Synthesis, in vitro binding profile, and autoradiographic analysis of [3H]-cis-3-[(2-methoxybenzyl)amino]-2-phenylpiperidine, a highly potent and selective nonpeptide substance P r... von Rosen, Terry, Seeger, Thomas F, McLean, Stafford, Desai, Manoj C, Guarino, Karen J, Bryce, Dianne, Pratt, Kara, Heym, James, Chalabi, Philip M

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European Academy of Neurology (EAN) guideline on the management of amyotrophic lateral sclerosis in collaboration with European Reference Network for Neuromuscular Diseases (ERN EU... von Van Damme, Philip, Al‐Chalabi, Ammar, Andersen, Peter M., Chiò, Adriano, Couratier, Philippe, De Carvalho, Mamede, Hardiman, Orla, Kuźma‐Kozakiewicz, Magdalena, Ludolph, Albert, McDermott, Christopher J., Mora, Jesus S., Petri, Susanne, Probyn, Katrin, Reviers, Evy, Salachas, François, Silani, Vincenzo, Tysnes, Ole‐Bjørn, Berg, Leonard H., Villanueva, Gemma, Weber, Markus

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EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans von Van Hoecke, Annelies, Schoonaert, Lies, Lemmens, Robin, Timmers, Mieke, Staats, Kim A, Laird, Angela S, Peeters, Elke, Philips, Thomas, Goris, An, Dubois, Bénédicte, Andersen, Peter M, Al-Chalabi, Ammar, Thijs, Vincent, Turnley, Ann M, van Vught, Paul W, Veldink, Jan H, Hardiman, Orla, Van Den Bosch, Ludo, Gonzalez-Perez, Paloma, Van Damme, Philip, Brown, Robert H, van den Berg, Leonard H, Robberecht, Wim

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Elongator subunit 3 (ELP3) modifies ALS through tRNA modification von Bento-Abreu, Andre, Jager, Gunilla, Swinnen, Bart, Rué, Laura, Hendrickx, Stijn, Jones, Ashley, Staats, Kim A, Taes, Ines, Eykens, Caroline, Nonneman, Annelies, Nuyts, Rik, Timmers, Mieke, Silva, Lara, Chariot, Alain, Nguyen, Laurent, Ravits, John, Lemmens, Robin, Cabooter, Deirdre, Van Den Bosch, Ludo, Van Damme, Philip, Al-Chalabi, Ammar, Bystrom, Anders, Robberecht, Wim

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PRECISION ALS-an integrated pan European patient data platform for ALS von McFarlane, R, Galvin, M, Heverin, M, Mac Domhnaill, E, Murray, D, Meldrum, D, Bede, P, Bolger, A, Hederman, L, Impey, S, Stephens, G, O'Meara, C, Wade, V, Al Chalabi, A, Chio, A, Corcia, P, van Damme, P, Ingre, C, McDermott, C, Povedanos, M, Van den Berg, L, Hardiman, O

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Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial von Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen

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UNC13A in amyotrophic lateral sclerosis: from genetic association to therapeutic target von Willemse, SW, Harley, P, van Eijk, RPA, Demaegd, KC, Zelina, P, Pasterkamp, RJ, van Damme, P, Ingre, C, van Rheenen, W, Veldink, JH, Kiernan, MC, Al-Chalabi, A, van den Berg, LH, Fratta, P, van Es, MA

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The Effect of SMN Gene Dosage on ALS Risk and Disease Severity von Moisse, Matthieu, Zwamborn, Ramona A. J., Vugt, Joke, Spek, Rick, Rheenen, Wouter, Kenna, Brendan, Van Eijk, Kristel, Kenna, Kevin, Corcia, Philippe, Couratier, Philippe, Vourc'h, Patrick, Hardiman, Orla, McLaughin, Russell, Gotkine, Marc, Drory, Vivian, Ticozzi, Nicola, Silani, Vincenzo, Carvalho, Mamede, Mora Pardina, Jesús S., Povedano, Monica, Andersen, Peter M., Weber, Markus, Başak, Nazli A., Chen, Xiao, Eberle, Michael A., Al‐Chalabi, Ammar, Shaw, Chris, Shaw, Pamela J., Morrison, Karen E., Landers, John E., Glass, Jonathan D., Robberecht, Wim, Es, Michael, Berg, Leonard, Veldink, Jan, Van Damme, Philip

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Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study von Prins, Bram P, Abbasi, Ali, Wong, Anson, Vaez, Ahmad, Nolte, Ilja, Franceschini, Nora, Stuart, Philip E, Guterriez Achury, Javier, Mistry, Vanisha, Bradfield, Jonathan P, Valdes, Ana M, Bras, Jose, Shatunov, Aleksey, Lu, Chen, Han, Buhm, Raychaudhuri, Soumya, Bevan, Steve, Mayes, Maureen D, Tsoi, Lam C, Evangelou, Evangelos, Nair, Rajan P, Grant, Struan F A, Polychronakos, Constantin, Radstake, Timothy R D, van Heel, David A, Dunstan, Melanie L, Wood, Nicholas W, Al-Chalabi, Ammar, Dehghan, Abbas, Hakonarson, Hakon, Markus, Hugh S, Elder, James T, Knight, Jo, Arking, Dan E, Spector, Timothy D, Koeleman, Bobby P C, van Duijn, Cornelia M, Martin, Javier, Morris, Andrew P, Weersma, Rinse K, Wijmenga, Cisca, Munroe, Patricia B, Perry, John R B, Pouget, Jennie G, Jamshidi, Yalda, Snieder, Harold, Alizadeh, Behrooz Z

