Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia von Landau, Dan A., Carter, Scott L., Stojanov, Petar, McKenna, Aaron, Stevenson, Kristen, Lawrence, Michael S., Sougnez, Carrie, Stewart, Chip, Sivachenko, Andrey, Wang, Lili, Wan, Youzhong, Zhang, Wandi, Shukla, Sachet A., Vartanov, Alexander, Fernandes, Stacey M., Saksena, Gordon, Cibulskis, Kristian, Tesar, Bethany, Gabriel, Stacey, Hacohen, Nir, Meyerson, Matthew, Lander, Eric S., Neuberg, Donna, Brown, Jennifer R., Getz, Gad, Wu, Catherine J.

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Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples von Cibulskis, Kristian, Lawrence, Michael S, Carter, Scott L, Sivachenko, Andrey, Jaffe, David, Sougnez, Carrie, Gabriel, Stacey, Meyerson, Matthew, Lander, Eric S, Getz, Gad

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Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing von McFadden, David G., Papagiannakopoulos, Thales, Taylor-Weiner, Amaro, Stewart, Chip, Carter, Scott L., Cibulskis, Kristian, Bhutkar, Arjun, McKenna, Aaron, Dooley, Alison, Vernon, Amanda, Sougnez, Carrie, Malstrom, Scott, Heimann, Megan, Park, Jennifer, Chen, Frances, Farago, Anna F., Dayton, Talya, Shefler, Erica, Gabriel, Stacey, Getz, Gad, Jacks, Tyler

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Absolute quantification of somatic DNA alterations in human cancer von Carter, Scott L, Cibulskis, Kristian, Helman, Elena, McKenna, Aaron, Shen, Hui, Zack, Travis, Laird, Peter W, Onofrio, Robert C, Winckler, Wendy, Weir, Barbara A, Beroukhim, Rameen, Pellman, David, Levine, Douglas A, Lander, Eric S, Meyerson, Matthew, Getz, Gad

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Pan-cancer patterns of somatic copy number alteration von Zack, Travis I, Schumacher, Steven E, Carter, Scott L, Cherniack, Andrew D, Saksena, Gordon, Tabak, Barbara, Lawrence, Michael S, Zhang, Cheng-Zhong, Wala, Jeremiah, Mermel, Craig H, Sougnez, Carrie, Gabriel, Stacey B, Hernandez, Bryan, Shen, Hui, Laird, Peter W, Getz, Gad, Meyerson, Matthew, Beroukhim, Rameen

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Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy von Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Anderson, Kenneth C., Richardson, Paul, Krishnan, Amrita, Lonial, Sagar, Kaufman, Jonathan, Siegel, David S., Vesole, David H., Roy, Vivek, Rivera, Candido E., Rajkumar, S. Vincent, Kumar, Shaji, Fonseca, Rafael, Ahmann, Greg J., Bergsagel, P. Leif, Stewart, A. Keith, Hofmeister, Craig C., Efebera, Yvonne A., Jagannath, Sundar, Chari, Ajai, Trudel, Suzanne, Reece, Donna, Wolf, Jeffrey, Martin, Thomas, Zimmerman, Todd, Rosenbaum, Cara, Jakubowiak, Andrzej J., Lebovic, Daniel, Vij, Ravi, Stockerl-Goldstein, Keith, Getz, Gad, Golub, Todd R.

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Response and Acquired Resistance to Everolimus in Anaplastic Thyroid Cancer von Wagle, Nikhil, Grabiner, Brian C, Van Allen, Eliezer M, Amin-Mansour, Ali, Taylor-Weiner, Amaro, Rosenberg, Mara, Gray, Nathanael, Barletta, Justine A, Guo, Yanan, Swanson, Scott J, Ruan, Daniel T, Hanna, Glenn J, Haddad, Robert I, Getz, Gad, Kwiatkowski, David J, Carter, Scott L, Sabatini, David M, Jänne, Pasi A, Garraway, Levi A, Lorch, Jochen H

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Detection of Mutations in Barrett’s Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma von Stachler, Matthew D., Camarda, Nicholas D., Deitrick, Christopher, Kim, Anthony, Agoston, Agoston T., Odze, Robert D., Hornick, Jason L., Nag, Anwesha, Thorner, Aaron R., Ducar, Matthew, Noffsinger, Amy, Lash, Richard H., Redston, Mark, Carter, Scott L., Davison, Jon M., Bass, Adam J.

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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine von Van Allen, Eliezer M, Wagle, Nikhil, Stojanov, Petar, Perrin, Danielle L, Cibulskis, Kristian, Marlow, Sara, Jane-Valbuena, Judit, Friedrich, Dennis C, Kryukov, Gregory, Carter, Scott L, McKenna, Aaron, Sivachenko, Andrey, Rosenberg, Mara, Kiezun, Adam, Voet, Douglas, Lawrence, Michael, Lichtenstein, Lee T, Gentry, Jeff G, Huang, Franklin W, Fostel, Jennifer, Farlow, Deborah, Barbie, David, Gandhi, Leena, Lander, Eric S, Gray, Stacy W, Joffe, Steven, Janne, Pasi, Garber, Judy, MacConaill, Laura, Lindeman, Neal, Rollins, Barrett, Kantoff, Philip, Fisher, Sheila A, Gabriel, Stacey, Getz, Gad, Garraway, Levi A

