The in vitro genotoxicity of orthopaedic ceramic (Al2O3) and metal (CoCr alloy) particles von Tsaousi, Aikaterini, Jones, Eric, Case, Charles P.

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Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity von Raghunathan, Vijay Krishna, Devey, Michael, Hawkins, Sue, Hails, Lauren, Davis, Sean A, Mann, Stephen, Chang, Isaac T, Ingham, Eileen, Malhas, Ashraf, Vaux, David J, Lane, Jon D, Case, Charles P

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Thresholds for indirect DNA damage across cellular barriers for orthopaedic biomaterials von Parry, Michael C, Bhabra, Gevdeep, Sood, Aman, Machado, Filipa, Cartwright, Laura, Saunders, Margaret, Ingham, E, Newson, R, Blom, Ashley W, Case, Charles P

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Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators von Hubbard, Basil P., Gomes, Ana P., Dai, Han, Li, Jun, Case, April W., Considine, Thomas, Riera, Thomas V., Lee, Jessica E., Yen E, Sook, Lamming, Dudley W., Pentelute, Bradley L., Schuman, Eli R., Stevens, Linda A., Ling, Alvin J. Y., Armour, Sean M., Michan, Shaday, Zhao, Huizhen, Jiang, Yong, Sweitzer, Sharon M., Blum, Charles A., Disch, Jeremy S., Ng, Pui Yee, Howitz, Konrad T., Rolo, Anabela P., Hamuro, Yoshitomo, Moss, Joel, Perni, Robert B., Ellis, James L., Vlasuk, George P., Sinclair, David A.

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In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains von Chen, Rita E., Winkler, Emma S., Case, James Brett, Aziati, Ishmael D., Bricker, Traci L., Joshi, Astha, Darling, Tamarand L., Ying, Baoling, Errico, John M., Shrihari, Swathi, VanBlargan, Laura A., Xie, Xuping, Gilchuk, Pavlo, Zost, Seth J., Droit, Lindsay, Liu, Zhuoming, Stumpf, Spencer, Wang, David, Handley, Scott A., Stine, W. Blaine, Shi, Pei-Yong, Davis-Gardner, Meredith E., Suthar, Mehul S., Knight, Miguel Garcia, Andino, Raul, Chiu, Charles Y., Ellebedy, Ali H., Fremont, Daved H., Whelan, Sean P. J., Crowe, James E., Purcell, Lisa, Corti, Davide, Boon, Adrianus C. M., Diamond, Michael S.

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Simulating the Motion Underlying the Mechanism of Thioredoxin Reductase von Zuiderweg, Erik R.P., Case, David A., Williams, Charles H.

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ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response von Adeyemo, Adebowale A., Zaghloul, Norann A., Chen, Guanjie, Doumatey, Ayo P., Leitch, Carmen C., Hostelley, Timothy L., Nesmith, Jessica E., Zhou, Jie, Bentley, Amy R., Shriner, Daniel, Fasanmade, Olufemi, Okafor, Godfrey, Eghan, Benjamin, Agyenim-Boateng, Kofi, Chandrasekharappa, Settara, Adeleye, Jokotade, Balogun, William, Owusu, Samuel, Amoah, Albert, Acheampong, Joseph, Johnson, Thomas, Oli, Johnnie, Adebamowo, Clement, Collins, Francis, Dunston, Georgia, Rotimi, Charles N.

