Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis von Mo, Yulan, Leung, Leanne L, Mak, Celia S L, Wang, Xueyu, Chan, Wai-Sun, Hui, Lynn M N, Tang, Hermit W M, Siu, Michelle K Y, Sharma, Rakesh, Xu, Dakang, Tsui, Stephen K W, Ngan, Hextan Y S, Yung, Mingo M H, Chan, Karen K L, Chan, David W

Volltext

CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer von Li, Enhao, Yang, Xiaobao, Du, Yuzhang, Wang, Guanzheng, David W Chan, Wu, Di, Xu, Peiqing, Ni, Peihua, Xu, Dakang, Hu, Yiqun

Volltext

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells von Chan, David W., Liu, Vincent W.S., Tsao, George S.W., Yao, Kwok-Ming, Furukawa, Toru, Chan, Karen K.L., Ngan, Hextan Y.S.

Volltext

Orchestrated Action of AMPK Activation and Combined VEGF/PD-1 Blockade with Lipid Metabolic Tunning as Multi-Target Therapeutics against Ovarian Cancers von Yung, Mingo M. H., Siu, Michelle K. Y., Ngan, Hextan Y. S., Chan, David W., Chan, Karen K. L.

Volltext

New Insights into Ferroptosis Initiating Therapies (FIT) by Targeting the Rewired Lipid Metabolism in Ovarian Cancer Peritoneal Metastases von Zhan, Shijie, Yung, Mingo M H, Siu, Michelle K Y, Jiao, Peili, Ngan, Hextan Y S, Chan, David W, Chan, Karen K L

Volltext

Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells von Lok, Gabriel T M, Chan, David W, Liu, Vincent W S, Hui, Winnie W Y, Leung, Thomas H Y, Yao, K M, Ngan, Hextan Y S

Volltext

p53 Promotes chemoresponsiveness by regulating hexokinase II gene transcription and metabolic reprogramming in epithelial ovarian cancer von Han, Chae Young, Patten, David A., Lee, Seung Gee, Parks, Robin J., Chan, David W., Harper, Mary‐Ellen, Tsang, Benjamin K.

Volltext

PFKFB3 Regulates Chemoresistance, Metastasis and Stemness via IAP Proteins and the NF-κB Signaling Pathway in Ovarian Cancer von Jiang, Yu-Xin, Siu, Michelle K Y, Wang, Jing-Jing, Leung, Thomas H Y, Chan, David W, Cheung, Annie N Y, Ngan, Hextan Y S, Chan, Karen K L

Volltext

DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer von Meng, Yunxiao, Chen, Chi-Wei, Yung, Mingo M.H., Sun, Wei, Sun, Jing, Li, Zhuqing, Li, Jing, Li, Zongzhu, Zhou, Wei, Liu, Stephanie S., Cheung, Annie N.Y., Ngan, Hextan Y.S., Braisted, John C., Kai, Yan, Peng, Weiqun, Tzatsos, Alexandros, Li, Yiliang, Dai, Zhijun, Zheng, Wei, Chan, David W., Zhu, Wenge

Volltext

Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC von Dong, Danfeng, Du, Yuzhang, Fei, Xuefeng, Yang, Hao, Li, Xiaofang, Yang, Xiaobao, Ma, Junrui, Huang, Shu, Ma, Zhihui, Zheng, Juanjuan, Chan, David W., Shi, Liyun, Li, Yunqi, Irving, Aaron T., Yuan, Xiangliang, Liu, Xiangfan, Ni, Peihua, Hu, Yiqun, Meng, Guangxun, Peng, Yibing, Sadler, Anthony, Xu, Dakang

Volltext

SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells von Xuan, Yang, Wang, Huogang, Yung, Mingo Mh, Chen, Fushun, Chan, Wai-Sun, Chan, Yau-Sang, Tsui, Stephen Kw, Ngan, Hextan Ys, Chan, Karen Kl, Chan, David W

Volltext

Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells von Chan, David W, Hui, Winnie W Y, Cai, Patty C H, Liu, Michelle X, Yung, Mingo M H, Mak, Celia S L, Leung, Thomas H Y, Chan, Karen K L, Ngan, Hextan Y S

Volltext

Epigenetic Silencing of miR-33b Promotes Peritoneal Metastases of Ovarian Cancer by Modulating the TAK1/FASN/CPT1A/NF-kappa B Axis von Wang, Xueyu, Yung, Mingo M. H., Sharma, Rakesh, Chen, Fushun, Poon, Ying-Tung, Lam, Wai-Yip, Li, Benjamin, Ngan, Hextan Y. S., Chan, Karen K. L., Chan, David W. W.

Volltext

Aberrant upregulation of PDK1 in ovarian cancer cells impairs CD8+ T cell function and survival through elevation of PD-L1 von Wang, Jing-Jing, Siu, Michelle K., Jiang, Yu-Xin, Leung, Thomas H., Chan, David W., Cheng, Ran-Ran, Cheung, Annie N., Ngan, Hextan Y., Chan, Karen K.

Volltext

AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity von Kwan, H T, Chan, David W, Cai, Patty C H, Mak, Celia S L, Yung, Mingo M H, Leung, Thomas H Y, Wong, Oscar G W, Cheung, Annie N Y, Ngan, Hextan Y S

Volltext

Polyunsaturated fatty acids promote M2-like TAM deposition via dampening RhoA-YAP1 signaling in the ovarian cancer microenvironment von Wang, Huogang, Yung, Mingo Mh, Xuan, Yang, Chen, Fushun, Chan, Waisun, Siu, Michelle Ky, Long, Runying, Jia, Shuo, Liang, Yonghao, Xu, Dakang, Song, Zhangfa, Tsui, Stephen Kw, Ngan, Hextan Ys, Chan, Karen Kl, Chan, David W

Volltext

Regeneration of 200 Gbit/s PAM4 Signal Produced by Silicon Microring Modulator (SiMRM) Using Mach–Zehnder Interferometer (MZI)-Based Optical Neural Network (ONN) von Hung, Tun-Yao, Chan, David W. U, Peng, Ching-Wei, Chow, Chi-Wai, Tsang, Hon Ki

Volltext

Increased expression of PITX2 transcription factor contributes to ovarian cancer progression von Fung, Frederic K C, Chan, David W, Liu, Vincent W S, Leung, Thomas H Y, Cheung, Annie N Y, Ngan, Hextan Y S

Volltext

Subjective well-being of Hong Kong Chinese teachers: The contribution of gratitude, forgiveness, and the orientations to happiness von Chan, David W.

Volltext

The Impact of the Tumor Microenvironment on Macrophage Polarization in Cancer Metastatic Progression von Wang, Huogang, Yung, Mingo M. H., Ngan, Hextan Y. S., Chan, Karen K. L., Chan, David W.

Volltext