An Alzheimer’s disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons von Cukier, Holly N., Duarte, Carolina L., Laverde-Paz, Mayra J., Simon, Shaina A., Van Booven, Derek J., Miyares, Amanda T., Whitehead, Patrice L., Hamilton-Nelson, Kara L., Adams, Larry D., Carney, Regina M., Cuccaro, Michael L., Vance, Jeffery M., Pericak-Vance, Margaret A., Griswold, Anthony J., Dykxhoorn, Derek M.

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Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport von Kunkle, Brian W, Vardarajan, Badri N, Naj, Adam C, Whitehead, Patrice L, Rolati, Sophie, Slifer, Susan, Carney, Regina M, Cuccaro, Michael L, Vance, Jeffery M, Gilbert, John R, Wang, Li-San, Farrer, Lindsay A, Reitz, Christiane, Haines, Jonathan L, Beecham, Gary W, Martin, Eden R, Schellenberg, Gerard D, Mayeux, Richard P, Pericak-Vance, Margaret A

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Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians von Kohli, Martin A, John-Williams, Krista, Rajbhandary, Ruchita, Naj, Adam, Whitehead, Patrice, Hamilton, Kara, Carney, Regina M, Wright, Clinton, Crocco, Elizabeth, Gwirtzman, Harry E, Lang, Rosalyn, Beecham, Gary, Martin, Eden R, Gilbert, John, Benatar, Michael, Small, Gary W, Mash, Deborah, Byrd, Goldie, Haines, Jonathan L, Pericak-Vance, Margaret A, Züchner, Stephan

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SORL1 mutations in early- and late-onset Alzheimer disease von Cuccaro, Michael L, Carney, Regina M, Zhang, Yalun, Bohm, Christopher, Kunkle, Brian W, Vardarajan, Badri N, Whitehead, Patrice L, Cukier, Holly N, Mayeux, Richard, St George-Hyslop, Peter, Pericak-Vance, Margaret A

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Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk von Hohman, Timothy J, Cooke-Bailey, Jessica N, Reitz, Christiane, Jun, Gyungah, Naj, Adam, Beecham, Gary W, Liu, Zhi, Carney, Regina M, Vance, Jeffrey M, Cuccaro, Michael L, Rajbhandary, Ruchita, Vardarajan, Badri Narayan, Wang, Li-San, Valladares, Otto, Lin, Chiao-Feng, Larson, Eric B, Graff-Radford, Neill R, Evans, Denis, De Jager, Philip L, Crane, Paul K, Buxbaum, Joseph D, Murrell, Jill R, Raj, Towfique, Ertekin-Taner, Nilufer, Logue, Mark W, Baldwin, Clinton T, Green, Robert C, Barnes, Lisa L, Cantwell, Laura B, Fallin, M. Daniele, Go, Rodney C.P, Griffith, Patrick, Obisesan, Thomas O, Manly, Jennifer J, Lunetta, Kathryn L, Kamboh, M. Ilyas, Lopez, Oscar L, Bennett, David A, Hardy, John, Hendrie, Hugh C, Hall, Kathleen S, Goate, Alison M, Lang, Rosalyn, Byrd, Goldie S, Kukull, Walter A, Foroud, Tatiana M, Farrer, Lindsay A, Martin, Eden R, Pericak-Vance, Margaret A, Schellenberg, Gerard D, Mayeux, Richard, Haines, Jonathan L, Thornton-Wells, Tricia A

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ABCA7 frameshift deletion associated with Alzheimer disease in African Americans von Cukier, Holly N, Kunkle, Brian W, Vardarajan, Badri N, Rolati, Sophie, Hamilton-Nelson, Kara L, Kohli, Martin A, Whitehead, Patrice L, Dombroski, Beth A, Van Booven, Derek, Lang, Rosalyn, Dykxhoorn, Derek M, Farrer, Lindsay A, Cuccaro, Michael L, Vance, Jeffery M, Gilbert, John R, Beecham, Gary W, Martin, Eden R, Carney, Regina M, Mayeux, Richard, Schellenberg, Gerard D, Byrd, Goldie S, Haines, Jonathan L, Pericak-Vance, Margaret A

