Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer von Yarmolinsky, James, Bull, Caroline J, Vincent, Emma E, Robinson, Jamie, Walther, Axel, Smith, George Davey, Lewis, Sarah J, Relton, Caroline L, Martin, Richard M

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Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study von Fang, Si, Yarmolinsky, James, Gill, Dipender, Bull, Caroline J, Perks, Claire M, Davey Smith, George, Gaunt, Tom R, Richardson, Tom G

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Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation von Jones, Nicholas, Blagih, Julianna, Zani, Fabio, Rees, April, Hill, David G., Jenkins, Benjamin J., Bull, Caroline J., Moreira, Diana, Bantan, Azari I. M., Cronin, James G., Avancini, Daniele, Jones, Gareth W., Finlay, David K., Vousden, Karen H., Vincent, Emma E., Thornton, Catherine A.

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Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis von Murphy, Neil, Song, Mingyang, Papadimitriou, Nikos, Carreras-Torres, Robert, Langenberg, Claudia, Martin, Richard M, Tsilidis, Konstantinos K, Barroso, Inês, Chen, Ji, Frayling, Timothy M, Bull, Caroline J, Vincent, Emma E, Cotterchio, Michelle, Gruber, Stephen B, Pai, Rish K, Newcomb, Polly A, Perez-Cornago, Aurora, van Duijnhoven, Franzel J B, Van Guelpen, Bethany, Vodicka, Pavel, Wolk, Alicja, Wu, Anna H, Peters, Ulrike, Chan, Andrew T, Gunter, Marc J

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The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium von Guida, Florence, Tan, Vanessa Y, Corbin, Laura J, Smith-Byrne, Karl, Alcala, Karine, Langenberg, Claudia, Stewart, Isobel D, Butterworth, Adam S, Surendran, Praveen, Achaintre, David, Adamski, Jerzy, Amiano, Pilar, Bergmann, Manuela M, Bull, Caroline J, Dahm, Christina C, Gicquiau, Audrey, Giles, Graham G, Gunter, Marc J, Haller, Toomas, Langhammer, Arnulf, Larose, Tricia L, Ljungberg, Börje, Metspalu, Andres, Milne, Roger L, Muller, David C, Nøst, Therese H, Pettersen Sørgjerd, Elin, Prehn, Cornelia, Riboli, Elio, Rinaldi, Sabina, Rothwell, Joseph A, Scalbert, Augustin, Schmidt, Julie A, Severi, Gianluca, Sieri, Sabina, Vermeulen, Roel, Vincent, Emma E, Waldenberger, Melanie, Timpson, Nicholas J, Johansson, Mattias

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A framework for research into continental ancestry groups of the UK Biobank von Constantinescu, Andrei-Emil, Mitchell, Ruth E, Zheng, Jie, Bull, Caroline J, Timpson, Nicholas J, Amulic, Borko, Vincent, Emma E, Hughes, David A

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A phenome-wide approach to identify causal risk factors for deep vein thrombosis von Constantinescu, Andrei-Emil, Bull, Caroline J, Goudswaard, Lucy J, Zheng, Jie, Elsworth, Benjamin, Timpson, Nicholas J, Moore, Samantha F, Hers, Ingeborg, Vincent, Emma E

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Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation von Martin, Susan, Tyrrell, Jessica, Thomas, E Louise, Bown, Matthew J, Wood, Andrew R, Beaumont, Robin N, Tsoi, Lam C, Stuart, Philip E, Elder, James T, Law, Philip, Houlston, Richard, Kabrhel, Christopher, Papadimitriou, Nikos, Gunter, Marc J, Bull, Caroline J, Bell, Joshua A, Vincent, Emma E, Sattar, Naveed, Dunlop, Malcolm G, Tomlinson, Ian P M, Lindström, Sara, Bell, Jimmy D, Frayling, Timothy M, Yaghootkar, Hanieh

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A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis von Constantinescu, Andrei-Emil, Hughes, David A, Bull, Caroline J, Fleming, Kathryn, Mitchell, Ruth E, Zheng, Jie, Kar, Siddhartha, Timpson, Nicholas J, Amulic, Borko, Vincent, Emma E

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Identifying targetable metabolic dependencies across colorectal cancer progression von Legge, Danny N., Collard, Tracey J., Stanko, Ewelina, Hoskin, Ashley J., Holt, Amy K., Bull, Caroline J., Kollareddy, Madhu, Bellamy, Jake, Groves, Sarah, Ma, Eric H., Hazelwood, Emma, Qualtrough, David, Amulic, Borko, Malik, Karim, Williams, Ann C., Jones, Nicholas, Vincent, Emma E.

