Discovery of microbial natural products by activation of silent biosynthetic gene clusters von Rutledge, Peter J., Challis, Gregory L.

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Mining microbial genomes for new natural products and biosynthetic pathways von Challis, Gregory L

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Genome Mining for Novel Natural Product Discovery von Challis, Gregory L

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Mechanism and Catalytic Diversity of Rieske Non-Heme Iron-Dependent Oxygenases von Barry, Sarah M, Challis, Gregory L

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Strategies for the Discovery of New Natural Products by Genome Mining von Zerikly, Malek, Challis, Gregory L

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Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens von Laureti, Luisa, Song, Lijiang, Huang, Sheng, Corre, Christophe, Leblond, Pierre, Challis, Gregory L, Aigle, Bertrand

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Catalytic Mechanism of Aromatic Nitration by Cytochrome P450 TxtE: Involvement of a Ferric-Peroxynitrite Intermediate von Louka, Savvas, Barry, Sarah M, Heyes, Derren J, Mubarak, M. Qadri E, Ali, Hafiz Saqib, Alkhalaf, Lona M, Munro, Andrew W, Scrutton, Nigel S, Challis, Gregory L, de Visser, Sam P

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Widely Distributed Bacterial Pathway for Siderophore Biosynthesis Independent of Nonribosomal Peptide Synthetases von Challis, Gregory L

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Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity von Izoré, Thierry, Candace Ho, Y. T., Kaczmarski, Joe A., Gavriilidou, Athina, Chow, Ka Ho, Steer, David L., Goode, Robert J. A., Schittenhelm, Ralf B., Tailhades, Julien, Tosin, Manuela, Challis, Gregory L., Krenske, Elizabeth H., Ziemert, Nadine, Jackson, Colin J., Cryle, Max J.

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New natural product biosynthetic chemistry discovered by genome mining von Corre, Christophe, Challis, Gregory L

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Synergy and Contingency as Driving Forces for the Evolution of Multiple Secondary Metabolite Production by Streptomyces Species von Challis, Gregory L., Hopwood, David A.

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Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis von Huang, Chuan, Zabala, Daniel, de Los Santos, Emmanuel L C, Song, Lijiang, Corre, Christophe, Alkhalaf, Lona M, Challis, Gregory L

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A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis von Masschelein, Joleen, Sydor, Paulina K., Hobson, Christian, Howe, Rhiannon, Jones, Cerith, Roberts, Douglas M., Ling Yap, Zhong, Parkhill, Julian, Mahenthiralingam, Eshwar, Challis, Gregory L.

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Genomics‐Driven Discovery of a Novel Glutarimide Antibiotic from Burkholderia gladioli Reveals an Unusual Polyketide Synthase Chain Release Mechanism von Nakou, Ioanna T., Jenner, Matthew, Dashti, Yousef, Romero‐Canelón, Isolda, Masschelein, Joleen, Mahenthiralingam, Eshwar, Challis, Gregory L.

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Stereochemistry and Mechanism of Undecylprodigiosin Oxidative Carbocyclization to Streptorubin B by the Rieske Oxygenase RedG von Withall, David M, Haynes, Stuart W, Challis, Gregory L

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Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC von Alkhalaf, Lona M, Barry, Sarah M, Rea, Dean, Gallo, Angelo, Griffiths, Daniel, Lewandowski, Józef R, Fulop, Vilmos, Challis, Gregory L

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Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis von Barry, Sarah M, Kers, Johan A, Johnson, Evan G, Song, Lijiang, Aston, Philip R, Patel, Bhumit, Krasnoff, Stuart B, Crane, Brian R, Gibson, Donna M, Loria, Rosemary, Challis, Gregory L

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Antimalarial Activity of Natural and Synthetic Prodiginines von Papireddy, Kancharla, Smilkstein, Martin, Kelly, Jane Xu, Shweta, Salem, Shaimaa M, Alhamadsheh, Mamoun, Haynes, Stuart W, Challis, Gregory L, Reynolds, Kevin A

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Docking domain-mediated subunit interactions in natural product megasynth(et)ases von Smith, Helen G, Beech, Matthew J, Lewandowski, Józef R, Challis, Gregory L, Jenner, Matthew

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The long-overlooked enzymology of a nonribosomal peptide synthetase-independent pathway for virulence-conferring siderophore biosynthesis von Oves-Costales, Daniel, Kadi, Nadia, Challis, Gregory L

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