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Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility von Patsopoulos, Nikolaos A., Baranzini, Sergio E., Santaniello, Adam, Shoostari, Parisa, Cotsapas, Chris, Wong, Garrett, Beecham, Ashley H., James, Tojo, Replogle, Joseph, Vlachos, Ioannis S., McCabe, Cristin, Pers, Tune H., Brandes, Aaron, White, Charles, Keenan, Brendan, Cimpean, Maria, Winn, Phoebe, Panteliadis, Ioannis-Pavlos, Robbins, Allison, Andlauer, Till F. M., Zarzycki, Onigiusz, Dubois, Bénédicte, Goris, An, Søndergaard, Helle Bach, Sellebjerg, Finn, Sorensen, Per Soelberg, Ullum, Henrik, Thørner, Lise Wegner, Saarela, Janna, Cournu-Rebeix, Isabelle, Damotte, Vincent, Fontaine, Bertrand, Guillot-Noel, Lena, Lathrop, Mark, Vukusic, Sandra, Berthele, Achim, Pongratz, Viola, Buck, Dorothea, Gasperi, Christiane, Graetz, Christiane, Grummel, Verena, Hemmer, Bernhard, Hoshi, Muni, Knier, Benjamin, Korn, Thomas, Lill, Christina M., Luessi, Felix, Mühlau, Mark, Zipp, Frauke, Dardiotis, Efthimios, Agliardi, Cristina, Amoroso, Antonio, Barizzone, Nadia, Benedetti, Maria D., Bernardinelli, Luisa, Cavalla, Paola, Clarelli, Ferdinando, Comi, Giancarlo, Cusi, Daniele, Esposito, Federica, Ferrè, Laura, Galimberti, Daniela, Guaschino, Clara, Leone, Maurizio A., Martinelli, Vittorio, Moiola, Lucia, Salvetti, Marco, Sorosina, Melissa, Vecchio, Domizia, Zauli, Andrea, Santoro, Silvia, Mancini, Nicasio, Zuccalà, Miriam, Mescheriakova, Julia, van Duijn, Cornelia, Bos, Steffan D., Celius, Elisabeth G., Spurkland, Anne, Comabella, Manuel, Montalban, Xavier, Alfredsson, Lars, Bomfim, Izaura L., Gomez-Cabrero, David, Hillert, Jan, Jagodic, Maja, Lindén, Magdalena, Piehl, Fredrik, Jelčić, Ilijas, Martin, Roland, Sospedra, Mirela, Baker, Amie, Ban, Maria, Hawkins, Clive, Hysi, Pirro, Kalra, Seema, Karpe, Fredrik, Khadake, Jyoti, Lachance, Genevieve, Molyneux, Paul, Neville, Matthew

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Crystallographic structure of a small molecule SIRT1 activator-enzyme complex von Dai, Han, Case, April W., Riera, Thomas V., Considine, Thomas, Lee, Jessica E., Hamuro, Yoshitomo, Zhao, Huizhen, Jiang, Yong, Sweitzer, Sharon M., Pietrak, Beth, Schwartz, Benjamin, Blum, Charles A., Disch, Jeremy S., Caldwell, Richard, Szczepankiewicz, Bruce, Oalmann, Christopher, Yee Ng, Pui, White, Brian H., Casaubon, Rebecca, Narayan, Radha, Koppetsch, Karsten, Bourbonais, Francis, Wu, Bo, Wang, Junfeng, Qian, Dongming, Jiang, Fan, Mao, Cheney, Wang, Minghui, Hu, Erding, Wu, Joe C., Perni, Robert B., Vlasuk, George P., Ellis, James L.

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Origins and functional impact of copy number variation in the human genome von Conrad, Donald F., Pinto, Dalila, Redon, Richard, Feuk, Lars, Gokcumen, Omer, Zhang, Yujun, Aerts, Jan, Andrews, T. Daniel, Barnes, Chris, Campbell, Peter, Fitzgerald, Tomas, Hu, Min, Ihm, Chun Hwa, Kristiansson, Kati, MacArthur, Daniel G., MacDonald, Jeffrey R., Onyiah, Ifejinelo, Pang, Andy Wing Chun, Robson, Sam, Stirrups, Kathy, Valsesia, Armand, Walter, Klaudia, Wei, John, Tyler-Smith, Chris, Carter, Nigel P., Lee, Charles, Scherer, Stephen W., Hurles, Matthew E.

