EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway von Bonavia, R, Inda, M M, Vandenberg, S, Cheng, S-Y, Nagane, M, Hadwiger, P, Tan, P, Sah, D W Y, Cavenee, W K, Furnari, F B

Volltext

Disruption of Forkhead Transcription Factor (FOXO) Family Members in Mice Reveals Their Functional Diversification von Hosaka, Taisuke, Biggs, William H., Tieu, David, Boyer, Antonia D., Varki, Nissi M., Cavenee, Webster K., Arden, Karen C., White, Raymond L.

Volltext

A Global Transcriptional Regulatory Role for c-Myc in Burkitt's Lymphoma Cells von Li, Zirong, Van Calcar, Sara, Qu, Chunxu, Cavenee, Webster K., Zhang, Michael Q., Ren, Bing

Volltext

The WHO Classification of Tumors of the Nervous System von KLEIHUES, PAUL, LOUIS, DAVID N, SCHEITHAUER, BERND W, RORKE, LUCY B, REIFENBERGER, GUIDO, BURGER, PETER C, CAVENEE, WEBSTER K

Volltext

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors von Mellinghoff, Ingo K, Wang, Maria Y, Vivanco, Igor, Haas-Kogan, Daphne A, Zhu, Shaojun, Dia, Ederlyn Q, Lu, Kan V, Yoshimoto, Koji, Huang, Julie H.Y, Chute, Dennis J, Riggs, Bridget L, Horvath, Steve, Liau, Linda M, Cavenee, Webster K, Rao, P. Nagesh, Beroukhim, Rameen, Peck, Timothy C, Lee, Jeffrey C, Sellers, William R, Stokoe, David, Prados, Michael, Cloughesy, Timothy F, Sawyers, Charles L, Mischel, Paul S

Volltext

Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1 von Nakae, Jun, Biggs, William H., Kitamura, Tadahiro, Cavenee, Webster K., Wright, Christopher V.E., Arden, Karen C., Accili, Domenico

Volltext

Malignant glioma: genetics and biology of a grave matter von Maher, E A, Furnari, F B, Bachoo, R M, Rowitch, D H, Louis, D N, Cavenee, W K, DePinho, R A

Volltext

Protein Kinase B/Akt-Mediated Phosphorylation Promotes Nuclear Exclusion of the Winged Helix Transcription Factor FKHR1 von Biggs, William H., Meisenhelder, Jill, Hunter, Tony, Cavenee, Webster K., Arden, Karen C.

Volltext

Platelet-Derived Growth Factor-B Enhances Glioma Angiogenesis by Stimulating Vascular Endothelial Growth Factor Expression in Tumor Endothelia and by Promoting Pericyte Recruitment von Guo, Ping, Hu, Bo, Gu, Weisong, Xu, Li, Wang, Degui, Huang, Hui-Jen Su, Cavenee, Webster K., Cheng, Shi-Yuan

Volltext

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vi... von NAGANE, M, GUOHUA PAN, WEDDLE, J. J, DIXIT, V. M, CAVENEE, W. K, HUANG, H.-J. S

Volltext

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns von Costello, Joseph F., Frühwald, Michael C., Smiraglia, Dominic J., Rush, Laura J., Robertson, Gavin P., Gao, Xin, Wright, Fred A., Feramisco, Jamison D., Peltomäki, Päivi, Lang, James C., Schuller, David E., Yu, Li, Bloomfield, Clara D., Caligiuri, Michael A., Yates, Allan, Nishikawa, Ryo, Su Huang, H.-J., Petrelli, Nicholas J., Zhang, Xueli, O'Dorisio, M. S., Held, William A., Cavenee, Webster K., Plass, Christoph

Volltext

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers i... von Goudar, Ranjit K, Shi, Qing, Hjelmeland, Mark D, Keir, Stephen T, McLendon, Roger E, Wikstrand, Carol J, Reese, Elizabeth D, Conrad, Charles A, Traxler, Peter, Lane, Heidi A, Reardon, David A, Cavenee, Webster K, Wang, Xiao-Fan, Bigner, Darell D, Friedman, Henry S, Rich, Jeremy N

Volltext

Cellular Transformation by the MSP58 Oncogene Is Inhibited by Its Physical Interaction with the PTEN Tumor Suppressor von Okumura, Koichi, Zhao, Mujun, DePinho, Ronald A., Furnari, Frank B., Cavenee, Webster K.

Volltext

Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/akt pathway in glioblastomas von NARITA, Yoshitaka, NAGANE, Motoo, MISHIMA, Kazuhiko, HUANG, H-J. Su, FURNARI, Frank B, CAVENEE, Webster K

Volltext

Growth Suppression of Glioma Cells by PTEN Requires a Functional Phosphatase Catalytic Domain von Furnari, Frank B., Lin, Hong, H.-J. Su Huang, Cavenee, Webster K.

Volltext

Epidermal Growth Factor Receptor Signaling Intensity Determines Intracellular Protein Interactions, Ubiquitination, and Internalization von Mirko H. H. Schmidt, Furnari, Frank B., Cavenee, Webster K., Bögler, Oliver

Volltext

Methylation-associated silencing of the tissue inhibitor of Metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers von BACHMAN, K. E, HERMAN, J. G, CORN, P. G, MERLO, A, COSTELLO, J. F, CAVENEE, W. K, BAYLIN, S. B, GRAFF, J. R

Volltext

Alix/AIP1 Antagonizes Epidermal Growth Factor Receptor Downregulation by the Cbl-SETA/CIN85 Complex von Schmidt, Mirko H H, Hoeller, Daniela, Yu, Jiuhong, Furnari, Frank B, Cavenee, Webster K, Dikic, Ivan, Bögler, Oliver

Volltext

Angiopoietin-2 Induces Human Glioma Invasion through the Activation of Matrix Metalloprotease-2 von Hu, Bo, Guo, Ping, Fang, Quan, Tao, Huo-Quan, Wang, Degui, Nagane, Motoo, Huang, Hui-Jein Su, Gunji, Yuji, Nishikawa, Ryo, Alitalo, Kari, Cavenee, Webster K., Cheng, Shi-Yuan

Volltext

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-X L and caspase-3-like proteases von Nagane, Motoo, Levitzki, Alexander, Gazit, Aviv, Cavenee, Webster K., Huang, H.-J. Su

Volltext