ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells von Guedan, Sonia, Chen, Xi, Madar, Aviv, Carpenito, Carmine, McGettigan, Shannon E., Frigault, Matthew J., Lee, Jihyun, Posey, Avery D., Scholler, John, Scholler, Nathalie, Bonneau, Richard, June, Carl H.

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The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade von Schaer, David A., Beckmann, Richard P., Dempsey, Jack A., Huber, Lysiane, Forest, Amelie, Amaladas, Nelusha, Li, Yanxia, Wang, Ying Cindy, Rasmussen, Erik R., Chin, Darin, Capen, Andrew, Carpenito, Carmine, Staschke, Kirk A., Chung, Linda A., Litchfield, Lacey M., Merzoug, Farhana F., Gong, Xueqian, Iversen, Philip W., Buchanan, Sean, de Dios, Alfonso, Novosiadly, Ruslan D., Kalos, Michael

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The Folate Pathway Inhibitor Pemetrexed Pleiotropically Enhances Effects of Cancer Immunotherapy von Schaer, David A, Geeganage, Sandaruwan, Amaladas, Nelusha, Lu, Zhao Hai, Rasmussen, Erik R, Sonyi, Andreas, Chin, Darin, Capen, Andrew, Li, Yanxia, Meyer, Catalina M, Jones, Bonita D, Huang, Xiaodong, Luo, Shuang, Carpenito, Carmine, Roth, Kenneth D, Nikolayev, Alexander, Tan, Bo, Brahmachary, Manisha, Chodavarapu, Krishna, Dorsey, Frank C, Manro, Jason R, Doman, Thompson N, Donoho, Gregory P, Surguladze, David, Hall, Gerald E, Kalos, Michael, Novosiadly, Ruslan D

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Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains von Carpenito, Carmine, Milone, Michael C, Hassan, Raffit, Simonet, Jacqueline C, Lakhal, Mehdi, Suhoski, Megan M, Varela-Rohena, Angel, Haines, Kathleen M, Heitjan, Daniel F, Albelda, Steven M, Carroll, Richard G, Riley, James L, Pastan, Ira, June, Carl H

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Concise Review: Guidance in Developing Commercializable Autologous/Patient‐Specific Cell Therapy Manufacturing von Eaker, Shannon, Armant, Myriam, Brandwein, Harvey, Burger, Scott, Campbell, Andrew, Carpenito, Carmine, Clarke, Dominic, Fong, Timothy, Karnieli, Ohad, Niss, Knut, Van't Hof, Wouter, Wagey, Ravenska

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Dichotomous impact of affinity on the function of T cell engaging bispecific antibodies von Poussin, Mathilde, Sereno, Arlene, Wu, Xiufeng, Huang, Flora, Manro, Jason, Cao, Shanshan, Carpenito, Carmine, Glasebrook, Andrew, Powell Jr, Daniel J, Demarest, Stephen

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Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence von Bailey, Stefanie R., Nelson, Michelle H., Majchrzak, Kinga, Bowers, Jacob S., Wyatt, Megan M., Smith, Aubrey S., Neal, Lillian R., Shirai, Keisuke, Carpenito, Carmine, June, Carl H., Zilliox, Michael J., Paulos, Chrystal M.

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Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054 von Li, Yiwen, Carpenito, Carmine, Wang, George, Surguladze, David, Forest, Amelie, Malabunga, Maria, Murphy, Mary, Zhang, Yiwei, Sonyi, Andreas, Chin, Darin, Burtrum, Douglas, Inigo, Ivan, Pennello, Anthony, Shen, Leyi, Malherbe, Laurent, Chen, Xinlei, Hall, Gerald, Haidar, Jaafar N, Ludwig, Dale L, Novosiadly, Ruslan D, Kalos, Michael

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Time-dependent cytotoxic drugs selectively cooperate with IL-18 for cancer chemo-immunotherapy von Alagkiozidis, Ioannis, Facciabene, Andrea, Tsiatas, Marinos, Carpenito, Carmine, Benencia, Fabian, Adams, Sarah, Jonak, Zdenka, June, Carl H, Powell, Jr, Daniel J, Coukos, George

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Efficient Clinical Scale Gene Modification via Zinc Finger Nuclease–Targeted Disruption of the HIV Co-receptor CCR5 von Maier, Dawn A., Brennan, Andrea L., Jiang, Shuguang, Binder-Scholl, Gwendolyn K., Lee, Gary, Plesa, Gabriela, Zheng, Zhaohui, Cotte, Julio, Carpenito, Carmine, Wood, Travis, Spratt, S. Kaye, Ando, Dale, Gregory, Philip, Holmes, Michael C., Perez, Elena. E., Riley, James L., Carroll, Richard G., June, Carl H., Levine, Bruce L.