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Paired exome analysis of Barrett's esophagus and adenocarcinoma von Stachler, Matthew D, Taylor-Weiner, Amaro, Peng, Shouyong, McKenna, Aaron, Agoston, Agoston T, Odze, Robert D, Davison, Jon M, Nason, Katie S, Loda, Massimo, Leshchiner, Ignaty, Stewart, Chip, Stojanov, Petar, Seepo, Sara, Lawrence, Michael S, Ferrer-Torres, Daysha, Lin, Jules, Chang, Andrew C, Gabriel, Stacey B, Lander, Eric S, Beer, David G, Getz, Gad, Carter, Scott L, Bass, Adam J

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A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers von Carter, Scott L, Eklund, Aron C, Kohane, Isaac S, Harris, Lyndsay N, Szallasi, Zoltan

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Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer von Kamran, Sophia C, Lennerz, Jochen K, Margolis, Claire A, Liu, David, Reardon, Brendan, Wankowicz, Stephanie A, Van Seventer, Emily E, Tracy, Adam, Wo, Jennifer Y, Carter, Scott L, Willers, Henning, Corcoran, Ryan B, Hong, Theodore S, Van Allen, Eliezer M

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The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA -Mutant Breast Cancer Brain Metastases von Ippen, Franziska M, Alvarez-Breckenridge, Christopher A, Kuter, Benjamin M, Fink, Alexandria L, Bihun, Ivanna V, Lastrapes, Matthew, Penson, Tristan, Schmidt, Stephen P, Wojtkiewicz, Gregory R, Ning, Jianfang, Subramanian, Megha, Giobbie-Hurder, Anita, Martinez-Lage, Maria, Carter, Scott L, Cahill, Daniel P, Wakimoto, Hiroaki, Brastianos, Priscilla K

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Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer von Liu, David, Abbosh, Philip, Keliher, Daniel, Reardon, Brendan, Miao, Diana, Mouw, Kent, Weiner-Taylor, Amaro, Wankowicz, Stephanie, Han, Garam, Teo, Min Yuen, Cipolla, Catharine, Kim, Jaegil, Iyer, Gopa, Al-Ahmadie, Hikmat, Dulaimi, Essel, Chen, David Y. T., Alpaugh, R. Katherine, Hoffman-Censits, Jean, Garraway, Levi A., Getz, Gad, Carter, Scott L., Bellmunt, Joaquim, Plimack, Elizabeth R., Rosenberg, Jonathan E., Van Allen, Eliezer M.

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The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis von Gibson, William J, Hoivik, Erling A, Halle, Mari K, Taylor-Weiner, Amaro, Cherniack, Andrew D, Berg, Anna, Holst, Frederik, Zack, Travis I, Werner, Henrica M J, Staby, Kjersti M, Rosenberg, Mara, Stefansson, Ingunn M, Kusonmano, Kanthida, Chevalier, Aaron, Mauland, Karen K, Trovik, Jone, Krakstad, Camilla, Giannakis, Marios, Hodis, Eran, Woie, Kathrine, Bjorge, Line, Vintermyr, Olav K, Wala, Jeremiah A, Lawrence, Michael S, Getz, Gad, Carter, Scott L, Beroukhim, Rameen, Salvesen, Helga B

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Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade von Gstalder, Cécile, Liu, David, Miao, Diana, Lutterbach, Bart, DeVine, Alexander L, Lin, Chenyu, Shettigar, Megha, Pancholi, Priya, Buchbinder, Elizabeth I, Carter, Scott L, Manos, Michael P, Rojas-Rudilla, Vanesa, Brennick, Ryan, Gjini, Evisa, Chen, Pei-Hsuan, Lako, Ana, Rodig, Scott, Yoon, Charles H, Freeman, Gordon J, Barbie, David A, Hodi, F Stephen, Miles, Wayne, Van Allen, Eliezer M, Haq, Rizwan

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Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis von Brastianos, Priscilla K., Strickland, Matthew R., Lee, Eudocia Quant, Wang, Nancy, Cohen, Justine V., Chukwueke, Ugonma, Forst, Deborah Anne, Eichler, April, Overmoyer, Beth, Lin, Nancy U., Chen, Wendy Y., Bardia, Aditya, Juric, Dejan, Dagogo-Jack, Ibiayi, White, Michael D., Dietrich, Jorg, Nayyar, Naema, Kim, Albert E., Alvarez-Breckenridge, Christopher, Mahar, Maura, Mora, Joana L., Nahed, Brian V., Jones, Pamela S., Shih, Helen A., Gerstner, Elizabeth R., Giobbie-Hurder, Anita, Carter, Scott L., Oh, Kevin, Cahill, Daniel P., Sullivan, Ryan J.

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Systematic genomic and translational efficiency studies of uveal melanoma von Johnson, Chelsea Place, Kim, Ivana K, Esmaeli, Bita, Amin-Mansour, Ali, Treacy, Daniel J, Carter, Scott L, Hodis, Eran, Wagle, Nikhil, Seepo, Sara, Yu, Xiaoxing, Lane, Anne Marie, Gragoudas, Evangelos S, Vazquez, Francisca, Nickerson, Elizabeth, Cibulskis, Kristian, McKenna, Aaron, Gabriel, Stacey B, Getz, Gad, Van Allen, Eliezer M, 't Hoen, Peter A C, Garraway, Levi A, Woodman, Scott E

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Gene co-expression network topology provides a framework for molecular characterization of cellular state von Carter, Scott L., Brechbühler, Christian M., Griffin, Michael, Bond, Andrew T.

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Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma von George, Suzanne, Miao, Diana, Demetri, George D., Adeegbe, Dennis, Rodig, Scott J., Shukla, Sachet, Lipschitz, Mikel, Amin-Mansour, Ali, Raut, Chandrajit P., Carter, Scott L., Hammerman, Peter, Freeman, Gordon J., Wu, Catherine J., Ott, Patrick A., Wong, Kwok-Kin, Van Allen, Eliezer M.

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