Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants von Parker, Stephen C. J., Stitzel, Michael L., Taylor, D. Leland, Orozco, Jose Miguel, Erdos, Michael R., Akiyama, Jennifer A., van Bueren, Kelly Lammerts, Chines, Peter S., Narisu, Narisu, Black, Brian L., Visel, Axel, Pennacchio, Len A., Collins, Francis S.

Volltext

Genetic regulatory signatures underlying islet gene expression and type 2 diabetes von Varshney, Arushi, Scott, Laura J., Welch, Ryan P., Erdos, Michael R., Chines, Peter S., Narisu, Narisu, Albanus, Ricardo D’O., Orchard, Peter, Wolford, Brooke N., Kursawe, Romy, Vadlamudi, Swarooparani, Cannon, Maren E., Didion, John P., Hensley, John, Kirilusha, Anthony, Bonnycastle, Lori L., Taylor, D. Leland, Watanabe, Richard, Mohlke, Karen L., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J., Stitzel, Michael L.

Volltext

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection von Wu, Xueling, Zhang, Zhenhai, Schramm, Chaim A, Joyce, M Gordon, Kwon, Young Do, Zhou, Tongqing, Sheng, Zizhang, Zhang, Baoshan, O'Dell, Sijy, McKee, Krisha, Georgiev, Ivelin S, Chuang, Gwo-Yu, Longo, Nancy S, Lynch, Rebecca M, Saunders, Kevin O, Soto, Cinque, Srivatsan, Sanjay, Yang, Yongping, Bailer, Robert T, Louder, Mark K, Mullikin, James C, Connors, Mark, Kwong, Peter D, Mascola, John R, Shapiro, Lawrence

Volltext

Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions von Saheb Kashaf, Sara, Proctor, Diana M., Deming, Clay, Saary, Paul, Hölzer, Martin, Taylor, Monica E., Kong, Heidi H., Segre, Julia A., Almeida, Alexandre, Finn, Robert D.

Volltext

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma von Gartner, Jared J., Parker, Stephen C. J., Prickett, Todd D., Dutton-Regester, Ken, Stitzel, Michael L., Lin, Jimmy C., Davis, Sean, Simhadri, Vijaya L., Jha, Sujata, Katagiri, Nobuko, Gotea, Valer, Teer, Jamie K., Wei, Xiaomu, Morken, Mario A., Bhanot, Umesh K., Chen, Guo, Elnitski, Laura L., Davies, Michael A., Gershenwald, Jeffrey E., Carter, Hannah, Karchin, Rachel, Robinson, William, Robinson, Steven, Rosenberg, Steven A., Collins, Francis S., Parmigiani, Giovanni, Komar, Anton A., Kimchi-Sarfaty, Chava, Hayward, Nicholas K., Margulies, Elliott H., Samuels, Yardena

Volltext

Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains von Zhu, Jiang, Ofek, Gilad, Yang, Yongping, Zhang, Baoshan, Louder, Mark K., Lu, Gabriel, McKee, Krisha, Pancera, Marie, Skinner, Jeff, Zhang, Zhenhai, Parks, Robert, Eudailey, Joshua, Lloyd, Krissey E., Blinn, Julie, Alam, S. Munir, Haynes, Barton F., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Mullikin, James C., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.

Volltext

Circadian changes in long noncoding RNAs in the pineal gland von Coon, Steven L, Munson, Peter J, Cherukuri, Praveen F, Sugden, David, Rath, Martin F, Møller, Morten, Clokie, Samuel J. H, Fu, Cong, Olanich, Mary E, Rangel, Zoila, Werner, Thomas, Mullikin, James C, Klein, David C, Benjamin, Betty, Blakesley, Robert, Bouffard, Gerry, Brooks, Shelise, Chu, Grace, Coleman, Holly, Dekhtyar, Mila, Gregory, Michael, Guan, Xiaobin, Gupta, Jyoti, Han, Joel, Hargrove, April, Ho, Shi-ling, Johnson, Taccara, Legaspi, Richelle, Lovett, Sean, Maduro, Quino, Masiello, Cathy, Maskeri, Baishali, McDowell, Jenny, Montemayor, Casandra, Novotny, Betsy, Park, Morgan, Riebow, Nancy, Schandler, Karen, Schmidt, Brian, Sison, Christina, Stantripop, Mal, Thomas, James, Vemulapalli, Meg, Young, Alice