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Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells von Carroll, Richard G, Carpenito, Carmine, Shan, Xiaochuan, Danet-Desnoyers, Gwenn, Liu, Ronghua, Jiang, Shuguang, Albelda, Steven M, Golovina, Tatiana, Coukos, George, Riley, James L, Jonak, Zdenka L, June, Carl H

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Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL-18 von Alagkiozidis, Ioannis, Facciabene, Andrea, Carpenito, Carmine, Benencia, Fabian, Jonak, Zdenka, Adams, Sarah, Carroll, Richard G, Gimotty, Phyllis A, Hammond, Rachel, Danet-Desnoyers, Gwen-äel, June, Carl H, Powell, Jr, Daniel J, Coukos, George

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Correction to: Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054 von Li, Yiwen, Carpenito, Carmine, Wang, George, Surguladze, David, Forest, Amelie, Malabunga, Maria, Murphy, Mary, Zhang, Yiwei, Sonyi, Andreas, Chin, Darin, Burtrum, Douglas, Inigo, Ivan, Pennello, Anthony, Shen, Leyi, Malherbe, Laurent, Chen, Xinlei, Hall, Gerald, Haidar, Jaafar N, Ludwig, Dale L, Novosiadly, Ruslan D, Kalos, Michael

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A human memory T cell subset with stem cell–like properties von Gattinoni, Luca, Lugli, Enrico, Ji, Yun, Pos, Zoltan, Paulos, Chrystal M, Quigley, Máire F, Almeida, Jorge R, Gostick, Emma, Yu, Zhiya, Carpenito, Carmine, Wang, Ena, Douek, Daniel C, Price, David A, June, Carl H, Marincola, Francesco M, Roederer, Mario, Restifo, Nicholas P

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Expression of a Functional CCR2 Receptor Enhances Tumor Localization and Tumor Eradication by Retargeted Human T cells Expressing a Mesothelin-Specific Chimeric Antibody Receptor von MOON, Edmund K, CARPENITO, Carmine, JING SUN, WANG, Liang-Chuan S, KAPOOR, Veena, PREDINA, Jarrod, POWELL, Daniel J, RILEY, James L, JUNE, Carl H, ALBELDA, Steven M

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Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo von Milone, Michael C., Fish, Jonathan D., Carpenito, Carmine, Carroll, Richard G., Binder, Gwendolyn K., Teachey, David, Samanta, Minu, Lakhal, Mehdi, Gloss, Brian, Danet-Desnoyers, Gwenn, Campana, Dario, Riley, James L., Grupp, Stephan A., June, Carl H.

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Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor von YANGBING ZHAO, MOON, Edmund, ALBELDA, Steven M, JUNE, Carl H, CARPENITO, Carmine, PAULOS, Chrystal M, XIAOJUN LIU, BRENNAN, Andrea L, CHEW, Anne, CARROLL, Richard G, SCHOLLER, John, LEVINE, Bruce L

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Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells von BARRETT, David M, YANGBING ZHAO, XIAOJUN LIU, SHUGUANG JIANG, CARPENITO, Carmine, KALOS, Michael, CARROLL, Richard G, JUNE, Carl H, GRUPP, Stephan A

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In Vivo Persistence, Tumor Localization, and Antitumor Activity of CAR-Engineered T Cells Is Enhanced by Costimulatory Signaling through CD137 (4-1BB) von SONG, De-Gang, QUNRUI YE, CARPENITO, Carmine, POUSSIN, Mathilde, WANG, Li-Ping, CHUNYAN JI, FIGINI, Mariangela, JUNE, Carl H, COUKOS, George, POWELL, Daniel J

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Establishment of HIV-1 resistance in CD4 + T cells by genome editing using zinc-finger nucleases von June, Carl H, Perez, Elena E, Wang, Jianbin, Miller, Jeffrey C, Jouvenot, Yann, Kim, Kenneth A, Liu, Olga, Wang, Nathaniel, Lee, Gary, Bartsevich, Victor V, Lee, Ya-Li, Guschin, Dmitry Y, Rupniewski, Igor, Waite, Adam J, Carpenito, Carmine, Carroll, Richard G, S Orange, Jordan, Urnov, Fyodor D, Rebar, Edward J, Ando, Dale, Gregory, Philip D, Riley, James L, Holmes, Michael C

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