A Next-Generation Risk Assessment Case Study for Coumarin in Cosmetic Products von Baltazar, Maria T, Cable, Sophie, Carmichael, Paul L, Cubberley, Richard, Cull, Tom, Delagrange, Mona, Dent, Matthew P, Hatherell, Sarah, Houghton, Jade, Kukic, Predrag, Li, Hequn, Lee, Mi-Young, Malcomber, Sophie, Middleton, Alistair M, Moxon, Thomas E, Nathanail, Alexis V, Nicol, Beate, Pendlington, Ruth, Reynolds, Georgia, Reynolds, Joe, White, Andrew, Westmoreland, Carl

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Vision of a near future: Bridging the human health–environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment von Rivetti, Claudia, Allen, Timothy E.H., Brown, James B., Butler, Emma, Carmichael, Paul L., Colbourne, John K., Dent, Matthew, Falciani, Francesco, Gunnarsson, Lina, Gutsell, Steve, Harrill, Joshua A., Hodges, Geoff, Jennings, Paul, Judson, Richard, Kienzler, Aude, Margiotta-Casaluci, Luigi, Muller, Iris, Owen, Stewart F., Rendal, Cecilie, Russell, Paul J., Scott, Sharon, Sewell, Fiona, Shah, Imran, Sorrel, Ian, Viant, Mark R., Westmoreland, Carl, White, Andrew, Campos, Bruno

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Upholding the EU's Commitment to ‘Animal Testing as a Last Resort' Under REACH Requires a Paradigm Shift in How We Assess Chemical Safety to Close the Gap Between Regulatory Testin... von Fentem, Julia, Malcomber, Ian, Maxwell, Gavin, Westmoreland, Carl

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Assuring consumer safety without animals: Applications for tissue engineering von Westmoreland, Carl, Holmes, Anthony M.

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Chemical safety without animals: primary human cells provide mechanistic information for toxicology studies von Westmoreland, Carl, Carmichael, Paul L

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Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment von Adeleye, Yeyejide, Andersen, Melvin, Clewell, Rebecca, Davies, Michael, Dent, Matthew, Edwards, Sue, Fowler, Paul, Malcomber, Sophie, Nicol, Beate, Scott, Andrew, Scott, Sharon, Sun, Bin, Westmoreland, Carl, White, Andrew, Zhang, Qiang, Carmichael, Paul L

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Use of New Approach Methodologies (NAMs) in regulatory decisions for chemical safety: Report from an EPAA Deep Dive Workshop von Westmoreland, Carl, Bender, Hans J., Doe, John E., Jacobs, Miriam N., Kass, George E.N., Madia, Federica, Mahony, Catherine, Manou, Irene, Maxwell, Gavin, Prieto, Pilar, Roggeband, Rob, Sobanski, Tomasz, Schütte, Katrin, Worth, Andrew P., Zvonar, Zvonimir, Cronin, Mark T.D.

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Assuring Consumer Safety Without Animal Testing: A Feasibility Case Study for Skin Sensitisation von Maxwell, Gavin, Aleksic, Maja, Aptula, Aynur, Carmichael, Paul, Fentem, Julia, Gilmour, Nicola, MacKay, Cameron, Pease, Camilla, Pendlington, Ruth, Reynolds, Fiona, Scott, Daniel, Warner, Guy, Westmoreland, Carl

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Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology von Botham, Philip, Cronin, Mark T. D., Currie, Richard, Doe, John, Funk-Weyer, Dorothee, Gant, Timothy W., Leist, Marcel, Marty, Sue, van Ravenzwaay, Bennard, Westmoreland, Carl

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Next generation risk assessment for occupational chemical safety – A real world example with sodium-2-hydroxyethane sulfonate von Wood, Adam, Breffa, Catherine, Chaine, Caroline, Cubberley, Richard, Dent, Matthew, Eichhorn, Joachim, Fayyaz, Susann, Grimm, Fabian A., Houghton, Jade, Kiwamoto, Reiko, Kukic, Predrag, Lee, MoungSook, Malcomber, Sophie, Martin, Suzanne, Nicol, Beate, Reynolds, Joe, Riley, Gordon, Scott, Sharon, Smith, Colin, Westmoreland, Carl, Wieland, Willemien, Williams, Mesha, Wolton, Kathryn, Zellmann, Tristan, Gutsell, Steve

