Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy von Sierra, J Rafael, Cepero, Virna, Giordano, Silvia

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MET and KRAS Gene Amplification Mediates Acquired Resistance to MET Tyrosine Kinase Inhibitors von CEPERO, Virna, SIERRA, J. Rafael, CORSO, Simona, GHISO, Elena, CASORZO, Laura, PERERA, Tim, COMOGLIO, Paolo Maria, GIORDANO, Silvia

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Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages von Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia

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Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition von Corso, Simona, Ghiso, Elena, Cepero, Virna, Sierra, J Rafael, Migliore, Cristina, Bertotti, Andrea, Trusolino, Livio, Comoglio, Paolo M, Giordano, Silvia

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(A and B) Immunofluorescence analysis of tumors grown in WT or Sema4D KO animals von Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia

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(A) Matrigel plugs containing either WT or KO TAMs were subcutaneously implanted in KO mice von Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia

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(A) TSA breast cancer cells were subcutaneously injected in WT and Sema4D KO mice von Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia

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(A) CD45 cells express Sema4D von Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia

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(A and B) Evaluation of tumor vascularization von Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia

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