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Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease von Kunkle, Brian W, Jaworski, James, Barral, Sandra, Vardarajan, Badri, Beecham, Gary W, Martin, Eden R, Cantwell, Laura S, Partch, Amanda, Bird, Thomas D, Raskind, Wendy H, DeStefano, Anita L, Carney, Regina M, Cuccaro, Michael, Vance, Jeffrey M, Farrer, Lindsay A, Goate, Alison M, Foroud, Tatiana, Mayeux, Richard P, Schellenberg, Gerard D, Haines, Jonathan L, Pericak-Vance, Margaret A

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Identification of MeCP2 mutations in a series of females with autistic disorder von Carney, Regina M., Wolpert, Chantelle M., Ravan, Sarah A., Shahbazian, Mona, Ashley-Koch, Allison, Cuccaro, Michael L., Vance, Jeffery M., Pericak-Vance, Margaret A.

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Parkinsonism and distinct dementia patterns in a family with the MAPT R406W mutation von Carney, Regina M, Kohli, Martin A, Kunkle, Brian W, Naj, Adam C, Gilbert, John R, Züchner, Stephan, Pericak-Vance, Margaret A

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Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease von Kohli, Martin A, Cukier, Holly N, Hamilton-Nelson, Kara L, Rolati, Sophie, Kunkle, Brian W, Whitehead, Patrice L, Züchner, Stephan L, Farrer, Lindsay A, Martin, Eden R, Beecham, Gary W, Haines, Jonathan L, Vance, Jeffery M, Cuccaro, Michael L, Gilbert, John R, Schellenberg, Gerard D, Carney, Regina M, Pericak-Vance, Margaret A

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PATHOGENIC SORL1 MUTATIONS AND PARKINSONIAN FEATURES IN ALZHEIMER'S DISEASE von Cuccaro, Michael L, Carney, Regina M, Cukier, Holly N, Kunkle, Brian W, Vardarajan, Badri N, Bohm, Christopher, Zhang, Yalun, St George-Hyslop, Peter, Mayeux, Richard, Pericak-Vance, Margaret A

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WHOLE EXOME SEQUENCING OF LATE ONSET MULTIPLEX FAMILIES IDENTIFIES RARE CODING VARIANTS IN KNOWN AND NOVEL ALZHEIMER’S DISEASE GENES von Cukier, Holly N, Kunkle, Brian W, Rolati, Sophie, Whitehead, Patrice L, Vance, Jeffery M, Cuccaro, Michael L, Carney, Regina M, Gilbert, John R, Martin, Eden R, Beecham, Gary W, Haines, Jonathan L, Pericak-Vance, Margaret A, Hamilton-Nelson, Kara L

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IDENTIFICATION OF NOVEL CANDIDATE GENES FOR EARLY-ONSET ALZHEIMER'S DISEASE THROUGH INTEGRATED WHOLE-EXOME SEQUENCING AND EXOME CHIP ARRAY ASSOCIATION ANALYSIS von Kunkle, Brian W, Vardarajan, Badri N, Naj, Adam C, Cukier, Holly N, Dykxhoorn, Derek M, Rolati, Sophie, Whitehead, Patrice L, Carney, Regina M, Cuccaro, Michael L, Vance, Jeffery M, Genetics Consortium, Alzheimer's Disease, Farrer, Lindsay A, Haines, Jonathan L, Schellenberg, Gerard D, Martin, Eden R, Reitz, Christiane, Beecham, Gary W, Mayeux, Richard, Pericak-Vance, Margaret A

