Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA von Coelho, Matthew A., de Carné Trécesson, Sophie, Rana, Sareena, Zecchin, Davide, Moore, Christopher, Molina-Arcas, Miriam, East, Philip, Spencer-Dene, Bradley, Nye, Emma, Barnouin, Karin, Snijders, Ambrosius P., Lai, Wi S., Blackshear, Perry J., Downward, Julian

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RAS oncogenic activity predicts response to chemotherapy and outcome in lung adenocarcinoma von East, Philip, Kelly, Gavin P., Biswas, Dhruva, Marani, Michela, Hancock, David C., Creasy, Todd, Sachsenmeier, Kris, Swanton, Charles, Downward, Julian, de Carné Trécesson, Sophie

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An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations von Boumelha, Jesse, de Carné Trécesson, Sophie, Law, Emily K, Romero-Clavijo, Pablo, Coelho, Matthew A, Ng, Kevin W, Mugarza, Edurne, Moore, Christopher, Rana, Sareena, Caswell, Deborah R, Murillo, Miguel, Hancock, David C, Argyris, Prokopios P, Brown, William L, Durfee, Cameron, Larson, Lindsay K, Vogel, Rachel I, Suárez-Bonnet, Alejandro, Priestnall, Simon L, East, Philip, Ross, Sarah J, Kassiotis, George, Molina-Arcas, Miriam, Swanton, Charles, Harris, Reuben, Downward, Julian

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BCL-XL directly modulates RAS signalling to favour cancer cell stemness von Carné Trécesson, Sophie de, Souazé, Frédérique, Basseville, Agnès, Bernard, Anne-Charlotte, Pécot, Jessie, Lopez, Jonathan, Bessou, Margaux, Sarosiek, Kristopher A., Letai, Anthony, Barillé-Nion, Sophie, Valo, Isabelle, Coqueret, Olivier, Guette, Catherine, Campone, Mario, Gautier, Fabien, Juin, Philippe Paul

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Combining RAS(ON) G12C-selective inhibitor with SHP2 inhibition sensitises lung tumours to immune checkpoint blockade von Anastasiou, Panayiotis, Moore, Christopher, Rana, Sareena, Tomaschko, Mona, Pillsbury, Claire E., de Castro, Andrea, Boumelha, Jesse, Mugarza, Edurne, de Carné Trécesson, Sophie, Mikolajczak, Ania, Blaj, Cristina, Goldstone, Robert, Smith, Jacqueline A. M., Quintana, Elsa, Molina-Arcas, Miriam, Downward, Julian

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Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance von Pécot, Jessie, Maillet, Laurent, Le Pen, Janic, Vuillier, Céline, Trécesson, Sophie de Carné, Fétiveau, Aurélie, Sarosiek, Kristopher A., Bock, Florian J., Braun, Frédérique, Letai, Anthony, Tait, Stephen W.G., Gautier, Fabien, Juin, Philippe P.

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Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival von Braun, Frédérique, de Carné Trécesson, Sophie, Bertin-Ciftci, Joséphine, Juin, Philippe

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The cdk5 Kinase Regulates the STAT3 Transcription Factor to Prevent DNA Damage upon Topoisomerase I Inhibition von Courapied, Sandy, Sellier, Hélène, de Carné Trécesson, Sophie, Vigneron, Arnaud, Bernard, Anne-Charlotte, Gamelin, Erick, Barré, Benjamin, Coqueret, Olivier

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Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin) von Breiman, Adrien, López Robles, María Dolores, de Carné Trécesson, Sophie, Echasserieau, Klara, Bernardeau, Karine, Drickamer, Kurt, Imberty, Anne, Barillé-Nion, Sophie, Altare, Frédéric, Le Pendu, Jacques

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Genomic–transcriptomic evolution in lung cancer and metastasis von Martínez-Ruiz, Carlos, Black, James R. M., Puttick, Clare, Hill, Mark S., Demeulemeester, Jonas, Larose Cadieux, Elizabeth, Thol, Kerstin, Jones, Thomas P., Veeriah, Selvaraju, Naceur-Lombardelli, Cristina, Toncheva, Antonia, Prymas, Paulina, Rowan, Andrew, Ward, Sophia, Cubitt, Laura, Athanasopoulou, Foteini, Pich, Oriol, Karasaki, Takahiro, Moore, David A., Salgado, Roberto, Colliver, Emma, Castignani, Carla, Dietzen, Michelle, Huebner, Ariana, Al Bakir, Maise, Tanić, Miljana, Watkins, Thomas B. K., Lim, Emilia L., Al-Rashed, Ali M., Lang, Danny, Clements, James, Cook, Daniel E., Rosenthal, Rachel, Wilson, Gareth A., Frankell, Alexander M., de Carné Trécesson, Sophie, East, Philip, Kanu, Nnennaya, Litchfield, Kevin, Birkbak, Nicolai J., Hackshaw, Allan, Beck, Stephan, Van Loo, Peter, Jamal-Hanjani, Mariam, Swanton, Charles, McGranahan, Nicholas

