A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling von Athuluri-Divakar, Sai Krishna, Vasquez-Del Carpio, Rodrigo, Dutta, Kaushik, Baker, Stacey J., Cosenza, Stephen C., Basu, Indranil, Gupta, Yogesh K., Reddy, M.V. Ramana, Ueno, Lynn, Hart, Jonathan R., Vogt, Peter K., Mulholland, David, Guha, Chandan, Aggarwal, Aneel K., Reddy, E. Premkumar

Volltext

Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma von Wang, Zhiqiang, Da Silva, Thiago G, Jin, Ke, Han, Xiaoqing, Ranganathan, Prathibha, Zhu, Xiaoxia, Sanchez-Mejias, Avencia, Bai, Feng, Li, Bin, Fei, Dennis Liang, Weaver, Kelly, Carpio, Rodrigo Vasquez-Del, Moscowitz, Anna E, Koshenkov, Vadim P, Sanchez, Lilly, Sparling, Lynne, Pei, Xin-Hai, Franceschi, Dido, Ribeiro, Afonso, Robbins, David J, Livingstone, Alan S, Capobianco, Anthony J

Volltext

Mechanism for Coordinated RNA Packaging and Genome Replication by Rotavirus Polymerase VP1 von Lu, Xiaohui, McDonald, Sarah M., Tortorici, M. Alejandra, Tao, Yizhi Jane, Vasquez-Del Carpio, Rodrigo, Nibert, Max L., Patton, John T., Harrison, Stephen C.

Volltext

Influence of the Rustic Bamboo Envelope Construction Technique on the Thermal Performance of Vernacular Housing in the Ecuadorian Coastal Region: The Case of El Carmen-Manabí von Carpio, Rodrigo, Valarezo, Fernanda, Aguirre-Maldonado, Eduardo, Balcázar-Arciniega, Cristian

Volltext

Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression von Chen, Xu-Qiao, Barrero, Carlos A, Vasquez-Del Carpio, Rodrigo, Reddy, E Premkumar, Fecchio, Chiara, Merali, Salim, Deglincerti, Alessia, Fang, Cheng, Rogers, Jack, Maccecchini, Maria L

Volltext

NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis von WEAVER, Kelly L, ALVES-GUERRA, Marie-Clotilde, DEMAREST, Renee M, TZIMAS, Cristos, RICE, Meghan, CARPIO, Rodrigo Vasquez-Del, DAHMANE, Nadia, ROBBINS, David J, CAPOBIANCO, Anthony J, KE JIN, ZHIQIANG WANG, XIAOQING HAN, RANGANATHAN, Prathibha, XIAOXIA ZHU, DASILVA, Thiago, WEI LIU, RATTI, Francesca

Volltext

Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity von Kumar, Mukesh, Jayaram, Hariharan, Vasquez-Del Carpio, Rodrigo, Jiang, Xiaofang, Taraporewala, Zenobia F, Jacobson, Raymond H, Patton, John T, Prasad, B V Venkataram

Volltext

Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion von Vasquez-Del Carpio, Rodrigo, Silverstein, Timothy D, Lone, Samer, Swan, Michael K, Choudhury, Jayati R, Johnson, Robert E, Prakash, Satya, Prakash, Louise, Aggarwal, Aneel K

Volltext

Histidine Triad-like Motif of the Rotavirus NSP2 Octamer Mediates both RTPase and NTPase Activities von Vasquez-Del Carpio, Rodrigo, Gonzalez-Nilo, Fernando D., Riadi, Gonzalo, Taraporewala, Zenobia F., Patton, John T.

Volltext

Role of Human DNA Polymerase κ in Extension Opposite from a cis–syn Thymine Dimer von Vasquez-Del Carpio, Rodrigo, Silverstein, Timothy D., Lone, Samer, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.

Volltext

Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2) von Reddy, M.V. Ramana, Akula, Balireddy, Jatiani, Shashidhar, Vasquez-Del Carpio, Rodrigo, Billa, Vinay K., Mallireddigari, Muralidhar R., Cosenza, Stephen C., Venkata Subbaiah, D.R.C., Bharathi, E. Vijaya, Pallela, Venkat R., Ramkumar, Poornima, Jain, Rinku, Aggarwal, Aneel K., Reddy, E. Premkumar

Volltext

Role of the Histidine Triad-like Motif in Nucleotide Hydrolysis by the Rotavirus RNA-packaging Protein NSP2 von Carpio, Rodrigo Vasquez-Del, González-Nilo, Fernando D., Jayaram, Hariharan, Spencer, Eugenio, Prasad, B.V. Venkataram, Patton, John T., Taraporewala, Zenobia F.

Volltext

Assembly of a Notch Transcriptional Activation Complex Requires Multimerization von Vasquez-Del Carpio, Rodrigo, Kaplan, Fred M, Weaver, Kelly L, VanWye, Jeffrey D, Alves-Guerra, Marie-Clotilde, Robbins, David J, Capobianco, Anthony J

Volltext

Structure-Function Analysis of Rotavirus NSP2 Octamer by Using a Novel Complementation System von Taraporewala, Zenobia F, Jiang, Xiaofang, Vasquez-Del Carpio, Rodrigo, Jayaram, Hariharan, Prasad, B V Venkataram, Patton, John T

Volltext

A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent von Baker, Stacey J., Cosenza, Stephen C., Athuluri-Divakar, Saikrishna, Reddy, M.V. Ramana, Vasquez-Del Carpio, Rodrigo, Jain, Rinku, Aggarwal, Aneel K., Reddy, E. Premkumar

Volltext

Abstract 2094: Dual inhibition of FLT3 and Src pathways by ON150030, a type 1 inhibitor, as a novel strategy for relapsed and refractory AML therapy von Ghaffari, Helya, Reddy, M.V. Ramana, Cosenza, Stephen C., Carpio, Rodrigo Vasques del, Reddy, E. Premkumar

Volltext

Rotavirus Glycoprotein NSP4 Is a Modulator of Viral Transcription in the Infected Cell von SILVESTRI, Lynn S, TORTORICI, M. Alejandra, VASQUEZ-DEL CARPIO, Rodrigo, PATTON, John T

Volltext

Discovery of 8‑Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3‑d]pyrimidine-6-carbonitrile (7x) as a Potent Inhibitor of Cyclin-Dependent Kinas... von Reddy, M. V. Ramana, Akula, Balireddy, Cosenza, Stephen C, Athuluridivakar, Saikrishna, Mallireddigari, Muralidhar R, Pallela, Venkat R, Billa, Vinay K, Subbaiah, D. R. C. Venkata, Bharathi, E. Vijaya, Vasquez-Del Carpio, Rodrigo, Padgaonkar, Amol, Baker, Stacey J, Reddy, E. Premkumar

Volltext

Hierarchical Phosphorylation within the Ankyrin Repeat Domain Defines a Phosphoregulatory Loop That Regulates Notch Transcriptional Activity von Ranganathan, Prathibha, Vasquez-Del Carpio, Rodrigo, Kaplan, Fred M., Wang, Hong, Gupta, Ashu, VanWye, Jeffrey D., Capobianco, Anthony J.

Volltext

Rigosertib Blocks RAS Signaling By Acting As a Small Molecule RAS Mimetic That Binds to the RAS-Binding Domains of RAS Effector Proteins von Reddy, E. Premkumar, Divakar, Sai Krishna, Vasquez-Del Carpio, Rodrigo, Dutta, Kaushik, Baker, Stacey J, Reddy, Ramana, Aggarwal, Aneel K

Volltext