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ABCA7 FRAMESHIFT DELETION ASSOCIATED WITH ALZHEIMER’S DISEASE IN AFRICAN AMERICANS von Dykxhoorn, Derek M, Cukier, Holly N, Kunkle, Brian W, Vardarajan, Badri N, Rolati, Sophie, Hamilton-Nelson, Kara L, Kohli, Martin A, Whitehead, Patrice L, Van Booven, Derek J, Lang, Rosalyn, Farrer, Lindsay A, Cuccaro, Michael L, Vance, Jeffery M, Gilbert, John R, Beecham, Gary W, Martin, Eden R, Carney, Regina M, Mayeux, Richard, Schellenberg, Gerard D, Byrd, Goldie S, Haines, Jonathan L, Pericak-Vance, Margaret A

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ABCA7 deletion associated with Alzheimer's disease in african americans von Cukier, Holly N, Kunkle, Brian W, Rolati, Sophie, Hamilton-Nelson, Kara L, Kohli, Martin A, Dombroski, Beth A, Vardarajan, Badri N, Whitehead, Patrice L, Van Booven, Derek J, Martin, Eden R, Beecham, Gary W, Farrer, Lindsay A, Cuccaro, Michael L, Vance, Jeffery M, Mayeux, Richard, Gilbert, John R, Carney, Regina M, Byrd, Goldie S, Haines, Jonathan L, Schellenberg, Gerald D, Pericak-Vance, Margaret A, Lang, Rosalyn

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Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study von Reiman, Eric M., Arboleda-Velasquez, Joseph F., Quiroz, Yakeel T., Huentelman, Matthew J., Beach, Thomas G., Caselli, Richard J., Chen, Yinghua, Su, Yi, Myers, Amanda J., Hardy, John, Paul Vonsattel, Jean, Younkin, Steven G., Bennett, David A., De Jager, Philip L., Larson, Eric B., Crane, Paul K., Keene, C. Dirk, Kamboh, M. Ilyas, Kofler, Julia K., Duque, Linda, Gilbert, John R., Gwirtsman, Harry E., Buxbaum, Joseph D., Dickson, Dennis W., Frosch, Matthew P., Ghetti, Bernardino F., Lunetta, Kathryn L., Wang, Li-San, Hyman, Bradley T., Kukull, Walter A., Foroud, Tatiana, Haines, Jonathan L., Mayeux, Richard P., Pericak-Vance, Margaret A., Schneider, Julie A., Trojanowski, John Q., Farrer, Lindsay A., Schellenberg, Gerard D., Beecham, Gary W., Montine, Thomas J., Jun, Gyungah R.

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A statistical framework for cross-tissue transcriptome-wide association analysis von Hu, Yiming, Li, Mo, Lu, Qiongshi, Weng, Haoyi, Wang, Jiawei, Zekavat, Seyedeh M., Yu, Zhaolong, Li, Boyang, Gu, Jianlei, Muchnik, Sydney, Shi, Yu, Kunkle, Brian W., Mukherjee, Shubhabrata, Natarajan, Pradeep, Naj, Adam, Kuzma, Amanda, Zhao, Yi, Crane, Paul K., Lu, Hui, Zhao, Hongyu

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The identification of rare variants in late-onset Alzheimer’s disease using extended families von Kohli, Martin, Kunkle, Brian, Naj, Adam, Carney, Regina M, Hamilton-Nelson, Kara, Rolati, Sophie, Whitehead, Patrice L, Gilbert, John, Martin, Eden, Beecham, Gary, Wang, Li-San, Mayeux, Richard, Haines, Jonathan, Farrer, Lindsay, Schellenberg, Gerard, Zuchner, Stephan, Pericak-Vance, Margaret

