56P Efficacy and safety of nivolumab (Nivo) in recurrent and/or metastatic platinum-refractory squamous cell carcinoma of head and neck (R/M SCCHN): A real-world data study von Castillo, J.J. Soto, Villarrubia, J. Esteban, Ballesteros, P. Alvarez, Lopez, P. Garrido, Rivas, A. Soria

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429 (PB417): Lessons learned from a pan-cancer exploratory Liquid Biopsy (LB) profiling: the PREICO-LB project von Hierro, C., Notario, L., Bergamino, M., Sabat, P., Soto-Castillo, J.J., Calvo, M., Oliva, M., Jove, M., Ruffinelli, J.C., Mosteiro, M.A., de Olza, M. Ochoa, Carcereny, E., Balaña, D., Gonzalez, M.I., Fina, C., Gil-Martin, M., Nadal, E., Azuara, D., Lazaro, C., Martin-Liberal, J.

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406P Phase Ib safety and efficacy of nadunolimab/gemcitabine/carboplatin in mTNBC von Lopez-Tarruella Cobo, S., Stradella, A., Ortega, P. Tolosa, Antolín-Novoa, S., Eslava, M. Santisteban, Garcia-Corbacho, J., Guerrero Zotano, A.L., Borrego, M. Ruiz, Caffarel, M. Muñoz, Losic, N., Gyllenbäck, E. Jaensson, Skoog, P., Johansen Blanco, H., Soto-Castillo, J.J., Alva Bianchi, M., Rendo, C. Reboredo, Casas, M., Caparroso, N., Montes, S. Bezares, Ribas, I. Garcia

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1712P Implementation of a molecular pre-screening program (MPP) in a network of public cancer centres for phase I clinical trial (Ph1-CT) candidates: The PREICO program von Soto Castillo, J.J., Notario Rincon, L., Azuara, D., Ruffinelli, J.C., Stradella, A., Oliva Bernal, M., Calvo Campos, M., Jové, M., Llop Serna, S., Villanueva Vazquez, R., Cuadra Amor, C., Bergamino, M.A., Teixidor Vilà, E., Villatoro Gómez, S., González Acosta, M., Fina Planas, C., Hierro, C., Gil Martín, M., Lazaro, C., Martin-Liberal, J.

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125P Benefit of immunotherapy in advanced NSCLC patients selected by KRAS mutations: A single institute retrospective analysis von Castillo, J.J. Soto, de la Fuente, E. Corral, García, M.E. Olmedo, Rueda, A. Gómez, Lage, Y., Navas, E.M. Vida, Gómez, L. Sanz, Lario, M., Lopez, P. Garrido

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1117P Mutational landscape of large cell neuroendocrine lung carcinoma: Molecular characterization using next generation sequencing von San Roman-Gil, M., Sanz-Gómez, L., Chamorro-Pérez, J., Lage, Y., Garcia, M.E.O., Gomez, A., Corral de la Fuente, E., Rosero-Rodríguez, D.I., Albarrán Fernández, V., Pozas, J., Alvarez-Ballesteros, P., Vida-Navas, E.M., Soto-Castillo, J.J., Torres-Jiménez, J., Esteban-Villarrubia, J., Orejana-Martín, I., Benito Berlinches, A., Garrido Lopez, P.

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124P KRAS mutated (mt) non-small cell lung cancer (NSCLC) and response to antiPD-1/PD-L1 regarding co-mutational status and assessment of KRAS mutation on plasma or tissue biopsy von de la Fuente, E. Corral, Castillo, J.J. Soto, Rueda, A. Gómez, Lage, Y., García, M.E. Olmedo, Navas, E.M. Vida, Jiménez, J. Torres, Ballesteros, P. Álvarez, Lario, M., Berlinches, A. Benito, Lopez, P. Garrido

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6P Clinical and molecular characteristics in non-small cell lung cancer patients with alteration in PIK3 pathway von Lage, Y., Ballesteros, P. Álvarez, García, M.E. Olmedo, Rueda, A. Gómez, de la Fuente, E. Corral, Jiménez, J. Torres, Navas, E.M. Vida, Castillo, J.J. Soto, Lario, M., Berlinches, A. Benito, Santón, A., Lopez, P. Garrido

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1744P COVID-19 in cancer patients: Risk factors for the development of severe clinical event (SCE) von Serrano Domingo, J.J., Corral de la Fuente, E., Martin Huertas, R., Vida Navas, E.M., Soto Castillo, J.J., Sanz Gomez, L., Torres Jimenez, J., Esteban Villarrubia, J., Orejana Martin, I., Alvarez Ballesteros, P., Pozas Perez, J., San Roman Gil, M.V., Garrido Lopez, P., Carrato Mena, A.

