High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines von Li, Yilai, Cash, Jennifer N., Tesmer, John J.G., Cianfrocco, Michael A.

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Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibr... von Lu, Tsan-Wen, Aoto, Phillip C., Weng, Jui-Hung, Nielsen, Cole, Cash, Jennifer N., Hall, James, Zhang, Ping, Simon, Sanford M., Cianfrocco, Michael A., Taylor, Susan S.

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Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3 von Cash, Jennifer N., Davis, Ellen M., Tesmer, John J.G.

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Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 von Ravala, Sandeep K, Adame-Garcia, Sendi Rafael, Li, Sheng, Chen, Chun-Liang, Cianfrocco, Michael A, Silvio Gutkind, J, Cash, Jennifer N, Tesmer, John JG

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High-resolution cryo-EM using beam-image shift at 200 keV von Cash, Jennifer N., Kearns, Sarah, Li, Yilai, Cianfrocco, Michael A.

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Cryo-electron microscopy structure and analysis of the P-Rex1-Gβγ signaling scaffold von Cash, Jennifer N, Urata, Sarah, Li, Sheng, Ravala, Sandeep K, Avramova, Larisa V, Shost, Michael D, Gutkind, J Silvio, Tesmer, John J G, Cianfrocco, Michael A

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Structural and biochemical characterization of the pleckstrin homology domain of the RhoGEF P-Rex2 and its regulation by PIP3 von Cash, Jennifer N., Sharma, Prateek V., Tesmer, John J.G.

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New insights into regulation of P‐Rex1 autoinhibition von Ravala, Sandeep Kaur, Li, Sheng, Chen, Chun‐Liang, Cianfrocco, Michael A., Cash, Jennifer N., Tesmer, John J. G.

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Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1 von Bandekar, Sumit J., Chen, Chun-Liang, Ravala, Sandeep K., Cash, Jennifer N., Avramova, Larisa V., Zhalnina, Mariya V., Gutkind, J. Silvio, Li, Sheng, Tesmer, John J.G.

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The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding von Ravala, Sandeep K., Hopkins, Jesse B., Plescia, Caroline B., Allgood, Samantha R., Kane, Madison A., Cash, Jennifer N., Stahelin, Robert V., Tesmer, John J.G.

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Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP3)-Dependent Rac Exchanger 1 (P-Rex1) PIP3-Binding Site and Inhibit P-Rex1–Dependent Fun... von Cash, Jennifer N., Chandan, Naincy R., Hsu, Alan Y., Sharma, Prateek V., Deng, Qing, Smrcka, Alan V., Tesmer, John J.G.

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The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding von Cash, Jennifer N, Rejon, Carlis A, McPherron, Alexandra C, Bernard, Daniel J, Thompson, Thomas B

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Structure of myostatin·follistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding von Cash, Jennifer N, Angerman, Elizabeth B, Kattamuri, Chandramohan, Nolan, Kristof, Zhao, Huaying, Sidis, Yisrael, Keutmann, Henry T, Thompson, Thomas B

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Discovery of Small Molecules That Target the Phosphatidylinositol (3,4,5) Trisphosphate (PIP 3 )-Dependent Rac Exchanger 1 (P-Rex1) PIP 3 -Binding Site and Inhibit P-Rex1-Dependent... von Cash, Jennifer N, Chandan, Naincy R, Hsu, Alan Y, Sharma, Prateek V, Deng, Qing, Smrcka, Alan V, Tesmer, John J G

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Characterization of Follistatin-Type Domains and Their Contribution to Myostatin and Activin A Antagonism von Cash, Jennifer N, Angerman, Elizabeth B, Keutmann, Henry T, Thompson, Thomas B

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Structural Snapshots of a Dynamic Process in the Regulation of P-Rex, a Metastatic Factor von Cash, Jennifer N., Ravala, Sandeep, Tesmer, John J.G., Cianfrocco, Michael A.

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Development of a Small-Molecule Screening Method for Inhibitors of Cellular Response to Myostatin and Activin A von Cash, Jennifer N., Angerman, Elizabeth B., Kirby, R. Jason, Merck, Lisa, Seibel, William L., Wortman, Matthew D., Papoian, Ruben, Nelson, Sandra, Thompson, Thomas B.

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Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 von Ravala, Sandeep K, Adame-Garcia, Sendi Rafael, Li, Sheng, Chen, Chun-Liang, Cianfrocco, Michael A, Silvio Gutkind, J, Cash, Jennifer N, Tesmer, John JG

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Structural and Functional Characterization of the Metastatic RhoGEF P‐Rex1 and its Regulation by PtdIns(3,4,5) P 3 : Towards Inhibitory Small Molecule Development von Cash, Jennifer N., Davis, Ellen M., Tesmer, John J.G.

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Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P[subscript 3] von Cash, Jennifer N., Davis, Ellen M., Tesmer, John J.G.

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