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A PGC-1α-Mediated Transcriptional Network Maintains Mitochondrial Redox and Bioenergetic Homeostasis against Doxorubicin-Induced Toxicity in Human Cardiomyocytes: Implementation of... von Yuan, Haitao, Zhang, Qiang, Guo, Jiabin, Zhang, Tingfen, Zhao, Jun, Li, Jin, White, Andrew, Carmichael, Paul L, Westmoreland, Carl, Peng, Shuangqing

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New approach methodologies (NAMs): identifying and overcoming hurdles to accelerated adoption von Sewell, Fiona, Alexander-White, Camilla, Brescia, Susy, Currie, Richard A, Roberts, Ruth, Roper, Clive, Vickers, Catherine, Westmoreland, Carl, Kimber, Ian

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Ready for regulatory use: NAMs and NGRA for chemical safety assurance von Carmichael, Paul L, Baltazar, Maria T, Cable, Sophie, Cochrane, Stella, Dent, Matthew, Li, Hequn, Middleton, Alistair, Muller, Iris, Reynolds, Georgia, Westmoreland, Carl, White, Andrew

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The last resort requirement under REACH: From principle to practice von Macmillan, Donna S., Bergqvist, Anders, Burgess-Allen, Eleanor, Callan, Ian, Dawick, James, Carrick, Benjamin, Ellis, Graham, Ferro, Roberto, Goyak, Katy, Smulders, Chantal, Stackhouse, Ricky A., Troyano, Espe, Westmoreland, Carl, Ramón, Blanca Serrano, Rocha, Vanessa, Zhang, Xiaoling

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Chemical safety without animals von Westmoreland, Carl, Carmichael, Paul L

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EFFECTS OF MEDIUM COMPOSITION ON THE MORPHOLOGY AND FUNCTION OF RAT HEPATOCYTES CULTURED AS SPHEROIDS AND MONOLAYERS von HAMILTON, GERALDINE A, WESTMORELAND, CARL, GEORGE, ELISABETH

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Aligning the 3Rs with new paradigms in the safety assessment of chemicals von Burden, Natalie, Mahony, Catherine, Müller, Boris P, Terry, Claire, Westmoreland, Carl, Kimber, Ian

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Exposure considerations in human safety assessment: Report from an EPAA Partners’ Forum von Cronin, Mark T.D., Ball, Nicholas, Beken, Sonja, Bender, Hans, Bercaru, Ofelia, Caneva, Laura, Corvaro, Marco, Currie, Richard A., Dawson, Jeffrey L., Desert, Paul, Escher, Sylvia E., Franco, Antonio, Irizar, Amaia, Mehta, Jyotigna M., Rogiers, Vera, Tremblay, Raphaël T., Westmoreland, Carl, Maxwell, Gavin

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A future approach to measuring relative skin sensitising potency: a proposal von Jowsey, Ian R., Basketter, David A., Westmoreland, Carl, Kimber, Ian

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Finding synergies for the 3Rs – Repeated Dose Toxicity testing: Report from an EPAA Partners' Forum von Laroche, Charles, Annys, Erwin, Bender, Hans, Botelho, Danielle, Botham, Phil, Brendler-Schwaab, Susanne, Clayton, Rick, Corvaro, Marco, Dal Negro, Gianni, Delannois, Frédérique, Dent, Matt, Desaintes, Christian, Desprez, Bertrand, Dhalluin, Stephane, Hartmann, Andreas, Hoffmann-Doerr, Simone, Hubesch, Bruno, Irizar, Amaia, Manou, Irene, Müller, Boris P., Nadzialek, Stephanie, Prieto, Pilar, Rasenberg, Mike, Roggeband, Rob, Rowan, Tim G., Schutte, Katrin, van de Water, Bob, Westmoreland, Carl, Whelan, Maurice, Wilschut, Annette, Zvonimir, Zvonar, Cronin, Mark T.D.

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