Genetic Redirection of T Cells for the Treatment of Pancreatic Cancer von Ali, Aesha I, Oliver, Amanda J, Samiei, Tinaz, Chan, Jack D, Kershaw, Michael H, Slaney, Clare Y

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity von House, Imran G., Derrick, Emily B., Sek, Kevin, Chen, Amanda X.Y., Li, Jasmine, Lai, Junyun, Todd, Kirsten L., Munoz, Isabelle, Michie, Jessica, Chan, Cheok Weng, Huang, Yu-Kuan, Chan, Jack D., Petley, Emma V., Tong, Junming, Nguyen, DatMinh, Engel, Sven, Savas, Peter, Hogg, Simon J., Vervoort, Stephin J., Kearney, Conor J., Burr, Marian L., Lam, Enid Y.N., Gilan, Omer, Bedoui, Sammy, Johnstone, Ricky W., Dawson, Mark A., Loi, Sherene, Darcy, Phillip K., Beavis, Paul A.

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Cellular networks controlling T cell persistence in adoptive cell therapy von Chan, Jack D., Lai, Junyun, Slaney, Clare Y., Kallies, Axel, Beavis, Paul A., Darcy, Phillip K.

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Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity von Lai, Junyun, Mardiana, Sherly, House, Imran G., Sek, Kevin, Henderson, Melissa A., Giuffrida, Lauren, Chen, Amanda X. Y., Todd, Kirsten L., Petley, Emma V., Chan, Jack D., Carrington, Emma M., Lew, Andrew M., Solomon, Benjamin J., Trapani, Joseph A., Kedzierska, Katherine, Evrard, Maximilien, Vervoort, Stephin J., Waithman, Jason, Darcy, Phillip K., Beavis, Paul A.

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Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells von Chan, Jack D, Scheidt, Bianca, Zeng, Bijun, Oliver, Amanda J, Davey, Ashleigh S, Ali, Aesha I, Thomas, Ranjeny, Trapani, Joseph A, Darcy, Phillip K, Kershaw, Michael H, Dolcetti, Riccardo, Slaney, Clare Y

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Tissue‐specific tumor microenvironments influence responses to immunotherapies von Oliver, Amanda J, Davey, Ashleigh S, Keam, Simon P, Mardiana, Sherly, Chan, Jack D, Scheidt, Bianca, Beavis, Paul A, House, Imran G, Van Audernaerde, Jonas RM, Darcy, Phillip K, Kershaw, Michael H, Slaney, Clare Y

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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy von Chan, Jack D., Scheffler, Christina M., Munoz, Isabelle, Sek, Kevin, Lee, Joel N., Huang, Yu-Kuan, Yap, Kah Min, Saw, Nicole Y. L., Li, Jasmine, Chen, Amanda X. Y., Chan, Cheok Weng, Derrick, Emily B., Todd, Kirsten L., Tong, Junming, Dunbar, Phoebe A., Li, Jiawen, Hoang, Thang X., de Menezes, Maria N., Petley, Emma V., Kim, Joelle S., Nguyen, Dat, Leung, Patrick S. K., So, Joan, Deguit, Christian, Zhu, Joe, House, Imran G., Kats, Lev M., Scott, Andrew M., Solomon, Benjamin J., Harrison, Simon J., Oliaro, Jane, Parish, Ian A., Quinn, Kylie M., Neeson, Paul J., Slaney, Clare Y., Lai, Junyun, Beavis, Paul A., Darcy, Phillip K.

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p38 Kinase: A Key Target for Driving Potent T Cells for Adoptive Immunotherapy von Chan, Jack D., Beavis, Paul A., Darcy, Phillip K.

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A Histone Deacetylase Inhibitor, Panobinostat, Enhances Chimeric Antigen Receptor T-cell Antitumor Effect Against Pancreatic Cancer von Ali, Aesha I, Wang, Minyu, von Scheidt, Bianca, Dominguez, Pilar M, Harrison, Aaron J, Tantalo, Daniela G M, Kang, Jian, Oliver, Amanda J, Chan, Jack D, Du, Xin, Bai, Yuchen, Lee, Belinda, Johnstone, Ricky W, Darcy, Phillip K, Kershaw, Michael H, Slaney, Clare Y

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MAIT cells regulate NK cell-mediated tumor immunity von Petley, Emma V., Koay, Hui-Fern, Henderson, Melissa A., Sek, Kevin, Todd, Kirsten L., Keam, Simon P., Lai, Junyun, House, Imran G., Li, Jasmine, Zethoven, Magnus, Chen, Amanda X. Y., Oliver, Amanda J., Michie, Jessica, Freeman, Andrew J., Giuffrida, Lauren, Chan, Jack D., Pizzolla, Angela, Mak, Jeffrey Y. W., McCulloch, Timothy R., Souza-Fonseca-Guimaraes, Fernando, Kearney, Conor J., Millen, Rosemary, Ramsay, Robert G., Huntington, Nicholas D., McCluskey, James, Oliaro, Jane, Fairlie, David P., Neeson, Paul J., Godfrey, Dale I., Beavis, Paul A., Darcy, Phillip K.