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Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1 von Jonchère, Barbara, Vétillard, Alexandra, Toutain, Bertrand, Lam, David, Bernard, Anne Charlotte, Henry, Cécile, De Carné Trécesson, Sophie, Gamelin, Erick, Juin, Philippe, Guette, Catherine, Coqueret, Olivier

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Escape from p21-mediated Oncogene-induced Senescence Leads to Cell Dedifferentiation and Dependence on Anti-apoptotic Bcl-xL and MCL1 Proteins von de Carné Trécesson, Sophie, Guillemin, Yannis, Bélanger, Audrey, Bernard, Anne-Charlotte, Preisser, Laurence, Ravon, Elisa, Gamelin, Erick, Juin, Philippe, Barré, Benjamin, Coqueret, Olivier

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The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance von Caswell, Deborah R., Gui, Philippe, Mayekar, Manasi K., Law, Emily K., Pich, Oriol, Bailey, Chris, Boumelha, Jesse, Kerr, D. Lucas, Blakely, Collin M., Manabe, Tadashi, Martinez-Ruiz, Carlos, Bakker, Bjorn, De Dios Palomino Villcas, Juan, I. Vokes, Natalie, Dietzen, Michelle, Angelova, Mihaela, Gini, Beatrice, Tamaki, Whitney, Allegakoen, Paul, Wu, Wei, Humpton, Timothy J., Hill, William, Tomaschko, Mona, Lu, Wei-Ting, Haderk, Franziska, Al Bakir, Maise, Nagano, Ai, Gimeno-Valiente, Francisco, de Carné Trécesson, Sophie, Vendramin, Roberto, Barbè, Vittorio, Mugabo, Miriam, Weeden, Clare E., Rowan, Andrew, McCoach, Caroline E., Almeida, Bruna, Green, Mary, Gomez, Carlos, Nanjo, Shigeki, Barbosa, Dora, Moore, Chris, Przewrocka, Joanna, Black, James R. M., Grönroos, Eva, Suarez-Bonnet, Alejandro, Priestnall, Simon L., Zverev, Caroline, Lighterness, Scott, Cormack, James, Olivas, Victor, Cech, Lauren, Andrews, Trisha, Rule, Brandon, Jiao, Yuwei, Zhang, Xinzhu, Ashford, Paul, Durfee, Cameron, Venkatesan, Subramanian, Temiz, Nuri Alpay, Tan, Lisa, Larson, Lindsay K., Argyris, Prokopios P., Brown, William L., Yu, Elizabeth A., Rotow, Julia K., Guha, Udayan, Roper, Nitin, Yu, Johnny, Vogel, Rachel I., Thomas, Nicholas J., Marra, Antonio, Selenica, Pier, Yu, Helena, Bakhoum, Samuel F., Chew, Su Kit, Reis-Filho, Jorge S., Jamal-Hanjani, Mariam, Vousden, Karen H., McGranahan, Nicholas, Van Allen, Eliezer M., Kanu, Nnennaya, Harris, Reuben S., Downward, Julian, Bivona, Trever G., Swanton, Charles

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Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells von Basseville, Agnes, Preisser, Laurence, de Carné Trécesson, Sophie, Boisdron-Celle, Michèle, Gamelin, Erick, Coqueret, Olivier, Morel, Alain

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Antibodies against endogenous retroviruses promote lung cancer immunotherapy von Ng, Kevin W, Boumelha, Jesse, Enfield, Katey S S, Almagro, Jorge, Cha, Hongui, Pich, Oriol, Karasaki, Takahiro, Moore, David A, Salgado, Roberto, Sivakumar, Monica, Young, George, Molina-Arcas, Miriam, de Carné Trécesson, Sophie, Anastasiou, Panayiotis, Fendler, Annika, Au, Lewis, Shepherd, Scott T C, Martínez-Ruiz, Carlos, Puttick, Clare, Black, James R M, Watkins, Thomas B K, Kim, Hyemin, Shim, Seohee, Faulkner, Nikhil, Attig, Jan, Veeriah, Selvaraju, Magno, Neil, Ward, Sophia, Frankell, Alexander M, Al Bakir, Maise, Boos, Laura Amanda

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BCL-X L directly modulates RAS signalling to favour cancer cell stemness von Carné Trécesson, Sophie de, Souazé, Frédérique, Basseville, Agnès, Bernard, Anne-Charlotte, Pécot, Jessie, Lopez, Jonathan, Bessou, Margaux, Sarosiek, Kristopher A, Letai, Anthony, Barillé-Nion, Sophie, Valo, Isabelle, Coqueret, Olivier, Guette, Catherine, Campone, Mario, Gautier, Fabien, Juin, Philippe Paul

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An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations von Boumelha, Jesse, de Carné Trécesson, Sophie, Law, Emily K, Romero-Clavijo, Pablo, Coelho, Matthew, Ng, Kevin, Mugarza, Edurne, Moore, Christopher, Rana, Sareena, Caswell, Deborah R, Murillo, Miguel, Hancock, David C, Argyris, Prokopios P, Brown, William L, Durfee, Cameron, Larson, Lindsay K, Vogel, Rachel I, Suarez-Bonnet, Alejandro, Priestnall, Simon L, East, Philip, Ross, Sarah J, Kassiotis, George, Molina-Arcas, Miriam, Swanton, Charles, Harris, Reuben, Downward, Julian