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Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region von Barrett, Jeffrey C, Lee, James C, Lees, Charles W, Prescott, Natalie J, Anderson, Carl A, Phillips, Anne, Wesley, Emma, Parnell, Kirstie, Zhang, Hu, Drummond, Hazel, Nimmo, Elaine R, Massey, Dunecan, Blaszczyk, Kasia, Elliott, Timothy, Cotterill, Lynn, Dallal, Helen, Lobo, Alan J, Mowat, Craig, Sanderson, Jeremy D, Jewell, Derek P, Newman, William G, Edwards, Cathryn, Ahmad, Tariq, Mansfield, John C, Satsangi, Jack, Parkes, Miles, Mathew, Christopher G, Donnelly, Peter, Peltonen, Leena, Blackwell, Jenefer M, Bramon, Elvira, Brown, Matthew A, Casas, Juan P, Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S, McCarthy, Mark I, Palmer, Colin N A, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Samani, Nilesh, Trembath, Richard C, Viswanathan, Anath C, Wood, Nicholas, Spencer, Chris C A, Bellenguez, Céline, Davison, Daniel, Freeman, Colin, Strange, Amy, Langford, Cordelia, Hunt, Sarah E, Edkins, Sarah, Gwilliam, Rhian, Blackburn, Hannah, Bumpstead, Suzannah J, Dronov, Serge, Gillman, Matthew, Gray, Emma, Hammond, Naomi, Jayakumar, Alagurevathi, McCann, Owen T, Liddle, Jennifer, Perez, Marc L, Potter, Simon C, Ravindrarajah, Radhi, Ricketts, Michelle, Waller, Matthew, Weston, Paul, Widaa, Sara, Whittaker, Pamela, Attwood, Antony P, Stephens, Jonathan, Sambrook, Jennifer, Ouwehand, Willem H, McArdle, Wendy L, Ring, Susan M, Strachan, David P

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Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis von Mells, George F, Floyd, James A B, Morley, Katherine I, Cordell, Heather J, Franklin, Christopher S, Shin, So-Youn, Heneghan, Michael A, Neuberger, James M, Donaldson, Peter T, Day, Darren B, Ducker, Samantha J, Muriithi, Agnes W, Wheater, Elizabeth F, Hammond, Christopher J, Dawwas, Muhammad F, Jones, David E, Peltonen, Leena, Alexander, Graeme J, Sandford, Richard N, Anderson, Carl A

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Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy von Finkel, Richard S, Mercuri, Eugenio, Darras, Basil T, Connolly, Anne M, Kuntz, Nancy L, Kirschner, Janbernd, Chiriboga, Claudia A, Saito, Kayoko, Servais, Laurent, Tizzano, Eduardo, Topaloglu, Haluk, Tulinius, Már, Montes, Jacqueline, Glanzman, Allan M, Bishop, Kathie, Zhong, Z. John, Gheuens, Sarah, Bennett, C. Frank, Schneider, Eugene, Farwell, Wildon, De Vivo, Darryl C

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Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol von Ray, Kausik K, Bays, Harold E, Catapano, Alberico L, Lalwani, Narendra D, Bloedon, LeAnne T, Sterling, Lulu R, Robinson, Paula L, Ballantyne, Christie M

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Integrated genomic characterization of oesophageal carcinoma von Reis, R. M., The Cancer Genome Atlas Research Network

