Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4 von Ngoei, Kevin R.W., Langendorf, Christopher G., Ling, Naomi X.Y., Hoque, Ashfaqul, Varghese, Swapna, Camerino, Michelle A., Walker, Scott R., Bozikis, Ylva E., Dite, Toby A., Ovens, Ashley J., Smiles, William J., Jacobs, Roxane, Huang, He, Parker, Michael W., Scott, John W., Rider, Mark H., Foitzik, Richard C., Kemp, Bruce E., Baell, Jonathan B., Oakhill, Jonathan S.

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(+)-Fluorenylethylchloroformate (FLEC)--improved synthesis for application in chiral analysis and peptidomimetic synthesis von Camerino, Michelle A, Chalmers, David K, Thompson, Philip E

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The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface von Camerino, Michelle A, Zhong, Nan, Dong, Aiping, Dickson, Bradley M, James, Lindsey I, Baughman, Brandi M, Norris, Jacqueline L, Kireev, Dmitri B, Janzen, William P, Arrowsmith, Cheryl H, Frye, Stephen V

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Crystal structures of human ENPP1 in apo and bound forms von Dennis, Matthew L., Newman, Janet, Dolezal, Olan, Hattarki, Meghan, Surjadi, Regina N., Nuttall, Stewart D., Pham, Tam, Nebl, Tom, Camerino, Michelle, Khoo, Poh Sim, Monahan, Brendon J., Peat, Thomas S.

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(S)-(−)-Fluorenylethylchloroformate (FLEC); preparation using asymmetric transfer hydrogenation and application to the analysis and resolution of amines von Amin, Mohammad A., Camerino, Michelle A., Mountford, Simon J., Ma, Xiao, Manallack, David T., Chalmers, David K., Wills, Martin, Thompson, Philip E.

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Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer von Sharma, Shikhar, Chung, Chi-Yeh, Uryu, Sean, Petrovic, Jelena, Cao, Joan, Rickard, Amanda, Nady, Nataliya, Greasley, Samantha, Johnson, Eric, Brodsky, Oleg, Khan, Showkhin, Wang, Hui, Wang, Zhenxiong, Zhang, Yong, Tsaparikos, Konstantinos, Chen, Lei, Mazurek, Anthony, Lapek, John, Kung, Pei-Pei, Sutton, Scott, Richardson, Paul F., Greenwald, Eric C., Yamazaki, Shinji, Jones, Rhys, Maegley, Karen A., Bingham, Patrick, Lam, Hieu, Stupple, Alexandra E., Kamal, Aileen, Chueh, Anderly, Cuzzupe, Anthony, Morrow, Benjamin J., Ren, Bin, Carrasco-Pozo, Catalina, Tan, Chin Wee, Bhuva, Dharmesh D., Allan, Elizabeth, Surgenor, Elliot, Vaillant, François, Pehlivanoglu, Havva, Falk, Hendrik, Whittle, James R., Newman, Janet, Cursons, Joseph, Doherty, Judy P., White, Karen L., MacPherson, Laura, Devlin, Mark, Dennis, Matthew L., Hattarki, Meghan K., De Silva, Melanie, Camerino, Michelle A., Butler, Miriam S., Dolezal, Olan, Pilling, Patricia, Foitzik, Richard, Stupple, Paul A., Lagiakos, H. Rachel, Walker, Scott R., Hediyeh-Zadeh, Soroor, Nuttall, Stewart, Spall, Sukhdeep K., Charman, Susan A., Connor, Theresa, Peat, Thomas S., Avery, Vicky M., Bozikis, Ylva E., Yang, Yuqing, Zhang, Ming, Monahan, Brendon J., Voss, Anne K., Thomas, Tim, Street, Ian P., Dawson, Sarah-Jane, Dawson, Mark A., Lindeman, Geoffrey J., Davis, Melissa J., Visvader, Jane E., Paul, Thomas A.

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Abstract 1130: First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER+ breast cancer with KAT6A dysregulation von Sharma, Shikhar, Chung, Jay, Uryu, Sean, Rickard, Amanda, Nady, Natalie, Khan, Showkhin, Wang, Zhenxiong, Zhang, Yong, Zhang, Haikuo, Kung, Pei-Pei, Greenwald, Eric, Maegley, Karen, Bingham, Patrick, Lam, Hieu, Bozikis, Ylva E., Falk, Hendrik, Allan, Elizabeth, Avery, Vicky M., Butler, Miriam S., Camerino, Michelle A., Carrasco-Pozo, Catalina, Charman, Susan A., Davis, Melissa J., Dawson, Mark A., Sarah-Jane, Dawson, de Silva, Melanie, Dennis, Matthew L., Dolezal, Olan, Lagiakos, Rachel, Lindeman, Geoffrey J., MacPherson, Laura, Nuttall, Stewart, Peat, Thomas S., Ren, Bin, Stupple, Alexandra E., Surgenor, Elliot, Tan, Chin Wee, Thomas, Tim, Visvader, Jane E., Voss, Anne K., Vaillant, Francois, White, Karen L., Whittle, James, Yang, Yuqing, Hediyeh-Zadeh, Soroor, Stupple, Paul A., Street, Ian P., Monahan, Brendon J., Paul, Thomas

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Solid Phase Synthesis and Circular Dichroism Analysis of (i → i + 4) Cyclic Lactam Analogues of Kisspeptin von Camerino, Michelle A., Kong, David C. M., Chalmers, David K., Thompson, Philip E.