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The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis von Salmon, Kristiana, Kiernan, Matthew C, Kim, Seung H, Andersen, Peter M, Chio, Adriano, van den Berg, Leonard H, Van Damme, Philip, Al-Chalabi, Ammar, Lillo, Patricia, Andrews, Jinsy A, Genge, Angela

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Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis von Wouter Van Rheenen, Pulit, Sara L, Dekker, Annelot M, Ahmad Al Khleifat, Brands, William J, Iacoangeli, Alfredo, Kenna, Kevin P, Kavak, Ersen, Kooyman, Maarten, McLaughlin, Russell L, Middelkoop, Bas, Moisse, Matthieu, Schellevis, Raymond D, Shatunov, Aleksey, Sproviero, William, Tazelaar, Gijs H P, Rick A A Van der Spek, Perry T C Van Doormaal, Van Eijk, Kristel R, Joke Van Vugt, Basak, A Nazli, Blair, Ian P, Glass, Jonathan D, Hardiman, Orla, Hide, Winston, Landers, John E, Mora, Jesus S, Morrison, Karen E, Newhouse, Stephen, Robberecht, Wim, Shaw, Christopher E, Shaw, Pamela J, Philip Van Damme, Van Es, Michael A, Wray, Naomi R, Al-Chalabi, Ammar, Leonard H Van den Berg, Veldink, Jan H

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Lithium carbonate in amyotrophic lateral sclerosis patients homozygous for the C-allele at SNP rs12608932 in UNC13A: protocol for a confirmatory, randomized, group-sequential, even... von Willemse, Sean W, Roes, Kit C B, Van Damme, Philip, Hardiman, Orla, Ingre, Caroline, Povedano, Monica, Wray, Naomi R, Gijzen, Marleen, de Pagter, Mirjam S, Demaegd, Koen C, Janse, Annemarie F C, Vink, Roel G, Sleutjes, Boudewijn T H M, Chiò, Adriano, Corcia, Philippe, Reviers, Evy, Al-Chalabi, Ammar, Kiernan, Matthew C, van den Berg, Leonard H, van Es, Michael A, van Eijk, Ruben P A

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CHCHD10 variants in amyotrophic lateral sclerosis: Where is the evidence? von Tazelaar, Gijs H.P., van Rheenen, Wouter, Pulit, Sara L., van der Spek, Rick A.A., Dekker, Annelot M., Moisse, Matthieu, McLaughlin, Russell L., Sproviero, William, Kenna, Kevin P., Kooyman, Maarten, van Doormaal, Perry T.C., van Eijk, Kristel E., Middelkoop, Bas M., Schellevis, Raymond D., Brands, William J., Al‐Chalabi, Ammar, Morrison, Karen E., Shaw, Pamela J., Shaw, Christopher E., Newhouse, Stephen E., van Es, Michael A., Basak, A. Nazli, Akçimen, Fulya, Kocoglu, Cemile, Tunca, Ceren, Povedano, Monica, Mora, Jesus S., Glass, Jonathan D., Van Damme, Philip, Robberecht, Wim, HardimanMD, Orla, Landers, John E., van den Berg, Leonard H., Veldink, Jan H.

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Mutations in the tail and rod domains of the neurofilament heavy‐chain gene increase the risk of ALS von Marriott, Heather, Spargo, Thomas P., Al Khleifat, Ahmad, Andersen, Peter M, Başak, Nazli A., Cooper‐Knock, Johnathan, Corcia, Philippe, Couratier, Philippe, Carvalho, Mamede, Drory, Vivian, Gotkine, Marc, Landers, John E., McLaughlin, Russell, Pardina, Jesús S. Mora, Morrison, Karen E., Pinto, Susana, Shaw, Christopher E., Shaw, Pamela J., Silani, Vincenzo, Ticozzi, Nicola, Damme, Philip, Berg, Leonard H., Vourc'h, Patrick, Weber, Markus, Veldink, Jan H., Al Khleifat, Ahmad, Al‐Chalabi, Ammar, Andersen, Peter M, Başak, Nazli A., Cooper‐Knock, Johnathan, Corcia, Philippe, Couratier, Philippe, Carvalho, Mamede, Drory, Vivian, Glass, Jonathan D., Gotkine, Marc, Hardiman, Orla, Iacoangeli, Alfredo, Landers, John E., McLaughlin, Russell, Pardina, Jesús S. Mora, Morrison, Karen E., Pinto, Susana, Povedano, Monica, Shaw, Christopher E., Shaw, Pamela J., Silani, Vincenzo, Ticozzi, Nicola, Damme, Philip, Berg, Leonard H., Vourc'h, Patrick, Weber, Markus, Veldink, Jan H., Dobson, Richard J., Schwab, Patrick, Al‐Chalabi, Ammar, Iacoangeli, Alfredo

