RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance von Balogh, Peter, Adelman, Emmalee R., Pluvinage, John, Capaldo, Brian J., Freeman, Katie C., Singh, Sandeep, Elagib, Kamaleldin E., Nakamura, Yukio, Kurita, Ryo, Sashida, Goro, Zunder, Eli R., Li, Hui, Gru, Alejandro A., Price, Elizabeth A., Schrier, Stanley L., Weissman, Irving L., Figueroa, Maria E., Pang, Wendy W., Goldfarb, Adam N.

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Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL von Jayappa, Kallesh D., Portell, Craig A., Gordon, Vicki L., Capaldo, Brian J., Bekiranov, Stefan, Axelrod, Mark J., Brett, L. Kyle, Wulfkuhle, Julia D., Gallagher, Rosa I., Petricoin, Emanuel F., Bender, Timothy P., Williams, Michael E., Weber, Michael J.

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Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma von Capaldo, Brian J, Roller, Devin, Axelrod, Mark J, Koeppel, Alex F, Petricoin, Emanuel F, Slingluff, Jr, Craig L, Weber, Michael J, Mackey, Aaron J, Gioeli, Daniel, Bekiranov, Stefan

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Isolated BAL Neutrophilia and Unimodal Airway Epithelial IL-13 Inducible Gene Signatures Characterize Children with Treatment-Resistant Asthma von Borish, Larry, MD, FAAAAI, Braciale, Thomas J., MD, PhD, Shirley, Debbie-Ann, MD, Steinke, John W., PhD, FAAAAI, Williams, Sandford, MS, Pollack, Karlyn, BS, Capaldo, Brian J., PhD, Teague, W. Gerald, MD

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Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma von Melssen, Marit M., Olson, Walter, Wages, Nolan A., Capaldo, Brian J., Mauldin, Ileana S., Mahmutovic, Adela, Hutchison, Ciara, Melief, Cornelis J.M., Bullock, Timothy N., Engelhard, Victor H., Slingluff, Craig L.

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Progression of prostate cancer reprograms MYC-mediated lipid metabolism via lysine methyltransferase 2A von Whitlock, Nichelle C., White, Margaret E., Capaldo, Brian J., Ku, Anson T., Agarwal, Supreet, Fang, Lei, Wilkinson, Scott, Trostel, Shana Y., Shi, Zhen-Dan, Basuli, Falguni, Wong, Karen, Jagoda, Elaine M., Kelly, Kathleen, Choyke, Peter L., Sowalsky, Adam G.

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TH1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status von Wisniewski, Julia A., Muehling, Lyndsey M., Eccles, Jacob D., Capaldo, Brian J., Agrawal, Rachana, Shirley, Debbie-Ann, Patrie, James T., Workman, Lisa J., Schuyler, Alexander J., Lawrence, Monica G., Teague, W. Gerald, Woodfolk, Judith A.

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Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy von Wilkinson, Scott, Ye, Huihui, Karzai, Fatima, Harmon, Stephanie A., Terrigino, Nicholas T., VanderWeele, David J., Bright, John R., Atway, Rayann, Trostel, Shana Y., Carrabba, Nicole V., Whitlock, Nichelle C., Walker, Stephanie M., Lis, Rosina T., Abdul Sater, Houssein, Capaldo, Brian J., Madan, Ravi A., Gulley, James L., Chun, Guinevere, Merino, Maria J., Pinto, Peter A., Salles, Daniela C., Kaur, Harsimar B., Lotan, Tamara L., Venzon, David J., Choyke, Peter L., Turkbey, Baris, Dahut, William L., Sowalsky, Adam G.

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Human TH1 and TH2 cells targeting rhinovirus and allergen coordinately promote allergic asthma von Muehling, Lyndsey M., Heymann, Peter W., Wright, Paul W., Eccles, Jacob D., Agrawal, Rachana, Carper, Holliday T., Murphy, Deborah D., Workman, Lisa J., Word, Carolyn R., Ratcliffe, Sarah J., Capaldo, Brian J., Platts-Mills, Thomas A.E., Turner, Ronald B., Kwok, William W., Woodfolk, Judith A.

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Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models von Agarwal, Supreet, Fang, Lei, McGowen, Kerry, Yin, JuanJuan, Bowman, Joel, Ku, Anson T, Alilin, Aian Neil, Corey, Eva, Roudier, Martine P, True, Lawrence D, Dumpit, Ruth, Coleman, Ilsa, Lee, John K, Nelson, Peter S, Capaldo, Brian J, Mariani, Aida, Hoover, Clare, Senatorov, Ilya S, Beshiri, Michael, Sowalsky, Adam G, Hurt, Elaine M, Kelly, Kathleen

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MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity von Whitlock, Nichelle C., Trostel, Shana Y., Wilkinson, Scott, Terrigino, Nicholas T., Hennigan, S. Thomas, Lake, Ross, Carrabba, Nicole V., Atway, Rayann, Walton, Elizabeth D., Gryder, Berkley E., Capaldo, Brian J., Ye, Huihui, Sowalsky, Adam G.