Volltext

Specific inactivation of two immunomodulatory SIGLEC genes during human evolution von Wang, Xiaoxia, Mitra, Nivedita, Secundino, Ismael, Banda, Kalyan, Cruz, Pedro, Padler-Karavani, Vered, Verhagen, Andrea, Reid, Chris, Lari, Martina, Rizzi, Ermanno, Balsamo, Carlotta, Corti, Giorgio, De Bellis, Gianluca, Longo, Laura, Beggs, William, Caramelli, David, Tishkoff, Sarah A, Hayakawa, Toshiyuki, Green, Eric D, Mullikin, James C, Nizet, Victor, Bui, Jack, Varki, Ajit, Benjamin, Betty, Blakesley, Robert, Bouffard, Gerry, Brooks, Shelise, Chu, Grace, Coleman, Holly, Dekhtyar, Mila, Gregory, Michael, Guan, Xiaobin, Gupta, Jyoti, Han, Joel, Hargrove, April, Ho, Shi-ling, Johnson, Taccara, Legaspi, Richelle, Lovett, Sean, Maduro, Quino, Masiello, Cathy, Maskeri, Baishali, McDowell, Jenny, Montemayor, Casandra, Novotny, Betsy, Park, Morgan, Riebow, Nancy, Schandler, Karen, Schmidt, Brian, Sison, Christina, Stantripop, Mal, Thomas, James, Vemulapalli, Meg, Young, Alice

Volltext

A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation von Pei, Wuhong, Xu, Lisha, Chen, Zelin, Slevin, Claire C., Pettie, Kade P., Wincovitch, Stephen, Burgess, Shawn M.

Volltext

Biogeography and individuality shape function in the human skin metagenome von Oh, Julia, Byrd, Allyson L., Deming, Clay, Conlan, Sean, Kong, Heidi H., Segre, Julia A.

Volltext

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies von Doria-Rose, Nicole A., Schramm, Chaim A., Gorman, Jason, Moore, Penny L., Bhiman, Jinal N., DeKosky, Brandon J., Ernandes, Michael J., Georgiev, Ivelin S., Kim, Helen J., Pancera, Marie, Staupe, Ryan P., Altae-Tran, Han R., Bailer, Robert T., Crooks, Ema T., Cupo, Albert, Druz, Aliaksandr, Garrett, Nigel J., Hoi, Kam H., Kong, Rui, Louder, Mark K., Longo, Nancy S., McKee, Krisha, Nonyane, Molati, O’Dell, Sijy, Roark, Ryan S., Rudicell, Rebecca S., Schmidt, Stephen D., Sheward, Daniel J., Soto, Cinque, Wibmer, Constantinos Kurt, Yang, Yongping, Zhang, Zhenhai, Mullikin, James C., Binley, James M., Sanders, Rogier W., Wilson, Ian A., Moore, John P., Ward, Andrew B., Georgiou, George, Williamson, Carolyn, Abdool Karim, Salim S., Morris, Lynn, Kwong, Peter D., Shapiro, Lawrence, Mascola, John R.

Volltext

Integrated genomic, epidemiologic investigation of Candida auris skin colonization in a skilled nursing facility von Proctor, Diana M., Dangana, Thelma, Sexton, D. Joseph, Fukuda, Christine, Yelin, Rachel D., Stanley, Mary, Bell, Pamela B., Baskaran, Sangeetha, Deming, Clay, Chen, Qiong, Conlan, Sean, Park, Morgan, Welsh, Rory M., Vallabhaneni, Snigdha, Chiller, Tom, Forsberg, Kaitlin, Black, Stephanie R., Pacilli, Massimo, Kong, Heidi H., Lin, Michael Y., Schoeny, Michael E., Litvintseva, Anastasia P., Segre, Julia A., Hayden, Mary K.

Volltext

Topographic diversity of fungal and bacterial communities in human skin von Findley, Keisha, Oh, Julia, Yang, Joy, Conlan, Sean, Deming, Clayton, Meyer, Jennifer A., Schoenfeld, Deborah, Nomicos, Effie, Park, Morgan, Kong, Heidi H., Segre, Julia A.

Volltext

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus von Liao, Hua-Xin, Lynch, Rebecca, Zhou, Tongqing, Gao, Feng, Alam, S. Munir, Boyd, Scott D., Fire, Andrew Z., Roskin, Krishna M., Schramm, Chaim A., Zhang, Zhenhai, Zhu, Jiang, Shapiro, Lawrence, Mullikin, James C., Gnanakaran, S., Hraber, Peter, Wiehe, Kevin, Kelsoe, Garnett, Yang, Guang, Xia, Shi-Mao, Montefiori, David C., Parks, Robert, Lloyd, Krissey E., Scearce, Richard M., Soderberg, Kelly A., Cohen, Myron, Kamanga, Gift, Louder, Mark K., Tran, Lillian M., Chen, Yue, Cai, Fangping, Chen, Sheri, Moquin, Stephanie, Du, Xiulian, Joyce, M. Gordon, Srivatsan, Sanjay, Zhang, Baoshan, Zheng, Anqi, Shaw, George M., Hahn, Beatrice H., Kepler, Thomas B., Korber, Bette T. M., Kwong, Peter D., Mascola, John R., Haynes, Barton F.