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The impact of age on genetic testing decisions in amyotrophic lateral sclerosis von Mehta, Puja R, Iacoangeli, Alfredo, Opie-Martin, Sarah, van Vugt, Joke J F A, Al Khleifat, Ahmad, Bredin, Andrea, Ossher, Lynn, Andersen, Peter M, Hardiman, Orla, Mehta, Arpan R, Fratta, Pietro, Talbot, Kevin, Al-Chalabi, Ammar

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Genetic variability in sporadic amyotrophic lateral sclerosis von Van Daele, Sien Hilde, Moisse, Matthieu, van Vugt, Joke J F A, Zwamborn, Ramona A J, van der Spek, Rick, van Rheenen, Wouter, Van Eijk, Kristel, Kenna, Kevin, Corcia, Philippe, Vourc'h, Patrick, Couratier, Philippe, Hardiman, Orla, McLaughin, Russell, Gotkine, Marc, Drory, Vivian, Ticozzi, Nicola, Silani, Vincenzo, Ratti, Antonia, de Carvalho, Mamede, Mora Pardina, Jesús S, Povedano, Monica, Andersen, Peter M, Weber, Markus, Başak, Nazli A, Shaw, Chris, Shaw, Pamela J, Morrison, Karen E, Landers, John E, Glass, Jonathan D, van Es, Michael A, van den Berg, Leonard H, Al-Chalabi, Ammar, Veldink, Jan, Van Damme, Philip

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TRICALS: creating a highway toward a cure von van Eijk, RPA, Kliest, T, McDermott, CJ, Roes, KCB, Van Damme, P, Chio, A, Weber, M, Ingre, C, Corcia, P, Povedano, M, Reviers, E, van Es, MA, Al-Chalabi, A, Hardiman, O, van den Berg, LH

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Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3′UTR protect against ALS von Eitan, Chen, Siany, Aviad, Barkan, Elad, Olender, Tsviya, van Eijk, Kristel R., Moisse, Matthieu, Farhan, Sali M. K., Danino, Yehuda M., Yanowski, Eran, Marmor-Kollet, Hagai, Rivkin, Natalia, Yacovzada, Nancy Sarah, Hung, Shu-Ting, Cooper-Knock, Johnathan, Yu, Chien-Hsiung, Louis, Cynthia, Masters, Seth L., Kenna, Kevin P., van der Spek, Rick A. A., Sproviero, William, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Jones, Ashley R., Elbaz-Alon, Yael, Cohen, Yahel, Chapnik, Elik, Rothschild, Daphna, Weissbrod, Omer, Beck, Gilad, Ainbinder, Elena, Ben-Dor, Shifra, Werneburg, Sebastian, Schafer, Dorothy P., Brown, Robert H., Shaw, Pamela J., Van Damme, Philip, van den Berg, Leonard H., Phatnani, Hemali, Segal, Eran, Ichida, Justin K., Al-Chalabi, Ammar, Veldink, Jan H., Hornstein, Eran

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ATXN2 Trinucleotide Repeat Length Correlates with Risk of ALS von Sproviero, William, Shatunov, Aleksey, Stahl, Daniel, Shoai, Maryam, van Rheenen, Wouter, Jones, Ashley R, Al-Sarraj, Safa, Andersen, Peter M, Bonini, Nancy M, Conforti, Francesca L, Van Damme, Philip, Daoud, Hussein, Del Mar Amador, Maria, Fogh, Isabella, Forzan, Monica, Gaastra, Ben, Gellera, Cinzia, Gitler, Aaron D, Hardy, John, Fratta, Pietro, La Bella, Vincenzo, Le Ber, Isabelle, Van Langenhove, Tim, Lattante, Serena, Lee, Yi-Chung, Malaspina, Andrea, Meininger, Vincent, Millecamps, Stèphanie, Orrell, Richard, Rademakers, Rosa, Robberecht, Wim, Rouleau, Guy, Ross, Owen A, Salachas, Francois, Sidle, Katie, Smith, Bradley N, Soong, Bing-Wen, Sorarù, Gianni, Stevanin, Giovanni, Kabashi, Edor, Troakes, Claire, van Broeckhoven, Christine, Veldink, Jan H, van den Berg, Leonard H, Shaw, Christopher E, Powell, John F, Al-Chalabi, Ammar

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The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis von Salmon, Kristiana, Kiernan, Matthew C, Kim, Seung H, Andersen, Peter M, Chio, Adriano, van den Berg, Leonard H, Van Damme, Philip, Al-Chalabi, Ammar, Lillo, Patricia, Andrews, Jinsy A, Genge, Angela

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