An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme von Ceccarelli, Derek F., Tang, Xiaojing, Pelletier, Benoit, Orlicky, Stephen, Xie, Weilin, Plantevin, Veronique, Neculai, Dante, Chou, Yang-Chieh, Ogunjimi, Abiodun, Al-Hakim, Abdallah, Varelas, Xaralabos, Koszela, Joanna, Wasney, Gregory A., Vedadi, Masoud, Dhe-Paganon, Sirano, Cox, Sarah, Xu, Shuichan, Lopez-Girona, Antonia, Mercurio, Frank, Wrana, Jeff, Durocher, Daniel, Meloche, Sylvain, Webb, David R., Tyers, Mike, Sicheri, Frank

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Cleavage Furrow Organization Requires PIP2-Mediated Recruitment of Anillin von Liu, Jinghe, Fairn, Gregory D., Ceccarelli, Derek F., Sicheri, Frank, Wilde, Andrew

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The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis von Rivkin, Elena, Almeida, Stephanie M., Ceccarelli, Derek F., Juang, Yu-Chi, MacLean, Teresa A., Srikumar, Tharan, Huang, Hao, Dunham, Wade H., Fukumura, Ryutaro, Xie, Gang, Gondo, Yoichi, Raught, Brian, Gingras, Anne-Claude, Sicheri, Frank, Cordes, Sabine P.

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Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity von Huang, Hao, Zeqiraj, Elton, Dong, Beihua, Jha, Babal Kant, Duffy, Nicole M., Orlicky, Stephen, Thevakumaran, Neroshan, Talukdar, Manisha, Pillon, Monica C., Ceccarelli, Derek F., Wan, Leo C.K., Juang, Yu-Chi, Mao, Daniel Y.L., Gaughan, Christina, Brinton, Margo A., Perelygin, Andrey A., Kourinov, Igor, Guarné, Alba, Silverman, Robert H., Sicheri, Frank

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A substrate binding model for the KEOPS tRNA modifying complex von Beenstock, Jonah, Ona, Samara Mishelle, Porat, Jennifer, Orlicky, Stephen, Wan, Leo C. K., Ceccarelli, Derek F., Maisonneuve, Pierre, Szilard, Rachel K., Yin, Zhe, Setiaputra, Dheva, Mao, Daniel Y. L., Khan, Morgan, Raval, Shaunak, Schriemer, David C., Bayfield, Mark A., Durocher, Daniel, Sicheri, Frank

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FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation von Barbulescu, Philip, Chana, Chetan K., Wong, Matthew K., Ben Makhlouf, Ines, Bruce, Jeffrey P., Feng, Yuqing, Keszei, Alexander F. A., Wong, Cassandra, Mohamad-Ramshan, Rukshana, McGary, Laura C., Kashem, Mohammad A., Ceccarelli, Derek F., Orlicky, Stephen, Fang, Yifei, Kuang, Huihui, Mazhab-Jafari, Mohammad, Pezo, Rossanna C., Bhagwat, Ashok S., Pugh, Trevor J., Gingras, Anne-Claude, Sicheri, Frank, Martin, Alberto

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Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay von Koszela, Joanna, Pham, Nhan T, Evans, David, Mann, Stefan, Perez-Pi, Irene, Shave, Steven, Ceccarelli, Derek F J, Sicheri, Frank, Tyers, Mike, Auer, Manfred

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Higher-Order Assembly of BRCC36–KIAA0157 Is Required for DUB Activity and Biological Function von Zeqiraj, Elton, Tian, Lei, Piggott, Christopher A., Pillon, Monica C., Duffy, Nicole M., Ceccarelli, Derek F., Keszei, Alexander F.A., Lorenzen, Kristina, Kurinov, Igor, Orlicky, Stephen, Gish, Gerald D., Heck, Albert J.R., Guarné, Alba, Greenberg, Roger A., Sicheri, Frank

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Spatial and Temporal Regulation of Focal Adhesion Kinase Activity in Living Cells von Cai, Xinming, Lietha, Daniel, Ceccarelli, Derek F., Karginov, Andrei V., Rajfur, Zenon, Jacobson, Ken, Hahn, Klaus M., Eck, Michael J., Schaller, Michael D.

