Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals von Grifoni, Alba, Weiskopf, Daniela, Ramirez, Sydney I., Mateus, Jose, Dan, Jennifer M., Moderbacher, Carolyn Rydyznski, Rawlings, Stephen A., Sutherland, Aaron, Premkumar, Lakshmanane, Jadi, Ramesh S., Marrama, Daniel, de Silva, Aravinda M., Frazier, April, Carlin, Aaron F., Greenbaum, Jason A., Peters, Bjoern, Krammer, Florian, Smith, Davey M., Crotty, Shane, Sette, Alessandro

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Cholesterol 25‐Hydroxylase inhibits SARS‐CoV‐2 and other coronaviruses by depleting membrane cholesterol von Wang, Shaobo, Li, Wanyu, Hui, Hui, Tiwari, Shashi Kant, Zhang, Qiong, Croker, Ben A, Rawlings, Stephen, Smith, Davey, Carlin, Aaron F, Rana, Tariq M

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A human three-dimensional neural-perivascular ‘assembloid’ promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology von Wang, Lu, Sievert, David, Clark, Alex E., Lee, Sangmoon, Federman, Hannah, Gastfriend, Benjamin D., Shusta, Eric V., Palecek, Sean P., Carlin, Aaron F., Gleeson, Joseph G.

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Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids von Tiwari, Shashi Kant, Wang, Shaobo, Smith, Davey, Carlin, Aaron F., Rana, Tariq M.

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Human microglial models to study host–virus interactions von McMillan, Rachel E., Wang, Ellen, Carlin, Aaron F., Coufal, Nicole G.

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Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity von Park, Sang Ho, Siddiqi, Haley, Castro, Daniela V., De Angelis, Anna A., Oom, Aaron L., Stoneham, Charlotte A., Lewinski, Mary K., Clark, Alex E., Croker, Ben A., Carlin, Aaron F., Guatelli, John, Opella, Stanley J.

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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2 von Clausen, Thomas Mandel, Sandoval, Daniel R., Spliid, Charlotte B., Pihl, Jessica, Perrett, Hailee R., Painter, Chelsea D., Narayanan, Anoop, Majowicz, Sydney A., Kwong, Elizabeth M., McVicar, Rachael N., Thacker, Bryan E., Glass, Charles A., Yang, Zhang, Torres, Jonathan L., Golden, Gregory J., Bartels, Phillip L., Porell, Ryan N., Garretson, Aaron F., Laubach, Logan, Feldman, Jared, Yin, Xin, Pu, Yuan, Hauser, Blake M., Caradonna, Timothy M., Kellman, Benjamin P., Martino, Cameron, Gordts, Philip L.S.M., Chanda, Sumit K., Schmidt, Aaron G., Godula, Kamil, Leibel, Sandra L., Jose, Joyce, Corbett, Kevin D., Ward, Andrew B., Carlin, Aaron F., Esko, Jeffrey D.

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SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism von Oishi, Yumiko, Spann, Nathanael J., Link, Verena M., Muse, Evan D., Strid, Tobias, Edillor, Chantle, Kolar, Matthew J., Matsuzaka, Takashi, Hayakawa, Sumio, Tao, Jenhan, Kaikkonen, Minna U., Carlin, Aaron F., Lam, Michael T., Manabe, Ichiro, Shimano, Hitoshi, Saghatelian, Alan, Glass, Christopher K.

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METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection von Li, Na, Hui, Hui, Bray, Bill, Gonzalez, Gwendolyn Michelle, Zeller, Mark, Anderson, Kristian G., Knight, Rob, Smith, Davey, Wang, Yinsheng, Carlin, Aaron F., Rana, Tariq M.

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Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors von Mor, Michael, Werbner, Michal, Alter, Joel, Safra, Modi, Chomsky, Elad, Lee, Jamie C., Hada-Neeman, Smadar, Polonsky, Ksenia, Nowell, Cameron J., Clark, Alex E., Roitburd-Berman, Anna, Ben-Shalom, Noam, Navon, Michal, Rafael, Dor, Sharim, Hila, Kiner, Evgeny, Griffis, Eric R., Gershoni, Jonathan M., Kobiler, Oren, Leibel, Sandra Lawrynowicz, Zimhony, Oren, Carlin, Aaron F., Yaari, Gur, Dessau, Moshe, Gal-Tanamy, Meital, Hagin, David, Croker, Ben A., Freund, Natalia T.