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Enterotoxins can support CAR T cells against solid tumors von von Scheidt, Bianca, Wang, Minyu, Oliver, Amanda J., Chan, Jack D., Jana, Metta K., Ali, Aesha I., Clow, Fiona, Fraser, John D., Quinn, Kylie M., Darcy, Phillip K., Kershaw, Michael H., Slaney, Clare Y.

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity von House, Imran G., Derrick, Emily B., Sek, Kevin, Chen, Amanda X.Y., Li, Jasmine, Lai, Junyun, Todd, Kirsten L., Munoz, Isabelle, Michie, Jessica, Chan, Cheok Weng, Huang, Yu-Kuan, Chan, Jack D., Petley, Emma V., Tong, Junming, Nguyen, DatMinh, Engel, Sven, Savas, Peter, Hogg, Simon J., Vervoort, Stephin J., Kearney, Conor J., Burr, Marian L., Lam, Enid Y.N., Gilan, Omer, Bedoui, Sammy, Johnstone, Ricky W., Dawson, Mark A., Loi, Sherene, Darcy, Phillip K., Beavis, Paul A.

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Chimeric antigen receptor T cell therapies for thoracic cancers— challenges and opportunities von Chan, Jack D., Harrison, Aaron J., Darcy, Phillip K., Kershaw, Michael H., Slaney, Clare Y.

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A Rare Cell State Underpins Diverse Mechanisms of Adaptive Resistance to CAR T-Cell Therapy in B-Cell Acute Lymphoblastic Leukemia von Kuzich, James A, Talarmain, Laure, Vassiliadis, Dane, Guirguis, Andrew A, Chan, Jack D, Beavis, Paul A, Darcy, Phillip K, Ng, Ashley P, Dawson, Mark A

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Cellular networks controlling T cell persistence in adoptive cell therapy von Chan, Jack D, Lai, Junyun, Slaney, Clare Y, Kallies, Axel, Beavis, Paul A, Darcy, Phillip K

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Nucleolar RNA polymerase II drives ribosome biogenesis von Abraham, Karan J., Khosraviani, Negin, Chan, Janet N. Y., Gorthi, Aparna, Samman, Anas, Zhao, Dorothy Y., Wang, Miling, Bokros, Michael, Vidya, Elva, Ostrowski, Lauren A., Oshidari, Roxanne, Pietrobon, Violena, Patel, Parasvi S., Algouneh, Arash, Singhania, Rajat, Liu, Yupeng, Yerlici, V. Talya, De Carvalho, Daniel D., Ohh, Michael, Dickson, Brendan C., Hakem, Razq, Greenblatt, Jack F., Lee, Stephen, Bishop, Alexander J. R., Mekhail, Karim

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A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women von Joura, Elmar A, Giuliano, Anna R, Iversen, Ole-Erik, Bouchard, Celine, Mao, Constance, Mehlsen, Jesper, Moreira, Edson D, Ngan, Yuen, Petersen, Lone Kjeld, Lazcano-Ponce, Eduardo, Pitisuttithum, Punnee, Restrepo, Jaime Alberto, Stuart, Gavin, Woelber, Linn, Yang, Yuh Cheng, Cuzick, Jack, Garland, Suzanne M, Huh, Warner, Kjaer, Susanne K, Bautista, Oliver M, Chan, Ivan S.F, Chen, Joshua, Gesser, Richard, Moeller, Erin, Ritter, Michael, Vuocolo, Scott, Luxembourg, Alain

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Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer von Liao, Zhongxing, Lee, J Jack, Komaki, Ritsuko, Gomez, Daniel R, O'Reilly, Michael S, Fossella, Frank V, Blumenschein, Jr, George R, Heymach, John V, Vaporciyan, Ara A, Swisher, Stephen G, Allen, Pamela K, Choi, Noah Chan, DeLaney, Thomas F, Hahn, Stephen M, Cox, James D, Lu, Charles S, Mohan, Radhe

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Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors von Kaatz, Scott, Kouides, Peter A., Garcia, David A., Spyropolous, Alex C., Crowther, Mark, Douketis, Jim D., Chan, Anthony K. C., James, Andra, Moll, Stephan, Ortel, Thomas L., Van Cott, Elizabeth M., Ansell, Jack

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cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity von Zhao, Yunlong, Caron, Christine, Chan, Ya-Yuan, Lee, Calvin K., Xu, Xiaozheng, Zhang, Jibin, Masubuchi, Takeya, Wu, Chuan, Bui, Jack D., Hui, Enfu

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