Population Pharmacokinetics of Selumetinib and Its Metabolite N‐desmethyl‐selumetinib in Adult Patients With Advanced Solid Tumors and Children With Low‐Grade Gliomas von Patel, YT, Daryani, VM, Patel, P, Zhou, D, Fangusaro, J, Carlile, DJ, Martin, PD, Aarons, L, Stewart, CF

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Population Pharmacokinetics of Obinutuzumab (GA101) in Chronic Lymphocytic Leukemia (CLL) and Non‐Hodgkin's Lymphoma and Exposure–Response in CLL von Gibiansky, E, Gibiansky, L, Carlile, D J, Jamois, C, Buchheit, V, Frey, N

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SELECT-2: a phase II, double-blind, randomized, placebo-controlled study to assess the efficacy of selumetinib plus docetaxel as a second-line treatment of patients with advanced o... von Soria, J.-C., Fülöp, A., Maciel, C., Fischer, J.R., Girotto, G., Lago, S., Smit, E., Ostoros, G., Eberhardt, W.E.E., Lishkovska, P., Lovick, S., Mariani, G., McKeown, A., Kilgour, E., Smith, P., Bowen, K., Kohlmann, A., Carlile, D.J., Jänne, P.A.

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Challenges and Opportunities for Quantitative Clinical Pharmacology in Cancer Immunotherapy: Something Old, Something New, Something Borrowed, and Something Blue von Stroh, M, Carlile, DJ, Li, C‐C, Wagg, J, Ribba, B, Ramanujan, S, Jin, J, Xu, J, Charoin, J‐E, Xhu, Z‐X, Morcos, PN, Davis, JD, Phipps, A

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Prediction of Hepatic Clearance from Microsomes, Hepatocytes, and Liver Slices von Brian Houston, J., Carlile, David J.

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Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans von Carlile, David J., Hakooz, Nancy, Bayliss, Martin K., Houston, J. Brian

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Microsomal prediction of in vivo clearance and associated interindividual variability of six benzodiazepines in humans von Rawden, H. C., Carlile, D. J., Tindall, A., Hallifax, D., Galetin, A., Ito, K., Houston, J. B.

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Glofitamab, a Novel, Bivalent CD20-Targeting T-Cell-Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial von Hutchings, Martin, Morschhauser, Franck, Iacoboni, Gloria, Carlo-Stella, Carmelo, Offner, Fritz C., Sureda, Anna, Salles, Gilles, Martinez-Lopez, Joaquin, Crump, Michael, Thomas, Denise N., Morcos, Peter N., Ferlini, Cristiano, Broeske, Ann-Marie E., Belousov, Anton, Bacac, Marina, Dimier, Natalie, Carlile, David J., Lundberg, Linda, Perez-Callejo, David, Umana, Pablo, Moore, Tom, Weisser, Martin, Dickinson, Michael J.

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Implications and consequences of enzyme induction on preclinical and clinical drug development von Worboys, P. D., Carlile, D. J.

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Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells von Andrews, J., Abd-Ellah, M. F., Randolph, N. L., Kenworthy, K. E., Carlile, D. J., Friedberg, T., Houston, J. B.

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Incorporation of in vitro drug metabolism data into physiologically-based pharmacokinetic models von Houston, J.B., Carlile, D.J.

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Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma von Cartron, Guillaume, Hourcade-Potelleret, Florence, Morschhauser, Franck, Salles, Gilles, Wenger, Michael, Truppel-Hartmann, Anna, Carlile, David J

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Kinetics of diazepam metabolism in rat hepatic microsomes and hepatocytes and their use in predicting in vivo hepatic clearance von Zomorodi, K., Carlile, D. J., Houston, J. B.

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Determination of a human hepatic microsomal scaling factor for predicting in vivo drug clearance von HAKOOZ, Nancy, ITO, Kiyomi, RAWDEN, Helen, GILL, Helen, LEMMERS, Lynn, BOOBIS, Alan R, EDWARDS, Robert J, CARLILE, David J, LAKE, Brian G, HOUSTON, J. Brian

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Implications and consequences of enzyme induction on preclinical and clinical drug development: The Drug Metabolism Discussion Group in 2001 von WORBOYS, P. D, CARLILE, D. J

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Terramycin in Serum and Urine After Ingestion of Terramycin Base von Carlile, Jean D., Kester, Alice C., Burr McDonald, C., Clancy, Carl F.