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The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance von Caswell, Deborah R, Gui, Philippe, Mayekar, Manasi K, Law, Emily K, Pich, Oriol, Bailey, Chris, Boumelha, Jesse, Kerr, D Lucas, Blakely, Collin M, Manabe, Tadashi, Martinez-Ruiz, Carlos, Bakker, Bjorn, De Dios Palomino Villcas, Juan, I Vokes, Natalie, Dietzen, Michelle, Angelova, Mihaela, Gini, Beatrice, Tamaki, Whitney, Allegakoen, Paul, Wu, Wei, Humpton, Timothy J, Hill, William, Tomaschko, Mona, Lu, Wei-Ting, Haderk, Franziska, Al Bakir, Maise, Nagano, Ai, Gimeno-Valiente, Francisco, de Carné Trécesson, Sophie, Vendramin, Roberto, Barbè, Vittorio, Mugabo, Miriam, Weeden, Clare E, Rowan, Andrew, McCoach, Caroline E, Almeida, Bruna, Green, Mary, Gomez, Carlos, Nanjo, Shigeki, Barbosa, Dora, Moore, Chris, Przewrocka, Joanna, Black, James RM, Grönroos, Eva, Suarez-Bonnet, Alejandro, Priestnall, Simon L, Zverev, Caroline, Lighterness, Scott, Cormack, James, Olivas, Victor, Cech, Lauren, Andrews, Trisha, Rule, Brandon, Jiao, Yuwei, Zhang, Xinzhu, Ashford, Paul, Durfee, Cameron, Venkatesan, Subramanian, Temiz, Nuri Alpay, Tan, Lisa, Larson, Lindsay K, Argyris, Prokopios P, Brown, William L, Yu, Elizabeth A, Rotow, Julia K, Guha, Udayan, Roper, Nitin, Yu, Johnny, Vogel, Rachel I, Thomas, Nicholas J, Marra, Antonio, Selenica, Pier, Yu, Helena, Bakhoum, Samuel F, Chew, Su Kit, Reis-Filho, Jorge S, Jamal-Hanjani, Mariam, Vousden, Karen H, McGranahan, Nicholas, Van Allen, Eliezer M, Kanu, Nnennaya, Harris, Reuben S, Downward, Julian, Bivona, Trever G, Swanton, Charles

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Antibodies against endogenous retroviruses promote lung cancer immunotherapy von Ng, Kevin W, Boumelha, Jesse, Enfield, Katey SS, Almagro, Jorge, Cha, Hongui, Pich, Oriol, Karasaki, Takahiro, Moore, David A, Salgado, Roberto, Sivakumar, Monica, Young, George, Molina-Arcas, Miriam, de Carné Trécesson, Sophie, Anastasiou, Panayiotis, Fendler, Annika, Au, Lewis, Shepherd, Scott TC, Martínez-Ruiz, Carlos, Puttick, Clare, Black, James RM, Watkins, Thomas BK, Kim, Hyemin, Shim, Seohee, Faulkner, Nikhil, Attig, Jan, Veeriah, Selvaraju, Magno, Neil, Ward, Sophia, Frankell, Alexander M, Al Bakir, Maise, Lim, Emilia L, Hill, Mark S, Wilson, Gareth A, Cook, Daniel E, Birkbak, Nicolai J, Behrens, Axel, Yousaf, Nadia, Popat, Sanjay, Hackshaw, Allan, TRACERx Consortium, CAPTURE Consortium, Hiley, Crispin T, Litchfield, Kevin, McGranahan, Nicholas, Jamal-Hanjani, Mariam, Larkin, James, Lee, Se-Hoon, Turajlic, Samra, Swanton, Charles, Downward, Julian, Kassiotis, George

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Genomic-transcriptomic evolution in lung cancer and metastasis von Martinez-Ruiz, Carlos, Black, James R.M, Puttick, Clare, Hill, Mark, Demeulemeester, Jonas, Cadieux, Elizabeth Larose, Thol, Kerstin, Jones, Thomas, Veeriah, Selvaraju, Naceur-Lombardelli, Cristina, Toncheva, Antonia, Prymas, Paulina, Rowan, Andrew, Ward, Sophia, Cubitt, Laura, Athanasopoulou, Foteini, Pich, Oriol, Karasaki, Takahiro, Moore, David, Salgado, Roberto, Colliver, Emma, Castignani, Carla I, Dietzen, Michelle, Huebner, Ariana, Al Bakir, Maise, Tanic, Miljana G, Watkins, Thomas B.K, Lim, Emilia, Al-Rashed, Ali, Lang, Danny, Clements, James, Cook, Daniel J, Rosenthal, Rachel, Wilson, Gareth, Frankell, Alexander G, Trecesson, Sophie de Carne, East, Philip, Kanu, Nnennaya, Litchfield, Kevin, Birkbak, Nicolai, Hackshaw, Allan, Beck, Stephan, Van Loo, Peter, Jamal-Hanjani, Mariam, Swanton, Charles, McGranahan, Nicholas

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