Abstract 1738: XMT-2056, a well-tolerated, Immunosynthen-based STING-agonist antibody-drug conjugate which induces anti-tumor immune activity von Duvall, Jeremy R., Bukhalid, Raghida A., Cetinbas, Naniye M., Catcott, Kalli C., Slocum, Kelly, Avocetien, Kenneth, Bentley, Keith W., Bradley, Stephen, Clardy, Susan, Collins, Scott D., Ditty, Elizabeth, Eitas, Timothy, Jones, Brian D., Kelleher, Eugene W., Lee, Winnie, Monnell, Travis, Mosher, Rebecca, Protopopova, Marina, Qin, LiuLiang, Shaw, Pamela, Ter-Ovanesyan, Elena, Thomas, Joshua D., Wongthida, Phonphimon, Xu, Ling, Yang, Liping, Zurita, Jeffrey, Toader, Dorin, Damelin, Marc, Lowinger, Timothy B.

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In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis von Roper, Jatin, Tammela, Tuomas, Cetinbas, Naniye Malli, Akkad, Adam, Roghanian, Ali, Rickelt, Steffen, Almeqdadi, Mohammad, Wu, Katherine, Oberli, Matthias A, Sánchez-Rivera, Francisco J, Park, Yoona K, Liang, Xu, Eng, George, Taylor, Martin S, Azimi, Roxana, Kedrin, Dmitriy, Neupane, Rachit, Beyaz, Semir, Sicinska, Ewa T, Suarez, Yvelisse, Yoo, James, Chen, Lillian, Zukerberg, Lawrence, Katajisto, Pekka, Deshpande, Vikram, Bass, Adam J, Tsichlis, Philip N, Lees, Jacqueline, Langer, Robert, Hynes, Richard O, Chen, Jianzhu, Bhutkar, Arjun, Jacks, Tyler, Yilmaz, Ömer H

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HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response von Rotblat, Barak, Southwell, Amber L., Ehrnhoefer, Dagmar E., Skotte, Niels H., Metzler, Martina, Franciosi, Sonia, Leprivier, Gabriel, Somasekharan, Syam Prakash, Barokas, Adi, Yu Deng, Tang, Tiffany, Mathers, Joan, Cetinbas, Naniye, Daugaard, Mads, Kwok, Brian, Li, Liheng, Carnie, Christopher J., Fink, Dieter, Nitsch, Roberto, Galpin, Jason D., Ahern, Christopher A., Melino, Gerry, Penninger, Josef M., Hayden, Michael R., Sorensen, Poul H.

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