr, Kong, Rui, McKee, Krisha, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Shaddeau, Andrew, Tsybovsky, Yaroslav, Verardi, Raffaello, Wang, Shuishu, Wanninger, Timothy G., Xu, Kai, Yang, Gengcheng J., Zhang, Baoshan, Zhang, Yaqiu, Zhou, Tongqing, Arnold, Frank J., Doria-Rose, Nicole A., Lei, Q. Paula, Ryan, Edward T., Vann, Willie F., Mascola, John R., Kwong, Peter D.

Volltext

Sub-Nanometer Structures of HIV-1 Envelope Trimers on Aldrithiol-2 Inactivated Virus Particles von Li, Ze, Li, Wenwei, Lu, Maolin, Bess, Julian, Chao, Cara W., Gorman, Jay, Terry, Daniel S., Zhang, Baoshan, Zhou, Tongqing, Blanchard, Scott C., Kwong, Peter D., Lifson, Jeffrey D., Mothes, Walther, Liu, Jun

Volltext

VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing von Shen, C-H, DeKosky, BJ, Guo, Y, Xu, K, Gu, Y, Kilam, D, Ko, SH, Kong, R, Liu, K, Louder, MK

Volltext

VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage von Shen, Chen-Hsiang, DeKosky, Brandon J., Guo, Yicheng, Xu, Kai, Gu, Ying, Kilam, Divya, Ko, Sung Hee, Kong, Rui, Liu, Kevin, Louder, Mark K., Ou, Li, Zhang, Baoshan, Chao, Cara W., Corcoran, Martin M., Feng, Eric, Huang, Jesse, Normandin, Erica, O’Dell, Sijy, Ransier, Amy, Rawi, Reda, Sastry, Mallika, Schmidt, Stephen D., Wang, Shuishu, Wang, Yiran, Chuang, Gwo-Yu, Doria-Rose, Nicole A., Lin, Bob, Zhou, Tongqing, Boritz, Eli A., Connors, Mark, Douek, Daniel C., Karlsson Hedestam, Gunilla B., Sheng, Zizhang, Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.

Volltext

Discovery of a stem-like multipotent cell fate von Paffhausen, Emily S, Alowais, Yasir, Chao, Cara W, Callihan, Evan C, Creswell, Karen, Bracht, John R

Volltext

HIV-1 Env fusion peptide nanoparticle carrier conjugates and their use von Zhang, Baoshan, Wang, Yiran, Chao, Cara W, Kwong, Peter, Ou, Li, Tsybovsky, Yaroslav, Mascola, John, Kong, Wing-Pui, Boyington, Jeffrey, Xu, Kai

Volltext bestellen

Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency von Zhang, Baoshan, Gorman, Jason, Kwon, Young D., Pegu, Amarendra, Chao, Cara W., Liu, Tracy, Asokan, Mangaiarkarasi, Bender, Michael F., Bylund, Tatsiana, Damron, Leland, Gollapudi, Deepika, Lei, Paula, Li, Yile, Liu, Cuiping, Louder, Mark K., McKee, Krisha, Olia, Adam S., Rawi, Reda, Schön, Arne, Wang, Shuishu, Yang, Eun Sung, Yang, Yongping, Carlton, Kevin, Doria-Rose, Nicole A., Shapiro, Lawrence, Seaman, Michael S., Mascola, John R., Kwong, Peter D.

Volltext

HIV-1 ENV FUSION PEPTIDE NANOPARTICLE CARRIER CONJUGATES AND THEIR USE von Zhang, Baoshan, Wang, Yiran, Chao, Cara W, Kwong, Peter, Ou, Li, Tsybovsky, Yaroslav, Mascola, John, Kong, Wing-Pui, Boyington, Jeffrey, Xu, Kai

Volltext bestellen

HIV-1 ENV FUSION PEPTIDE NANOPARTICLE CARRIER CONJUGATES AND THEIR USE von KWONG, Peter, OU, Li, ZHANG, Baoshan, TSYBOVSKY, Yaroslav, CHAO, Cara W, MASCOLA, John, KONG, Wing-Pui, XU, Kai

Volltext bestellen