NCOA4-mediated ferritinophagy in macrophages is crucial to sustain erythropoiesis in mice von Nai, Antonella, Lidonnici, Maria Rosa, Federico, Giorgia, Pettinato, Mariateresa, Olivari, Violante, Carrillo, Federica, Crich, Simonetta Geninatti, Ferrari, Giuliana, Camaschella, Clara, Silvestri, Laura, Carlomagno, Francesca

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NCOA4 Deficiency Impairs Systemic Iron Homeostasis von Bellelli, Roberto, Federico, Giorgia, Matte’, Alessandro, Colecchia, David, Iolascon, Achille, Chiariello, Mario, Santoro, Massimo, De Franceschi, Lucia, Carlomagno, Francesca

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Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases von Moccia, Marialuisa, Yang, Donglin, Lakkaniga, Naga Rajiv, Frett, Brendan, McConnell, Nicholas, Zhang, Lingtian, Brescia, Annalisa, Federico, Giorgia, Zhang, Lingzhi, Salerno, Paolo, Santoro, Massimo, Li, Hong-yu, Carlomagno, Francesca

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Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology von Moccia, Marialuisa, Frett, Brendan, Zhang, Lingtian, Lakkaniga, Naga Rajiv, Briggs, David C, Chauhan, Rakhee, Brescia, Annalisa, Federico, Giorgia, Yan, Wei, Santoro, Massimo, McDonald, Neil Q, Li, Hong-yu, Carlomagno, Francesca

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Tamoxifen erythroid toxicity revealed by studying the role of nuclear receptor co-activator 4 in erythropoiesis von Nai, Antonella, Pettinato, Mariateresa, Federico, Giorgia, Olivari, Violante, Carlomagno, Francesca, Silvestri, Laura

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Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition von Sottile, Rosa, Federico, Giorgia, Garofalo, Cinzia, Tallerico, Rossana, Faniello, Maria Concetta, Quaresima, Barbara, Cristiani, Costanza Maria, Di Sanzo, Maddalena, Cuda, Gianni, Ventura, Valeria, Wagner, Arnika Kathleen, Contrò, Gianluca, Perrotti, Nicola, Gulletta, Elio, Ferrone, Soldano, Kärre, Klas, Costanzo, Francesco Saverio, Carlomagno, Francesca, Carbone, Ennio

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Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology von Frett, Brendan, Carlomagno, Francesca, Moccia, Maria Luisa, Brescia, Annalisa, Federico, Giorgia, De Falco, Valentina, Admire, Brittany, Chen, Zhongzhu, Qi, Wenqing, Santoro, Massimo, Li, Hong-yu

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NCOA4 Transcriptional Coactivator Inhibits Activation of DNA Replication Origins von Bellelli, Roberto, Castellone, Maria Domenica, Guida, Teresa, Limongello, Roberto, Dathan, Nina Alayne, Merolla, Francesco, Cirafici, Anna Maria, Affuso, Andrea, Masai, Hisao, Costanzo, Vincenzo, Grieco, Domenico, Fusco, Alfredo, Santoro, Massimo, Carlomagno, Francesca

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Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors von CARLOMAGNO, Francesca, GUIDA, Teresa, ANAGANTI, Suresh, VECCHIO, Giancarlo, FUSCO, Alfredo, RYAN, Anderson J, BILLAUD, Marc, SANTORO, Massimo

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Antitumor Effects of ZD6474, a Small Molecule Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, with Additional Activity against Epidermal Growth Factor Recept... von CIARDIELLO, Fortunato, CAPUTO, Rosa, TORTORA, Giampaolo, DAMIANO, Vincenzo, CAPUTO, Roberta, TROIANI, Teresa, VITAGLIANO, Donatella, CARLOMAGNO, Francesca, VENEZIANI, Bianca Maria, FONTANINI, Gabriella, BIANCO, A. Raffaele

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BRAF Is a Therapeutic Target in Aggressive Thyroid Carcinoma von SALVATORE, Giuliana, DE FALCO, Valentina, SALERNO, Paolo, NAPPI, Tito Claudio, PEPE, Stefano, TRONCONE, Giancarlo, CARLOMAGNO, Francesca, MELILLO, Rosa Marina, WILHELM, Scott M, SANTORO, Massimo

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Ferritinophagy and Cell Cycle Control von Carlomagno, Francesca

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Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase von Moccia, Marialuisa, Liu, Qingsong, Guida, Teresa, Federico, Giorgia, Brescia, Annalisa, Zhao, Zheng, Choi, Hwan Geun, Deng, Xianming, Tan, Li, Wang, Jinhua, Billaud, Marc, Gray, Nathanael S, Carlomagno, Francesca, Santoro, Massimo

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The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells von Vitagliano, Donata, De Falco, Valentina, Tamburrino, Anna, Coluzzi, Sabrina, Troncone, Giancarlo, Chiappetta, Gennaro, Ciardiello, Fortunato, Tortora, Giampaolo, Fagin, James A, Ryan, Anderson J, Carlomagno, Francesca, Santoro, Massimo

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Identification of Polo-like Kinase 1 as a Potential Therapeutic Target in Anaplastic Thyroid Carcinoma von CLAUDIO NAPPI, Tito, SALERNO, Paolo, ZITZELSBERGER, Horst, CARLOMAGNO, Francesca, SALVATORE, Giuliana, SANTORO, Massimo

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Sorafenib Inhibits Imatinib-Resistant KIT and Platelet-Derived Growth Factor Receptor β Gatekeeper Mutants von GUIDA, Teresa, ANAGANTI, Suresh, PROVITERA, Livia, GEDRICH, Richard, SULLIVAN, Elizabeth, WILHELM, Scott M, SANTORO, Massimo, CARLOMAGNO, Francesca

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Functional expression of the CXCR4 chemokine receptor is induced by RET PTC oncogenes and is a common event in human papillary thyroid carcinomas von CASTELLONE, Maria D, GUARINO, Valentina, FUSCO, Alfredo, SANTORO, Massimo, MELILLO, Rosa Marina, DE FALCO, Valentina, CARLOMAGNO, Francesca, BASOLO, Fulvio, FAVIANA, Pinuccia, KRUHOFFER, Mogens, ORNTOFT, Torben, RUSSELL, John P, ROTHSTEIN, Jay L

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Structure prediction and validation of the ERK8 kinase domain von Strambi, Angela, Mori, Mattia, Rossi, Matteo, Colecchia, David, Manetti, Fabrizio, Carlomagno, Francesca, Botta, Maurizio, Chiariello, Mario

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Molecular Mechanisms of RET Activation in Human Cancer von SANTORO, MASSIMO, MELILLO, ROSA MARINA, CARLOMAGNO, FRANCESCA, FUSCO, ALFREDO, VECCHIO, GIANCARLO

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Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies von Bossi, Daniela, Carlomagno, Francesca, Pallavicini, Isabella, Pruneri, Giancarlo, Trubia, Maurizio, Raviele, Paola Rafaniello, Marinelli, Alessandra, Anaganti, Suresh, Cox, Maria Christina, Viale, Giuseppe, Santoro, Massimo, Di Fiore, Pier Paolo, Minucci, Saverio

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