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149P Assessing treatment options for gynaecological cancers (GC) using next-generation sequencing (NGS): A real-world analysis von García, Á.B., Sepulveda, Z. Vidales, Rubio, I. Ortiz, Martin-Liberal, J., Varela, M., Jamal, D. Najjari, Castillo, J.J. Soto, Viltró, P. Sàbat, Cardona, L. Marti, Stefanovic, M., Gómez, S. Villatoro, Búrdalo, B. Pardo, Martín, M. Gil

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218P Clinical characteristics and treatment outcomes in lung cancer patients with FGFR genes alterations von Jiménez, J. Torres, Villarrubia, J. Esteban, Navas, E.M. Vida, Castillo, J.J. Soto, Gómez, L. Sanz, Martín, I. Orejana, Ballesteros, P. Álvarez, Pérez, J. Pozas, Gil, M. San Román, Fernández, V. Albarrán, Pérez, J. Chamorro, Rodríguez, D.I. Rosero, Rueda, A. Gómez, de la Fuente, E. Corral, Lage, Y., Santón, A., Berlinches, A. Benito, Lario, M., García, M.E. Olmedo, Lopez, P. Garrido

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52P Genetic and clinical profiling of a cohort of extended small cell lung carcinoma von Navas, E.M. Vida, Pérez, J. Chamorro, de la Fuente, E. Corral, Lage, Y., Rueda, A. Gómez, Jiménez, J. Torres, Gómez, L. Sanz, Castillo, J.J. Soto, Ballesteros, P. Álvarez, Villarrubia, J. Esteban, Fernández, V. Albarrán, Rodríguez, D.I. Rosero, Gil, M. San Román, Pérez, J. Pozas, Lario, M., Lizarralde, A. Caminoa, Lopez, P. Garrido, García, M.E. Olmedo

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129P NGS prescreening program for refractory solid tumors outside standard indications in a public network of cancer centers von Viltró, P. Sàbat, Azuara, D., Castillo, J.J. Soto, Rincon, L. Notario, Calvo, M., Casulleras, M. Jové, Bernal, M. Oliva, Rodriguez, J.C. Ruffinelli, Stradella, A., Vazquez, R. Villanueva, Bergamino, M.A., Ochoa de Olza Amat, M., Gómez, S. Villatoro, Varela, M., Acosta, M. González, Planas, C. Fina, Hierro, C., Martín, M. Gil, Lazaro, C., Martin-Liberal, J.

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151P Unravelling the limitations of next-generation sequencing (NGS)-based liquid biopsy (LB) across solid tumors: The PREICO-LB project von Hierro, C., Rincon, L. Notario, Bergamino, M.A., Viltró, P. Sàbat, Castillo, J.J. Soto, Calvo, M., Bernal, M. Oliva, Casulleras, M. Jové, Rodriguez, J.C. Ruffinelli, Mosteiro, M-A., Ochoa de Olza Amat, M., Carcereny, E., Balaña, D., Acosta, M. González, Planas, C. Fina, Martín, M. Gil, Nadal, E., Azuara, D., Lazaro, C., Martin-Liberal, J.

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162P Tailoring patient molecular selection for novel anti-MET therapies von Rincon, L. Notario, Viltró, P. Sàbat, Castillo, J.J. Soto, Bergamino, M.A., Vinolas, M. Domenech, Calvo, M., Bernal, M. Oliva, Casulleras, M. Jové, Rodriguez, J.C. Ruffinelli, Ochoa de Olza Amat, M., Stradella, A., Carcereny, E., Balaña, D., Acosta, M. González, Planas, C. Fina, Martín, M. Gil, Azuara, D., Lazaro, C., Martin-Liberal, J., Hierro, C.

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209P The management of brain disease (BD) in ALK-rearranged non-small cell lung cancer (ALK NSCLC): Can systemic treatment delay the initiation of local treatments? Experience of t... von Huertas, R. Martin, Garcia, I. Ciscar, Serrano, C. Saavedra, Domingo, J.J. Serrano, de la Fuente, E. Corral, Castillo, J.J. Soto, Rueda, A. Gomez, Olmedo Garcia, M.E., Lopez, P. Garrido

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118O Definitive results for NSCLC and bladder cancer cohorts in the phase IIa trial of visugromab (CTL-002) in advanced/metastatic anti-PD/PD-L1 relapsed/refractory solid tumors (G... von Melero, I., De Miguel, M.J., Casal, G. Alonso, De Velasco Oria, G.A., Ramelyte, E., Joerger, M., Martin-Liberal, J., König, D., Sayehli, C.M., Gromke, T., RodrÍguez-Ruiz, M.E., Calvo, E., Garralda, E., Soto-Castillo, J.J., Dummer, R., Villarrubia, J. Esteban, Goebeler, M-E., Fettes, P., Klar, K., Leo, E.

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107P Unveiling mismatch repair deficiency (dMMR) and microsatellite-instability high (MSI-H) detection in cancer patients (pt) using a next-generation sequencing (NGS)-based molecu... von Rincon, L. Notario, Bergamino, M.A., Ochoa de Olza Amat, M., Carcereny, E., Urbizu, A., Muñoz-Mármol, A.M., Arnaldo, L., Azuara, D., Badosa, A. Alay, Matias-Guiu, X., Jimeno, M., Hernandez, A., Balaña, D., Planas, C. Fina, Martín, M. Gil, Castillo, J.J. Soto, Martin-Liberal, J., Lazaro, C., Sanz, C., Hierro, C.

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The management of brain disease (BD) in ALK-rearranged non-small cell lung cancer (ALK NSCLC): Can systemic treatment delay the initiation of local treatments? Experience of the Ra... von Huertas, Martin R, Garcia, Ciscar I, Serrano, Saavedra C, Domingo, Serrano J.J, de la Fuente, Corral E, Castillo, Soto J.J, Rueda, Gomez A, Garcia, Olmedo M.E, Lopez, Garrido P

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Contrasting propagule dispersal and halophyte seed banks along the intertidal gradient von Polo-Ávila, Alejandro, Infante-Izquierdo, María D., Soto, José M., Hermoso-López, Virgilio, Nieva, Francisco J. J., Castillo, Jesús M., Muñoz-Rodríguez, Adolfo F.

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