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Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Ci... von Sabater-Lleal, Maria, Huang, Jie, Chasman, Daniel, Naitza, Silvia, Dehghan, Abbas, Teumer, Alexander, Folkersen, Lasse, Basu, Saonli, Rudnicka, Alicja R., Trompet, Stella, Mälarstig, Anders, Baumert, Jens, Guo, Xiuqing, Hottenga, Jouke J., Shin, So-Youn, Lopez, Lorna M., Lahti, Jari, Oudot-Mellakh, Tiphaine, Wilson, James F., Navarro, Pau, Huffman, Jennifer E., Zemunik, Tatijana, Mehra, Reena, Rudan, Igor, Wright, Alan F., Campbell, Harry, Wallace, Robert, Liu, Simin, Eaton, Charles B., Becker, Diane M., Becker, Lewis C., Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Fornage, Myriam, Green, David, Gross, Myron, Harris, Sarah E., Starr, John M., Williams, Frances M.K., Spector, Timothy D., Strawbridge, Rona J., Silveira, Angela, Sennblad, Bengt, Uitterlinden, Andre G., Franco, Oscar H., Hofman, Albert, van Dongen, Jenny, Yao, Jie, Swords Jenny, Nancy, Haritunians, Talin, Lumley, Thomas, Taylor, Kent D., Peters, Annette, Illig, Thomas, Kocher, Thomas, Franzosi, Maria Grazia, Seedorf, Udo, Clarke, Robert, Schlessinger, David, Stott, David J., Sattar, Naveed, Buckley, Brendan M., Lowe, Gordon D., Chen, Ming-Huei, Tofler, Geoffrey H., Song, Jaejoon, Boerwinkle, Eric, Rose, Lynda M., Franco-Cereceda, Anders, Teichert, Martina, Mosley, Thomas H., Bevan, Steve, Dichgans, Martin, Sudlow, Cathie L.M., Hopewell, Jemma C., Chambers, John C., Saleheen, Danish, Kooner, Jaspal S., Danesh, John, Nelson, Christopher P., Reilly, Muredach P., Kathiresan, Sekar, Schunkert, Heribert, Morange, Pierre-Emmanuel, Ferrucci, Luigi, Eriksson, Johan G., Jacobs, David, Deary, Ian J., Soranzo, Nicole, Tracy, Russell P., Hayward, Caroline, Koenig, Wolfgang, Cucca, Francesco, Samani, Nilesh J., Smith, Nicholas L., Ridker, Paul M, Tang, Weihong, Hamsten, Anders, O’Donnell, Christopher J.

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Assessment of serological assays for identifying high titer convalescent plasma von Farnsworth, Christopher W., Case, James B., Hock, Karl, Chen, Rita E., O'Halloran, Jane A., Presti, Rachel, Goss, Charles W., Rauseo, Adriana M., Ellebedy, Ali, Theel, Elitza S., Diamond, Michael S., Henderson, Jeffrey P.

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The correlation between reading and mathematics ability at age twelve has a substantial genetic component von Davis, Oliver S. P., Band, Gavin, Pirinen, Matti, Haworth, Claire M. A., Meaburn, Emma L., Kovas, Yulia, Harlaar, Nicole, Docherty, Sophia J., Hanscombe, Ken B., Trzaskowski, Maciej, Curtis, Charles J. C., Strange, Amy, Freeman, Colin, Bellenguez, Céline, Su, Zhan, Pearson, Richard, Vukcevic, Damjan, Langford, Cordelia, Deloukas, Panos, Hunt, Sarah, Gray, Emma, Dronov, Serge, Potter, Simon C., Tashakkori-Ghanbaria, Avazeh, Edkins, Sarah, Bumpstead, Suzannah J., Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz A. Z., Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N. A., Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Barroso, Ines, Peltonen, Leena, Dale, Philip S., Petrill, Stephen A., Schalkwyk, Leonard S., Craig, Ian W., Lewis, Cathryn M., Price, Thomas S., Donnelly, Peter, Plomin, Robert, Spencer, Chris C. A.

