Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells von Guzzi, Nicola, Cieśla, Maciej, Ngoc, Phuong Cao Thi, Lang, Stefan, Arora, Sonali, Dimitriou, Marios, Pimková, Kristyna, Sommarin, Mikael N.E., Munita, Roberto, Lubas, Michal, Lim, Yiting, Okuyama, Kazuki, Soneji, Shamit, Karlsson, Göran, Hansson, Jenny, Jönsson, Göran, Lund, Anders H., Sigvardsson, Mikael, Hellström-Lindberg, Eva, Hsieh, Andrew C., Bellodi, Cristian

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Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome von Guzzi, Nicola, Muthukumar, Sowndarya, Cieśla, Maciej, Todisco, Gabriele, Ngoc, Phuong Cao Thi, Madej, Magdalena, Munita, Roberto, Fazio, Serena, Ekström, Simon, Mortera-Blanco, Teresa, Jansson, Monika, Nannya, Yasuhito, Cazzola, Mario, Ogawa, Seishi, Malcovati, Luca, Hellström-Lindberg, Eva, Dimitriou, Marios, Bellodi, Cristian

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Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer von Cieśla, Maciej, Ngoc, Phuong Cao Thi, Cordero, Eugenia, Martinez, Álvaro Sejas, Morsing, Mikkel, Muthukumar, Sowndarya, Beneventi, Giulia, Madej, Magdalena, Munita, Roberto, Jönsson, Terese, Lövgren, Kristina, Ebbesson, Anna, Nodin, Björn, Hedenfalk, Ingrid, Jirström, Karin, Vallon-Christersson, Johan, Honeth, Gabriella, Staaf, Johan, Incarnato, Danny, Pietras, Kristian, Bosch, Ana, Bellodi, Cristian

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Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA von Doan, Phuoc-Loc, Nguyen, Duy-Anh, Le, Quang Thanh, Hoang, Diem-Tuyet Thi, Nguyen, Huu Du, Nguyen, Canh Chuong, Doan, Kim Phuong Thi, Tran, Nhat Thang, Ha, Thi Minh Thi, Trinh, Thu Huong Nhat, Nguyen, Van Thong, Bui, Chi Thuong, Lai, Ngoc-Diep Thi, Duong, Thanh Hien, Mai, Hai-Ly, Huynh, Pham-Uyen Vinh, Huynh, Thu Thanh Thi, Le, Quang Vinh, Vo, Thanh Binh, Dao, Thi Hong-Thuy, Vo, Phuong Anh, Le, Duy-Khang Nguyen, Tran, Ngoc Nhu Thi, Tran, Quynh Nhu Thi, Van, Yen-Linh Thi, Tran, Huyen-Trang Thi, Nguyen, Hoai Thi, Nguyen, Phuong-Uyen, Do, Thanh-Thuy Thi, Truong, Dinh-Kiet, Tang, Hung Sang, Cao, Ngoc-Phuong Thi, Lam, Tuan-Thanh, Tran, Le Son, Nguyen, Hoai-Nghia, Giang, Hoa, Phan, Minh-Duy

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Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations von Nguyen, Hoai-Nghia, Cao, Ngoc-Phuong Thi, Van Nguyen, Thien-Chi, Le, Khang Nguyen Duy, Nguyen, Dat Thanh, Nguyen, Quynh-Tho Thi, Nguyen, Thai-Hoa Thi, Van Nguyen, Chu, Le, Ha Thu, Nguyen, Mai-Lan Thi, Nguyen, Trieu Vu, Tran, Vu Uyen, Luong, Bac An, Le, Linh Gia Hoang, Ho, Quoc Chuong, Pham, Hong-Anh Thi, Vo, Binh Thanh, Nguyen, Luan Thanh, Dang, Anh-Thu Huynh, Nguyen, Sinh Duy, Do, Duc Minh, Do, Thanh-Thuy Thi, Hoang, Anh Vu, Dinh, Kiet Truong, Phan, Minh-Duy, Giang, Hoa, Tran, Le Son

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A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia von Eldeeb, Mohamed, Yuan, Ouyang, Guzzi, Nicola, Thi Ngoc, Phuong Cao, Konturek-Ciesla, Anna, Kristiansen, Trine A., Muthukumar, Sowndarya, Magee, Jeffrey, Bellodi, Cristian, Yuan, Joan, Bryder, David

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The small Cajal body-specific RNA 15 (SCARNA15) directs p53 and redox homeostasis via selective splicing in cancer cells von Beneventi, Giulia, Munita, Roberto, Cao Thi Ngoc, Phuong, Madej, Magdalena, Cieśla, Maciej, Muthukumar, Sowndarya, Krogh, Nicolai, Nielsen, Henrik, Swaminathan, Vinay, Bellodi, Cristian

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Complex Evolutionary Dynamics of Massively Expanded Chemosensory Receptor Families in an Extreme Generalist Chelicerate Herbivore von Ngoc, Phuong Cao Thi, Greenhalgh, Robert, Dermauw, Wannes, Rombauts, Stephane, Bajda, Sabina, Zhurov, Vladimir, Grbić, Miodrag, Van de Peer, Yves, Van Leeuwen, Thomas, Rouzé, Pierre, Clark, Richard M

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Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia von Wong, Regina Wan Ju, Ngoc, Phuong Cao Thi, Leong, Wei Zhong, Yam, Alice Wei Yee, Zhang, Tinghu, Asamitsu, Kaori, Iida, Shinsuke, Okamoto, Takashi, Ueda, Ryuzo, Gray, Nathanael S., Ishida, Takashi, Sanda, Takaomi

