12380 Point Of Care Microscale Magnetic Resonance (µNMR) Effectively Monitors Mitigation Of Oxidative Stress By GLP-1 Treatment In A Preclinical Model Of Diabetic Nephropathy von Alves, Andre Topa, Thamarath, Smitha Surendran, Fjordside, Simone, Sassower, Stan, Rohr, Rodolfo, Chambers, Adam Paul

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12362 Pathophysiology From Oxidative Stress Effectively Monitored In A Pre-clinical Model Of Type 2 Diabetes (T2D) With Point-of-care Microscale Magnetic Resonance (µNMR) von Alves, Andre Topa, Thamarath, Smitha Surendran, Fjordside, Simone, Sassower, Stan, Han, Jongyoon, Bouchard, Louis, Rohr, Rodolfo, Chambers, Adam Paul

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Compounds for treatment of obesity von Bloch, Paw, Chambers, Adam Paul, Roed, Nikolaj Kulahin, Sandrini, Michael Paolo Bastner, Knudsen, Lotte Bjerre, Lau, Jesper, Secher, Anna, McGuire, Jim

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NOVEL COMPOUNDS FOR TREATMENT OF OBESITY von ROED, Nikolaj, Kulahin, LAU, Jesper, KNUDSEN, Lotte Bjerre, SECHER, Anna, BLOCH, Paw, MCGUIRE, Jim, SANDRINI, Michael, Paolo, Bastner, CHAMBERS, Adam, Paul

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NOVEL COMPOUNDS FOR TREATMENT OF OBESITY von Bloch, Paw, Chambers, Adam Paul, Roed, Nikolaj Kulahin, Sandrini, Michael Paolo Bastner, Knudsen, Lotte Bjerre, Lau, Jesper, Secher, Anna, McGuire, Jim

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NOVEL COMPOUNDS FOR TREATMENT OF OBESITY von ROED, Nikolaj, Kulahin, LAU, Jesper, KNUDSEN, Lotte Bjerre, SECHER, Anna, BLOCH, Paw, MCGUIRE, Jim, SANDRINI, Michael, Paolo, Bastner, CHAMBERS, Adam, Paul

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NOVEL COMPOUNDS FOR TREATMENT OF OBESITY von CHAMBERS ADAM, BLOCH PAW, ROED NIKOLAJ K, CHAMBERS ADAM PAUL, MCGUIRE JIM, RAUH JULIA, SANDRINI MICHAEL P B, L. B. KNUDSEN

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DOSING REGIMEN FOR WEIGHT LOSS von KOOPMANS HENRY SJOERD, SHARKEY KEITH ALEXANDER, CHAMBERS ADAM PAUL

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DOSING REGIMEN FOR WEIGHT LOSS von CHAMBERS, ADAM, PAUL, SHARKEY, KEITH, ALEXANDER, KOOPMANS, HENRY, SJOERD

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METHOD FOR APPETITE SUPPRESSION von KOOPMANS, HENRY SJOERD, SHARKEY, KEITH ALEXANDER, CHAMBERS, ADAM PAUL

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Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions von Teixeira, Vitor H., Pipinikas, Christodoulos P., Pennycuick, Adam, Lee-Six, Henry, Chandrasekharan, Deepak, Beane, Jennifer, Morris, Tiffany J., Karpathakis, Anna, Feber, Andrew, Breeze, Charles E., Ntolios, Paschalis, Hynds, Robert E., Falzon, Mary, Capitanio, Arrigo, Carroll, Bernadette, Durrenberger, Pascal F., Hardavella, Georgia, Brown, James M., Lynch, Andy G., Farmery, Henry, Paul, Dirk S., Chambers, Rachel C., McGranahan, Nicholas, Navani, Neal, Thakrar, Ricky M., Swanton, Charles, Beck, Stephan, George, Phillip Jeremy, Spira, Avrum, Campbell, Peter J., Thirlwell, Christina, Janes, Sam M.

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The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis von Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.