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(+)-Fluorenylethylchloroformate (FLEC) - improved synthesis for application in chiral analysis and peptidomimetic synthesisElectronic supplementary information (ESI) available: Ful... von Camerino, Michelle A, Chalmers, David K, Thompson, Philip E

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Synthesis of Benzyl 2-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)acetate von Camerino, Michelle, Capuano, Ben, Crosby, Ian, Lloyd, Edward

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Abstract 5371: PRMT5 inhibitors as novel treatment for cancers von Falk, Hendrik, Foitzik, Richard C., Allan, Elizabeth, deSilva, Melanie, Yang, Hong, Bozikis, Ylva E., Nikac, Marica, Walker, Scott R., Camerino, Michelle A., Morrow, Ben J., Stupple, Alexandra E., Lagiakos, Rachel, Pinson, Jo-Anne, Lessene, Romina, Kersten, Wilhelmus JA, Ganame, Danny G., Holmes, Ian P., Lunniss, Gill E., Chung, Matthew, Hermans, Stefan J., Parker, Michael W., Thistlethwaite, Alison, White, Karen, Charman, Susan A., Monahan, Brendon J., Pilling, Patricia, Grusovin, Julian, Peat, Thomas S., Sonderegger, Stefan, Toulmin, Emma, Jane, Stephen M., Curtis, David J., Stupple, Paul A., Street, Ian P.

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Abstract 4029: BL-011256 is a novel VEGFR3 selective inhibitor, which suppresses tumor lymphatics and lymph node metastasis in an animal model of melanoma von Leske, Annabell, Foitzik, Richard, Beaumont, Donna, Bentley, John, Bergman, Ylva, Brown, Chloe, Camerino, Michelle, Charman, Susan, Choi, Neil, Silva, Melanie D., Chung, Matthew, Falk, Hendrik, Ganame, Danny, Gregg, Alison, Grusovin, Julian, Harvey, Andrew, Hemley, Catherine, Holmes, Ian, Huff, Belinda, Inglis, Daniel, Kersten, Wilhelmus, Lavranos, Tina, Lessene, Romina, Lunniss, Gillian, Monahan, Brendon, Morrow, Benjamin, Nikac, Marica, Nikolakopoulos, George, Paul, Dharam, Peat, Tom, Ripper, Justin, Scherer, Michaela, Stupple, Paul, White, Karen, Street, Ian, Kremmidiotis, Gabriel

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Selective Inhibitors of Arginine Methyl Transferase 5 (PRMT5) As a Novel Treatment for β-Thalassemia and Sickle Cell Disease von Street, Ian, Monahan, Brendon, Falk, Hendrik, Allan, Elizabeth, Bergman, Ylva, Stupple, Paul, Holmes, Ian, Gregg, Alison, Charman, Susan, Lackovic, Kurt, Peat, Tom, Walker, Scott, Lowes, Kym, Kersten, Wilco, Alcindor, Jo, Chung, Matthew, Parker, Michael, Foitzik, Richard, Camerino, Michelle, Nikac, Marcia, Grusovin, Julian, Pilling, Pat, Sonderegger, Stefan, Tan, Yuen, Zhao, Quan, Curtis, David J., Jane, Stephen M

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The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interfaceElectronic supplementary information (ESI) available: Experimental procedures includin... von Camerino, Michelle A, Zhong, Nan, Dong, Aiping, Dickson, Bradley M, James, Lindsey I, Baughman, Brandi M, Norris, Jacqueline L, Kireev, Dmitri B, Janzen, William P, Arrowsmith, Cheryl H, Frye, Stephen V

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Substituted condensed thiophenes as modulators of STING von STUPPLE, Paul, MORROW, Benjamin, CAMERINO, Michelle, WALKER, Scott, STEVENSON, Graeme

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COMPOUNDS von FOITZIK, Richard, HEMLEY, Catherine, STUPPLE, Paul, MORROW, Benjamin, CAMERINO, Michelle, WALKER, Scott, LAGIAKOS, Helen, BOZIKIS, Ylva

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SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING von STUPPLE, Paul, Anthony, CAMERINO, Michelle, Ang, MORROW, Benjamin, Joseph, STEVENSON, Graeme, Irvine, WALKER, Scott, Raymond

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SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING von Camerino, Michelle Ang, Morrow, Benjamin Joseph, Stevenson, Graeme Irvine, Walker, Scott Raymond, Stupple, Paul Anthony

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Substituted condensed thiophenes as modulators of sting von Camerino, Michelle Ang, Morrow, Benjamin Joseph, Stevenson, Graeme Irvine, Walker, Scott Raymond, Stupple, Paul Anthony

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COMPOUNDS von CAMERINO, Michelle Ang, HUBERT, Jonathan Grant, DENNIS, Matthew Lloyd, STUPPLE, Paul Anthony, CUZZUPE, Anthony Nicholas, MORROW, Benjamin Joseph

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