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The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia von Tan, Shi Hao, Leong, Wei Zhong, Ngoc, Phuong Cao Thi, Tan, Tze King, Bertulfo, Fatima Carla, Lim, Mei Chee, An, Omer, Li, Zhenhua, Yeoh, Allen Eng Juh, Fullwood, Melissa J., Tenen, Daniel G., Sanda, Takaomi

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Feed-forward regulatory loop driven by IRF4 and NF-κB in adult T-cell leukemia/lymphoma von Wong, Regina Wan Ju, Tan, Tze King, Amanda, Stella, Ngoc, Phuong Cao Thi, Leong, Wei Zhong, Tan, Shi Hao, Asamitsu, Kaori, Hibi, Yurina, Ueda, Ryuzo, Okamoto, Takashi, Ishida, Takashi, Iida, Shinsuke, Sanda, Takaomi

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m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis von Cieśla, Maciej, Ngoc, Phuong Cao Thi, Muthukumar, Sowndarya, Todisco, Gabriele, Madej, Magdalena, Fritz, Helena, Dimitriou, Marios, Incarnato, Danny, Hellström-Lindberg, Eva, Bellodi, Cristian

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ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry von Wang, Lu, Tan, Tze King, Durbin, Adam D., Zimmerman, Mark W., Abraham, Brian J., Tan, Shi Hao, Ngoc, Phuong Cao Thi, Weichert-Leahey, Nina, Akahane, Koshi, Lawton, Lee N., Rokita, Jo Lynne, Maris, John M., Young, Richard A., Look, A. Thomas, Sanda, Takaomi

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Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data von Tran, Ngoc Hieu, Vo, Thanh Binh, Nguyen, Van Thong, Tran, Nhat-Thang, Trinh, Thu-Huong Nhat, Pham, Hong-Anh Thi, Dao, Thi Hong Thuy, Nguyen, Ngoc Mai, Van, Yen-Linh Thi, Tran, Vu Uyen, Vu, Hoang Giang, Bui, Quynh-Tram Nguyen, Vo, Phuong-Anh Ngoc, Nguyen, Huu Nguyen, Nguyen, Quynh-Tho Thi, Do, Thanh-Thuy Thi, Lam, Nien Vinh, Ngoc, Phuong Cao Thi, Truong, Dinh Kiet, Nguyen, Hoai-Nghia, Giang, Hoa, Phan, Minh-Duy

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ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis von Leong, Wei Zhong, Tan, Shi Hao, Ngoc, Phuong Cao Thi, Amanda, Stella, Yam, Alice Wei Yee, Liau, Wei-Siang, Gong, Zhiyuan, Lawton, Lee N, Tenen, Daniel G, Sanda, Takaomi

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Identification of novel lncRNAs regulated by the TAL1 complex in T-cell acute lymphoblastic leukemia von Ngoc, Phuong Cao Thi, Tan, Shi Hao, Tan, Tze King, Chan, Min Min, Li, Zhenhua, Yeoh, Allen. E. J., Tenen, Daniel G, Sanda, Takaomi

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The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma von Phung, Bengt, Cieśla, Maciej, Sanna, Adriana, Guzzi, Nicola, Beneventi, Giulia, Cao Thi Ngoc, Phuong, Lauss, Martin, Cabrita, Rita, Cordero, Eugenia, Bosch, Ana, Rosengren, Frida, Häkkinen, Jari, Griewank, Klaus, Paschen, Annette, Harbst, Katja, Olsson, Håkan, Ingvar, Christian, Carneiro, Ana, Tsao, Hensin, Schadendorf, Dirk, Pietras, Kristian, Bellodi, Cristian, Jönsson, Göran

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Genetic landscape of recessive diseases in the Vietnamese population from large‐scale clinical exome sequencing von Tran, Ngoc Hieu, Nguyen Thi, Thanh‐Huong, Tang, Hung‐Sang, Hoang, Le‐Phuc, Nguyen, Trung‐Hieu Le, Tran, Nhat‐Thang, Trinh, Thu‐Huong Nhat, Nguyen, Van Thong, Nguyen, Bao‐Han Huu, Nguyen, Hieu Trong, Doan, Loc Phuoc, Phan, Ngoc‐Minh, Nguyen, Kim‐Huong Thi, Nguyen, Hong‐Dang Luu, Quach, Minh‐Tam Thi, Nguyen, Thanh‐Phuong Thi, Tran, Vu Uyen, Tran, Dinh‐Vinh, Nguyen, Quynh‐Tho Thi, Do, Thanh‐Thuy Thi, Lam, Nien Vinh, Cao Thi Ngoc, Phuong, Truong, Dinh Kiet, Nguyen, Hoai‐Nghia, Phan, Minh‐Duy, Giang, Hoa

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3077 – FUNCTIONAL AND MOLECULAR IDENTIFICATION OF A FETAL-ASSOCIATED TUMOR SUPPRESSOR AXIS: ABROGATION OF MLL-ENL DRIVEN ACUTE MYELOID LEUKEMIA von Eldeeb, Mohamed, Yuan, Ouyang, Guzzi, Nicola, Ngoc, Phuong Cao Thi, Kristiansen, Trine, Muthukumar, Sowndarya, Bellodi, Cristian, Yuan, Joan, Bryder, David

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Identification of Long Non-Coding RNAs Regulated By the TAL1 Complex in T-Cell Acute Lymphoblastic Leukemia von Tan, Shi Hao, Ngoc, Phuong Cao Thi, Leong, Wei Zhong, Tenen, Daniel G., Sanda, Takaomi

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