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Discovery and Mechanism of SARS-CoV‑2 Main Protease Inhibitors von Huff, Sarah, Kummetha, Indrasena Reddy, Tiwari, Shashi Kant, Huante, Matthew B, Clark, Alex E, Wang, Shaobo, Bray, William, Smith, Davey, Carlin, Aaron F, Endsley, Mark, Rana, Tariq M

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Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response von Carlin, Aaron F., Uchiyama, Satoshi, Chang, Yung-Chi, Lewis, Amanda L., Nizet, Victor, Varki, Ajit

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Virologic and Immunologic Characterization of Coronavirus Disease 2019 Recrudescence After Nirmatrelvir/Ritonavir Treatment von Carlin, Aaron F, Clark, Alex E, Chaillon, Antoine, Garretson, Aaron F, Bray, William, Porrachia, Magali, Santos, AsherLev T, Rana, Tariq M, Smith, Davey M

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Hitting the diagnostic sweet spot: Point-of-care SARS-CoV-2 salivary antigen testing with an off-the-shelf glucometer von Singh, Naveen K., Ray, Partha, Carlin, Aaron F., Magallanes, Celestine, Morgan, Sydney C., Laurent, Louise C., Aronoff-Spencer, Eliah S., Hall, Drew A.

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A Dual‐Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain‐like Proteases of SARS‐CoV‐2‐Infected Cells for Accurate Detection and Rapid Inhibitor Screening... von Cheng, Yong, Borum, Raina M., Clark, Alex E., Jin, Zhicheng, Moore, Colman, Fajtová, Pavla, O'Donoghue, Anthony J., Carlin, Aaron F., Jokerst, Jesse V.

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Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus von Ali, Syed Raza, Fong, Jerry J, Carlin, Aaron F, Busch, Tamara D, Linden, Rebecka, Angata, Takashi, Areschoug, Thomas, Parast, Mana, Varki, Nissi, Murray, Jeffrey, Nizet, Victor, Varki, Ajit

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Structure-selected RBM immunogens prime polyclonal memory responses that neutralize SARS-CoV-2 variants of concern von Almanza, Gonzalo, Clark, Alex E, Kouznetsova, Valentina, Olmedillas, Eduardo, Castro, Andrea, Tsigelny, Igor F, Wu, Yan, Gao, George F, Leibel, Sandra L, Bray, William, Ollmann Saphire, Erica, Carlin, Aaron F, Zanetti, Maurizio

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SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus von Branche, Emilie, Wang, Ying-Ting, Viramontes, Karla M., Valls Cuevas, Joan M., Xie, Jialei, Ana-Sosa-Batiz, Fernanda, Shafee, Norazizah, Duttke, Sascha H., McMillan, Rachel E., Clark, Alex E., Nguyen, Michael N., Garretson, Aaron F., Crames, Jan J., Spann, Nathan J., Zhu, Zhe, Rich, Jeremy N., Spector, Deborah H., Benner, Christopher, Shresta, Sujan, Carlin, Aaron F.

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Interleukin-8 Receptor 2 (IL-8R2)-Deficient Mice Are More Resistant to Pulmonary Coccidioidomycosis than Control Mice von Carlin, Aaron F., Viriyakosol, Suganya, Okamoto, Sharon, Walls, Lorraine, Fierer, Joshua

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Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs von Schooley, Robert T., Carlin, Aaron F., Beadle, James R., Valiaeva, Nadejda, Zhang, Xing-Quan, Clark, Alex E., McMillan, Rachel E., Leibel, Sandra L., McVicar, Rachael N., Xie, Jialei, Garretson, Aaron F., Smith, Victoria, Murphy, Joyce, Hostetler, Karl Y.

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