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Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis von Kunkle, Brian W, Schmidt, Michael, Klein, Hans-Ulrich, Naj, Adam C, Hamilton-Nelson, Kara L, Larson, Eric B, Evans, Denis A, De Jager, Phil L, Crane, Paul K, Buxbaum, Joe D, Ertekin-Taner, Nilufer, Barnes, Lisa L, Fallin, M. Daniele, Manly, Jennifer J, Go, Rodney C. P, Obisesan, Thomas O, Kamboh, M. Ilyas, Bennett, David A, Hall, Kathleen S, Goate, Alison M, Foroud, Tatiana M, Martin, Eden R, Wang, Li-San, Byrd, Goldie S, Farrer, Lindsay A, Haines, Jonathan L, Schellenberg, Gerard D, Mayeux, Richard, Pericak-Vance, Margaret A, Reitz, Christiane, Graff-Radford, Neill R, Martinez, Izri, Ayodele, Temitope, Logue, Mark W, Cantwell, Laura B, Jean-Francois, Melissa, Kuzma, Amanda B, Adams, L.D, Vance, Jeffery M, Cuccaro, Michael L, Chung, Jaeyoon, Mez, Jesse, Lunetta, Kathryn L, Jun, Gyungah R, Lopez, Oscar L, Hendrie, Hugh C, Reiman, Eric M, Kowall, Neil W, Leverenz, James B, Small, Scott A, Levey, Allan I, Golde, Todd E, Saykin, Andrew J, Starks, Takiyah D, Albert, Marilyn S, Hyman, Bradley T, Petersen, Ronald C, Sano, Mary, Wisniewski, Thomas, Vassar, Robert, Kaye, Jeffrey A, Henderson, Victor W, DeCarli, Charles, LaFerla, Frank M, Brewer, James B, Miller, Bruce L, Swerdlow, Russell H, Van Eldik, Linda J, Paulson, Henry L, Trojanowski, John Q, Chui, Helena C, Rosenberg, Roger N, Craft, Suzanne, Grabowski, Thomas J, Asthana, Sanjay, Morris, John C, Strittmatter, Stephen M, Kukull, Walter A

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A novel Alzheimer disease locus located near the gene encoding tau protein von Jun, G, Ibrahim-Verbaas, C A, Vronskaya, M, Chung, J, Naj, A C, Kunkle, B W, Wang, L-S, Bis, J C, Bellenguez, C, Harold, D, Destefano, A L, Grenier-Boley, B, Sims, R, Smith, A V, Chouraki, V, Hamilton-Nelson, K L, Ikram, M A, Fievet, N, Martin, E R, Kamatani, Y, Valladares, O, Laza, A R, Zelenika, D, Choi, S-H, Boland, A, Becker, T, Kukull, W A, van der Lee, S J, Pasquier, F, Cruchaga, C, Beekly, D, Fitzpatrick, A L, Hanon, O, Gill, M, Gudnason, V, Campion, D, Love, S, Bennett, D A, Amin, N, Berr, C, Tsolaki, Magda, Buxbaum, J D, Lopez, O L, Deramecourt, V, Fox, N C, Cantwell, L B, Tárraga, L, Dufouil, C, Hardy, J, Crane, P K, Eiriksdottir, G, Hannequin, D, Clarke, R, Evans, D, Mosley, T H, Letenneur, L, Brayne, C, Maier, W, De Jager, P, Dartigues, J-F, Hampel, H, de Bruijn, R F A G, Tzourio, C, Pastor, P, Larson, E B, O'Donovan, M C, Montine, T J, Nalls, M A, Mead, S, Reiman, E M, Jonsson, P V, St George-Hyslop, P H, Boada, M, Passmore, P, Wendland, J R, Schmidt, R, Morgan, K, Powell, J F, Carasquillo, M, Jakobsdóttir, J, Kauwe, J S K, Rujescu, D, Nöthen, M M, Hofman, A, Jones, L, Haines, J L, Psaty, B M, Van Broeckhoven, C, Holmans, P, Launer, L J, Mayeux, R, Goate, A M, Escott-Price, V, Seshadri, S, Pericak-Vance, M A, Amouyel, P, Williams, J, van Duijn, C M, Schellenberg, G D, Farrer, L A

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