Volltext

Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis von Kong, Heidi H, Oh, Julia, Deming, Clay, Conlan, Sean, Grice, Elizabeth A, Beatson, Melony A, Nomicos, Effie, Polley, Eric C, Komarow, Hirsh D, Murray, Patrick R, Turner, Maria L, Segre, Julia A

Volltext

Expanded skin virome in DOCK8-deficient patients von Tirosh, Osnat, Conlan, Sean, Deming, Clay, Lee-Lin, Shih-Queen, Huang, Xin, Su, Helen C., Freeman, Alexandra F., Segre, Julia A., Kong, Heidi H.

Volltext

Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes von Le Gallo, Matthieu, O'Hara, Andrea J, Rudd, Meghan L, Urick, Mary Ellen, Hansen, Nancy F, O'Neil, Nigel J, Price, Jessica C, Zhang, Suiyuan, England, Bryant M, Godwin, Andrew K, Sgroi, Dennis C, Hieter, Philip, Mullikin, James C, Merino, Maria J, Bell, Daphne W

Volltext

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope von Zhou, Tongqing, Zheng, Anqi, Baxa, Ulrich, Chuang, Gwo-Yu, Georgiev, Ivelin S., Kong, Rui, O’Dell, Sijy, Shahzad-ul-Hussan, Syed, Shen, Chen-Hsiang, Tsybovsky, Yaroslav, Bailer, Robert T., Gift, Syna K., Louder, Mark K., McKee, Krisha, Rawi, Reda, Stevenson, Catherine H., Stewart-Jones, Guillaume B.E., Taft, Justin D., Waltari, Eric, Yang, Yongping, Zhang, Baoshan, Shivatare, Sachin S., Shivatare, Vidya S., Lee, Chang-Chun D., Wu, Chung-Yi, Benjamin, Betty, Blakesley, Robert, Bouffard, Gerry, Brooks, Shelise, Coleman, Holly, Dekhtyar, Mila, Gregory, Michael, Guan, Xiaobin, Gupta, Jyoti, Han, Joel, Hargrove, April, Ho, Shiling, Legaspi, Richelle, Maduro, Quino, Masiello, Cathy, Maskeri, Baishali, McDowell, Jenny, Montemayor, Casandra, Mullikin, James, Park, Morgan, Riebow, Nancy, Schandler, Karen, Schmidt, Brian, Sison, Christina, Stantripop, Mal, Thomas, James, Thomas, Pam, Vemulapalli, Meg, Young, Alice, Mullikin, James C., Bewley, Carole A., Burton, Dennis R., Polonis, Victoria R., Shapiro, Lawrence, Wong, Chi-Huey, Mascola, John R., Kwong, Peter D., Wu, Xueling

Volltext

Genetic effects on liver chromatin accessibility identify disease regulatory variants von Currin, Kevin W., Erdos, Michael R., Narisu, Narisu, Rai, Vivek, Vadlamudi, Swarooparani, Perrin, Hannah J., Idol, Jacqueline R., Yan, Tingfen, Albanus, Ricardo D’Oliveira, Broadaway, K. Alaine, Etheridge, Amy S., Bonnycastle, Lori L., Orchard, Peter, Didion, John P., Chaudhry, Amarjit S., Barnabas, Beatrice B., Black, Sean, Bouffard, Gerard G., Brooks, Shelise Y., Coleman, Holly, Dekhtyar, Lyudmila, Han, Joel, Ho, Shi-ling, Kim, Juyun, Legaspi, Richelle, Maduro, Quino L., Masiello, Catherine A., McDowell, Jennifer C., Montemayor, Casandra, Mullikin, James C., Park, Morgan, Riebow, Nancy L., Schandler, Karen, Schmidt, Brian, Sison, Christina, Stantripop, Sirintorn, Thomas, James W., Thomas, Pamela J., Vemulapalli, Meghana, Young, Alice C., Innocenti, Federico, Schuetz, Erin G., Scott, Laura J., Parker, Stephen C.J., Collins, Francis S., Mohlke, Karen L.

Volltext

Roving methyltransferases generate a mosaic epigenetic landscape and influence evolution in Bacteroides fragilis group von Tisza, Michael J., Smith, Derek D. N., Clark, Andrew E., Youn, Jung-Ho, Khil, Pavel P., Dekker, John P.

Volltext