SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage von Jangi, Mohini, Fleet, Christina, Cullen, Patrick, Gupta, Shipra V., Mekhoubad, Shila, Chiao, Eric, Allaire, Norm, Bennett, C. Frank, Rigo, Frank, Krainer, Adrian R., Hurt, Jessica A., Carulli, John P., Staropoli, John F.

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Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7 von Hu, Shanhu, Marineau, Jason J, Rajagopal, Nisha, Hamman, Kristin B, Choi, Yoon Jong, Schmidt, Darby R, Ke, Nan, Johannessen, Liv, Bradley, Michael J, Orlando, David A, Alnemy, Sydney R, Ren, Yixuan, Ciblat, Stephane, Winter, Dana K, Kabro, Anzhelika, Sprott, Kevin T, Hodgson, J Graeme, Fritz, Christian C, Carulli, John P, di Tomaso, Emmanuelle, Olson, Eric R

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A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica von Estrada, Karol, Whelan, Christopher W., Zhao, Fengmei, Bronson, Paola, Handsaker, Robert E., Sun, Chao, Carulli, John P., Harris, Tim, Ransohoff, Richard M., McCarroll, Steven A., Day-Williams, Aaron G., Greenberg, Benjamin M., MacArthur, Daniel G.

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Sequencing and Analysis of JC Virus DNA From Natalizumab-Treated PML Patients von Reid, Carl E., Li, Huo, Sur, Gargi, Carmillo, Paul, Bushnell, Steven, Tizard, Rich, McAuliffe, Michele, Tonkin, Christopher, Simon, Kenneth, Goelz, Susan, Cinque, Paola, Gorelik, Leonid, Carulli, John P.

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JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection von Wharton, Jr, Keith A, Quigley, Catherine, Themeles, Marian, Dunstan, Robert W, Doyle, Kathryn, Cahir-McFarland, Ellen, Wei, Jing, Buko, Alex, Reid, Carl E, Sun, Chao, Carmillo, Paul, Sur, Gargi, Carulli, John P, Mansfield, Keith G, Westmoreland, Susan V, Staugaitis, Susan M, Fox, Robert J, Meier, Werner, Goelz, Susan E

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Erythroid lineage chromatin accessibility maps facilitate identification and validation of NFIX as a fetal hemoglobin repressor von Chaand, Mudit, Fiore, Chris, Johnston, Brian, D’Ippolito, Anthony, Moon, Diane H., Carulli, John P., Shearstone, Jeffrey R.

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Development of a multi-biomarker disease activity test for rheumatoid arthritis von Centola, Michael, Cavet, Guy, Shen, Yijing, Ramanujan, Saroja, Knowlton, Nicholas, Swan, Kathryn A, Turner, Mary, Sutton, Chris, Smith, Dustin R, Haney, Douglas J, Chernoff, David, Hesterberg, Lyndal K, Carulli, John P, Taylor, Peter C, Shadick, Nancy A, Weinblatt, Michael E, Curtis, Jeffrey R

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Convergent random forest predictor: Methodology for predicting drug response from genome-scale data applied to anti-TNF response von Bienkowska, Jadwiga R., Dalgin, Gul S., Batliwalla, Franak, Allaire, Normand, Roubenoff, Ronenn, Gregersen, Peter K., Carulli, John P.

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Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus von Lee, Hye-Soon, Lee, Annette T, Criswell, Lindsey A, Seldin, Michael F, Amos, Christopher I, Carulli, John P, Navarrete, Cristina, Remmers, Elaine F, Kastner, Daniel L, Plenge, Robert M, Li, Wentian, Gregersen, Peter K

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Progressive Multifocal Leukoencephalopathy (PML) Development Is Associated With Mutations in JC Virus Capsid Protein VP1 That Change Its Receptor Specificity von Gorelik, Leonid, Reid, Carl, Testa, Manuela, Brickelmaier, Margot, Bossolasco, Simona, Pazzi, Annamaria, Bestetti, Arabella, Carmillo, Paul, Wilson, Ewa, McAuliffe, Michele, Tonkin, Christopher, Carulli, John P., Lugovskoy, Alexey, Lazzarin, Adriano, Sunyaev, Shamil, Simon, Kenneth, Cinque, Paola

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STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus von Remmers, Elaine F, Plenge, Robert M, Lee, Hye-Soon, Lee, Annette T, Graham, Robert R, Hom, Geoffrey, Behrens, Timothy W, de Bakker, Paul I.W, Le, Julie M, Batliwalla, Franak, Li, Wentian, Masters, Seth L, Booty, Matthew G, Carulli, John P, Padyukov, Leonid, Alfredsson, Lars, Klareskog, Lars, Chen, Wei V, Amos, Christopher I, Criswell, Lindsey A, Seldin, Michael F, Kastner, Daniel L, Gregersen, Peter K