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The Effects of Vertical Sleeve Gastrectomy in Rodents Are Ghrelin Independent von Chambers, Adam P, Kirchner, Henriette, Wilson–Perez, Hilary E, Willency, Jill A, Hale, John E, Gaylinn, Bruce D, Thorner, Michael O, Pfluger, Paul T, Gutierrez, Jesus A, Tschöp, Matthias H, Sandoval, Darleen A, Seeley, Randy J

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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes von Chauhan, Ganesh, Traylor, Matthew, Sargurupremraj, Muralidharan, Okada, Yukinori, Mishra, Aniket, Giese, Anne-Katrin, van der Laan, Sander W., Gretarsdottir, Solveig, Anderson, Christopher D., Almgren, Peter, Amouyel, Philippe, Bartz, Traci M., Benavente, Oscar R., Boncoraglio, Giorgio B., Butterworth, Adam S., Carrera, Caty, Chasman, Daniel I., Cotlarciuc, Ioana, Cruchaga, Carlos, de Bakker, Paul I. W., Duan, Qing, Gottesman, Rebecca F., Harris, Tamara B., Hassan, Ahamad, Havulinna, Aki S., Heckbert, Susan R., Hyacinth, Hyacinth I., Ikram, M. Arfan, Ingelsson, Erik, Jian, Xueqiu, Jukema, J. Wouter, Kanai, Masahiro, Keene, Keith L., Kissela, Brett M., Kleindorfer, Dawn O., Kooperberg, Charles, Lange, Leslie A., Langenberg, Claudia, Launer, Lenore J., Lemmens, Robin, Lewis, Cathryn M., Lin, Wei-Yu, Lorentzen, Erik, Magnusson, Patrik K., Meschia, James F., Mitchell, Braxton D., Mosley, Thomas H., Nalls, Michael A., O’Donnell, Martin J., Pulit, Sara L., Reiner, Alexander P., Ridker, Paul M., Rothwell, Peter M., Rotter, Jerome I., Sale, Michele M., Salomaa, Veikko, Sapkota, Bishwa R., Schmidt, Reinhold, Schmidt, Carsten O., Sharma, Pankaj, Slowik, Agnieszka, Sudlow, Cathie L. M., Tanislav, Christian, Thijs, Vincent N. S., Thorsteinsdottir, Unnur, Tiedt, Steffen, Trompet, Stella, Wareham, Nicholas J., Wassertheil-Smoller, Sylvia, Wilson, James G., Pastinen, Tomi, Ruusalepp, Arno, Koplev, Simon, Björkegren, Johan L. M., Codoni, Veronica, Civelek, Mete, Christophersen, Ingrid E., Roselli, Carolina, Ellinor, Patrick T., Kato, Norihiro, van der Harst, Pim, Elliott, Paul, Takeuchi, Fumihiko, Johnson, Andrew D., Sanghera, Dharambir K., Melander, Olle, Strbian, Daniel, Fernandez-Cadenas, Israel, Rolfs, Arndt, Hata, Jun, Woo, Daniel, Pare, Guillaume, Hopewell, Jemma C., Saleheen, Danish, Stefansson, Kari, Worrall, Bradford B., Seshadri, Sudha, Markus, Hugh S., Debette, Stephanie, Dichgans, Martin

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mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β 1 -induced collagen biosynthesis von Selvarajah, Brintha, Azuelos, Ilan, Platé, Manuela, Guillotin, Delphine, Forty, Ellen J, Contento, Greg, Woodcock, Hannah V, Redding, Matthew, Taylor, Adam, Brunori, Gino, Durrenberger, Pascal F, Ronzoni, Riccardo, Blanchard, Andy D, Mercer, Paul F, Anastasiou, Dimitrios, Chambers, Rachel C

