Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis von Brahmamdam, Pavan, Inoue, Shigeaki, Unsinger, Jacqueline, Chang, Katherine C., McDunn, Jonathan E., Hotchkiss, Richard S.

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Blockade ofthe negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis von Chang, Katherine C, Burnham, Carey-Ann, Compton, Stephanie M, Rasche, David P, Mazuski, RichardJ, SMcDonough, Jacquelyn, Unsinger, Jacqueline, Korman, Alan J, Green, Jonathan M, Hotchkiss, Richard S

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Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site von Xu, Jinbin, Zeng, Chenbo, Chu, Wenhua, Pan, Fenghui, Rothfuss, Justin M., Zhang, Fanjie, Tu, Zhude, Zhou, Dong, Zeng, Dexing, Vangveravong, Suwanna, Johnston, Fabian, Spitzer, Dirk, Chang, Katherine C., Hotchkiss, Richard S., Hawkins, William G., Wheeler, Kenneth T., Mach, Robert H.

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Accelerated Lymphocyte Death in Sepsis Occurs by both the Death Receptor and Mitochondrial Pathways von Hotchkiss, Richard S, Osmon, Stephen B, Chang, Katherine C, Wagner, Tracey H, Coopersmith, Craig M, Karl, Irene E

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Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis von Chang, Katherine C, Unsinger, Jacqueline, Davis, Christopher G, Schwulst, Steven J, Muenzer, Jared T, Strasser, Andreas, Hotchkiss, Richard S

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Anti-PD-L1 peptide improves survival in sepsis von Shindo, Yuichiro, McDonough, Jacquelyn S., Chang, Katherine C., Ramachandra, Murali, Sasikumar, Pottayil G., Hotchkiss, Richard S.

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Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival von Peck‐Palmer, Octavia M., Unsinger, Jacqueline, Chang, Katherine C., Davis, Christopher G., McDunn, Jonathan E., Hotchkiss, Richard S.

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Sepsis Induces Apoptosis and Profound Depletion of Splenic Interdigitating and Follicular Dendritic Cells von Tinsley, Kevin W, Grayson, Mitchell H, Swanson, Paul E, Drewry, Anne M, Chang, Katherine C, Karl, Irene E, Hotchkiss, Richard S

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Adoptive Transfer of Apoptotic Splenocytes Worsens Survival, Whereas Adoptive Transfer of Necrotic Splenocytes Improves Survival in Sepsis von Hotchkiss, Richard S., Chang, Katherine C., Grayson, Mitchell H., Tinsley, Kevin W., Dunne, Benjamin S., Davis, Christopher G., Osborne, Dale F., Karl, Irene E.

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Overexpression of Bcl-2 in Transgenic Mice Decreases Apoptosis and Improves Survival in Sepsis von Hotchkiss, Richard S, Swanson, Paul E, Knudson, C. Michael, Chang, Katherine C, Cobb, J. Perren, Osborne, Dale F, Zollner, Kimberly M, Buchman, Timothy G, Korsmeyer, Stanley J, Karl, Irene E

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Akt Decreases Lymphocyte Apoptosis and Improves Survival in Sepsis von Bommhardt, Ursula, Chang, Katherine C, Swanson, Paul E, Wagner, Tracey H, Tinsley, Kevin W, Karl, Irene E, Hotchkiss, Richard S

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Characterization and Evaluation of Two Novel Fluorescent Sigma-2 Receptor Ligands as Proliferation Probes von Zeng, Chenbo, Vangveravong, Suwanna, Jones, Lynne A., Hyrc, Krzysztof, Chang, Katherine C., Xu, Jinbin, Rothfuss, Justin M., Goldberg, Mark P., Hotchkiss, Richard S., Mach, Robert H.

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Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis von Schwulst, Steven J, Muenzer, Jared T, Peck-Palmer, Octavia M, Chang, Katherine C, Davis, Christopher G, McDonough, Jacquelyn S, Osborne, Dale F, Walton, Andrew H, Unsinger, Jacqueline, McDunn, Jonathan E, Hotchkiss, Richard S

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Targeted delivery of siRNA to cell death proteins in sepsis von Brahmamdam, Pavan, Watanabe, Eizo, Unsinger, Jacqueline, Chang, Katherine C, Schierding, William, Hoekzema, Andrew S, Zhou, Tony T, McDonough, Jacquelyn S, Holemon, Heather, Heidel, Jeremy D, Coopersmith, Craig M, McDunn, Jonathan E, Hotchkiss, Richard S

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Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice von Coopersmith, Craig M, Chang, Katherine C, Swanson, Paul E, Tinsley, Kevin W, Stromberg, Paul E, Buchman, Timothy G, Karl, Irene E, Hotchkiss, Richard S

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Peptide-mediated activation of Akt and extracellular regulated kinase signaling prevents lymphocyte apoptosis von McDunn, Jonathan E, Muenzer, Jared T, Rachdi, Latif, Chang, Katherine C, Davis, Chris G, Dunne, W. Michael, Piwnica-Worms, David, Bernal-Mizrachi, Ernesto, Hotchkiss, Richard S

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Sepsis-Induced Apoptosis Causes Progressive Profound Depletion of B and CD4+ T Lymphocytes in Humans von Hotchkiss, Richard S, Tinsley, Kevin W, Swanson, Paul E, Schmieg, Robert E., Jr, Hui, Jia Ji, Chang, Katherine C, Osborne, Dale F, Freeman, Bradley D, Cobb, J. Perren, Buchman, Timothy G, Karl, Irene E

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Subcellular localization of Sigma-2 receptors in breast cancer cells using two-photon and confocal microscopy von CHENBO ZENG, VANGVERAVONG, Suwanna, JINBIN XU, CHANG, Katherine C, HOTCHKISS, Richard S, WHEELER, Kenneth T, DUANWEN SHEN, ZHUANG, Zhi-Ping, KUNG, Hank F, MACH, Robert H

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Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis von FOX, Amy C, ROBERTSON, Charles M, BUCHMAN, Timothy G, LINEHAN, David C, COOPERSMITH, Craig M, BELT, Brian, CLARK, Andrew T, CHANG, Katherine C, LEATHERSICH, Ann M, DOMINGUEZ, Jessica A, PERRONE, Erin E, DUNNE, W. Michael, HOTCHKISS, Richard S

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TAT-BH4 and TAT-Bcl-xL Peptides Protect against Sepsis-Induced Lymphocyte Apoptosis In Vivo von Hotchkiss, Richard S, McConnell, Kevin W, Bullok, Kristin, Davis, Christopher G, Chang, Katherine C, Schwulst, Steven J, Dunne, Jeffrey C, Dietz, Gunnar P. H, Bahr, Mathias, McDunn, Jonathan E, Karl, Irene E, Wagner, Tracey H, Cobb, J. Perren, Coopersmith, Craig M, Piwnica-Worms, David

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