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TRAF1–C5 as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study von Plenge, Robert M, Seielstad, Mark, Padyukov, Leonid, Lee, Annette T, Remmers, Elaine F, Ding, Bo, Liew, Anthony, Khalili, Houman, Chandrasekaran, Alamelu, Davies, Leela R.L, Li, Wentian, Tan, Adrian K.S, Bonnard, Carine, Ong, Rick T.H, Thalamuthu, Anbupalam, Pettersson, Sven, Liu, Chunyu, Tian, Chao, Chen, Wei V, Carulli, John P, Beckman, Evan M, Altshuler, David, Alfredsson, Lars, Criswell, Lindsey A, Amos, Christopher I, Seldin, Michael F, Kastner, Daniel L, Klareskog, Lars, Gregersen, Peter K

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A genome-wide screen of gene–gene interactions for rheumatoid arthritis susceptibility von Liu, Chunyu, Ackerman, H. Hoxie, Carulli, John P.

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Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis von Liu, Chunyu, Batliwalla, Franak, Li, Wentian, Lee, Annette, Roubenoff, Ronenn, Beckman, Evan, Khalili, Houman, Damle, Aarti, Kern, Marlena, Furie, Richard, Dupuis, Josée, Plenge, Robert M, Coenen, Marieke J H, Behrens, Timothy W, Carulli, John P, Gregersen, Peter K

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Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7 von Staropoli, John F., Li, Huo, Chun, Seung J., Allaire, Norm, Cullen, Patrick, Thai, Alice, Fleet, Christina M., Hua, Yimin, Bennett, C. Frank, Krainer, Adrian R., Kerr, Doug, McCampbell, Alexander, Rigo, Frank, Carulli, John P.

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A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish von Ginns, Edward I, Egeland, Janice A, Paul, Steven M, Ott, Jurg, Pauls, David L, Keith, Tim P, Weissenbach, Jean, Fann, Cathy S.J, Falls, Kathleen M, Carulli, John P, Allen, Cleona R

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Whole Genome Sequencing Reveals a Chromosome 9p Deletion Causing DOCK8 Deficiency in an Adult Diagnosed with Hyper IgE Syndrome Who Developed Progressive Multifocal Leukoencephalop... von G. Day-Williams, Aaron, Sun, Chao, Jelcic, Ilijas, McLaughlin, Helen, Harris, Tim, Martin, Roland, Carulli, John P.

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CRIPTO3, a presumed pseudogene, is expressed in cancer von Sun, Chao, Orozco, Olivia, Olson, Dian L., Choi, Eugene, Garber, Ellen, Tizard, Rich, Szak, Suzanne, Sanicola, Michele, Carulli, John P.

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Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways von Cirulli, Elizabeth T., Lasseigne, Brittany N., Petrovski, Slavé, Sapp, Peter C., Dion, Patrick A., Leblond, Claire S., Couthouis, Julien, Lu, Yi-Fan, Wang, Quanli, Krueger, Brian J., Ren, Zhong, Keebler, Jonathan, Han, Yujun, Levy, Shawn E., Boone, Braden E., Wimbish, Jack R., Waite, Lindsay L., Jones, Angela L., Carulli, John P., Day-Williams, Aaron G., Staropoli, John F., Xin, Winnie W., Chesi, Alessandra, Raphael, Alya R., McKenna-Yasek, Diane, Cady, Janet, de Jong, J. M. B. Vianney, Kenna, Kevin P., Smith, Bradley N., Topp, Simon, Miller, Jack, Gkazi, Athina, Al-Chalabi, Ammar, van den Berg, Leonard H., Veldink, Jan, Silani, Vincenzo, Ticozzi, Nicola, Shaw, Christopher E., Baloh, Robert H., Appel, Stanley, Simpson, Ericka, Lagier-Tourenne, Clotilde, Pulst, Stefan M., Gibson, Summer, Trojanowski, John Q., Elman, Lauren, McCluskey, Leo, Grossman, Murray, Shneider, Neil A., Chung, Wendy K., Ravits, John M., Glass, Jonathan D., Sims, Katherine B., Van Deerlin, Vivianna M., Maniatis, Tom, Hayes, Sebastian D., Ordureau, Alban, Swarup, Sharan, Landers, John, Baas, Frank, Allen, Andrew S., Bedlack, Richard S., Harper, J. Wade, Gitler, Aaron D., Rouleau, Guy A., Brown, Robert, Harms, Matthew B., Cooper, Gregory M., Harris, Tim, Myers, Richard M., Goldstein, David B.

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Experimental comparison and cross-validation of Affymetrix HT plate and cartridge array gene expression platforms von Allaire, Normand E., Rieder, Leila E., Bienkowska, Jadwiga, Carulli, John P.

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