Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia： Yin and Yang von Zhou, Hong-Sheng, Carter, Bing Z, Andreeff, Michael

Volltext

Menin inhibition decreases Bcl-2 and synergizes with venetoclax in NPM1/FLT3-mutated AML von Carter, Bing Z., Tao, Wenjing, Mak, Po Yee, Ostermann, Lauren B., Mak, Duncan, McGeehan, Gerard, Ordentlich, Peter, Andreeff, Michael

Volltext

SMAC mimetics as potential cancer therapeutics in myeloid malignancies von Boddu, Prajwal, Carter, Bing Z., Verstovsek, Srdan, Pemmaraju, Naveen

Volltext

EXABS-147-AML How Do We Overcome Resistance to Venetoclax von Saxena, Kapil, Carter, Bing Z, Konopleva, Marina

Volltext

An ARC-Regulated IL1β/Cox-2/PGE2/β-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML von Carter, Bing Z, Mak, Po Yee, Wang, Xiangmeng, Tao, Wenjing, Ruvolo, Vivian, Mak, Duncan, Mu, Hong, Burks, Jared K, Andreeff, Michael

Volltext

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia von Ebner, Jessica, Schmoellerl, Johannes, Piontek, Martin, Manhart, Gabriele, Troester, Selina, Carter, Bing Z., Neubauer, Heidi, Moriggl, Richard, Szakács, Gergely, Zuber, Johannes, Köcher, Thomas, Andreeff, Michael, Sperr, Wolfgang R., Valent, Peter, Grebien, Florian

Volltext

Inhibition of menin, BCL-2, and FLT3 combined with a hypomethylating agent cures NPM1/FLT3 -ITD/-TKD mutant acute myeloid leukemia in a patient-derived xenograft model von Carter, Bing Z, Mak, Po Yee, Tao, Wenjing, Ostermann, Lauren B, Mak, Duncan H, Ke, Baozhen, Ordentlich, Peter, McGeehan, Gerard M, Andreeff, Michael

Volltext

Molecular Mechanisms of Ferroptosis and Updates of Ferroptosis Studies in Cancers and Leukemia von Akiyama, Hiroki, Carter, Bing Z, Andreeff, Michael, Ishizawa, Jo

Volltext

Beyond BCL-2 Inhibition in Acute Myloid Leukemia: Other Approaches to Leverage the Apoptotic Pathway von Maiti, Abhishek, Carter, Bing Z., Andreeff, Michael, Konopleva, Marina Y.

Volltext

Bcl-2 inhibition combined with PPARα activation synergistically targets leukemic stem cell-like cells in acute myeloid leukemia von Xie, Chendi, Zhou, Hui, Qin, Dongmei, Zheng, Huijian, Tang, Yuanfang, Li, Wenjuan, Zhou, Jie, Liu, Long, Yu, Xinxin, Duan, Hongpeng, Zhou, Yong, Li, Zhifeng, Fang, Zhihong, Luo, Yiming, Carter, Bing Z., Xu, Bing, Zha, Jie

Volltext

Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3 -Mutant Acute Myeloid Leukemia von Jiang, Xuejie, Mak, Po Yee, Mu, Hong, Tao, Wenjing, Mak, Duncan H, Kornblau, Steven, Zhang, Qi, Ruvolo, Peter, Burks, Jared K, Zhang, Weiguo, McQueen, Teresa, Pan, Rongqing, Zhou, Hongsheng, Konopleva, Marina, Cortes, Jorge, Liu, Qifa, Andreeff, Michael, Carter, Bing Z

Volltext

AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3 -ITD acute myeloid leukemia von Post, Sean M, Ma, Huaxian, Malaney, Prerna, Zhang, Xiaorui, Aitken, Marisa J L, Mak, Po Yee, Ruvolo, Vivian R, Yasuhiro, Tomoko, Kozaki, Ryohei, Chan, Lauren E, Ostermann, Lauren B, Konopleva, Marina, Carter, Bing Z, DiNardo, Courtney, Andreeff, Michael D, Khoury, Joseph D, Ruvolo, Peter P

Volltext

Combined inhibition of MDM2 and BCR-ABL1 tyrosine kinase targets chronic myeloid leukemia stem/progenitor cells in a murine model von Carter, Bing Z., Mak, Po Yee, Mu, Hong, Wang, Xiangmeng, Tao, Wenjing, Mak, Duncan H., Dettman, Elisha J., Cardone, Michael, Zernovak, Oleg, Seki, Takahiko, Andreeff, Michael

Volltext

Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia von Wang, Xiangmeng, Mak, Po Yee, Mu, Hong, Tao, Wenjing, Rao, Arvind, Visweswaran, Ravikumar, Ruvolo, Vivian, Pachter, Jonathan A., Weaver, David T., Andreeff, Michael, Xu, Bing, Carter, Bing Z.

Volltext

Mitochondrial regulation of GPX4 inhibition–mediated ferroptosis in acute myeloid leukemia von Akiyama, Hiroki, Zhao, Ran, Ostermann, Lauren B., Li, Ziyi, Tcheng, Matthew, Yazdani, Samar J., Moayed, Arman, Pryor, Malcolm L., Slngh, Sandeep, Baran, Natalia, Ayoub, Edward, Nishida, Yuki, Mak, Po Yee, Ruvolo, Vivian R., Carter, Bing Z., Schimmer, Aaron D., Andreeff, Michael, Ishizawa, Jo

Volltext

A novel HDAC inhibitor chidamide combined with imatinib synergistically targets tyrosine kinase inhibitor resistant chronic myeloid leukemia cells von He, Bailin, Wang, Qiang, Liu, Xiaoli, Lu, Ziyuan, Han, Jiaochan, Pan, Chengyun, Carter, Bing Z., Liu, Qifa, Xu, Na, Zhou, Hongsheng

Volltext

Combination of dasatinib and venetoclax in newly diagnosed chronic phase chronic myeloid leukemia von Jabbour, Elias, Haddad, Fadi G., Sasaki, Koji, Carter, Bing Z., Alvarado, Yesid, Nasnas, Cedric, Nasr, Lewis, Masarova, Lucia, Daver, Naval, Pemmaraju, Naveen, Short, Nicholas J., Skinner, Jeffrey, Kadia, Tapan, Borthakur, Gautam, Garcia‐Manero, Guillermo, Ravandi, Farhad, Issa, Ghayas C., Andreeff, Michael, Kantarjian, Hagop

Volltext

miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathways von Fang, Zhi Hong, Wang, Si Li, Zhao, Jin Tao, Lin, Zhi Juan, Chen, Lin Yan, Su, Rui, Xie, Si Ting, Carter, Bing Z, Xu, Bing

Volltext

Impact of FLT3-ITD allele ratio and ITD length on therapeutic outcome in cytogenetically normal AML patients without NPM1 mutation von Chen, Fang, Sun, Junya, Yin, Changxin, Cheng, Jiaying, Ni, Jinle, Jiang, Ling, Wang, Qiang, Yu, Guopan, Wei, Yongqiang, Liu, Xiaoli, Sun, Jing, Carter, Bing Z., Jiang, Xuejie

Volltext

Application of machine learning methods in clinical trials for precision medicine von Wang, Yizhuo, Carter, Bing Z, Li, Ziyi, Huang, Xuelin

Volltext