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OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function von Juang, Yu-Chi, Landry, Marie-Claude, Sanches, Mario, Vittal, Vinayak, Leung, Charles C.Y., Ceccarelli, Derek F., Mateo, Abigail-Rachele F., Pruneda, Jonathan N., Mao, Daniel Y.L., Szilard, Rachel K., Orlicky, Stephen, Munro, Meagan, Brzovic, Peter S., Klevit, Rachel E., Sicheri, Frank, Durocher, Daniel

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Dissecting BAR domain function in the yeast Amphiphysins Rvs161 and Rvs167 during endocytosis von Youn, Ji-Young, Friesen, Helena, Kishimoto, Takuma, Henne, William M, Kurat, Christoph F, Ye, Wei, Ceccarelli, Derek F, Sicheri, Frank, Kohlwein, Sepp D, McMahon, Harvey T, Andrews, Brenda J

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Atomic Structure of the KEOPS Complex: An Ancient Protein Kinase-Containing Molecular Machine von Mao, Daniel Y.L., Neculai, Dante, Downey, Michael, Orlicky, Stephen, Haffani, Yosr Z., Ceccarelli, Derek F., Ho, Jenny S.L., Szilard, Rachel K., Zhang, Wei, Ho, Cynthia S., Wan, Leo, Fares, Christophe, Rumpel, Sigrun, Kurinov, Igor, Arrowsmith, Cheryl H., Durocher, Daniel, Sicheri, Frank

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Bipartite binding of the N terminus of Skp2 to cyclin A von Kelso, Susan, Orlicky, Stephen, Beenstock, Jonah, Ceccarelli, Derek F., Kurinov, Igor, Gish, Gerald, Sicheri, Frank

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Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9 von Ceccarelli, Derek F.J., Blasutig, Ivan M., Goudreault, Marilyn, Li, Zhiqin, Ruston, Julie, Pawson, Tony, Sicheri, Frank

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Structural Basis for the Autoinhibition of Focal Adhesion Kinase von Lietha, Daniel, Cai, Xinming, Ceccarelli, Derek F.J., Li, Yiqun, Schaller, Michael D., Eck, Michael J.

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A Novel Confocal Scanning Protein–Protein Interaction Assay (PPI-CONA) Reveals Exceptional Selectivity and Specificity of CC0651, a Small Molecule Binding Enhancer of the Weak Inte... von Koszela, Joanna, Pham, Nhan T., Shave, Steven, St-Cyr, Daniel, Ceccarelli, Derek F., Orlicky, Steven, Marinier, Anne, Sicheri, Frank, Tyers, Mike, Auer, Manfred

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Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes von Garg, Pankaj, Ceccarelli, Derek F., Keszei, Alexander F.A., Kurinov, Igor, Sicheri, Frank, Sidhu, Sachdev S.

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Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4 von Chana, Chetan K., Maisonneuve, Pierre, Posternak, Ganna, Grinberg, Nicolas G.A., Poirson, Juline, Ona, Samara M., Ceccarelli, Derek F., Mader, Pavel, St-Cyr, Daniel J., Pau, Victor, Kurinov, Igor, Tang, Xiaojing, Deng, Dongjing, Cui, Weiren, Su, Wenji, Kuai, Letian, Soll, Richard, Tyers, Mike, Röst, Hannes L., Batey, Robert A., Taipale, Mikko, Gingras, Anne-Claude, Sicheri, Frank

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Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15 von Teyra, Joan, Singer, Alex U., Schmitges, Frank W., Jaynes, Patrick, Kit Leng Lui, Sarah, Polyak, Maria J., Fodil, Nassima, Krieger, Jonathan R., Tong, Jiefei, Schwerdtfeger, Carsten, Brasher, Bradley B., Ceccarelli, Derek F.J., Moffat, Jason, Sicheri, Frank, Moran, Michael F., Gros, Philippe, Eichhorn, Pieter J.A., Lenter, Martin, Boehmelt, Guido, Sidhu, Sachdev S.

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The Skap-hom Dimerization and PH Domains Comprise a 3′-Phosphoinositide-Gated Molecular Switch von Swanson, Kenneth D., Tang, Yong, Ceccarelli, Derek F., Poy, Florence, Sliwa, Jan P., Neel, Benjamin G., Eck, Michael J.

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