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Genome-wide association study identifies eight loci associated with blood pressure von Newton-Cheh, Christopher, Johnson, Toby, Gateva, Vesela, Tobin, Martin D, Coin, Lachlan, Zhao, Jing Hua, Zhang, Feng, Farrall, Martin, Tanaka, Toshiko, Wallace, Chris, Chambers, John C, Khaw, Kay-Tee, van der Harst, Pim, Polidoro, Silvia, Elliott, Katherine S, Teumer, Alexander, Luan, Jian'an, Kuusisto, Johanna, Hadley, David, McArdle, Wendy L, Dominiczak, Anna, Samani, Nilesh J, Webster, John, Beckmann, Jacques S, Bergmann, Sven, Lim, Noha, Song, Kijoung, Vollenweider, Peter, Waeber, Gerard, Waterworth, Dawn M, Yuan, Xin, Orho-Melander, Marju, Allione, Alessandra, Di Gregorio, Alessandra, Guarrera, Simonetta, Panico, Salvatore, Barroso, Inês, Sandhu, Manjinder S, Luben, Robert N, Crawford, Gabriel J, Jousilahti, Pekka, Perola, Markus, Bonnycastle, Lori L, Collins, Francis S, Jackson, Anne U, Stringham, Heather M, Valle, Timo T, Bergman, Richard N, Gieger, Christian, Illig, Thomas, Kathiresan, Sekar, O'Donnell, Christopher J, Subirana, Isaac, Freimer, Nelson B, O'Reilly, Paul F, Peltonen, Leena, Pouta, Anneli, de Jong, Paul E, Snieder, Harold, van Gilst, Wiek H, Clarke, Robert, Hamsten, Anders, Peden, John F, Seedorf, Udo, Lakatta, Edward G, Sanna, Serena, Scuteri, Angelo, Dörr, Marcus, Ernst, Florian, Felix, Stephan B, Homuth, Georg, Gut, Ivo G, Lathrop, G Mark, Zelenika, Diana, Deloukas, Panos, Soranzo, Nicole, Williams, Frances M, Salomaa, Veikko, Laakso, Markku, Elosua, Roberto, Forouhi, Nita G, Völzke, Henry, Uiterwaal, Cuno S, van der Schouw, Yvonne T, Matullo, Giuseppe, Navis, Gerjan, Berglund, Göran, Kooner, Jaspal S, Bandinelli, Stefania, Watkins, Hugh, Tuomilehto, Jaakko, Altshuler, David, Laan, Maris, Meneton, Pierre, Jarvelin, Marjo-Riitta, Mooser, Vincent, Melander, Olle, Elliott, Paul, Caulfield, Mark, Munroe, Patricia B

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls von Clayton, David G, Cardon, Lon R, Duncanson, Audrey, Ouwehand, Willem H, Todd, John A, Donnelly, Peter, Easton, Doug, Evans, David, Morris, Andrew P, Spencer, Chris C. A, Boorman, James P, Cant, Barbara, Everson, Ursula, Hussey, Judith M, Knight, Alexandra S, Nutland, Sarah, Stevens, Helen E, Watkins, Nicholas A, Jones, Richard W, Ring, Susan M, Breen, Gerome, Caesar, Sian, Green, Elaine K, Grozeva, Detelina, Jones, Ian R, Kirov, George, Moskvina, Valentina, Nikolov, Ivan, Collier, David A, Farmer, Anne, Williamson, Richard, Young, Allan H, Ball, Stephen G, Balmforth, Anthony J, Bishop, D. Timothy, Iles, Mark M, Dixon, Richard J, Stevens, Suzanne, Thompson, John R, Bredin, Francesca, Tremelling, Mark, Drummond, Hazel, Nimmo, Elaine R, Fisher, Sheila A, Forbes, Alastair, Lewis, Cathryn M, Prescott, Natalie J, Barbour, Jamie, Mohiuddin, M. Khalid, Mansfield, John C, Cummings, Fraser R, Connell, John, Dobson, Richard, Gungadoo, Johannie, Newhouse, Stephen J, Barton, Anne, Bruce, Ian N, John, Sally L, Potter, Catherine, Silman, Alan J, Symmons, Deborah P. M, Dunger, David B, Widmer, Barry, Frayling, Timothy M, Lango, Hana, Perry, John R. B, Groves, Christopher J, Rayner, Nigel W, Timpson, Nicholas J, Zeggini, Eleftheria, Newport, Melanie, Vannberg, Fredrik, Farrar, Claire, Wordsworth, Paul, Brown, Matthew A, Franklyn, Jayne A, Heward, Joanne M, Simmonds, Matthew J, Seal, Sheila, Stratton, Michael R, Ban, Maria, Conway, David, Chaney, Amy, Ghori, Mohammed J. R, Gwilliam, Rhian, Hunt, Sarah E, McGinnis, Ralph, Potter, Simon, Whittaker, Pamela, Widden, Claire, Withers, David, Hallgrimsdottir, Ingileif B, Vukcevic, Damjan, Bentley, David, Caulfield, Mark, Compston, Alistair, Farrall, Martin, Hall, Alistair S, Hattersley, Andrew T, Mathew, Christopher G

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