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A catalog of genetic loci associated with kidney function from analyses of a million individuals von Wuttke, Matthias, Tin, Adrienne, Chai, Jin-Fang, Tayo, Bamidele O., Fuchsberger, Christian, Xu, Yizhe, Yu, Zhi, Akiyama, Masato, Ahluwalia, Tarunveer S., Amin, Najaf, Boissel, Mathilde, Boutin, Thibaud S., Brenner, Hermann, Campbell, Archie, Cusi, Daniele, Daw, E. Warwick, de Borst, Martin H., Delgado, Graciela, Dorajoo, Rajkumar, Elliott, Paul, Endlich, Karlhans, Franco, Oscar H., Franke, Andre, Freitag-Wolf, Sandra, Froguel, Philippe, Gaziano, J. Michael, Gieger, Christian, Gögele, Martin, Gudbjartsson, Daniel F., Gudnason, Vilmundur, Haller, Toomas, Hicks, Andrew A., Hofer, Edith, Ingelsson, Erik, Jaddoe, Vincent W. V., Jakobsdottir, Johanna, Jonas, Jost B., Joshi, Peter K., Jung, Bettina, Kerr, Shona M., Kooner, Jaspal S., Körner, Antje, Kovacs, Peter, Krajcoviechova, Alena, Krämer, Bernhard K., Kuokkanen, Mikko, Langefeld, Carl D., Lieb, Wolfgang, Lim, Su-Chi, Loos, Ruth J. F., Lucae, Susanne, Martins, Jade, Matsuda, Koichi, Milaneschi, Yuri, Miliku, Kozeta, Montgomery, Grant W., Nolte, Ilja M., Noordam, Raymond, Orho-Melander, Marju, Palsson, Runolfur, Perola, Markus, Pirastu, Mario, Podgornaia, Anna I., Ponte, Belen, Pramstaller, Peter P., Prins, Bram P., Raffield, Laura M., Ridker, Paul M., Roberts, David J., Rudan, Igor, Saba, Yasaman, Saum, Kai-Uwe, Schöttker, Ben, Smith, Albert V., Smith, Blair H., Taylor, Kent D., Thomsen, Hauke, Toniolo, Daniela, Tönjes, Anke, van Dam, Rob M., Verweij, Niek, Völker, Uwe, Wallentin, Lars, Waterworth, Dawn M., White, Harvey, Wild, Sarah H., Wilson, James F., Yerges-Armstrong, Laura M., Bochud, Murielle, Wilson, James G., Parsa, Afshin, Chasman, Daniel I., Pendergrass, Sarah A., Sim, Xueling, Böger, Carsten A., Okada, Yukinori, Hung, Adriana M., Scholz, Markus, Köttgen, Anna, Pattaro, Cristian

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Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis von Guillotin, Delphine, Taylor, Adam R, Platé, Manuela, Mercer, Paul F, Edwards, Lindsay M, Haggart, Ross, Miele, Gino, McAnulty, Robin J, Maher, Toby M, Hynds, Robert E, Jamal-Hanjani, Mariam, Marshall, Richard P, Fisher, Andrew J, Blanchard, Andy D, Chambers, Rachel C

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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease von Zanoni, Paolo, Khetarpal, Sumeet A., Larach, Daniel B., Hancock-Cerutti, William F., Millar, John S., Cuchel, Marina, DerOhannessian, Stephanie, Kontush, Anatol, Surendran, Praveen, Saleheen, Danish, Trompet, Stella, Jukema, J. Wouter, De Craen, Anton, Deloukas, Panos, Sattar, Naveed, Ford, Ian, Packard, Chris, Majumder, Abdullah al Shafi, Alam, Dewan S., Di Angelantonio, Emanuele, Abecasis, Goncalo, Chowdhury, Rajiv, Erdmann, Jeanette, Nordestgaard, Børge G., Nielsen, Sune F., Tybjærg-Hansen, Anne, Schmidt, Ruth Frikke, Kuulasmaa, Kari, Liu, Dajiang J., Perola, Markus, Blankenberg, Stefan, Salomaa, Veikko, Männistö, Satu, Amouyel, Philippe, Arveiler, Dominique, Ferrieres, Jean, Müller-Nurasyid, Martina, Ferrario, Marco, Kee, Frank, Willer, Cristen J., Samani, Nilesh, Schunkert, Heribert, Butterworth, Adam S., Howson, Joanna M. M., Peloso, Gina M., Stitziel, Nathan O., Danesh, John, Kathiresan, Sekar, Rader, Daniel J.