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Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis von Lafaille, Fabien G., Harschnitz, Oliver, Lee, Yoon Seung, Zhang, Peng, Hasek, Mary L., Kerner, Gaspard, Itan, Yuval, Ewaleifoh, Osefame, Rapaport, Franck, Carlile, Thomas M., Carter-Timofte, Madalina E., Paquet, Dominik, Dobbs, Kerry, Zimmer, Bastian, Gao, Daxing, Rojas-Duran, Maria F., Kwart, Dylan, Rattina, Vimel, Ciancanelli, Michael J., McAlpine, Jessica L., Lorenzo, Lazaro, Boucherit, Soraya, Rozenberg, Flore, Halwani, Rabih, Henry, Benoit, Amenzoui, Naima, Alsum, Zobaida, Marques, Laura, Church, Joseph A., Al-Muhsen, Saleh, Tardieu, Marc, Bousfiha, Ahmed Aziz, Paludan, Søren R., Mogensen, Trine Hyrup, Quintana-Murci, Lluis, Tessier-Lavigne, Marc, Smith, Gregory A., Notarangelo, Luigi D., Studer, Lorenz, Gilbert, Wendy, Abel, Laurent, Casanova, Jean-Laurent, Zhang, Shen-Ying

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The European Spallation Source neutrino super-beam conceptual design report von Alekou, A., Baussan, E., Bhattacharyya, A. K., Kraljevic, N. Blaskovic, Blennow, M., Bogomilov, M., Bolling, B., Bouquerel, E., Buchan, O., Burgman, A., Carlile, C. J., Cederkall, J., Christiansen, P., Collins, M., Morales, E. Cristaldo, Cupiał, P., D’Alessi, L., Danared, H., Dancila, D., de André, J. P. A. M., Delahaye, J. P., Dracos, M., Efthymiopoulos, I., Ekelöf, T., Eshraqi, M., Fanourakis, G., Farricker, A., Fernandez-Martinez, E., Folsom, B., Fukuda, T., Gazis, N., Gålnander, B., Geralis, Th, Ghosh, M., Gokbulut, G., Halić, L., Jenssen, M., Topaksu, A. Kayis, Kildetoft, B., Kliček, B., Kozioł, M., Krhač, K., Łacny, Ł., Lindroos, M., Maiano, C., Marrelli, C., Martins, C., Mezzetto, M., Milas, N., Oglakci, M., Ohlsson, T., Olvegård, M., Ota, T., Park, J., Patrzalek, D., Petkov, G., Poussot, P., Johansson, R., Rosauro-Alcaraz, S., Saiang, D., Szybiński, B., Snamina, J., Sosa, A. G., Stavropoulos, G., Stipčević, M., Tarkeshian, R., Terranova, F., Thomas, J., Tolba, T., Trachanas, E., Tsenov, R., Vankova-Kirilova, G., Vassilopoulos, N., Wildner, E., Wurtz, J., Zormpa, O., Zou, Y.

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Optically measured microvascular blood flow contrast of malignant breast tumors von Choe, Regine, Putt, Mary E, Carlile, Peter M, Durduran, Turgut, Giammarco, Joseph M, Busch, David R, Jung, Ki Won, Czerniecki, Brian J, Tchou, Julia, Feldman, Michael D, Mies, Carolyn, Rosen, Mark A, Schnall, Mitchell D, DeMichele, Angela, Yodh, Arjun G

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A phase 1 study of obinutuzumab induction followed by 2 years of maintenance in patients with relapsed CD20-positive B-cell malignancies von Sehn, Laurie H., Assouline, Sarit E., Stewart, Douglas A., Mangel, Joy, Gascoyne, Randy D., Fine, Gregg, Frances-Lasserre, Susan, Carlile, David J., Crump, Michael

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