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Causal Inference in Cancer Epidemiology: What Is the Role of Mendelian Randomization? von Yarmolinsky, James, Wade, Kaitlin H, Richmond, Rebecca C, Langdon, Ryan J, Bull, Caroline J, Tilling, Kate M, Relton, Caroline L, Lewis, Sarah J, Davey Smith, George, Martin, Richard M

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Childhood dietary patterns and cardiovascular risk factors in adolescence: results from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort von Bull, Caroline J, Northstone, Kate

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Early Metabolic Features of Genetic Liability to Type 2 Diabetes: Cohort Study With Repeated Metabolomics Across Early Life von Bell, Joshua A, Bull, Caroline J, Gunter, Marc J, Carslake, David, Mahajan, Anubha, Davey Smith, George, Timpson, Nicholas J, Vincent, Emma E

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Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma von Riscal, Romain, Bull, Caroline J, Mesaros, Clementina, Finan, Jennifer M, Carens, Madeleine, Ho, Elaine S, Xu, Jimmy P, Godfrey, Jason, Brennan, Paul, Johansson, Mattias, Purdue, Mark P, Chanock, Stephen J, Mariosa, Daniela, Timpson, Nicholas J, Vincent, Emma E, Keith, Brian, Blair, Ian A, Skuli, Nicolas, Simon, M Celeste

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The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT) von Corbin, Laura J., Hughes, David A., Bull, Caroline J., Vincent, Emma E., Smith, Madeleine L., McConnachie, Alex, Messow, Claudia-Martina, Welsh, Paul, Taylor, Roy, Lean, Michael E. J., Sattar, Naveed, Timpson, Nicholas J.

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Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study von Constantinescu, Andrei-Emil, Bull, Caroline J, Jones, Nicholas, Mitchell, Ruth, Burrows, Kimberley, Dimou, Niki, Bézieau, Stéphane, Brenner, Hermann, Buchanan, Daniel D, D'Amato, Mauro, Jenkins, Mark A, Moreno, Victor, Pai, Rish K, Um, Caroline Y, White, Emily, Murphy, Neil, Gunter, Marc, Timpson, Nicholas J, Huyghe, Jeroen R, Vincent, Emma E

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The association between body mass index and metabolite response to a liquid mixed meal challenge: a Mendelian randomization study von Hughes, David A, Li-Gao, Ruifang, Bull, Caroline J, de Mutsert, Renée, Rosendaal, Frits R, Mook-Kanamori, Dennis O, Willems van Dijk, Ko, Timpson, Nicholas J

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Mendelian randomization applied to pharmaceutical use: the case of metformin and lung cancer von Yarmolinsky, James, Bull, Caroline J, Walker, Venexia M, Nounu, Aayah, Davey Smith, George

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Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis von Yarmolinsky, James, Bouras, Emmanouil, Constantinescu, Andrei, Burrows, Kimberley, Bull, Caroline J., Vincent, Emma E., Martin, Richard M., Dimopoulou, Olympia, Lewis, Sarah J., Moreno, Victor, Vujkovic, Marijana, Chang, Kyong-Mi, Voight, Benjamin F., Tsao, Philip S., Gunter, Marc J., Hampe, Jochen, Pellatt, Andrew J., Pharoah, Paul D. P., Schoen, Robert E., Gallinger, Steven, Jenkins, Mark A., Pai, Rish K., Gill, Dipender, Tsilidis, Kostas K.

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Distinct metabolic features of genetic liability to type 2 diabetes and coronary artery disease: a reverse Mendelian randomization study von Smith, Madeleine L., Bull, Caroline J., Holmes, Michael V., Davey Smith, George, Sanderson, Eleanor, Anderson, Emma L., Bell, Joshua A.

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