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An integrated framework using high‐dimensional mass cytometry and fluorescent flow cytometry identifies discrete B cell subsets in patients with red meat allergy von Cox, Kelly M., Commins, Scott P., Capaldo, Brian J., Workman, Lisa J., Platts‐Mills, Thomas A. E., Amir, El‐ad D., Lannigan, Josephine A., Schuyler, Alexander J., Erickson, Loren D.

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Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma von Roller, Devin G, Axelrod, Mark, Capaldo, Brian J, Jensen, Karin, Mackey, Aaron, Weber, Michael J, Gioeli, Daniel

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Total Synthesis of a Functional Designer Eukaryotic Chromosome von Annaluru, Narayana, Muller, Héloïse, Mitchell, Leslie A., Ramalingam, Sivaprakash, Stracquadanio, Giovanni, Richardson, Sarah M., Dymond, Jessica S., Kuang, Zheng, Scheifele, Lisa Z., Cooper, Eric M., Cai, Yizhi, Zeller, Karen, Agmon, Neta, Han, Jeffrey S., Hadjithomas, Michalis, Tullman, Jennifer, Caravelli, Katrina, Cirelli, Kimberly, Guo, Zheyuan, London, Viktoriya, Yeluru, Apurva, Murugan, Sindurathy, Kandavelou, Karthikeyan, Agier, Nicolas, Fischer, Gilles, Yang, Kun, Martin, Andrew, Bilgel, Murat, Bohutski, Pavlo, Boulier, Kristin M., Capaldo, Brian J., Chang, Joy, Charoen, Kristie, Choi, Woo Jin, Deng, Peter, DiCarlo, James E., Doong, Judy, Dunn, Jessilyn, Feinberg, Jason I., Fernandez, Christopher, Floria, Charlotte E., Gladowski, David, Hadidi, Pasha, Ishizuka, Isabel, Jabbari, Javaneh, Lau, Calvin Y. L., Lee, Pablo A., Li, Sean, Lin, Denise, Linder, Matthias E., Ling, Jonathan, Liu, Jaime, Liu, Jonathan, London, Mariya, Ma, Henry, Mao, Jessica, McDade, Jessica E., McMillan, Alexandra, Moore, Aaron M., Oh, Won Chan, Ouyang, Yu, Patel, Ruchi, Paul, Marina, Paulsen, Laura C., Qiu, Judy, Rhee, Alex, Rubashkin, Matthew G., Soh, Ina Y., Sotuyo, Nathaniel E., Srinivas, Venkatesh, Suarez, Allison, Wong, Andy, Wong, Remus, Xie, Wei Rose, Xu, Yijie, Yu, Allen T., Koszul, Romain, Bader, Joel S., Boeke, Jef D., Chandrasegaran, Srinivasan

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Human T(H)1 and T(H)2 cells targeting rhinovirus and allergen coordinately promote allergic asthma von Muehling, Lyndsey M., Heymann, Peter W., Wright, Paul W., Eccles, Jacob D., Agrawal, Rachana, Carper, Holliday T., Murphy, Deborah D., Workman, Lisa J., Word, Carolyn R., Ratcliffe, Sarah J., Capaldo, Brian J., Platts-Mills, Thomas A. E., Turner, Ronald B., Kwok, William W., Woodfolk, Judith A.

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Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models von Agarwal, Supreet, Fang, Lei, McGowen, Kerry, Yin, JuanJuan, Bowman, Joel, Ku, Anson T, Alilin, Alan Neil, Corey, Eva, Roudier, Martine R, True, Lawrence D, Dumpit, Ruth, Coleman, Ilsa, Lee, John K, Nelson, Peter S, Capaldo, Brian J, Mariani, Aida, Hoover, Clare, Senatorov, Ilya S, Beshiri, Michael, Sowalsky, Adam G, Hurt, Elaine M, Kelly, Kathleen

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Abstract 2606: Genetic contribution of MYC to the development of primary prostate cancer von Whitlock, Nichelle C., Trostel, Shana, Atway, Rayann, Walton, Elizabeth, Capaldo, Brian J., Ye, Huihui, Sowalsky, Adam G.

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T H 1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status von Wisniewski, Julia A, Muehling, Lyndsey M, Eccles, Jacob D, Capaldo, Brian J, Agrawal, Rachana, Shirley, Debbie-Ann, Patrie, James T, Workman, Lisa J, Schuyler, Alexander J, Lawrence, Monica G, Teague, W Gerald, Woodfolk, Judith A

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Abstract 545: Differential mRNA Expression is Influenced by Apolipoprotein A-I in Order to Promote Foam Cell Regression von Maruko, Elisa C, Xu, Hao, Kaul, Sushma, Capaldo, Brian J, Pamir, Nathalie, Lans, Daniel S, Rich, Stephen S, Thomas, Michael J, Sorci-Thomas, Mary

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Abstract 4166: Integrated molecular profiling of melanoma cell lines reveals genotype-drug phenotype associations giving insight on development of combination therapies von Capaldo, Brian J., Roller, Devin G., Axelrod, Mark, Koeppel, Alex, Weber, Michael J., Mackey, Aaron, Gioeli, Dan, Bekiranov, Stefan

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