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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci von Liu, Mengzhen, Jackson, Victoria E., Melbourne, Carl A., Young, Robin, Batini, Chiara, Afaq, Saima, Agrawal, Arpana, Antoniou, Antonis C., Baumbach, Clemens, Boehnke, Michael, Brazel, David M, Chen, Chu, Corley, Janie, Chou, Yi-Ling, David, Sean P., de Boer, Rudolf A., Dennis, Joe G., Easton, Douglas F., Eaton, Charles, Goate, Alison, Grabe, Hans J., Haessler, Jeff, Hallmans, Göran, Harris, Sarah E., Hattersley, Andrew, Heath, Andrew, Kapoor, Manav, Karpe, Fredrik, Kooner, Jaspal S., Kooperberg, Charles, Laakso, Markku, Langenberg, Claudia, Luan, Jian’an, Madden, Pamela A. F., Mangino, Massimo, Marouli, Eirini, Marten, Jonathan, McGue, Matt, Moayyeri, Alireza, Moitry, Marie, Naheed, Aliya, Nauck, Matthias, Neville, Matthew J., Nielsen, Sune Fallgaard, Perola, Markus, Pharoah, Paul D. P., Rasheed, Asif, Renström, Frida, Rice, John, Rohde, Rebecca, Samuel, Maria, Scholte, Steven H, Scott, Robert A., Shao, Yaming, Smith, Jennifer A., Starr, John M., Stram, Danielle, Stringham, Heather M., Tachmazidou, Ioanna, Tardif, Jean-Claude, Thompson, Deborah J., Tindle, Hilary A., Tragante, Vinicius, Trompet, Stella, Turcot, Valerie, Tyrrell, Jessica, van der Leij, Andries R, van der Meer, Peter, Verweij, Niek, Warren, Helen R., Weiss, Stefan, Wetherill, Leah, Yaghootkar, Hanieh, Jiang, Yu, Chen, Fang, Zhan, Xiaowei, Zhang, Weihua, Zhao, Wei, Zhao, Wei, Zhou, Kaixin, Amouyel, Philippe, Blankenberg, Stefan, Caulfield, Mark J., Chowdhury, Rajiv, Cucca, Francesco, Deary, Ian J., Deloukas, Panos, Ferrario, Marco, Frossard, Philippe, Hall, Ian P., Jansson, Jan-Håkan, Kee, Frank, Munroe, Patricia B., Palmer, Colin N. A., Sattar, Naveed, Spector, Timothy, Zeggini, Eleftheria, Saleheen, Danish, Danesh, John, Tobin, Martin D.

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Association analyses based on false discovery rate implicate new loci for coronary artery disease von Nelson, Christopher P, Goel, Anuj, Butterworth, Adam S, Kanoni, Stavroula, Webb, Tom R, Marouli, Eirini, Zeng, Lingyao, Ntalla, Ioanna, Lai, Florence Y, Hopewell, Jemma C, Giannakopoulou, Olga, Jiang, Tao, Hamby, Stephen E, Di Angelantonio, Emanuele, Assimes, Themistocles L, Bottinger, Erwin P, Chambers, John C, Clarke, Robert, Palmer, Colin N A, Cubbon, Richard M, Ellinor, Patrick, Ermel, Raili, Evangelou, Evangelos, Franks, Paul W, Grace, Christopher, Gu, Dongfeng, Hingorani, Aroon D, Howson, Joanna M M, Ingelsson, Erik, Kastrati, Adnan, Kessler, Thorsten, Kyriakou, Theodosios, Lehtimäki, Terho, Lu, Xiangfeng, Lu, Yingchang, März, Winfried, McPherson, Ruth, Metspalu, Andres, Pujades-Rodriguez, Mar, Ruusalepp, Arno, Schadt, Eric E, Schmidt, Amand F, Sweeting, Michael J, Zalloua, Pierre A, AlGhalayini, Kamal, Keavney, Bernard D, Kooner, Jaspal S, Loos, Ruth J F, Patel, Riyaz S, Rutter, Martin K, Tomaszewski, Maciej, Tzoulaki, Ioanna, Zeggini, Eleftheria, Erdmann, Jeanette, Dedoussis, George, Björkegren, Johan L M, Schunkert, Heribert, Farrall, Martin, Danesh, John, Samani, Nilesh J, Watkins, Hugh, Deloukas, Panos

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