The APP intracellular domain promotes LRRK2 expression to enable feed-forward neurodegenerative mechanisms in Parkinson’s disease von Zhang, Zhi-Wei, Tu, Haitao, Jiang, Mei, Vanan, Sarivin, Chia, Sook Yoong, Jang, Se-Eun, Saw, Wuan-Ting, Ong, Zhi-Wei, Ma, Dong-Rui, Zhou, Zhi-Dong, Xu, Jie, Guo, Kai-Hua, Yu, Wei-Ping, Ling, Shuo-Chien, Margolin, Richard A., Chain, Daniel G., Zeng, Li, Tan, Eng-King

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AlphaFold 2 predicts opening of the tau hairpin conformation by Mapt mutations and the extent of opening reflects their location von Chain, Daniel G, Margolin, Richard A

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The AI‐based AlphaFold 2 algorithm predicts an open structure for tauC3 von Chain, Daniel G, Margolin, Richard A

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Development of indole-3-propionic acid (OXIGON) for Alzheimer's disease von Bendheim, Paul E, Poeggeler, Burkhard, Neria, Eyal, Ziv, Vivi, Pappolla, Miguel A, Chain, Daniel G

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Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia von Chain, Daniel G, Casadio, Andrea, Schacher, Samuel, Hegde, Ashok N, Valbrun, Mireille, Yamamoto, Naoki, Goldberg, Alfred L, Bartsch, Dusan, Kandel, Eric R, Schwartz, James H

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AlphaFold 2 predicts a markedly different MTBR conformation for 3‐repeat and 4‐repeat tau isoforms von Chain, Daniel G, Margolin, Richard A, Pollack, Scott, Goncalves, Maria Beatriz de Castro V.

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Basic Science and Pathogenesis von Chain, Daniel G, Margolin, Richard A, Pollack, Scott, Goncalves, Maria Beatriz de Castro V

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Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia von Hegde, Ashok N., Inokuchi, Kaoru, Pei, Wanzheng, Casadio, Andrea, Ghirardi, Mirella, Chain, Daniel G., Martin, Kelsey C., Kandel, Eric R., Schwartz, James H.

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Ubiquitin-mediated proteolysis in learning and memory von Chain, D G, Schwartz, J H, Hegde, A N

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Activation and Degradation of the Transcription Factor C/EBP During Long‐Term Facilitation in Aplysia von Yamamoto, Naoki, Hegde, Ashok N., Chain, Daniel G., Schwartz, James H.

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P3‐012: Advancing Therapeutics for Neuroinflammation in Alzheimer's Disease: Clinical Development Considerations von Margolin, Richard A., Schneider, Lon S., Cutter, Gary R., Breitner, John C.S., Doody, Rachelle S., Landreth, Gary, Chain, Daniel

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Potent Neuroprotective Properties against the Alzheimer β-Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid von Chyan, Yau-Jan, Poeggeler, Burkhard, Omar, Rawhi A., Chain, Daniel G., Frangione, Blas, Ghiso, Jorge, Pappolla, Miguel A.

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FUSION CONSTRUCTS AND USES THEREOF von CHAIN, Daniel

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O4‐11‐01: RELATIONSHIP BETWEEN CEREBROSPINAL FLUID (CSF) BIOMARKERS AND COGNITIVE PERFORMANCE OF PATIENTS WITH MILD COGNITIVE IMPAIRMENT (MCI) AFTER LONG‐TERM TREATMENT WITH CHF507... von Imbimbo, Bruno Pietro, Fernandez, Mercedes, Giardino, Luciana, Calzà, Laura, Chain, Daniel, Margolin, Richard

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RELATIONSHIP BETWEEN CEREBROSPINAL FLUID (CSF) BIOMARKERS AND COGNITIVE PERFORMANCE OF PATIENTS WITH MILD COGNITIVE IMPAIRMENT (MCI) AFTER LONG-TERM TREATMENT WITH CHF5074 von Imbimbo, Bruno Pietro, Fernandez, Mercedes, Giardino, Luciana, Calzà, Laura, Chain, Daniel, Margolin, Richard

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Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease von Matsubara, Etsuro, Bryant‐Thomas, Tara, Pacheco Quinto, Javier, Henry, Tracey L., Poeggeler, Burkhard, Herbert, Donald, Cruz‐Sanchez, Felix, Chyan, Yau‐Jan, Smith, Mark A., Perry, George, Shoji, Mikio, Abe, Koji, Leone, Anna, Grundke‐Ikbal, Inge, Wilson, Glen L., Ghiso, Jorge, Williams, Christina, Refolo, Lorenzo M., Pappolla, Miguel A.

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FUSION CONSTRUCTS AND USES THEREOF von CHAIN, Daniel

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ADVANCING THERAPEUTICS FOR NEUROINFLAMMATION IN ALZHEIMER'S DISEASE: CLINICAL DEVELOPMENT CONSIDERATIONS von Margolin, Richard A, Schneider, Lon S, Cutter, Gary R, Breitner, John C.S, Doody, Rachelle S, Landreth, Gary, Chain, Daniel

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Distrito 9. Viviendas Mentoring von Fernández Chain, Daniel

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Plasmin cleavage of vitronectin Identification of the site and consequent attenuation in binding plasminogen activator inhibitor-1 von Chain, Daniel, Kreizman, Tamar, Shapira, Hadar, Shaltiel, Shmuel

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