Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project von Lindon, John C, Nicholson, Jeremy K, Holmes, Elaine, Antti, Henrik, Bollard, Mary E, Keun, Hector, Beckonert, Olaf, Ebbels, Timothy M, Reily, Michael D, Robertson, Donald, Stevens, Gregory J, Luke, Peter, Breau, Alan P, Cantor, Glenn H, Bible, Roy H, Niederhauser, Urs, Senn, Hans, Schlotterbeck, Goetz, Sidelmann, Ulla G, Laursen, Steen M, Tymiak, Adrienne, Car, Bruce D, Lehman-McKeeman, Lois, Colet, Jean-Marie, Loukaci, Ali, Thomas, Craig

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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II von Dinchuk, Joseph E, Car, Bruce D, Focht, Richard J, Johnston, Jennifer J, Jaffee, Bruce D, Covington, Maryanne B, Contel, Nancy R, Eng, Vicki M, Collins, Robert J, Czerniak, Philip M, Gorry, Stewart A, Trzaskos, James M

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IκBα Deficiency Results in a Sustained NF-κB Response and Severe Widespread Dermatitis in Mice von Klement, J. F., Rice, N. R., Car, B. D., Abbondanzo, S. J., Powers, G. D., Bhatt, H., Chen, C.-H., Rosen, C. A., Stewart, C. L.

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The Toxicology of Interleukin-12: A Review von Car, Bruce D., Eng, Vicki M., Lipman, Jack M., Anderson, Timothy D.

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Increased Hepatobiliary Clearance of Unconjugated Thyroxine Determines DMP 904-Induced Alterations in Thyroid Hormone Homeostasis in Rats von Wong, Harvey, Lehman-McKeeman, Lois D., Grubb, Mary F., Grossman, Scott J., Bhaskaran, Vasanthi M., Solon, Eric G., Shen, Helen S. L., Gerson, Ronald J., Car, Bruce D., Zhao, Bitao, Gemzik, Brian

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Reversible drug–induced oxyntic atrophy in rats von Goldenring, James R., Ray, Gregory S., Coffey, Robert J., Meunier, Paul C., Haley, Patrick J., Barnes, T.Bradford, Car, Bruce D.

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Elevated IL-8 and MCP-1 in the bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis von Car, B D, Meloni, F, Luisetti, M, Semenzato, G, Gialdroni-Grassi, G, Walz, A

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Interferon γ receptor deficient mice are resistant to endotoxic shock von CAR, B. D, ENG, V. M, SCHNYDER, B, OZMEN, L, SUI HUANG, GALLAY, P, HEUMANN, D, AGUET, M, RYFFEL, B

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Omeprazole treatment ameliorates oxyntic atrophy induced by DMP-777 von Ogawa, Masako, Nomura, Sachiyo, Car, Bruce D, Goldenring, James R

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Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice von Eugster, Hans-Pietro, Muller, Matthias, Karrer, Urs, Car, Bruce D., Schnyder, Bruno, Eng, Vicki M., Woerly, Gaetane, Hir, Michel Le, Padova, Franco di, Aguet, Michel, Zinkernagel, Rolf, Bluethmann, Horst, Ryffel, Bernhard

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Unique Gene Expression and Hepatocellular Injury in the Lipopolysaccharide-Ranitidine Drug Idiosyncrasy Rat Model: Comparison with Famotidine von Luyendyk, James P., Lehman-McKeeman, Lois D., Nelson, David M., Bhaskaran, Vasanthi M., Reilly, Timothy P., Car, Bruce D., Cantor, Glenn H., Maddox, Jane F., Ganey, Patricia E., Roth, Robert A.

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Role of interferon-gamma in interleukin 12-induced pathology in mice von Car, BD, Eng, VM, Schnyder, B, LeHir, M, Shakhov, AN, Woerly, G, Huang, S, Aguet, M, Anderson, TD, Ryffel, B

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Special Considerations in the Evaluation of the Hematology and Hemostasis of Mutant Mice von Car, B. D., Eng, V. M.

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Interleukin-6 exacerbates glomerulonephritis in (NZB x NZW)F1 mice von Ryffel, B, Car, BD, Gunn, H, Roman, D, Hiestand, P, Mihatsch, MJ

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Detection of in vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches von Espina, J. Robert, Shockcor, John P., Herron, William J., Car, Bruce D., Contel, Nancy R., Ciaccio, Paul J., Lindon, John C., Holmes, Elaine, Nicholson, Jeremy K.

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Inhibition of kinases impairs neutrophil activation and killing of Staphylococcus aureus von Schnyder, B, Meunier, P C, Car, B D

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Cyclooxygenase-2 is essential for normal recovery from 5-fluorouracil–induced myelotoxicity in mice von Lorenz, Meike, Slaughter, Helen S., Wescott, Debra M., Carter, Sherryann I., Schnyder, Bruno, Dinchuk, Joseph E., Car, Bruce D.

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Systemic Neutralization of Interleukin-8 Markedly Reduces Neutrophilic Pleocytosis during Experimental Lipopolysaccharide-Induced Meningitis in Rabbits von DUMONT, Rachel A, CAR, Bruce D, VOITENOK, Nikolai N, JUNKER, Ursula, MOSER, Bernhard, ZAK, Oto, O'REILLY, Terence

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Endotoxin-mediated bovine alveolar macrophage procoagulant induction is dependent on protein kinase C activation von CAR, B. D, SLAUSON, D. O, DORE, M, SUYEMOTO, M. M

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The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo von Eng, V M, Car, B D, Schnyder, B, Lorenz, M, Lugli, S, Aguet, M, Anderson, T D, Ryffel, B, Quesniaux, V F

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